Homo sapiens

49 known processes

SDHA

succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

(Aliases: FP,SDH1,SDH2,CMD1GG,SDHF)

SDHA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.986
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.977
Yeast
atp synthesis coupled electron transport GO:0042773 4 0.941
Yeast
multicellular organismal aging GO:0010259 3 0.930
dicarboxylic acid metabolic process GO:0043648 29 0.801
generation of precursor metabolites and energy GO:0006091 68 0.741
ribonucleoside monophosphate metabolic process GO:0009161 187 0.734
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.664
Yeast
post embryonic development GO:0009791 2 0.640
cellular respiration GO:0045333 21 0.614
cellular lipid catabolic process GO:0044242 65 0.600
atp metabolic process GO:0046034 176 0.593
Yeast
energy derivation by oxidation of organic compounds GO:0015980 43 0.562
purine nucleoside monophosphate metabolic process GO:0009126 186 0.561
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.560
Yeast
determination of adult lifespan GO:0008340 2 0.548
ribonucleoside triphosphate metabolic process GO:0009199 412 0.522
Yeast
tricarboxylic acid metabolic process GO:0072350 4 0.517
oxidative phosphorylation GO:0006119 10 0.466
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.460
Yeast
tricarboxylic acid cycle GO:0006099 4 0.424
nucleoside monophosphate metabolic process GO:0009123 191 0.395
Yeast
lipid metabolic process GO:0006629 381 0.395
succinate metabolic process GO:0006105 1 0.390
mitochondrial electron transport nadh to ubiquinone GO:0006120 2 0.371
oogenesis GO:0048477 2 0.371
electron transport chain GO:0022900 8 0.358
aerobic respiration GO:0009060 7 0.351
mitochondrial respiratory chain complex i assembly GO:0032981 16 0.273
mitochondrial respiratory chain complex assembly GO:0033108 23 0.273
purine nucleoside triphosphate metabolic process GO:0009144 412 0.260
Yeast
nadh metabolic process GO:0006734 1 0.258
citrate metabolic process GO:0006101 2 0.252
respiratory electron transport chain GO:0022904 7 0.216
nadh dehydrogenase complex assembly GO:0010257 16 0.212
system process GO:0003008 349 0.201
vesicle mediated transport GO:0016192 371 0.172
carboxylic acid catabolic process GO:0046395 71 0.171
cellular protein complex assembly GO:0043623 188 0.139
female gamete generation GO:0007292 2 0.133
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.133
Yeast
isocitrate metabolic process GO:0006102 1 0.130
lipid oxidation GO:0034440 33 0.114
nervous system development GO:0007399 293 0.101
small molecule catabolic process GO:0044282 92 0.094
mitochondrion organization GO:0007005 156 0.090
organic acid catabolic process GO:0016054 71 0.086
cellular macromolecular complex assembly GO:0034622 324 0.082
response to drug GO:0042493 81 0.081
lipid catabolic process GO:0016042 84 0.078
embryo development GO:0009790 123 0.077
Worm
neuroblast proliferation GO:0007405 4 0.076
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.076
mating GO:0007618 1 0.076
anatomical structure formation involved in morphogenesis GO:0048646 284 0.072
cellular amino acid metabolic process GO:0006520 116 0.070
dicarboxylic acid biosynthetic process GO:0043650 4 0.066
coenzyme metabolic process GO:0006732 65 0.063
monocarboxylic acid catabolic process GO:0072329 37 0.062
neuromuscular junction development GO:0007528 3 0.058
protein processing GO:0016485 226 0.057
chemical homeostasis GO:0048878 306 0.054
membrane organization GO:0061024 292 0.054
regulation of neural precursor cell proliferation GO:2000177 4 0.054
negative regulation of cell death GO:0060548 345 0.053
monocarboxylic acid metabolic process GO:0032787 185 0.052
2 oxoglutarate metabolic process GO:0006103 4 0.051
growth GO:0040007 202 0.050
cell cell signaling GO:0007267 155 0.050
locomotory behavior GO:0007626 1 0.049
carbohydrate metabolic process GO:0005975 207 0.048
cellular ketone metabolic process GO:0042180 80 0.047
maintenance of location GO:0051235 112 0.047
aging GO:0007568 66 0.047
endocytosis GO:0006897 159 0.046
negative regulation of programmed cell death GO:0043069 321 0.045
regulation of cellular amine metabolic process GO:0033238 11 0.045
cell development GO:0048468 328 0.043
mitochondrial membrane organization GO:0007006 40 0.041
lipid modification GO:0030258 84 0.041
reproductive system development GO:0061458 56 0.041
actin filament based process GO:0030029 224 0.039
cell differentiation in spinal cord GO:0021515 1 0.039
cellular cation homeostasis GO:0030003 163 0.038
negative regulation of cell proliferation GO:0008285 228 0.038
cellular amine metabolic process GO:0044106 41 0.037
regulation of cellular ketone metabolic process GO:0010565 50 0.037
amine metabolic process GO:0009308 44 0.036
sulfur compound biosynthetic process GO:0044272 38 0.035
cellular component morphogenesis GO:0032989 314 0.035
circulatory system development GO:0072359 262 0.035
head development GO:0060322 108 0.034
cellular ion homeostasis GO:0006873 168 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
receptor mediated endocytosis GO:0006898 84 0.033
muscle contraction GO:0006936 73 0.033
single organism cellular localization GO:1902580 332 0.032
cardiovascular system development GO:0072358 262 0.032
ion homeostasis GO:0050801 230 0.032
protein maturation GO:0051604 233 0.031
small molecule biosynthetic process GO:0044283 157 0.031
behavior GO:0007610 112 0.030
negative regulation of apoptotic process GO:0043066 316 0.030
neurogenesis GO:0022008 169 0.029
single organism reproductive process GO:0044702 98 0.029
rna interference GO:0016246 4 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
cellular homeostasis GO:0019725 196 0.029
spinal cord development GO:0021510 4 0.029
response to hormone GO:0009725 175 0.028
nitrogen compound transport GO:0071705 191 0.027
pyridine containing compound metabolic process GO:0072524 18 0.027
cation homeostasis GO:0055080 189 0.027
response to abiotic stimulus GO:0009628 336 0.026
fatty acid oxidation GO:0019395 31 0.026
protein localization to membrane GO:0072657 160 0.025
myosin filament assembly GO:0031034 2 0.025
anion transport GO:0006820 161 0.025
reproduction GO:0000003 63 0.025
memory GO:0007613 3 0.025
negative regulation of apoptotic signaling pathway GO:2001234 97 0.025
spermatid differentiation GO:0048515 4 0.025
sex differentiation GO:0007548 45 0.025
reproductive structure development GO:0048608 55 0.025
regulation of proteolysis GO:0030162 293 0.024
metal ion homeostasis GO:0055065 169 0.024
single organism membrane organization GO:0044802 268 0.024
cation transport GO:0006812 331 0.023
glutamate metabolic process GO:0006536 10 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
carboxylic acid biosynthetic process GO:0046394 97 0.023
fatty acid metabolic process GO:0006631 115 0.023
excretion GO:0007588 9 0.023
negative regulation of stem cell proliferation GO:2000647 3 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
regulation of neuroblast proliferation GO:1902692 3 0.022
fatty acid catabolic process GO:0009062 29 0.021
muscle system process GO:0003012 81 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
reproductive process GO:0022414 106 0.021
dephosphorylation GO:0016311 209 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
cofactor biosynthetic process GO:0051188 31 0.020
cell growth GO:0016049 160 0.020
hindbrain development GO:0030902 3 0.020
biological adhesion GO:0022610 331 0.020
proximal tubule development GO:0072014 1 0.019
regulation of growth GO:0040008 165 0.019
embryo development ending in birth or egg hatching GO:0009792 34 0.019
Worm
divalent metal ion transport GO:0070838 152 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.018
cellular lipid metabolic process GO:0044255 303 0.018
aspartate metabolic process GO:0006531 4 0.018
organic acid biosynthetic process GO:0016053 97 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
regulation of cell growth GO:0001558 135 0.018
brain development GO:0007420 97 0.018
neuron differentiation GO:0030182 138 0.018
spermatid development GO:0007286 4 0.018
internal protein amino acid acetylation GO:0006475 101 0.018
generation of neurons GO:0048699 152 0.018
establishment of protein localization to organelle GO:0072594 172 0.017
fatty acid beta oxidation GO:0006635 22 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
endomembrane system organization GO:0010256 196 0.017
embryonic morphogenesis GO:0048598 85 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
regulation of secretion by cell GO:1903530 177 0.017
cellular divalent inorganic cation homeostasis GO:0072503 128 0.017
mitotic cell cycle process GO:1903047 286 0.016
protein catabolic process GO:0030163 325 0.016
response to external biotic stimulus GO:0043207 261 0.016
negative regulation of mitotic cell cycle GO:0045930 102 0.016
protein targeting GO:0006605 187 0.016
cell part morphogenesis GO:0032990 137 0.016
response to oxidative stress GO:0006979 121 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
regeneration GO:0031099 4 0.016
response to other organism GO:0051707 261 0.016
secretion by cell GO:0032940 226 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
microtubule based process GO:0007017 210 0.015
developmental process involved in reproduction GO:0003006 66 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
ventral spinal cord development GO:0021517 1 0.015
glutamine family amino acid metabolic process GO:0009064 17 0.015
long term memory GO:0007616 2 0.015
organic anion transport GO:0015711 103 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
negative regulation of cellular protein metabolic process GO:0032269 353 0.015
action potential GO:0001508 34 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
cytoplasmic transport GO:0016482 379 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
cofactor metabolic process GO:0051186 87 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
regulation of membrane potential GO:0042391 95 0.014
cellular amino acid catabolic process GO:0009063 31 0.014
secretion GO:0046903 254 0.014
gonad development GO:0008406 34 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
protein localization to organelle GO:0033365 280 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
organic hydroxy compound biosynthetic process GO:1901617 71 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
cell cell signaling involved in cell fate commitment GO:0045168 5 0.014
divalent inorganic cation homeostasis GO:0072507 136 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
nerve development GO:0021675 4 0.013
cellular chemical homeostasis GO:0055082 180 0.013
wound healing GO:0042060 115 0.013
kidney development GO:0001822 53 0.013
lipid localization GO:0010876 106 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
cellular protein catabolic process GO:0044257 261 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
muscle cell differentiation GO:0042692 63 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
segmentation GO:0035282 4 0.013
multicellular organism reproduction GO:0032504 42 0.013
amide transport GO:0042886 76 0.013
anatomical structure homeostasis GO:0060249 100 0.013
regulation of kinase activity GO:0043549 314 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
negative regulation of protein complex assembly GO:0031333 43 0.012
regulation of protein processing GO:0070613 150 0.012
response to activity GO:0014823 0 0.012
nucleotide catabolic process GO:0009166 408 0.012
positive regulation of cell death GO:0010942 263 0.012
regulation of cell adhesion GO:0030155 166 0.012
glial cell migration GO:0008347 4 0.012
phototransduction GO:0007602 3 0.012
mitotic cell cycle GO:0000278 326 0.012
response to extracellular stimulus GO:0009991 85 0.012
pyridine nucleotide metabolic process GO:0019362 14 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
negative regulation of neural precursor cell proliferation GO:2000178 1 0.012
transmission of nerve impulse GO:0019226 11 0.012
mitochondrial transport GO:0006839 60 0.011
actin cytoskeleton organization GO:0030036 207 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
negative regulation of cell cycle GO:0045786 193 0.011
organelle assembly GO:0070925 176 0.011
angiogenesis GO:0001525 147 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
multicellular organismal signaling GO:0035637 34 0.011
response to nitrogen compound GO:1901698 184 0.011
positive regulation of proteolysis GO:0045862 142 0.011
regulation of hormone levels GO:0010817 125 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
cell cycle phase transition GO:0044770 173 0.011
calcium ion transport GO:0006816 147 0.011
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
glycerol metabolic process GO:0006071 4 0.011
visual behavior GO:0007632 2 0.011
tissue regeneration GO:0042246 3 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
metal ion transport GO:0030001 272 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
acetyl coa biosynthetic process from pyruvate GO:0006086 4 0.011
response to organonitrogen compound GO:0010243 156 0.011
response to nutrient levels GO:0031667 81 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
regulation of cell development GO:0060284 161 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
ras protein signal transduction GO:0007265 73 0.011
cell morphogenesis GO:0000902 296 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
cell projection morphogenesis GO:0048858 129 0.010
signal release GO:0023061 70 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
cell fate commitment GO:0045165 27 0.010
ribonucleoside catabolic process GO:0042454 406 0.010
negative regulation of transport GO:0051051 176 0.010
calcium ion homeostasis GO:0055074 122 0.010
negative regulation of cell differentiation GO:0045596 171 0.010
regulation of actin filament based process GO:0032970 141 0.010
metencephalon development GO:0022037 2 0.010
peptide transport GO:0015833 74 0.010
alpha amino acid metabolic process GO:1901605 72 0.010
myosin filament organization GO:0031033 2 0.010
protein import GO:0017038 130 0.010
inner ear morphogenesis GO:0042472 4 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
dicarboxylic acid catabolic process GO:0043649 9 0.010

SDHA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.904
inherited metabolic disorder DOID:655 242 0.904
disease of cellular proliferation DOID:14566 174 0.296
amino acid metabolic disorder DOID:9252 50 0.282
nervous system disease DOID:863 431 0.257
central nervous system disease DOID:331 186 0.257
cancer DOID:162 167 0.211
mitochondrial metabolism disease DOID:700 29 0.151
gastrointestinal system cancer DOID:3119 52 0.096
organ system cancer DOID:0050686 164 0.096
sensory system disease DOID:0050155 203 0.078
eye and adnexa disease DOID:1492 150 0.078
eye disease DOID:5614 149 0.078
benign neoplasm DOID:0060072 18 0.071
cell type benign neoplasm DOID:0060084 10 0.071
phaeochromocytoma DOID:0050771 8 0.071
carbohydrate metabolic disorder DOID:2978 55 0.061
retinal disease DOID:5679 118 0.049
neuropathy DOID:870 52 0.045
retinal degeneration DOID:8466 89 0.036
hematopoietic system disease DOID:74 100 0.031
immune system disease DOID:2914 155 0.031
neurodegenerative disease DOID:1289 102 0.031
retinitis pigmentosa DOID:10584 51 0.031
endocrine gland cancer DOID:170 26 0.024
leigh disease DOID:3652 16 0.021
cardiovascular system disease DOID:1287 106 0.021
coenzyme q10 deficiency disease DOID:0050730 6 0.018
brain disease DOID:936 73 0.012
anemia DOID:2355 55 0.012
spinocerebellar degeneration DOID:2478 27 0.011
charcot marie tooth disease DOID:10595 33 0.011
neuromuscular disease DOID:440 38 0.011
musculoskeletal system disease DOID:17 223 0.004
muscle tissue disease DOID:66 113 0.004
muscular disease DOID:0080000 114 0.004
myopathy DOID:423 104 0.004
heart disease DOID:114 68 0.003
cardiomyopathy DOID:0050700 50 0.003
intrinsic cardiomyopathy DOID:0060036 50 0.003
dilated cardiomyopathy DOID:12930 32 0.001
neuroendocrine tumor DOID:169 4 0.001
paraganglioma DOID:0050773 4 0.001