|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.998
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.997
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.995
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.993
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.991
|
Mouse |
|
|
cardiac ventricle formation
|
GO:0003211 |
2 |
0.988
|
|
|
|
regulation of thyroid hormone generation
|
GO:2000609 |
2 |
0.988
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.988
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.988
|
Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.986
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.986
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.986
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.984
|
Mouse Fly |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.983
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.982
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.982
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.977
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.976
|
Fly |
|
|
basophil differentiation
|
GO:0030221 |
2 |
0.972
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.971
|
|
|
|
cardiac chamber formation
|
GO:0003207 |
2 |
0.971
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.968
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.968
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.964
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
2 |
0.963
|
Mouse |
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.962
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.952
|
Mouse |
|
|
aortic valve development
|
GO:0003176 |
3 |
0.948
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.945
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.943
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.941
|
Mouse Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.939
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.939
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.937
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.935
|
|
|
|
cardiac left ventricle formation
|
GO:0003218 |
1 |
0.932
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.928
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.921
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.915
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.913
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.911
|
Mouse Fly |
|
|
digestive system development
|
GO:0055123 |
75 |
0.905
|
Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.903
|
Mouse |
|
|
tube development
|
GO:0035295 |
125 |
0.902
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.902
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.901
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.895
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.893
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.889
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.887
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.886
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.885
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.885
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.877
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.874
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.871
|
Mouse Fly |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.867
|
Fly |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.862
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.860
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.853
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.852
|
Mouse |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.846
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.843
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.836
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.836
|
|
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.835
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.830
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.830
|
Fly |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.822
|
Human |
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.820
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.817
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.816
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.814
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.804
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.796
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.794
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.793
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.789
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.784
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.784
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.775
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.773
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.772
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.772
|
|
|
|
eosinophil differentiation
|
GO:0030222 |
2 |
0.770
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.763
|
|
|
|
platelet formation
|
GO:0030220 |
4 |
0.758
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.756
|
Mouse |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.754
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.744
|
Fly |
|
|
gastrulation
|
GO:0007369 |
51 |
0.737
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.734
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.732
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.731
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.731
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.728
|
|
|
|
erythrocyte maturation
|
GO:0043249 |
1 |
0.717
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.711
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.709
|
Mouse Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.706
|
Fly |
|
|
positive regulation of monocyte chemotactic protein 1 production
|
GO:0071639 |
3 |
0.705
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.695
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.695
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.690
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.684
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.683
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.682
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.670
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.666
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.658
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.647
|
|
|
|
intracellular bile acid receptor signaling pathway
|
GO:0038185 |
1 |
0.643
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.641
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.636
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.634
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.629
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.625
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.615
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.613
|
Mouse Fly |
|
|
negative regulation of bile acid biosynthetic process
|
GO:0070858 |
3 |
0.602
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.592
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.590
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.588
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.585
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.576
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.573
|
Fly |
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.569
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.568
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.568
|
Mouse |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.567
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.567
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.567
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.565
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.564
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.561
|
|
|
|
system process
|
GO:0003008 |
349 |
0.558
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.557
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.545
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.542
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.542
|
Mouse Fly |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.534
|
Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.531
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.529
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.523
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.521
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.520
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.517
|
Fly |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.515
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.514
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.499
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.497
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.497
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.495
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.493
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.486
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.483
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.479
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.478
|
Fly |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.471
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.461
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.456
|
Mouse |
|
|
wound healing
|
GO:0042060 |
115 |
0.454
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.451
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.450
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.448
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.442
|
Mouse Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.437
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.437
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.426
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.424
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.421
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.420
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.417
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.416
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.415
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.411
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.409
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.402
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.396
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.394
|
|
|
|
negative regulation of histone phosphorylation
|
GO:0033128 |
2 |
0.391
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.387
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.387
|
Mouse |
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.381
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.376
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.374
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.368
|
Human |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.365
|
|
|
|
growth
|
GO:0040007 |
202 |
0.362
|
Worm |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.361
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.361
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.361
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.361
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.357
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.357
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.353
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.352
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.337
|
Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.337
|
Mouse Fly |
|
|
nerve development
|
GO:0021675 |
4 |
0.336
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.335
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.332
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.329
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.328
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.327
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.325
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.324
|
Mouse |
|
|
platelet morphogenesis
|
GO:0036344 |
4 |
0.323
|
|
|
|
aortic valve morphogenesis
|
GO:0003180 |
3 |
0.320
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.318
|
Worm |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.311
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.308
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.305
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.304
|
Mouse |
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.304
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.298
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.296
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.296
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.296
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.296
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.295
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.295
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.291
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.288
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.288
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.288
|
|
|
|
cardiac vascular smooth muscle cell differentiation
|
GO:0060947 |
2 |
0.286
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.285
|
|
|
|
negative regulation of cellular senescence
|
GO:2000773 |
5 |
0.284
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.284
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.283
|
Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.281
|
Mouse |
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.278
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.277
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.277
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.271
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.271
|
Fly |
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.269
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.268
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.263
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.263
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.262
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.258
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.257
|
|
|
|
head development
|
GO:0060322 |
108 |
0.256
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.255
|
Mouse Worm Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.255
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.250
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.249
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.248
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.247
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.245
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.245
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.245
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.243
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.243
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.243
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.242
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.236
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.236
|
|
|
|
pancreas development
|
GO:0031016 |
19 |
0.235
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.234
|
Mouse |
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.232
|
Mouse |
|
|
optic nerve development
|
GO:0021554 |
2 |
0.230
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.230
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.228
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.227
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.227
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.226
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.226
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.226
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.225
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.225
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.224
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.221
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.220
|
Mouse Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.219
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.218
|
|
|
|
eyelid development in camera type eye
|
GO:0061029 |
2 |
0.217
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.216
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.214
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.214
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.213
|
|
|
|
nk t cell proliferation
|
GO:0001866 |
3 |
0.213
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.212
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.211
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.210
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.208
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.206
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.205
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.204
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.203
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.203
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.202
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.199
|
Worm Fly |
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.197
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.194
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.193
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.193
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.193
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.192
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.192
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.192
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.191
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.191
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.191
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.190
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.190
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.189
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.188
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.184
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.182
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.181
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.181
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.181
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.180
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.180
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.179
|
Fly |
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.177
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.176
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.175
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.174
|
Fly |
|
|
eye development
|
GO:0001654 |
42 |
0.173
|
Fly |
|
|
response to drug
|
GO:0042493 |
81 |
0.173
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.172
|
Mouse |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.171
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.170
|
|
|
|
response to low density lipoprotein particle
|
GO:0055098 |
4 |
0.169
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.166
|
Fly |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.165
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.164
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.164
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
16 |
0.164
|
|
|
|
erythrocyte development
|
GO:0048821 |
3 |
0.162
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.161
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.161
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.161
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.159
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.158
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.158
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.158
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.158
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.157
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.157
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.156
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.156
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.155
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.155
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.152
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.151
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.150
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.149
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.148
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.148
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.147
|
Fly |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.147
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.143
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.143
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.142
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.141
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.140
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.140
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.140
|
Fly |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.140
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.139
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.138
|
Fly |
|
|
camera type eye development
|
GO:0043010 |
25 |
0.138
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.137
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.137
|
Mouse |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.137
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.136
|
|
|
|
embryonic retina morphogenesis in camera type eye
|
GO:0060059 |
1 |
0.135
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.135
|
|
|
|
mammary gland development
|
GO:0030879 |
17 |
0.134
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.134
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.133
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.132
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.132
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.131
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.130
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.130
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.129
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.129
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.129
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.128
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.127
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.126
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.124
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.123
|
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
71 |
0.123
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.122
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.122
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.122
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.121
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.120
|
|
|
|
regulation of fatty acid beta oxidation
|
GO:0031998 |
8 |
0.120
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.120
|
|
|
|
hippo signaling
|
GO:0035329 |
20 |
0.120
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.119
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.119
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.118
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.117
|
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.117
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.117
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.115
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.115
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.115
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.114
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.114
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.113
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.113
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.112
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.111
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.111
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.110
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.110
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.109
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.109
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.108
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.108
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.107
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.106
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.106
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.106
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.105
|
Mouse |
|
|
protein deacylation
|
GO:0035601 |
39 |
0.105
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.104
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.103
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.103
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.103
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.102
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.102
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.102
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.101
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.101
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.101
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.100
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.100
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.100
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.099
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.099
|
Mouse |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.099
|
|
|
|
positive regulation of interleukin 6 secretion
|
GO:2000778 |
6 |
0.099
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.098
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.098
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.097
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.097
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.097
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.096
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.096
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.096
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.095
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.094
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.094
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.094
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.093
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.092
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.092
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.092
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.091
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.091
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.090
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.090
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.089
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.089
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.087
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.086
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.086
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.086
|
|
|
|
regulation of stem cell maintenance
|
GO:2000036 |
4 |
0.086
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.085
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.085
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.085
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.085
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.084
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.084
|
Fly |
|
|
negative regulation of histone modification
|
GO:0031057 |
19 |
0.084
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.083
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.083
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.083
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.083
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.083
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.082
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.082
|
|
|
|
digestive system process
|
GO:0022600 |
17 |
0.082
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.082
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.081
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.081
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.081
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.080
|
|
|
|
positive regulation of transcription regulatory region dna binding
|
GO:2000679 |
8 |
0.080
|
|
|
|
gabaergic neuron differentiation
|
GO:0097154 |
1 |
0.080
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.080
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.080
|
|
