|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.965
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.745
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.729
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.706
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.564
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.470
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.440
|
Human Fly |
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.429
|
|
|
|
growth
|
GO:0040007 |
202 |
0.412
|
Rat Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.387
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.369
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.323
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.307
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.302
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.299
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.266
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.260
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.256
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.252
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.251
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.249
|
Worm |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.249
|
Worm Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.249
|
Worm Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.245
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.233
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.229
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.220
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.217
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.217
|
Human |
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.213
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.211
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.202
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.199
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.194
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.185
|
Human |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.180
|
Human Worm |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.179
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.165
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.160
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.157
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.150
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.148
|
Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.148
|
Mouse Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.146
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.143
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.141
|
Human |
|
|
developmental growth
|
GO:0048589 |
48 |
0.138
|
Rat Fly |
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.137
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.130
|
Mouse Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.129
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.125
|
Worm |
|
|
rna interference
|
GO:0016246 |
4 |
0.124
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.123
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.122
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.121
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.119
|
Fly |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.114
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.111
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.101
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.100
|
Rat Worm |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.098
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.097
|
Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.095
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.093
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.092
|
Worm Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.091
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.091
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.091
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.090
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.088
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.086
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.086
|
Fly |
|
|
rna processing
|
GO:0006396 |
255 |
0.083
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.083
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.082
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.081
|
|
|
|
translational initiation
|
GO:0006413 |
48 |
0.080
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.079
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.076
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.076
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.076
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.075
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.075
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.073
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.073
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.072
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.070
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.069
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.067
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.067
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.065
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.065
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.064
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.062
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.062
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.062
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.062
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.061
|
Rat |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.061
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.061
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.061
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.060
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.060
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.059
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.059
|
Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.058
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.058
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.057
|
Human |
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.057
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.057
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.057
|
Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.056
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.056
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.056
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.055
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.054
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.054
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.054
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.053
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.053
|
Human Worm |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.053
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.053
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.053
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.052
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.051
|
Fly |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.051
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.050
|
Rat |
|
|
viral process
|
GO:0016032 |
146 |
0.050
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.049
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.049
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.048
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.048
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.048
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.048
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.047
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.047
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.046
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.046
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.046
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.046
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.046
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.046
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.045
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.045
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.045
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.044
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.043
|
Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.043
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.043
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.043
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.043
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.043
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.043
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.043
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.042
|
Human |
|
|
reproductive system development
|
GO:0061458 |
56 |
0.042
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.042
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.042
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.041
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.040
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.040
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.040
|
Rat |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.039
|
Human Rat |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.039
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.039
|
Rat |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.038
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.038
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.038
|
Worm Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.038
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.038
|
Worm Fly |
|
|
response to starvation
|
GO:0042594 |
59 |
0.037
|
Worm Fly |
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.037
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.037
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.037
|
|
|
|
ribonucleoside bisphosphate metabolic process
|
GO:0033875 |
7 |
0.037
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.037
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.036
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.036
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.036
|
Rat |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.036
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.036
|
Worm |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.036
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.035
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.035
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.035
|
Rat Worm Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.035
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.034
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.034
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.034
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.034
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.034
|
Worm Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.033
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.033
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.033
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.033
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.033
|
Rat |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.033
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.032
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.032
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.032
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.031
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.031
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.031
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.031
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.031
|
Human |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.031
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.031
|
Human |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.031
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.030
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.030
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.030
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.030
|
Rat |
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.029
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.029
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.029
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.029
|
Rat |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.028
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.028
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.028
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.028
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.028
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.028
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.028
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.028
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.028
|
Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.028
|
Rat |
|
|
aging
|
GO:0007568 |
66 |
0.028
|
Rat Worm Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.028
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.028
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.028
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.027
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.027
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.027
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.027
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.027
|
Fly |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.027
|
Worm Fly |
|
|
nuclear import
|
GO:0051170 |
106 |
0.026
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.026
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.026
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.026
|
|
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.026
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.026
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.026
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.025
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.025
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.025
|
Human |
|
|
ncrna processing
|
GO:0034470 |
83 |
0.025
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.025
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.025
|
Rat |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.025
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.025
|
Fly |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.025
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.024
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.024
|
Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.024
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.024
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.024
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.024
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.024
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.024
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.024
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.024
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.023
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.023
|
|
|
|
translation
|
GO:0006412 |
132 |
0.023
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.023
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.023
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.023
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.023
|
|
|
|
nuclear transcribed mrna catabolic process
|
GO:0000956 |
48 |
0.023
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.022
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.022
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.022
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.022
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.022
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.022
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.022
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.022
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.022
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.022
|
|
|
|
system process
|
GO:0003008 |
349 |
0.021
|
Rat |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.021
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.021
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.021
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.021
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.021
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.021
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.021
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.021
|
|
|
|
ribosome biogenesis
|
GO:0042254 |
48 |
0.021
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.021
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.020
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.020
|
Rat |
|
|
nuclear division
|
GO:0000280 |
128 |
0.020
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.020
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.020
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.020
|
Rat Fly |
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.020
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.020
|
Mouse |
|
|
nuclear export
|
GO:0051168 |
69 |
0.020
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.020
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.019
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.019
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.019
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.019
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.019
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.019
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.019
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.019
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.019
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.019
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.018
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.018
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.018
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.018
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.018
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.018
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.018
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.018
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.018
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.018
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.018
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.018
|
|
|
|
glycosyl compound biosynthetic process
|
GO:1901659 |
27 |
0.018
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.018
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.018
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.017
|
Fly |
|
|
amino acid transmembrane transport
|
GO:0003333 |
20 |
0.017
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.017
|
Rat |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.017
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.017
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.017
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.017
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.017
|
Human |
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.017
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.017
|
Human |
|
|
purine nucleoside bisphosphate metabolic process
|
GO:0034032 |
7 |
0.017
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.017
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.017
|
Mouse Fly |
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.017
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.017
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.017
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.017
|
Human |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.017
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.016
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.016
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.016
|
Fly |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.016
|
Fly |
|
|
cell activation
|
GO:0001775 |
213 |
0.016
|
Human |
|
|
nucleoside bisphosphate biosynthetic process
|
GO:0033866 |
4 |
0.016
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.016
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.016
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.016
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.016
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.016
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.016
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.016
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.016
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.016
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.016
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.016
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.016
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.015
|
|
|
|
coenzyme a biosynthetic process
|
GO:0015937 |
4 |
0.015
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
24 |
0.015
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.015
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.015
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.015
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.015
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.015
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.015
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.015
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.015
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.015
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.015
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.015
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.015
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.015
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.015
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.015
|
Worm Fly |
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.015
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
4 |
0.014
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.014
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.014
|
Fly |
|
|
response to virus
|
GO:0009615 |
126 |
0.014
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.014
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.014
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.014
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.014
|
Worm |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.014
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.014
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.014
|
Human |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.014
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.014
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.014
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.014
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.014
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.013
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.013
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.013
|
Rat |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.013
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.013
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.013
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.013
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.013
|
Mouse |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.013
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.013
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.013
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.013
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.013
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.013
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.013
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.013
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.013
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.013
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.013
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.013
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.013
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.013
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.013
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.013
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.013
|
Worm Fly |
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.013
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.012
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.012
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.012
|
Rat |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.012
|
|
|
|
ribonucleoside bisphosphate biosynthetic process
|
GO:0034030 |
4 |
0.012
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.012
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.012
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.012
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.012
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.012
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.012
|
Mouse Worm Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.012
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.012
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.012
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.012
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.012
|
Human |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.012
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.012
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.012
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.011
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.011
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.011
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.011
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.011
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.011
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.011
|
Human |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.011
|
Mouse Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.011
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.011
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.011
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.011
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.011
|
Fly |
|
|
protein import
|
GO:0017038 |
130 |
0.011
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.011
|
Rat |
|
|
dna repair
|
GO:0006281 |
198 |
0.011
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.011
|
Mouse |
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.011
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.011
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.011
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.011
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.011
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.011
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.011
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.011
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.011
|
Human |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.011
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.011
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.011
|
|
|
|
regulation of cell size
|
GO:0008361 |
19 |
0.011
|
Fly |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.010
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
28 |
0.010
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.010
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.010
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.010
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.010
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.010
|
Worm Fly |
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.010
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.010
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.010
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
24 |
0.010
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.010
|
Worm Fly |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.010
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.010
|
|
