|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.997
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.932
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.916
|
|
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.897
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.800
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.795
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.735
|
Fly |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.730
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.701
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.691
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.655
|
Fly |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.631
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.622
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.620
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.616
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.601
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.590
|
Fly |
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.579
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.542
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.489
|
Fly |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.447
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.443
|
Fly |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.438
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.419
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.395
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.389
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.378
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.376
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.355
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.353
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.352
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.314
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.284
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.280
|
Fly |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.277
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.277
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.277
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.273
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.271
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.257
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.254
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.253
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.252
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.250
|
Fly |
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.249
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.247
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.243
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.243
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.243
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.240
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.238
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.236
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.229
|
Fly |
|
|
histone h2a monoubiquitination
|
GO:0035518 |
11 |
0.220
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.217
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.217
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.212
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.202
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.201
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.198
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.197
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.191
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.188
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.186
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.180
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.172
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.165
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.164
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.161
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.160
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.159
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.158
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.140
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.139
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.138
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.136
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.136
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.132
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.130
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.127
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.127
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.121
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.120
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.118
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.117
|
Fly |
|
|
dna replication
|
GO:0006260 |
116 |
0.117
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.114
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.113
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.111
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.111
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.110
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.109
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.108
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.108
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.106
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.103
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.101
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.101
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.100
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.099
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.098
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.097
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.097
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.096
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.094
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.093
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.092
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.091
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.090
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.089
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.087
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.087
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.086
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.085
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.085
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.084
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.084
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.082
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.080
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.080
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.079
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.079
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.079
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.077
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.076
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.076
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.075
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.073
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.073
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.072
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.071
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.070
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.070
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.070
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.070
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.070
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.068
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.068
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.067
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.067
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
18 |
0.066
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.066
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.066
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.066
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.065
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.064
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.064
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.064
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.063
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.062
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.062
|
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.061
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.061
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.060
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.060
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.059
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.059
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.059
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.059
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.059
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.059
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.059
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.059
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.058
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.058
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.057
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.057
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.056
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.056
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.055
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.055
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.055
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.054
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.054
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.054
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.054
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.053
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.052
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.051
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.051
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.050
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.050
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.050
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.050
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.049
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.049
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.049
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.049
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.048
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.048
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.047
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.047
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.047
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.047
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.046
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.046
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
19 |
0.046
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.046
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.046
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.046
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.045
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.045
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.045
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.045
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.044
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.044
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.044
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.043
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.043
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.043
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.043
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.043
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.042
|
|
|
|
protein auto adp ribosylation
|
GO:0070213 |
4 |
0.042
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.042
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.042
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.041
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.041
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.041
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.041
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.041
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.040
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.040
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.040
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.040
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.039
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.039
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.038
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.038
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.038
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.038
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.038
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.037
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.037
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.037
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.037
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.036
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.036
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.036
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.036
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.036
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.036
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.036
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.036
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.036
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.036
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.035
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.035
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.035
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.035
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.035
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.035
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.035
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.035
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.035
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.034
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.034
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.034
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.034
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.034
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.034
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.033
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.033
|
|
|
|
thyroid hormone metabolic process
|
GO:0042403 |
4 |
0.033
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.033
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.032
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.032
|
|
|
|
regulation of protein acetylation
|
GO:1901983 |
25 |
0.032
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.032
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.031
|
|
|
|
androgen biosynthetic process
|
GO:0006702 |
3 |
0.031
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.031
|
|
|
|
head development
|
GO:0060322 |
108 |
0.031
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.031
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.031
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.031
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.031
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.031
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.030
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.030
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.030
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.030
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.030
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.030
|
|
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.029
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.029
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.029
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.029
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.029
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.029
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.029
|
|
|
|
growth
|
GO:0040007 |
202 |
0.029
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.029
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.028
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.028
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.028
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.028
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.028
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.028
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.028
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.028
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.028
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.028
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.028
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.027
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.027
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.027
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.027
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.027
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.027
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.027
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.026
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.026
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.026
|
|
|
|
protein adp ribosylation
|
GO:0006471 |
9 |
0.026
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.026
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.026
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.026
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.026
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.025
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.025
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.025
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.025
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.025
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.025
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.025
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.025
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.024
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.024
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.024
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.024
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.024
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.024
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.024
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.024
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.024
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.024
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.023
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.023
|
|
|
|
positive regulation of vasculogenesis
|
GO:2001214 |
1 |
0.023
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.023
|
|
|
|
aging
|
GO:0007568 |
66 |
0.023
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.023
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.023
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.023
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.023
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.023
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.023
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.023
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.023
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.023
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.022
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.022
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.022
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.022
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.022
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.022
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.022
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.022
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.022
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.022
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.021
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.021
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.021
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.021
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.021
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.021
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.021
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.021
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.021
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.021
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.021
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.021
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.021
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.020
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.020
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.020
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.020
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.020
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.020
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.020
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.020
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.020
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.020
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.020
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.020
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.020
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.020
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.020
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.020
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.019
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.019
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.019
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.019
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.019
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.019
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.019
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.019
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.019
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.019
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.019
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.019
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.019
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.019
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.019
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.019
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.019
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.019
|
|
|
|
system process
|
GO:0003008 |
349 |
0.019
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.019
|
|
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.019
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.019
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.019
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.019
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.019
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.018
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.018
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.018
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.018
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.018
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.018
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.018
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.018
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.018
|
|
|
|
dna templated transcription termination
|
GO:0006353 |
3 |
0.018
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.018
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.018
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.018
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.018
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.018
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.018
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.018
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.018
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.018
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.018
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.018
|
|
|
|
tachykinin receptor signaling pathway
|
GO:0007217 |
3 |
0.018
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.018
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.018
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.018
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.017
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.017
|
|
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.017
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.017
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.017
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.017
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.017
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.017
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.017
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.017
|
|
|
|
adenylate cyclase activating adrenergic receptor signaling pathway
|
GO:0071880 |
3 |
0.017
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.017
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.017
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.017
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.017
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.017
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.017
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.017
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.017
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.017
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.017
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.017
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.017
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.017
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.017
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.017
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.017
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.016
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.016
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.016
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.016
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.016
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.016
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.016
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.016
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.016
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.016
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.016
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.016
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.016
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.016
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.016
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.016
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.015
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.015
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.015
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.015
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.015
|
|
