Homo sapiens

280 known processes

RYR2

ryanodine receptor 2 (cardiac)

(Aliases: ARVC2,VTSIP,ARVD2)

RYR2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic ion transmembrane transport GO:0098660 231 0.875
inorganic cation transmembrane transport GO:0098662 194 0.756
ion transmembrane transport GO:0034220 338 0.690
regulation of ion transmembrane transport GO:0034765 132 0.659
cation transmembrane transport GO:0098655 238 0.648
metal ion transport GO:0030001 272 0.623
transmembrane transport GO:0055085 399 0.555
regulation of ion transport GO:0043269 189 0.513
positive regulation of transport GO:0051050 336 0.484
regulation of transmembrane transport GO:0034762 139 0.438
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.378
chemical homeostasis GO:0048878 306 0.349
cellular homeostasis GO:0019725 196 0.342
cellular response to endogenous stimulus GO:0071495 336 0.326
cation transport GO:0006812 331 0.312
positive regulation of ion transport GO:0043270 87 0.269
regulation of metal ion transport GO:0010959 120 0.268
associative learning GO:0008306 1 0.264
muscle contraction GO:0006936 73 0.245
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.239
cellular potassium ion transport GO:0071804 60 0.231
system process GO:0003008 349 0.231
cellular response to organic cyclic compound GO:0071407 127 0.220
circadian sleep wake cycle GO:0042745 2 0.220
positive regulation of ion transmembrane transport GO:0034767 40 0.206
potassium ion transmembrane transport GO:0071805 60 0.203
circadian sleep wake cycle sleep GO:0050802 2 0.197
cardiac muscle contraction GO:0060048 34 0.193
small gtpase mediated signal transduction GO:0007264 78 0.191
regulation of cellular amino acid metabolic process GO:0006521 6 0.186
response to oxygen containing compound GO:1901700 369 0.185
regulation of potassium ion transmembrane transport GO:1901379 20 0.183
post embryonic development GO:0009791 2 0.182
regulation of transmembrane transporter activity GO:0022898 74 0.180
ras protein signal transduction GO:0007265 73 0.179
cellular chemical homeostasis GO:0055082 180 0.176
amine metabolic process GO:0009308 44 0.171
memory GO:0007613 3 0.167
response to organonitrogen compound GO:0010243 156 0.165
cellular amine metabolic process GO:0044106 41 0.158
regulation of delayed rectifier potassium channel activity GO:1902259 4 0.156
potassium ion transport GO:0006813 62 0.155
cellular response to oxygen containing compound GO:1901701 276 0.152
regulation of locomotion GO:0040012 329 0.148
regulation of transporter activity GO:0032409 82 0.145
monovalent inorganic cation transport GO:0015672 128 0.144
cell adhesion GO:0007155 325 0.142
cellular amino acid metabolic process GO:0006520 116 0.141
negative regulation of smoothened signaling pathway GO:0045879 3 0.136
muscle system process GO:0003012 81 0.134
regulation of epithelial cell differentiation involved in kidney development GO:2000696 4 0.131
anterior posterior axis specification embryo GO:0008595 2 0.126
circadian behavior GO:0048512 2 0.125
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.122
regulation of cellular component biogenesis GO:0044087 281 0.121
regulation of meiotic cell cycle GO:0051445 4 0.120
cellular ketone metabolic process GO:0042180 80 0.119
negative regulation of embryonic development GO:0045992 4 0.118
calcium ion transport GO:0006816 147 0.115
ion homeostasis GO:0050801 230 0.114
tripartite regional subdivision GO:0007351 2 0.114
cellular response to camp GO:0071320 21 0.112
positive regulation of transporter activity GO:0032411 32 0.112
cellular ion homeostasis GO:0006873 168 0.111
cation homeostasis GO:0055080 189 0.108
blastoderm segmentation GO:0007350 2 0.108
negative regulation of multicellular organismal process GO:0051241 317 0.106
regulation of system process GO:0044057 101 0.104
oogenesis GO:0048477 2 0.103
anterior posterior axis specification GO:0009948 2 0.103
regulation of intracellular transport GO:0032386 195 0.102
Mouse
response to camp GO:0051591 25 0.098
regulation of ion transmembrane transporter activity GO:0032412 72 0.097
cellular response to organonitrogen compound GO:0071417 124 0.096
cytoplasmic transport GO:0016482 379 0.093
regulation of cell maturation GO:1903429 3 0.093
striated muscle contraction GO:0006941 52 0.091
cellular response to nitrogen compound GO:1901699 144 0.091
regulation of cation channel activity GO:2001257 33 0.091
Mouse
spermatid development GO:0007286 4 0.091
membrane repolarization GO:0086009 23 0.090
cellular divalent inorganic cation homeostasis GO:0072503 128 0.090
oocyte differentiation GO:0009994 2 0.089
regulation of cellular amine metabolic process GO:0033238 11 0.088
cellular calcium ion homeostasis GO:0006874 117 0.088
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.087
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.087
protein catabolic process GO:0030163 325 0.086
regulation of behavior GO:0050795 82 0.086
neural tube patterning GO:0021532 2 0.084
regulation of cellular component movement GO:0051270 334 0.084
Mouse
regulation of cell migration GO:0030334 289 0.084
cell substrate adhesion GO:0031589 132 0.083
regulation of proteasomal protein catabolic process GO:0061136 87 0.083
calcium ion homeostasis GO:0055074 122 0.083
sleep GO:0030431 2 0.083
mitochondrion organization GO:0007005 156 0.083
regulation of cell motility GO:2000145 299 0.082
segmentation GO:0035282 4 0.082
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.081
cytosolic calcium ion homeostasis GO:0051480 89 0.080
morphogenesis of embryonic epithelium GO:0016331 4 0.080
calcium ion transmembrane transport GO:0070588 76 0.079
regulation of proteolysis GO:0030162 293 0.079
neurological system process GO:0050877 163 0.078
oxidation reduction process GO:0055114 396 0.077
regulation of cell development GO:0060284 161 0.077
positive regulation of synaptic transmission GO:0050806 4 0.076
peptidyl serine phosphorylation GO:0018105 101 0.076
positive regulation of intracellular transport GO:0032388 104 0.075
ribonucleoside triphosphate catabolic process GO:0009203 391 0.074
response to abiotic stimulus GO:0009628 336 0.074
Human Mouse
positive regulation of cytoplasmic transport GO:1903651 82 0.074
response to organic cyclic compound GO:0014070 204 0.073
oocyte maturation GO:0001556 1 0.073
endothelial cell proliferation GO:0001935 65 0.072
regulation of purine nucleotide metabolic process GO:1900542 264 0.072
nucleoside triphosphate catabolic process GO:0009143 394 0.072
regulation of protein localization GO:0032880 296 0.071
protein maturation GO:0051604 233 0.070
cellular response to parathyroid hormone stimulus GO:0071374 2 0.070
cellular macromolecule catabolic process GO:0044265 380 0.069
negative regulation of phosphate metabolic process GO:0045936 267 0.068
negative regulation of catalytic activity GO:0043086 335 0.068
ameboidal type cell migration GO:0001667 135 0.068
spermatid differentiation GO:0048515 4 0.068
positive regulation of protein transport GO:0051222 135 0.067
inorganic anion transmembrane transport GO:0098661 47 0.066
regulation of muscle system process GO:0090257 53 0.066
regulation of membrane repolarization GO:0060306 16 0.066
membrane organization GO:0061024 292 0.065
purine nucleotide catabolic process GO:0006195 405 0.065
heart contraction GO:0060047 62 0.065
protein processing GO:0016485 226 0.064
circulatory system process GO:0003013 113 0.064
signal transduction by phosphorylation GO:0023014 297 0.064
blood circulation GO:0008015 113 0.064
regulation of cardiac muscle contraction GO:0055117 33 0.064
positive regulation of intracellular protein transport GO:0090316 76 0.063
cardiac muscle cell contraction GO:0086003 4 0.063
cell development GO:0048468 328 0.063
actin filament based movement GO:0030048 17 0.063
regulation of cell cycle arrest GO:0071156 36 0.063
purine ribonucleoside metabolic process GO:0046128 437 0.063
single organism cellular localization GO:1902580 332 0.063
purine nucleoside triphosphate metabolic process GO:0009144 412 0.063
epithelial cell migration GO:0010631 119 0.062
protein autophosphorylation GO:0046777 123 0.062
female gamete generation GO:0007292 2 0.062
purine nucleoside triphosphate catabolic process GO:0009146 392 0.062
regulation of nucleoside metabolic process GO:0009118 209 0.062
sequestering of calcium ion GO:0051208 17 0.062
primary neural tube formation GO:0014020 3 0.062
organophosphate catabolic process GO:0046434 430 0.061
regulation of oocyte development GO:0060281 1 0.061
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.060
nucleoside triphosphate metabolic process GO:0009141 422 0.060
regulation of potassium ion transport GO:0043266 24 0.059
secretion GO:0046903 254 0.059
oocyte development GO:0048599 1 0.059
biological adhesion GO:0022610 331 0.058
nervous system development GO:0007399 293 0.058
sequestering of metal ion GO:0051238 24 0.058
regulation of cell differentiation GO:0045595 393 0.058
locomotory behavior GO:0007626 1 0.057
regulation of transferase activity GO:0051338 355 0.057
cell junction organization GO:0034330 79 0.057
nucleoside catabolic process GO:0009164 408 0.057
regulation of cytoplasmic transport GO:1903649 149 0.057
Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.056
regulation of synaptic plasticity GO:0048167 3 0.056
negative regulation of phosphorus metabolic process GO:0010563 267 0.056
ribonucleoside catabolic process GO:0042454 406 0.056
cell cycle arrest GO:0007050 71 0.056
regulation of cellular ketone metabolic process GO:0010565 50 0.055
behavior GO:0007610 112 0.055
negative regulation of meiotic cell cycle GO:0051447 2 0.055
tube closure GO:0060606 3 0.054
regulation of oocyte maturation GO:1900193 1 0.054
purine ribonucleoside catabolic process GO:0046130 398 0.053
regulation of ion homeostasis GO:2000021 73 0.053
positive regulation of nucleotide metabolic process GO:0045981 230 0.053
positive regulation of nucleotide catabolic process GO:0030813 185 0.053
secretion by cell GO:0032940 226 0.052
peptidyl threonine modification GO:0018210 45 0.052
cellular cation homeostasis GO:0030003 163 0.052
protein localization to organelle GO:0033365 280 0.052
purine ribonucleotide catabolic process GO:0009154 404 0.052
regulation of membrane potential GO:0042391 95 0.052
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.052
regulation of protein transport GO:0051223 213 0.052
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.051
proteasomal protein catabolic process GO:0010498 176 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.050
blood vessel morphogenesis GO:0048514 162 0.050
intracellular mrna localization GO:0008298 1 0.049
intracellular protein transport GO:0006886 270 0.049
positive regulation of cell development GO:0010720 92 0.049
endothelial cell migration GO:0043542 86 0.049
regulation of protein catabolic process GO:0042176 155 0.048
negative regulation of cell cycle GO:0045786 193 0.048
divalent inorganic cation transport GO:0072511 158 0.048
small molecule biosynthetic process GO:0044283 157 0.047
glycosyl compound catabolic process GO:1901658 413 0.047
response to hormone GO:0009725 175 0.047
tissue migration GO:0090130 119 0.046
neuromuscular junction development GO:0007528 3 0.046
regulation of cell cycle process GO:0010564 266 0.046
positive regulation of cellular amine metabolic process GO:0033240 7 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
epithelial cell differentiation GO:0030855 141 0.045
vesicle mediated transport GO:0016192 371 0.045
nucleotide catabolic process GO:0009166 408 0.044
single organism membrane organization GO:0044802 268 0.044
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.044
divalent inorganic cation homeostasis GO:0072507 136 0.044
cell cell junction organization GO:0045216 69 0.044
multicellular organismal aging GO:0010259 3 0.044
positive regulation of cell cycle GO:0045787 140 0.044
negative regulation of transport GO:0051051 176 0.044
regulation of secretion by cell GO:1903530 177 0.043
positive regulation of hydrolase activity GO:0051345 331 0.043
ribonucleotide catabolic process GO:0009261 405 0.043
angiogenesis GO:0001525 147 0.043
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.043
positive regulation of catabolic process GO:0009896 310 0.043
regulation of purine nucleotide catabolic process GO:0033121 205 0.042
protein ubiquitination GO:0016567 314 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.042
positive regulation of developmental process GO:0051094 314 0.042
guanosine containing compound metabolic process GO:1901068 244 0.042
response to organophosphorus GO:0046683 41 0.042
microtubule based process GO:0007017 210 0.041
positive regulation of cellular component organization GO:0051130 376 0.041
anion transport GO:0006820 161 0.041
membrane hyperpolarization GO:0060081 1 0.041
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.041
carboxylic acid biosynthetic process GO:0046394 97 0.040
purine containing compound catabolic process GO:0072523 411 0.040
regulation of cell adhesion GO:0030155 166 0.040
actin filament based process GO:0030029 224 0.040
purine nucleoside catabolic process GO:0006152 398 0.040
negative regulation of protein metabolic process GO:0051248 391 0.040
cellular protein catabolic process GO:0044257 261 0.039
regulation of establishment of protein localization GO:0070201 242 0.039
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.039
regulation of multi organism process GO:0043900 157 0.039
circulatory system development GO:0072359 262 0.039
Mouse
regulation of cellular protein catabolic process GO:1903362 96 0.038
positive regulation of nucleoside metabolic process GO:0045979 186 0.038
positive regulation of cellular catabolic process GO:0031331 284 0.037
negative regulation of programmed cell death GO:0043069 321 0.037
nucleoside phosphate biosynthetic process GO:1901293 109 0.037
regulation of calcium ion transmembrane transport GO:1903169 28 0.037
nuclear export GO:0051168 69 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.037
vasculature development GO:0001944 181 0.036
nucleocytoplasmic transport GO:0006913 176 0.036
inner ear morphogenesis GO:0042472 4 0.036
positive regulation of cell differentiation GO:0045597 211 0.036
response to parathyroid hormone GO:0071107 3 0.036
regulation of cell junction assembly GO:1901888 29 0.036
nitrogen compound transport GO:0071705 191 0.036
regulation of kinase activity GO:0043549 314 0.036
rho protein signal transduction GO:0007266 26 0.036
regulation of cell cycle GO:0051726 393 0.035
guanosine containing compound catabolic process GO:1901069 239 0.035
ribonucleoside triphosphate metabolic process GO:0009199 412 0.035
regulation of homeostatic process GO:0032844 121 0.035
regulation of neuronal synaptic plasticity GO:0048168 1 0.035
chloride transport GO:0006821 41 0.035
cardiovascular system development GO:0072358 262 0.034
Mouse
negative regulation of phosphorylation GO:0042326 174 0.034
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.034
rhythmic behavior GO:0007622 2 0.034
urogenital system development GO:0001655 65 0.034
second messenger mediated signaling GO:0019932 78 0.034
peptidyl threonine phosphorylation GO:0018107 41 0.034
tube development GO:0035295 125 0.034
Mouse
cellular metal ion homeostasis GO:0006875 146 0.034
nuclear transport GO:0051169 179 0.033
apoptotic signaling pathway GO:0097190 268 0.033
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.033
regulation of intracellular protein transport GO:0033157 123 0.033
cellular component morphogenesis GO:0032989 314 0.033
peptidyl serine modification GO:0018209 106 0.033
regulation of nucleotide catabolic process GO:0030811 205 0.032
response to carbohydrate GO:0009743 21 0.032
regulation of response to external stimulus GO:0032101 222 0.032
regulation of blood circulation GO:1903522 59 0.032
regulation of actin filament based process GO:0032970 141 0.032
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.032
metal ion homeostasis GO:0055065 169 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.032
sodium ion transmembrane transport GO:0035725 59 0.031
cyclic purine nucleotide metabolic process GO:0052652 60 0.031
regulation of cyclase activity GO:0031279 19 0.031
protein modification by small protein conjugation GO:0032446 342 0.031
regulation of protein kinase activity GO:0045859 289 0.031
positive regulation of cell death GO:0010942 263 0.030
cellular glucose homeostasis GO:0001678 11 0.030
negative regulation of developmental process GO:0051093 247 0.030
negative regulation of homeostatic process GO:0032845 59 0.030
organic acid biosynthetic process GO:0016053 97 0.030
regulation of protein processing GO:0070613 150 0.030
establishment of protein localization to organelle GO:0072594 172 0.029
regulation of nervous system development GO:0051960 88 0.029
taxis GO:0042330 157 0.029
blood vessel development GO:0001568 172 0.029
carbohydrate derivative biosynthetic process GO:1901137 207 0.029
ribonucleotide biosynthetic process GO:0009260 81 0.029
cyclic nucleotide metabolic process GO:0009187 82 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
formation of primary germ layer GO:0001704 42 0.028
calcium ion transport into cytosol GO:0060402 48 0.028
positive regulation of cell cycle arrest GO:0071158 23 0.028
glucose homeostasis GO:0042593 31 0.028
regulation of nucleocytoplasmic transport GO:0046822 98 0.028
cellular macromolecular complex assembly GO:0034622 324 0.028
cell cell signaling GO:0007267 155 0.028
Mouse
gtp metabolic process GO:0046039 239 0.028
response to biotic stimulus GO:0009607 276 0.028
regulation of generation of precursor metabolites and energy GO:0043467 27 0.028
regulation of secretion GO:0051046 194 0.027
immune system development GO:0002520 195 0.027
microtubule cytoskeleton organization GO:0000226 176 0.027
generation of precursor metabolites and energy GO:0006091 68 0.027
digestive system development GO:0055123 75 0.027
purine containing compound biosynthetic process GO:0072522 88 0.027
endomembrane system organization GO:0010256 196 0.027
positive regulation of cell cycle process GO:0090068 106 0.027
protein export from nucleus GO:0006611 29 0.026
ossification GO:0001503 121 0.026
positive regulation of cation channel activity GO:2001259 16 0.026
Mouse
lipid biosynthetic process GO:0008610 177 0.026
regulation of protein maturation GO:1903317 150 0.026
endocytosis GO:0006897 159 0.026
adult locomotory behavior GO:0008344 1 0.026
cellular response to monosaccharide stimulus GO:0071326 10 0.026
immune response GO:0006955 307 0.026
regulation of ossification GO:0030278 58 0.026
dephosphorylation GO:0016311 209 0.026
neuron development GO:0048666 113 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
regeneration GO:0031099 4 0.025
cellular response to hormone stimulus GO:0032870 125 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
negative regulation of cellular amine metabolic process GO:0033239 3 0.025
generation of neurons GO:0048699 152 0.025
purine ribonucleotide biosynthetic process GO:0009152 79 0.025
divalent metal ion transport GO:0070838 152 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
organ morphogenesis GO:0009887 147 0.025
Mouse
regulation of heart rate GO:0002027 38 0.025
heart process GO:0003015 62 0.024
cell morphogenesis GO:0000902 296 0.024
nucleotide biosynthetic process GO:0009165 109 0.024
digestive tract development GO:0048565 75 0.024
enzyme linked receptor protein signaling pathway GO:0007167 303 0.024
Mouse
regulation of gtpase activity GO:0043087 180 0.024
positive regulation of ras gtpase activity GO:0032320 117 0.024
regulation of protein serine threonine kinase activity GO:0071900 179 0.024
regulation of nucleotide biosynthetic process GO:0030808 50 0.024
transmission of nerve impulse GO:0019226 11 0.024
regulation of sequestering of calcium ion GO:0051282 41 0.023
negative regulation of sequestering of calcium ion GO:0051283 41 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.023
response to external biotic stimulus GO:0043207 261 0.023
purine nucleoside monophosphate catabolic process GO:0009128 158 0.023
epithelium development GO:0060429 227 0.023
Mouse
positive regulation of homeostatic process GO:0032846 47 0.023
amide transport GO:0042886 76 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
peripheral nervous system development GO:0007422 2 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.023
negative regulation of secretion by cell GO:1903531 52 0.023
positive regulation of potassium ion transmembrane transport GO:1901381 12 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
neurogenesis GO:0022008 169 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
regulation of calcium ion transport GO:0051924 79 0.022
sodium ion transport GO:0006814 61 0.022
cyclic nucleotide biosynthetic process GO:0009190 61 0.022
negative regulation of cell death GO:0060548 345 0.022
regulation of immune response GO:0050776 201 0.022
osteoblast differentiation GO:0001649 92 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.021
hard palate development GO:0060022 1 0.021
purine nucleotide biosynthetic process GO:0006164 84 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
regulation of striated muscle contraction GO:0006942 37 0.021
spinal cord development GO:0021510 4 0.021
epithelium migration GO:0090132 119 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
ribonucleoside monophosphate catabolic process GO:0009158 158 0.021
positive regulation of transferase activity GO:0051347 227 0.021
cell projection organization GO:0030030 252 0.021
multicellular organismal signaling GO:0035637 34 0.021
Mouse
peptide hormone secretion GO:0030072 50 0.021
single organism cell adhesion GO:0098602 179 0.021
organ formation GO:0048645 3 0.021
neural tube formation GO:0001841 3 0.021
negative regulation of protein modification process GO:0031400 200 0.021
positive regulation of potassium ion transport GO:0043268 15 0.021
negative regulation of hydrolase activity GO:0051346 182 0.020
regulation of transmission of nerve impulse GO:0051969 2 0.020
response to hexose GO:0009746 20 0.020
gtp catabolic process GO:0006184 237 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
hemopoiesis GO:0030097 180 0.020
growth GO:0040007 202 0.020
positive regulation of vasodilation GO:0045909 4 0.020
lipid metabolic process GO:0006629 381 0.020
vasodilation GO:0042311 4 0.020
positive regulation of gtpase activity GO:0043547 166 0.020
regulation of heart contraction GO:0008016 50 0.020
peptide transport GO:0015833 74 0.020
atp metabolic process GO:0046034 176 0.020
rna processing GO:0006396 255 0.020
release of sequestered calcium ion into cytosol GO:0051209 41 0.020
response to other organism GO:0051707 261 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
regulation of hormone levels GO:0010817 125 0.020
cytokine production GO:0001816 247 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
response to inorganic substance GO:0010035 127 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
regulation of cytoskeleton organization GO:0051493 177 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
single organismal cell cell adhesion GO:0016337 148 0.019
establishment of protein localization to membrane GO:0090150 121 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
response to lithium ion GO:0010226 2 0.019
mitotic cell cycle process GO:1903047 286 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
neural tube closure GO:0001843 3 0.019
actin mediated cell contraction GO:0070252 12 0.019
limbic system development GO:0021761 3 0.019
motor neuron axon guidance GO:0008045 2 0.019
positive regulation of immune system process GO:0002684 283 0.019
cell projection assembly GO:0030031 126 0.019
negative regulation of ion transmembrane transport GO:0034766 26 0.019
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.019
long term memory GO:0007616 2 0.019
response to cytokine GO:0034097 232 0.019
hormone transport GO:0009914 68 0.019
positive regulation of organelle organization GO:0010638 195 0.019
renal system development GO:0072001 63 0.019
mitotic cell cycle GO:0000278 326 0.019
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.019
carbohydrate homeostasis GO:0033500 31 0.019
determination of adult lifespan GO:0008340 2 0.018
cellular amino acid biosynthetic process GO:0008652 30 0.018
positive regulation of axon extension GO:0045773 4 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
synaptic transmission GO:0007268 61 0.018
neuron fate commitment GO:0048663 2 0.018
cell fate determination GO:0001709 3 0.018
response to glucose GO:0009749 19 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
organic anion transport GO:0015711 103 0.018
regulation of circadian sleep wake cycle GO:0042749 2 0.018
negative regulation of gliogenesis GO:0014014 3 0.018
cell growth GO:0016049 160 0.018
stem cell division GO:0017145 2 0.018
negative regulation of transferase activity GO:0051348 124 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
atp catabolic process GO:0006200 157 0.018
synaptic vesicle endocytosis GO:0048488 2 0.017
positive regulation of gtp catabolic process GO:0033126 166 0.017
kidney morphogenesis GO:0060993 19 0.017
anion transmembrane transport GO:0098656 76 0.017
protein localization to membrane GO:0072657 160 0.017
positive regulation of camp biosynthetic process GO:0030819 35 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.017
negative regulation of transmembrane transport GO:0034763 29 0.017
negative regulation of cell proliferation GO:0008285 228 0.017

RYR2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.030
nervous system disease DOID:863 431 0.030
respiratory system disease DOID:1579 14 0.029
lower respiratory tract disease DOID:0050161 13 0.029
cancer DOID:162 167 0.029
disease of cellular proliferation DOID:14566 174 0.029
cardiovascular system disease DOID:1287 106 0.026
organ system cancer DOID:0050686 164 0.025
disease of metabolism DOID:0014667 295 0.023
musculoskeletal system disease DOID:17 223 0.021
inherited metabolic disorder DOID:655 242 0.019
sensory system disease DOID:0050155 203 0.018
myopathy DOID:423 104 0.018
muscular disease DOID:0080000 114 0.018
muscle tissue disease DOID:66 113 0.018