Homo sapiens

0 known processes

SAV1

salvador homolog 1 (Drosophila)

(Aliases: WWP4,SAV,WW45)

SAV1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hippo signaling GO:0035329 20 0.959
Mouse
embryonic epithelial tube formation GO:0001838 4 0.611
morphogenesis of embryonic epithelium GO:0016331 4 0.587
neural tube formation GO:0001841 3 0.581
regulation of cell cycle arrest GO:0071156 36 0.458
embryonic placenta development GO:0001892 1 0.305
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.274
cellular amino acid metabolic process GO:0006520 116 0.220
negative regulation of wnt signaling pathway GO:0030178 69 0.200
regulation of canonical wnt signaling pathway GO:0060828 88 0.199
positive regulation of fat cell differentiation GO:0045600 12 0.191
Mouse
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.183
cellular response to dna damage stimulus GO:0006974 379 0.176
regulation of cell cycle GO:0051726 393 0.176
negative regulation of glial cell proliferation GO:0060253 2 0.150
growth GO:0040007 202 0.147
Mouse Fly
amine metabolic process GO:0009308 44 0.139
multicellular organismal aging GO:0010259 3 0.139
determination of adult lifespan GO:0008340 2 0.138
regulation of protein localization GO:0032880 296 0.128
protein autophosphorylation GO:0046777 123 0.117
regulation of wnt signaling pathway GO:0030111 123 0.114
positive regulation of phosphorylation GO:0042327 394 0.107
neuromuscular junction development GO:0007528 3 0.105
endocardium development GO:0003157 2 0.098
small gtpase mediated signal transduction GO:0007264 78 0.097
cell division GO:0051301 168 0.094
regulation of cellular amino acid metabolic process GO:0006521 6 0.091
regulation of growth GO:0040008 165 0.088
Mouse Fly
regulation of cell cycle process GO:0010564 266 0.088
system process GO:0003008 349 0.087
intraciliary transport GO:0042073 7 0.086
canonical wnt signaling pathway GO:0060070 116 0.085
cellular amine metabolic process GO:0044106 41 0.084
signal transduction by phosphorylation GO:0023014 297 0.082
regulation of mapk cascade GO:0043408 262 0.080
regulation of cell motility GO:2000145 299 0.077
response to ionizing radiation GO:0010212 65 0.076
Fly
ras protein signal transduction GO:0007265 73 0.074
behavioral response to ethanol GO:0048149 2 0.073
positive regulation of cell death GO:0010942 263 0.071
Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.071
embryonic hemopoiesis GO:0035162 4 0.070
regulation of cellular amine metabolic process GO:0033238 11 0.069
rna processing GO:0006396 255 0.066
post embryonic development GO:0009791 2 0.064
stress activated protein kinase signaling cascade GO:0031098 94 0.062
endoplasmic reticulum organization GO:0007029 20 0.062
mapk cascade GO:0000165 288 0.060
tube development GO:0035295 125 0.060
Mouse Fly
regulation of fat cell differentiation GO:0045598 23 0.060
Mouse
regulation of system process GO:0044057 101 0.057
rho protein signal transduction GO:0007266 26 0.055
regulation of jnk cascade GO:0046328 73 0.055
positive regulation of mapk cascade GO:0043410 190 0.055
protein localization to endoplasmic reticulum GO:0070972 19 0.054
epithelial cell differentiation GO:0030855 141 0.053
Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.052
epithelium development GO:0060429 227 0.052
Mouse Fly
wnt signaling pathway GO:0016055 156 0.052
memory GO:0007613 3 0.052
intracellular protein transport GO:0006886 270 0.050
anatomical structure formation involved in morphogenesis GO:0048646 284 0.050
regulation of cellular component biogenesis GO:0044087 281 0.049
posttranscriptional regulation of gene expression GO:0010608 213 0.049
Mouse
segmentation GO:0035282 4 0.049
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.049
cellular component morphogenesis GO:0032989 314 0.048
Fly
cell development GO:0048468 328 0.048
Mouse Fly
peptidyl serine phosphorylation GO:0018105 101 0.047
regulation of locomotion GO:0040012 329 0.047
positive regulation of programmed cell death GO:0043068 249 0.047
Mouse Fly
cell projection organization GO:0030030 252 0.046
Fly
positive regulation of apoptotic process GO:0043065 246 0.046
Mouse Fly
regulation of meiosis GO:0040020 3 0.046
positive regulation of protein kinase b signaling GO:0051897 42 0.045
central nervous system development GO:0007417 123 0.045
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.045
Mouse
blood circulation GO:0008015 113 0.044
tissue morphogenesis GO:0048729 96 0.043
blastoderm segmentation GO:0007350 2 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
negative regulation of developmental process GO:0051093 247 0.042
Mouse
biological adhesion GO:0022610 331 0.040
regulation of meiotic cell cycle GO:0051445 4 0.039
cellular ketone metabolic process GO:0042180 80 0.039
positive regulation of jnk cascade GO:0046330 52 0.039
regulation of cell development GO:0060284 161 0.038
Mouse Fly
maintenance of location GO:0051235 112 0.038
cell proliferation in forebrain GO:0021846 1 0.038
cardiac muscle cell contraction GO:0086003 4 0.037
regulation of protein stability GO:0031647 87 0.037
Mouse
gtp catabolic process GO:0006184 237 0.037
negative regulation of cell proliferation GO:0008285 228 0.037
Mouse Fly
cation transmembrane transport GO:0098655 238 0.036
organelle fission GO:0048285 149 0.036
sodium ion transport GO:0006814 61 0.036
protein stabilization GO:0050821 64 0.035
Mouse
fat cell differentiation GO:0045444 32 0.035
Mouse
regulation of cellular response to stress GO:0080135 244 0.034
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
actin cytoskeleton organization GO:0030036 207 0.034
negative regulation of growth GO:0045926 97 0.034
Mouse
regulation of neurogenesis GO:0050767 82 0.034
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
nervous system development GO:0007399 293 0.033
Fly
peptidyl serine modification GO:0018209 106 0.033
cellular macromolecule catabolic process GO:0044265 380 0.033
adult locomotory behavior GO:0008344 1 0.033
regulation of binding GO:0051098 111 0.032
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.032
positive regulation of intracellular protein transport GO:0090316 76 0.032
morphogenesis of an epithelium GO:0002009 60 0.032
female gamete generation GO:0007292 2 0.031
protein modification by small protein conjugation GO:0032446 342 0.031
inorganic ion transmembrane transport GO:0098660 231 0.030
negative regulation of cell cycle process GO:0010948 121 0.030
actin mediated cell contraction GO:0070252 12 0.030
positive regulation of stress activated mapk cascade GO:0032874 60 0.029
response to nitrogen compound GO:1901698 184 0.029
regulation of protein binding GO:0043393 66 0.029
regulation of cell morphogenesis GO:0022604 153 0.029
Fly
regulation of cellular component movement GO:0051270 334 0.028
tube morphogenesis GO:0035239 95 0.028
regulation of intracellular protein transport GO:0033157 123 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.028
Mouse
endomembrane system organization GO:0010256 196 0.028
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.028
regulation of ion transmembrane transport GO:0034765 132 0.027
positive regulation of protein binding GO:0032092 24 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.027
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.027
circulatory system development GO:0072359 262 0.027
Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.027
positive regulation of protein transport GO:0051222 135 0.027
positive regulation of intracellular transport GO:0032388 104 0.026
cell projection morphogenesis GO:0048858 129 0.026
Fly
regulation of neuron differentiation GO:0045664 70 0.026
Fly
response to hormone GO:0009725 175 0.026
peroxisome organization GO:0007031 28 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
salivary gland morphogenesis GO:0007435 4 0.025
inorganic cation transmembrane transport GO:0098662 194 0.024
response to radiation GO:0009314 151 0.024
Fly
cardiac muscle contraction GO:0060048 34 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
single organism reproductive process GO:0044702 98 0.024
organelle assembly GO:0070925 176 0.023
regulation of intracellular transport GO:0032386 195 0.023
reproductive process GO:0022414 106 0.023
neurological system process GO:0050877 163 0.023
negative regulation of cell cycle GO:0045786 193 0.023
somatic stem cell maintenance GO:0035019 4 0.023
protein kinase b signaling GO:0043491 69 0.022
cell morphogenesis GO:0000902 296 0.022
Fly
positive regulation of immune system process GO:0002684 283 0.022
cell junction organization GO:0034330 79 0.022
embryonic morphogenesis GO:0048598 85 0.022
oogenesis GO:0048477 2 0.021
actin filament based process GO:0030029 224 0.021
regulation of protein transport GO:0051223 213 0.021
negative regulation of locomotion GO:0040013 118 0.021
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.021
metal ion transport GO:0030001 272 0.021
extrinsic apoptotic signaling pathway GO:0097191 119 0.021
nucleus localization GO:0051647 1 0.021
organ formation GO:0048645 3 0.021
jnk cascade GO:0007254 80 0.021
heart development GO:0007507 95 0.021
Mouse
cell cycle arrest GO:0007050 71 0.021
neuron projection development GO:0031175 106 0.021
Fly
cell cycle phase transition GO:0044770 173 0.021
regulation of mrna metabolic process GO:1903311 53 0.021
microtubule cytoskeleton organization GO:0000226 176 0.021
long term memory GO:0007616 2 0.020
regulation of actin filament based process GO:0032970 141 0.020
negative regulation of protein modification process GO:0031400 200 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
compound eye development GO:0048749 1 0.020
Fly
actin filament based movement GO:0030048 17 0.020
nuclear division GO:0000280 128 0.020
locomotory behavior GO:0007626 1 0.020
establishment of protein localization to membrane GO:0090150 121 0.020
oocyte development GO:0048599 1 0.020
sensory organ development GO:0007423 52 0.020
Fly
regulation of cell division GO:0051302 116 0.020
maintenance of location in cell GO:0051651 62 0.020
anterior posterior axis specification GO:0009948 2 0.020
muscle cell differentiation GO:0042692 63 0.020
regulation of protein complex assembly GO:0043254 147 0.020
spermatid development GO:0007286 4 0.019
substantia nigra development GO:0021762 45 0.019
positive regulation of transport GO:0051050 336 0.019
regulation of gtpase activity GO:0043087 180 0.019
neural nucleus development GO:0048857 47 0.019
negative regulation of protein phosphorylation GO:0001933 140 0.019
mrna metabolic process GO:0016071 175 0.019
positive regulation of cell motility GO:2000147 177 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
regulation of cell migration GO:0030334 289 0.019
positive regulation of apoptotic signaling pathway GO:2001235 70 0.019
positive regulation of protein ubiquitination GO:0031398 53 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
brain development GO:0007420 97 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
axon cargo transport GO:0008088 2 0.019
mrna processing GO:0006397 133 0.019
negative regulation of organ growth GO:0046621 5 0.018
Mouse
ion transmembrane transport GO:0034220 338 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
apoptotic signaling pathway GO:0097190 268 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
microtubule organizing center organization GO:0031023 62 0.018
cell cycle g1 s phase transition GO:0044843 80 0.018
cell adhesion GO:0007155 325 0.018
tube closure GO:0060606 3 0.018
monovalent inorganic cation transport GO:0015672 128 0.018
regulation of membrane potential GO:0042391 95 0.018
regulation of glial cell proliferation GO:0060251 4 0.018
neural crest cell development GO:0014032 3 0.018
placenta development GO:0001890 10 0.018
protein localization to nucleus GO:0034504 136 0.018
negative regulation of multicellular organismal process GO:0051241 317 0.018
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
g1 s transition of mitotic cell cycle GO:0000082 78 0.018
regulation of cytoskeleton organization GO:0051493 177 0.017
hindbrain development GO:0030902 3 0.017
tripartite regional subdivision GO:0007351 2 0.017
microtubule based process GO:0007017 210 0.017
regulation of blood circulation GO:1903522 59 0.017
regulation of stress activated mapk cascade GO:0032872 84 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
cell matrix adhesion GO:0007160 85 0.017
hemopoiesis GO:0030097 180 0.017
response to fungus GO:0009620 4 0.017
epithelial tube morphogenesis GO:0060562 38 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
regulation of ion transmembrane transporter activity GO:0032412 72 0.017
regulation of metal ion transport GO:0010959 120 0.017
regulation of protein kinase activity GO:0045859 289 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
Mouse
cardiovascular system development GO:0072358 262 0.017
Mouse
organophosphate catabolic process GO:0046434 430 0.017
negative regulation of mapk cascade GO:0043409 56 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
positive regulation of cell migration GO:0030335 172 0.016
regulation of transmembrane transporter activity GO:0022898 74 0.016
lymphocyte activation GO:0046649 133 0.016
primary neural tube formation GO:0014020 3 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
dephosphorylation GO:0016311 209 0.016
regulation of actin filament length GO:0030832 56 0.016
muscle fiber development GO:0048747 16 0.016
rna catabolic process GO:0006401 71 0.016
response to abiotic stimulus GO:0009628 336 0.016
Fly
regulation of cell differentiation GO:0045595 393 0.016
Mouse Fly
regulation of ion transport GO:0043269 189 0.016
regulation of transporter activity GO:0032409 82 0.016
negative regulation of hippo signaling GO:0035331 6 0.016
positive regulation of binding GO:0051099 45 0.016
action potential GO:0001508 34 0.016
protein localization to organelle GO:0033365 280 0.015
cytoskeleton dependent intracellular transport GO:0030705 21 0.015
positive regulation of locomotion GO:0040017 186 0.015
mrna catabolic process GO:0006402 56 0.015
rhythmic behavior GO:0007622 2 0.015
regulation of protein ubiquitination GO:0031396 95 0.015
skin development GO:0043588 76 0.015
Mouse
oocyte differentiation GO:0009994 2 0.015
negative regulation of cell migration GO:0030336 102 0.015
developmental process involved in reproduction GO:0003006 66 0.015
axis elongation GO:0003401 4 0.015
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of transmembrane transport GO:0034762 139 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
motor neuron axon guidance GO:0008045 2 0.015
midbrain development GO:0030901 45 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
regulation of cell projection organization GO:0031344 107 0.015
Fly
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
maintenance of protein location in cell GO:0032507 56 0.015
response to cocaine GO:0042220 1 0.015
cytokinesis GO:0000910 96 0.015
cilium organization GO:0044782 68 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.014
positive regulation of kinase activity GO:0033674 204 0.014
sister chromatid segregation GO:0000819 54 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
pituitary gland development GO:0021983 2 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
cytoplasmic transport GO:0016482 379 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
embryo development GO:0009790 123 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
head development GO:0060322 108 0.014
ncrna metabolic process GO:0034660 108 0.014
single organism membrane organization GO:0044802 268 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
circadian behavior GO:0048512 2 0.014
stem cell differentiation GO:0048863 93 0.014
Mouse Fly
regulation of sodium ion transport GO:0002028 24 0.013
inner ear morphogenesis GO:0042472 4 0.013
regulation of protein kinase b signaling GO:0051896 61 0.013
striated muscle cell differentiation GO:0051146 43 0.013
microtubule based movement GO:0007018 32 0.013
regulation of leukocyte migration GO:0002685 63 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
muscle cell development GO:0055001 29 0.013
response to organonitrogen compound GO:0010243 156 0.013
establishment of tissue polarity GO:0007164 3 0.013
regulation of developmental growth GO:0048638 30 0.013
Mouse Fly
transmembrane transport GO:0055085 399 0.013
cation transport GO:0006812 331 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
response to organic cyclic compound GO:0014070 204 0.013
regulation of anatomical structure size GO:0090066 101 0.013
negative regulation of kinase activity GO:0033673 106 0.013
striated muscle contraction GO:0006941 52 0.013
cell fate determination GO:0001709 3 0.013
post embryonic organ development GO:0048569 1 0.013
protein localization to microtubule cytoskeleton GO:0072698 10 0.013
regulation of sodium ion transmembrane transport GO:1902305 23 0.013
rna interference GO:0016246 4 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
pattern specification process GO:0007389 43 0.012
regulation of secretion by cell GO:1903530 177 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
neuroendocrine cell differentiation GO:0061101 2 0.012
negative regulation of cell death GO:0060548 345 0.012
male meiosis GO:0007140 1 0.012
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.012
Fly
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
cilium morphogenesis GO:0060271 75 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
neural tube closure GO:0001843 3 0.012
regulation of organ growth GO:0046620 7 0.012
Mouse
golgi vesicle transport GO:0048193 80 0.012
trna metabolic process GO:0006399 35 0.012
trna modification GO:0006400 10 0.012
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.011
neurotransmitter secretion GO:0007269 4 0.011
positive regulation of transferase activity GO:0051347 227 0.011
cell activation GO:0001775 213 0.011
maintenance of protein location GO:0045185 57 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
tube formation GO:0035148 10 0.011
membrane organization GO:0061024 292 0.011
protein homooligomerization GO:0051260 100 0.011
cellular response to lipid GO:0071396 127 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
vesicle mediated transport GO:0016192 371 0.011
meiotic chromosome segregation GO:0045132 4 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
ncrna processing GO:0034470 83 0.011
reproductive system development GO:0061458 56 0.011
generation of neurons GO:0048699 152 0.011
Fly
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.011
negative regulation of epithelial cell proliferation GO:0050680 48 0.011
Mouse
actin filament polymerization GO:0030041 45 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
negative regulation of cell motility GO:2000146 104 0.011
protein maturation GO:0051604 233 0.011
positive regulation of neural precursor cell proliferation GO:2000179 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
circulatory system process GO:0003013 113 0.011
cellular protein complex assembly GO:0043623 188 0.011
response to hypoxia GO:0001666 96 0.011
developmental growth GO:0048589 48 0.011
Mouse Fly
striated muscle cell development GO:0055002 27 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
tissue regeneration GO:0042246 3 0.010
secretion by cell GO:0032940 226 0.010
regulation of actin polymerization or depolymerization GO:0008064 56 0.010
endodermal cell fate specification GO:0001714 4 0.010
regulation of organ formation GO:0003156 4 0.010
response to axon injury GO:0048678 1 0.010
negative regulation of developmental growth GO:0048640 10 0.010
Mouse
reproduction GO:0000003 63 0.010
cell type specific apoptotic process GO:0097285 125 0.010
leukocyte migration GO:0050900 107 0.010
stem cell division GO:0017145 2 0.010
cell junction assembly GO:0034329 67 0.010
single organism cellular localization GO:1902580 332 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
Fly
positive regulation of gliogenesis GO:0014015 4 0.010
regulation of heart contraction GO:0008016 50 0.010
regulation of heart rate GO:0002027 38 0.010
positive regulation of cell cycle GO:0045787 140 0.010
cellular lipid metabolic process GO:0044255 303 0.010
sodium ion transmembrane transport GO:0035725 59 0.010
organ growth GO:0035265 12 0.010
Mouse

SAV1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.031
disease of cellular proliferation DOID:14566 174 0.031
organ system cancer DOID:0050686 164 0.031
sensory system disease DOID:0050155 203 0.022
nervous system disease DOID:863 431 0.022
disease of metabolism DOID:0014667 295 0.018
joubert syndrome DOID:0050777 18 0.018
cardiovascular system disease DOID:1287 106 0.016
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
musculoskeletal system disease DOID:17 223 0.012
retinal disease DOID:5679 118 0.010
retinal degeneration DOID:8466 89 0.010