|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.971
|
|
|
|
regulation of sodium dependent phosphate transport
|
GO:2000118 |
2 |
0.895
|
|
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.873
|
|
|
|
spemann organizer formation
|
GO:0060061 |
1 |
0.863
|
|
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.826
|
|
|
|
wnt signaling pathway calcium modulating pathway
|
GO:0007223 |
2 |
0.785
|
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.735
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.695
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.679
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.663
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.650
|
|
|
|
regulation of ectodermal cell fate specification
|
GO:0042665 |
1 |
0.645
|
|
|
|
negative regulation of ectodermal cell fate specification
|
GO:0042666 |
1 |
0.594
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.581
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.560
|
Fly |
|
|
ectodermal cell fate commitment
|
GO:0001712 |
1 |
0.556
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
12 |
0.509
|
|
|
|
complement activation
|
GO:0006956 |
19 |
0.464
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.446
|
|
|
|
autocrine signaling
|
GO:0035425 |
2 |
0.425
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.414
|
Fly |
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.406
|
Fly |
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.405
|
Fly |
|
|
negative regulation of sodium dependent phosphate transport
|
GO:2000119 |
1 |
0.401
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.400
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.384
|
Mouse Fly |
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.373
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.371
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.352
|
Fly |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.332
|
|
|
|
complement activation lectin pathway
|
GO:0001867 |
7 |
0.326
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.322
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.315
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.305
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.302
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.286
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.286
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.285
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.285
|
Fly |
|
|
negative regulation of ectoderm development
|
GO:2000384 |
1 |
0.272
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.272
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.266
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.258
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.247
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.246
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.240
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.236
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.235
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.231
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.230
|
Human |
|
|
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment
|
GO:0061317 |
3 |
0.227
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.223
|
Human |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.223
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.221
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.206
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.204
|
Fly |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.203
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.203
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.201
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.196
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.195
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.195
|
Fly |
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.192
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.190
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.190
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.190
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.184
|
|
|
|
non canonical wnt signaling pathway via jnk cascade
|
GO:0038031 |
3 |
0.184
|
|
|
|
negative regulation of protein activation cascade
|
GO:2000258 |
7 |
0.183
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.183
|
|
|
|
ectodermal cell fate specification
|
GO:0001715 |
1 |
0.182
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.179
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.175
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.175
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.172
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.172
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.171
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.171
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.169
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.165
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.164
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.164
|
Human |
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.163
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.159
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.156
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.154
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.152
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.152
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.151
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.151
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.150
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.149
|
Mouse |
|
|
neurological system process
|
GO:0050877 |
163 |
0.148
|
Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.147
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.146
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.146
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.146
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.145
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.145
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.144
|
|
|
|
regulation of ectoderm development
|
GO:2000383 |
1 |
0.144
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.143
|
Fly |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.143
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.139
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.137
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.137
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.134
|
Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.134
|
Fly |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.131
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.131
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.130
|
Mouse |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.129
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.129
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.128
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.126
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.125
|
Fly |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.125
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.124
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.121
|
Fly |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.121
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.120
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.120
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.119
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.118
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.117
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.116
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.115
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.114
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.114
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.114
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.113
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.113
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.112
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.111
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.110
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.110
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.110
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.110
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.109
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.109
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.107
|
Human |
|
|
protein activation cascade
|
GO:0072376 |
22 |
0.107
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.106
|
Fly |
|
|
receptor internalization
|
GO:0031623 |
43 |
0.106
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.106
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.105
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.105
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.105
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.105
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.104
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.104
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.104
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.104
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.104
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.103
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.103
|
Fly |
|
|
immune effector process
|
GO:0002252 |
159 |
0.102
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.102
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.101
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.100
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.100
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.100
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.100
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.099
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.097
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.097
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.095
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.095
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.095
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.094
|
Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.093
|
Human |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.093
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.092
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.092
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.090
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.090
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.090
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.089
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.089
|
Human |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.088
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.088
|
Fly |
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.087
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.087
|
|
|
|
inorganic anion transport
|
GO:0015698 |
60 |
0.086
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.086
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.085
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.084
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.084
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.083
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.082
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.082
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.080
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.080
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.079
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
28 |
0.079
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.078
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.078
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.077
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.077
|
Fly |
|
|
thymus development
|
GO:0048538 |
3 |
0.075
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.074
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.074
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.073
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.073
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.073
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.072
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.072
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.071
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.071
|
Human |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.070
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.070
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.070
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.069
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.069
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.069
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.068
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.067
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.066
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.066
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.066
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.066
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.066
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.065
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.065
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.065
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.065
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.065
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.065
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.065
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.064
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.064
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.064
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.064
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.064
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.064
|
|
|
|
regulation of response to drug
|
GO:2001023 |
3 |
0.063
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.063
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.062
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.061
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.061
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.061
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.060
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.060
|
Mouse |
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.060
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.060
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.060
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.060
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.059
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.059
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.059
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.058
|
Human |
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.058
|
|
|
|
neuronal ion channel clustering
|
GO:0045161 |
2 |
0.058
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.058
|
Fly |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.058
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.057
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.057
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.057
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.057
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.057
|
|
|
|
nadph oxidation
|
GO:0070995 |
3 |
0.057
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.057
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.056
|
Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.056
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.056
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.056
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.056
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.056
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.056
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.056
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.055
|
|
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.055
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.055
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.055
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.055
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.055
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.054
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.053
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.053
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.053
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.053
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.053
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.053
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.052
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.052
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.052
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.052
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.051
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.051
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.051
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.050
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.050
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.050
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.050
|
Fly |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.050
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.050
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.049
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.049
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.049
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.048
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.048
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.048
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.048
|
Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.047
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.047
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.047
|
Mouse Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.047
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.047
|
Fly |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.047
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.046
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.046
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.046
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.046
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.046
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.046
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.046
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.045
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.045
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.045
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.045
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.044
|
Human |
|
|
associative learning
|
GO:0008306 |
1 |
0.044
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.044
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.043
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.043
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.043
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.043
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.043
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.042
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.042
|
Mouse |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.042
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.042
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.042
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
0.042
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.042
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.041
|
Human |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.041
|
|
|
|
growth
|
GO:0040007 |
202 |
0.041
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.040
|
|
|
|
regulation of complement activation
|
GO:0030449 |
8 |
0.040
|
|
|
|
secondary heart field specification
|
GO:0003139 |
2 |
0.040
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.040
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.040
|
Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.039
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.039
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.039
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.039
|
Fly |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.039
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.039
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.038
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.038
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.038
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
1 |
0.038
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.037
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.037
|
Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.037
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.037
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
13 |
0.037
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.037
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.037
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.037
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.037
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.037
|
Human |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.036
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.036
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.036
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.036
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.036
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.035
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.035
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.035
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.035
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.035
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.035
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.034
|
Human |
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.034
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.034
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.034
|
|
|
|
negative chemotaxis
|
GO:0050919 |
11 |
0.034
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.034
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.033
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.033
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003256 |
3 |
0.033
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.033
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.033
|
Human |
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.033
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.033
|
|
|
|
negative regulation of blood circulation
|
GO:1903523 |
4 |
0.033
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.033
|
Fly |
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.033
|
|
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.033
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.033
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.032
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.032
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.032
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.032
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.032
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.032
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.032
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.032
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.032
|
|
|
|
regulation of heart rate
|
GO:0002027 |
38 |
0.032
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
1 |
0.031
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.031
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.031
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.031
|
Human |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.031
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.031
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.031
|
Fly |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.031
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.031
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.031
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.031
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.031
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
2 |
0.031
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.031
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.031
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.031
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.030
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.030
|
Fly |
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.030
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.029
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.029
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.029
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.029
|
Human |
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.029
|
Mouse |
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.029
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.029
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.028
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.028
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.028
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.028
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.027
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.027
|
|
|
|
ventral spinal cord interneuron differentiation
|
GO:0021514 |
1 |
0.027
|
|
|
|
enteric nervous system development
|
GO:0048484 |
1 |
0.027
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
2 |
0.027
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.027
|
Mouse |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.027
|
Fly |
|
|
startle response
|
GO:0001964 |
3 |
0.027
|
|
|
|
anion homeostasis
|
GO:0055081 |
18 |
0.026
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.026
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.026
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.026
|
Human |
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.026
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
2 |
0.026
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.026
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.026
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.025
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.025
|
|
|
|
nephric duct development
|
GO:0072176 |
4 |
0.025
|
|
|
|
positive regulation of epidermis development
|
GO:0045684 |
11 |
0.025
|
|
|
|
positive regulation of plasminogen activation
|
GO:0010756 |
3 |
0.025
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.025
|
Human |
|
|
heart contraction
|
GO:0060047 |
62 |
0.025
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.025
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.025
|
Human |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.025
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.025
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.024
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.024
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.024
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.024
|
|
|
|
protein localization to microtubule cytoskeleton
|
GO:0072698 |
10 |
0.024
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.024
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.024
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.024
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.024
|
Human |
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.024
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.024
|
|
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.024
|
|
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.024
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.023
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.023
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.023
|
|
|
|
negative regulation of heart contraction
|
GO:0045822 |
3 |
0.023
|
|
|
|
negative regulation of dendrite development
|
GO:2000171 |
5 |
0.023
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.023
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
15 |
0.023
|
|
|
|
positive regulation of epidermal cell differentiation
|
GO:0045606 |
8 |
0.023
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.023
|
|
|
|
mating
|
GO:0007618 |
1 |
0.023
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.023
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.023
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.023
|
|
|
|
acute inflammatory response
|
GO:0002526 |
21 |
0.022
|
|
|
|
negative regulation of complement activation
|
GO:0045916 |
7 |
0.022
|
|
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.022
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.022
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.022
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.022
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.022
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.022
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.022
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
7 |
0.022
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.022
|
Fly |
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.022
|
|
