Homo sapiens

17 known processes

SAT1

spermidine/spermine N1-acetyltransferase 1

(Aliases: DC21,SSAT,KFSD,SSAT-1,KFSDX,SAT)

SAT1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
store operated calcium entry GO:0002115 3 0.711
circulatory system development GO:0072359 262 0.508
regulation of endopeptidase activity GO:0052548 170 0.395
protein maturation GO:0051604 233 0.384
negative regulation of protein maturation GO:1903318 142 0.349
cellular biogenic amine metabolic process GO:0006576 34 0.342
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.321
defense response GO:0006952 315 0.298
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.274
response to radiation GO:0009314 151 0.247
basement membrane organization GO:0071711 3 0.243
regulation of peptidase activity GO:0052547 180 0.234
response to external biotic stimulus GO:0043207 261 0.231
negative regulation of peptidase activity GO:0010466 91 0.230
protein processing GO:0016485 226 0.230
polyamine metabolic process GO:0006595 4 0.222
Human
response to abiotic stimulus GO:0009628 336 0.217
ribonucleoside catabolic process GO:0042454 406 0.195
response to biotic stimulus GO:0009607 276 0.179
negative regulation of catalytic activity GO:0043086 335 0.173
ribonucleotide catabolic process GO:0009261 405 0.166
regulation of metal ion transport GO:0010959 120 0.162
chromosome segregation GO:0007059 114 0.157
spermidine metabolic process GO:0008216 3 0.155
Human
apoptotic signaling pathway GO:0097190 268 0.154
multicellular organismal aging GO:0010259 3 0.154
response to other organism GO:0051707 261 0.153
regulation of protein maturation GO:1903317 150 0.152
calcium ion transport GO:0006816 147 0.149
determination of adult lifespan GO:0008340 2 0.149
cellular response to dna damage stimulus GO:0006974 379 0.148
regulation of apoptotic signaling pathway GO:2001233 175 0.140
immune response GO:0006955 307 0.140
putrescine metabolic process GO:0009445 2 0.139
Human
regulation of reactive oxygen species metabolic process GO:2000377 41 0.139
post embryonic development GO:0009791 2 0.130
negative regulation of protein processing GO:0010955 142 0.126
purine containing compound catabolic process GO:0072523 411 0.119
cellular amino acid metabolic process GO:0006520 116 0.117
cellular amine metabolic process GO:0044106 41 0.114
Human
blood vessel morphogenesis GO:0048514 162 0.112
response to oxygen containing compound GO:1901700 369 0.109
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.106
response to bacterium GO:0009617 144 0.103
regulation of ion transport GO:0043269 189 0.101
response to reactive oxygen species GO:0000302 61 0.098
cation transport GO:0006812 331 0.097
vasculature development GO:0001944 181 0.096
positive regulation of transport GO:0051050 336 0.096
amine metabolic process GO:0009308 44 0.090
Human
positive regulation of catabolic process GO:0009896 310 0.090
response to molecule of bacterial origin GO:0002237 82 0.086
cellular response to lipid GO:0071396 127 0.083
cellular response to lipopolysaccharide GO:0071222 57 0.081
negative regulation of apoptotic signaling pathway GO:2001234 97 0.079
positive regulation of apoptotic process GO:0043065 246 0.079
negative regulation of hydrolase activity GO:0051346 182 0.078
negative regulation of cell differentiation GO:0045596 171 0.077
protein oligomerization GO:0051259 173 0.077
cell type specific apoptotic process GO:0097285 125 0.077
locomotory behavior GO:0007626 1 0.076
cellular response to abiotic stimulus GO:0071214 117 0.075
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.075
positive regulation of immune response GO:0050778 159 0.074
regulation of nucleoside metabolic process GO:0009118 209 0.073
regulation of proteolysis GO:0030162 293 0.072
purine nucleoside triphosphate catabolic process GO:0009146 392 0.069
divalent inorganic cation transport GO:0072511 158 0.069
hemopoiesis GO:0030097 180 0.067
nucleoside catabolic process GO:0009164 408 0.067
ras protein signal transduction GO:0007265 73 0.067
glycosyl compound catabolic process GO:1901658 413 0.067
purine nucleoside triphosphate metabolic process GO:0009144 412 0.066
regulation of calcium ion transport GO:0051924 79 0.066
cellular response to radiation GO:0071478 65 0.063
neuromuscular junction development GO:0007528 3 0.061
vasodilation GO:0042311 4 0.060
nervous system development GO:0007399 293 0.060
response to cytokine GO:0034097 232 0.060
response to oxidative stress GO:0006979 121 0.059
detection of chemical stimulus GO:0009593 55 0.059
organophosphate catabolic process GO:0046434 430 0.058
cardiovascular system development GO:0072358 262 0.058
cellular response to oxygen containing compound GO:1901701 276 0.058
female gamete generation GO:0007292 2 0.058
epithelium development GO:0060429 227 0.057
negative regulation of cell proliferation GO:0008285 228 0.057
regulation of cysteine type endopeptidase activity GO:2000116 127 0.056
cellular response to oxidative stress GO:0034599 85 0.056
metal ion homeostasis GO:0055065 169 0.056
gtp metabolic process GO:0046039 239 0.055
hematopoietic or lymphoid organ development GO:0048534 186 0.053
negative regulation of endopeptidase activity GO:0010951 84 0.053
response to wounding GO:0009611 168 0.053
purine ribonucleoside metabolic process GO:0046128 437 0.053
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.052
positive regulation of programmed cell death GO:0043068 249 0.052
cellular modified amino acid metabolic process GO:0006575 64 0.052
purine ribonucleotide catabolic process GO:0009154 404 0.052
protein catabolic process GO:0030163 325 0.052
regulation of protein processing GO:0070613 150 0.051
response to metal ion GO:0010038 84 0.051
monocarboxylic acid metabolic process GO:0032787 185 0.051
negative regulation of protein metabolic process GO:0051248 391 0.050
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.050
regulation of response to external stimulus GO:0032101 222 0.050
nucleoside phosphate catabolic process GO:1901292 412 0.049
ribonucleoside triphosphate metabolic process GO:0009199 412 0.049
cellular macromolecule catabolic process GO:0044265 380 0.048
regulation of cytokine production GO:0001817 232 0.047
cellular ion homeostasis GO:0006873 168 0.047
positive regulation of cell death GO:0010942 263 0.046
cellular response to molecule of bacterial origin GO:0071219 62 0.046
response to inorganic substance GO:0010035 127 0.046
nucleoside triphosphate catabolic process GO:0009143 394 0.046
regulation of cellular response to stress GO:0080135 244 0.046
protein homooligomerization GO:0051260 100 0.046
negative regulation of proteolysis GO:0045861 132 0.045
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.045
chemical homeostasis GO:0048878 306 0.042
spermine metabolic process GO:0008215 3 0.042
Human
autophagy GO:0006914 88 0.041
response to lipid GO:0033993 206 0.041
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.041
innate immune response GO:0045087 178 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
nucleoside triphosphate metabolic process GO:0009141 422 0.040
apoptotic mitochondrial changes GO:0008637 57 0.039
protein modification by small protein conjugation GO:0032446 342 0.039
defense response to other organism GO:0098542 129 0.039
adaptive immune response GO:0002250 49 0.037
response to thyroid hormone GO:0097066 9 0.037
zymogen activation GO:0031638 70 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
ion homeostasis GO:0050801 230 0.036
rhythmic behavior GO:0007622 2 0.036
biological adhesion GO:0022610 331 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.035
cellular cation homeostasis GO:0030003 163 0.035
cellular response to organic cyclic compound GO:0071407 127 0.035
activation of cysteine type endopeptidase activity GO:0097202 57 0.035
inflammatory response GO:0006954 79 0.034
negative regulation of cell death GO:0060548 345 0.033
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.033
negative regulation of developmental process GO:0051093 247 0.033
reactive nitrogen species metabolic process GO:2001057 3 0.033
oxygen homeostasis GO:0032364 4 0.033
regulation of purine nucleotide metabolic process GO:1900542 264 0.033
metal ion transport GO:0030001 272 0.033
negative regulation of apoptotic process GO:0043066 316 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.032
nucleotide catabolic process GO:0009166 408 0.032
response to ionizing radiation GO:0010212 65 0.032
regulation of gtpase activity GO:0043087 180 0.031
negative regulation of intracellular signal transduction GO:1902532 183 0.031
regulation of anatomical structure morphogenesis GO:0022603 286 0.031
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.031
epithelium migration GO:0090132 119 0.030
maintenance of location GO:0051235 112 0.030
acute inflammatory response GO:0002526 21 0.030
response to oxygen levels GO:0070482 100 0.030
interspecies interaction between organisms GO:0044419 156 0.029
regulation of secretion GO:0051046 194 0.029
response to organic cyclic compound GO:0014070 204 0.029
regulation of angiogenesis GO:0045765 92 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
positive regulation of immune system process GO:0002684 283 0.029
reactive oxygen species metabolic process GO:0072593 75 0.029
myeloid cell differentiation GO:0030099 117 0.028
protein import GO:0017038 130 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
intrinsic apoptotic signaling pathway GO:0097193 127 0.028
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.027
response to mechanical stimulus GO:0009612 51 0.027
positive regulation of protein catabolic process GO:0045732 75 0.027
regulation of protein catabolic process GO:0042176 155 0.027
regulation of tube size GO:0035150 18 0.027
regulation of response to biotic stimulus GO:0002831 55 0.027
hemoglobin biosynthetic process GO:0042541 3 0.026
regulation of leukocyte mediated immunity GO:0002703 38 0.026
response to drug GO:0042493 81 0.026
cell adhesion GO:0007155 325 0.026
regulation of defense response GO:0031347 154 0.025
oogenesis GO:0048477 2 0.025
cellular response to biotic stimulus GO:0071216 71 0.024
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.024
trophectodermal cell differentiation GO:0001829 3 0.024
regeneration GO:0031099 4 0.024
positive regulation of myeloid cell differentiation GO:0045639 39 0.023
response to hypoxia GO:0001666 96 0.023
mitochondrial membrane organization GO:0007006 40 0.023
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.023
negative regulation of thymocyte apoptotic process GO:0070244 1 0.023
rna interference GO:0016246 4 0.023
neuron development GO:0048666 113 0.022
neurological system process GO:0050877 163 0.022
response to lipopolysaccharide GO:0032496 70 0.022
detection of stimulus GO:0051606 85 0.022
embryonic hemopoiesis GO:0035162 4 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
regulation of vasculature development GO:1901342 97 0.021
cation homeostasis GO:0055080 189 0.021
single organism reproductive process GO:0044702 98 0.021
generation of precursor metabolites and energy GO:0006091 68 0.021
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 3 0.021
cell morphogenesis involved in differentiation GO:0000904 144 0.021
transition metal ion homeostasis GO:0055076 31 0.021
cellular component morphogenesis GO:0032989 314 0.020
blood vessel development GO:0001568 172 0.020
meiotic chromosome segregation GO:0045132 4 0.020
chromatin organization GO:0006325 351 0.020
protein tetramerization GO:0051262 47 0.020
regulation of anatomical structure size GO:0090066 101 0.020
fibroblast proliferation GO:0048144 33 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
negative regulation of erythrocyte differentiation GO:0045647 3 0.019
response to light stimulus GO:0009416 87 0.019
cytoplasmic transport GO:0016482 379 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
cell projection organization GO:0030030 252 0.019
response to tumor necrosis factor GO:0034612 76 0.019
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
positive regulation of peptidase activity GO:0010952 88 0.018
positive regulation of hormone biosynthetic process GO:0046886 4 0.018
cellular component disassembly GO:0022411 92 0.018
protein localization to organelle GO:0033365 280 0.018
vascular process in circulatory system GO:0003018 29 0.018
regulation of synaptic plasticity GO:0048167 3 0.018
negative regulation of t cell apoptotic process GO:0070233 4 0.018
response to transition metal nanoparticle GO:1990267 29 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.017
regulation of cell differentiation GO:0045595 393 0.017
muscle cell development GO:0055001 29 0.017
carbohydrate metabolic process GO:0005975 207 0.017
regulation of oxidative stress induced cell death GO:1903201 24 0.017
cellular chemical homeostasis GO:0055082 180 0.017
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.017
cell activation GO:0001775 213 0.017
hemoglobin metabolic process GO:0020027 3 0.017
circulatory system process GO:0003013 113 0.017
wound healing GO:0042060 115 0.017
activation of immune response GO:0002253 114 0.017
cellular protein catabolic process GO:0044257 261 0.016
system process GO:0003008 349 0.016
regulation of ion transmembrane transport GO:0034765 132 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
regulation of cell division GO:0051302 116 0.016
multi organism metabolic process GO:0044033 41 0.016
wnt signaling pathway GO:0016055 156 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
mitochondrion organization GO:0007005 156 0.016
positive regulation of endopeptidase activity GO:0010950 84 0.016
oxidation reduction process GO:0055114 396 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.016
divalent metal ion transport GO:0070838 152 0.015
regulation of inflammatory response GO:0050727 46 0.015
regulation of response to oxidative stress GO:1902882 26 0.015
positive regulation of proteolysis GO:0045862 142 0.015
endothelial cell migration GO:0043542 86 0.015
chromatin modification GO:0016568 298 0.015
organ morphogenesis GO:0009887 147 0.015
rhythmic process GO:0048511 31 0.015
hormone metabolic process GO:0042445 61 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
cell development GO:0048468 328 0.015
primary neural tube formation GO:0014020 3 0.015
negative regulation of cell cycle GO:0045786 193 0.015
cell substrate adhesion GO:0031589 132 0.015
spermatid development GO:0007286 4 0.015
leukocyte migration GO:0050900 107 0.015
response to nitrogen compound GO:1901698 184 0.015
cellular response to reactive oxygen species GO:0034614 50 0.014
positive regulation of secretion GO:0051047 116 0.014
regulation of blood pressure GO:0008217 30 0.014
intracellular protein transport GO:0006886 270 0.014
gas homeostasis GO:0033483 4 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
positive regulation of developmental process GO:0051094 314 0.014
neuron death GO:0070997 65 0.013
regulation of transferase activity GO:0051338 355 0.013
neuron differentiation GO:0030182 138 0.013
negative regulation of fibroblast proliferation GO:0048147 12 0.013
negative regulation of blood pressure GO:0045776 3 0.013
tissue regeneration GO:0042246 3 0.013
embryonic placenta development GO:0001892 1 0.013
multi organism cellular process GO:0044764 156 0.013
regulation of cell migration GO:0030334 289 0.013
reproductive process GO:0022414 106 0.013
positive regulation of ion transport GO:0043270 87 0.013
response to interferon gamma GO:0034341 39 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
mitotic cell cycle GO:0000278 326 0.013
negative regulation of protein modification process GO:0031400 200 0.013
response to virus GO:0009615 126 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 3 0.012
associative learning GO:0008306 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
spermatid differentiation GO:0048515 4 0.012
reproductive system development GO:0061458 56 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
cytokine production GO:0001816 247 0.012
regulation of cellular response to oxidative stress GO:1900407 26 0.012
regulation of homeostatic process GO:0032844 121 0.012
atp metabolic process GO:0046034 176 0.012
regulation of cell development GO:0060284 161 0.012
nitrogen compound transport GO:0071705 191 0.012
cell morphogenesis GO:0000902 296 0.012
epithelial cell differentiation GO:0030855 141 0.012
heart development GO:0007507 95 0.012
negative regulation of synaptic transmission GO:0050805 2 0.012
endomembrane system organization GO:0010256 196 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
cell projection morphogenesis GO:0048858 129 0.012
gtp catabolic process GO:0006184 237 0.012
regulation of viral process GO:0050792 103 0.012
regulation of dna metabolic process GO:0051052 153 0.012
cellular response to light stimulus GO:0071482 34 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.011
organelle fission GO:0048285 149 0.011
regulation of protein secretion GO:0050708 86 0.011
regulation of leukocyte proliferation GO:0070663 67 0.011
negative regulation of blood vessel morphogenesis GO:2000181 41 0.011
sodium ion transport GO:0006814 61 0.011
organic acid biosynthetic process GO:0016053 97 0.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.011
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.011
epithelial cell migration GO:0010631 119 0.011
cellular homeostasis GO:0019725 196 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
cellular response to external stimulus GO:0071496 111 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
sequestering of metal ion GO:0051238 24 0.011
response to activity GO:0014823 0 0.011
single organism membrane organization GO:0044802 268 0.011
transition metal ion transport GO:0000041 23 0.011
positive regulation of innate immune response GO:0045089 79 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of protein localization GO:0032880 296 0.011
protein targeting GO:0006605 187 0.011
regulation of fibroblast proliferation GO:0048145 32 0.010
receptor metabolic process GO:0043112 81 0.010
regulation of multi organism process GO:0043900 157 0.010
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
cell growth GO:0016049 160 0.010
cellular response to mechanical stimulus GO:0071260 39 0.010
regulation of cell cycle GO:0051726 393 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010

SAT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
organ system cancer DOID:0050686 164 0.011