Homo sapiens

44 known processes

SEC61A1

Sec61 alpha 1 subunit (S. cerevisiae)

(Aliases: SEC61,HSEC61,SEC61A)

SEC61A1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.385
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.363
Yeast
protein glycosylation GO:0006486 62 0.317
macromolecule glycosylation GO:0043413 63 0.282
glycoprotein metabolic process GO:0009100 110 0.251
cytoplasmic transport GO:0016482 379 0.218
carbohydrate metabolic process GO:0005975 207 0.202
carbohydrate derivative biosynthetic process GO:1901137 207 0.195
vesicle mediated transport GO:0016192 371 0.164
establishment of protein localization to organelle GO:0072594 172 0.163
hindbrain development GO:0030902 3 0.158
glycoprotein biosynthetic process GO:0009101 91 0.157
metencephalon development GO:0022037 2 0.147
protein catabolic process GO:0030163 325 0.141
Yeast
transmembrane transport GO:0055085 399 0.132
Yeast
response to endoplasmic reticulum stress GO:0034976 49 0.130
nucleocytoplasmic transport GO:0006913 176 0.126
er nucleus signaling pathway GO:0006984 23 0.124
cellular macromolecule catabolic process GO:0044265 380 0.123
Yeast
maintenance of location GO:0051235 112 0.119
single organism carbohydrate metabolic process GO:0044723 193 0.115
cellular protein catabolic process GO:0044257 261 0.115
Yeast
enzyme linked receptor protein signaling pathway GO:0007167 303 0.113
single organism nuclear import GO:1902593 104 0.113
response to unfolded protein GO:0006986 24 0.112
glycosylation GO:0070085 71 0.112
endoplasmic reticulum unfolded protein response GO:0030968 16 0.109
ion homeostasis GO:0050801 230 0.107
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.106
Yeast
cellular response to topologically incorrect protein GO:0035967 19 0.106
secretion GO:0046903 254 0.102
response to abiotic stimulus GO:0009628 336 0.092
protein localization to organelle GO:0033365 280 0.086
cellular ion homeostasis GO:0006873 168 0.085
protein targeting GO:0006605 187 0.082
chemical homeostasis GO:0048878 306 0.082
determination of adult lifespan GO:0008340 2 0.081
lipid localization GO:0010876 106 0.076
modification dependent protein catabolic process GO:0019941 209 0.074
Yeast
er to golgi vesicle mediated transport GO:0006888 19 0.068
modification dependent macromolecule catabolic process GO:0043632 212 0.066
Yeast
cellular homeostasis GO:0019725 196 0.062
cell cell signaling GO:0007267 155 0.060
response to decreased oxygen levels GO:0036293 96 0.058
intrinsic apoptotic signaling pathway GO:0097193 127 0.057
regulation of ion transport GO:0043269 189 0.054
intracellular protein transport GO:0006886 270 0.054
cerebellum development GO:0021549 2 0.053
ubiquitin dependent protein catabolic process GO:0006511 206 0.052
Yeast
positive regulation of hydrolase activity GO:0051345 331 0.050
apoptotic signaling pathway GO:0097190 268 0.048
response to biotic stimulus GO:0009607 276 0.048
positive regulation of catabolic process GO:0009896 310 0.048
synaptic vesicle endocytosis GO:0048488 2 0.047
response to external biotic stimulus GO:0043207 261 0.045
compound eye development GO:0048749 1 0.044
response to other organism GO:0051707 261 0.044
positive regulation of transferase activity GO:0051347 227 0.043
regulation of cytoplasmic transport GO:1903649 149 0.042
protein localization to nucleus GO:0034504 136 0.042
cellular divalent inorganic cation homeostasis GO:0072503 128 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.041
Yeast
divalent inorganic cation homeostasis GO:0072507 136 0.041
endomembrane system organization GO:0010256 196 0.041
protein localization to endoplasmic reticulum GO:0070972 19 0.040
cellular metal ion homeostasis GO:0006875 146 0.040
cation homeostasis GO:0055080 189 0.039
response to virus GO:0009615 126 0.039
single organism cellular localization GO:1902580 332 0.039
cellular chemical homeostasis GO:0055082 180 0.039
metal ion homeostasis GO:0055065 169 0.038
protein secretion GO:0009306 98 0.038
cellular response to unfolded protein GO:0034620 16 0.038
ribonucleotide catabolic process GO:0009261 405 0.036
cellular response to endogenous stimulus GO:0071495 336 0.036
regeneration GO:0031099 4 0.036
establishment of vesicle localization GO:0051650 23 0.036
organophosphate catabolic process GO:0046434 430 0.033
regulation of apoptotic signaling pathway GO:2001233 175 0.033
posttranslational protein targeting to membrane GO:0006620 5 0.033
cation transport GO:0006812 331 0.032
activation of signaling protein activity involved in unfolded protein response GO:0006987 3 0.032
regulation of protein localization GO:0032880 296 0.032
cellular response to organic cyclic compound GO:0071407 127 0.032
synaptic vesicle recycling GO:0036465 3 0.031
regulation of intracellular transport GO:0032386 195 0.031
positive regulation of immune system process GO:0002684 283 0.030
protein targeting to nucleus GO:0044744 104 0.030
immune effector process GO:0002252 159 0.029
positive regulation of transport GO:0051050 336 0.029
brain development GO:0007420 97 0.029
Zebrafish
cellular cation homeostasis GO:0030003 163 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
golgi vesicle transport GO:0048193 80 0.028
lipid storage GO:0019915 28 0.028
positive regulation of cellular protein catabolic process GO:1903364 37 0.027
vasodilation GO:0042311 4 0.027
cytokinesis GO:0000910 96 0.027
regulation of metal ion transport GO:0010959 120 0.027
mitochondrial calcium ion homeostasis GO:0051560 11 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
endocytosis GO:0006897 159 0.026
response to cytokine GO:0034097 232 0.026
metal ion transport GO:0030001 272 0.026
secretion by cell GO:0032940 226 0.026
nuclear import GO:0051170 106 0.025
eye pigmentation GO:0048069 1 0.025
protein localization to membrane GO:0072657 160 0.025
cardiac muscle cell contraction GO:0086003 4 0.024
regulation of nucleocytoplasmic transport GO:0046822 98 0.024
response to hypoxia GO:0001666 96 0.024
positive regulation of apoptotic signaling pathway GO:2001235 70 0.024
protein import into nucleus GO:0006606 104 0.023
regulation of wnt protein secretion GO:0061356 1 0.023
embryo development GO:0009790 123 0.023
regulation of response to external stimulus GO:0032101 222 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
leukocyte activation GO:0045321 164 0.022
protein import GO:0017038 130 0.022
Yeast
negative regulation of programmed cell death GO:0043069 321 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
positive regulation of cytoplasmic transport GO:1903651 82 0.022
cellular amine metabolic process GO:0044106 41 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
Yeast
nitrogen compound transport GO:0071705 191 0.021
Yeast
locomotory behavior GO:0007626 1 0.021
positive regulation of organelle organization GO:0010638 195 0.021
cell division GO:0051301 168 0.021
response to nitrogen compound GO:1901698 184 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
protein n linked glycosylation GO:0006487 23 0.020
response to oxygen levels GO:0070482 100 0.020
calcium ion transport GO:0006816 147 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.019
immune response GO:0006955 307 0.019
response to axon injury GO:0048678 1 0.019
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.019
response to topologically incorrect protein GO:0035966 29 0.019
behavior GO:0007610 112 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
multicellular organismal aging GO:0010259 3 0.018
response to uv GO:0009411 73 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
regulation of calcium ion transport GO:0051924 79 0.018
response to growth factor GO:0070848 205 0.018
regulation of protein catabolic process GO:0042176 155 0.017
circulatory system process GO:0003013 113 0.017
lipid biosynthetic process GO:0008610 177 0.017
regulation of reactive oxygen species metabolic process GO:2000377 41 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
regulation of homeostatic process GO:0032844 121 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
regulation of locomotion GO:0040012 329 0.017
response to oxygen containing compound GO:1901700 369 0.016
cellular calcium ion homeostasis GO:0006874 117 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
cellular response to toxic substance GO:0097237 4 0.016
head development GO:0060322 108 0.016
Zebrafish
regulation of multi organism process GO:0043900 157 0.016
regulation of protein localization to nucleus GO:1900180 85 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
positive regulation of intracellular protein transport GO:0090316 76 0.015
establishment of viral latency GO:0019043 1 0.015
regulation of defense response GO:0031347 154 0.015
regulation of behavior GO:0050795 82 0.015
divalent metal ion transport GO:0070838 152 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
regulation of protein transport GO:0051223 213 0.015
axon regeneration GO:0031103 1 0.015
cellular response to external stimulus GO:0071496 111 0.015
exocytosis GO:0006887 71 0.015
system process GO:0003008 349 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
positive regulation of cell death GO:0010942 263 0.015
cell activation GO:0001775 213 0.015
membrane organization GO:0061024 292 0.015
cell development GO:0048468 328 0.015
fatty acid metabolic process GO:0006631 115 0.014
nuclear transport GO:0051169 179 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
female gamete generation GO:0007292 2 0.014
regulation of cellular response to stress GO:0080135 244 0.014
response to transforming growth factor beta GO:0071559 94 0.014
tube development GO:0035295 125 0.014
spermatid differentiation GO:0048515 4 0.014
response to hormone GO:0009725 175 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
lipid metabolic process GO:0006629 381 0.014
calcium ion homeostasis GO:0055074 122 0.014
receptor mediated endocytosis GO:0006898 84 0.014
regulation of defense response to virus by host GO:0050691 22 0.013
anion transport GO:0006820 161 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
wnt protein secretion GO:0061355 1 0.013
lymphocyte activation GO:0046649 133 0.013
regulation of binding GO:0051098 111 0.013
response to inorganic substance GO:0010035 127 0.013
response to nutrient levels GO:0031667 81 0.013
rna interference GO:0016246 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
response to starvation GO:0042594 59 0.013
cerebellar cortex development GO:0021695 1 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.012
regulation of ion homeostasis GO:2000021 73 0.012
lipid modification GO:0030258 84 0.012
reproduction GO:0000003 63 0.012
cytosolic calcium ion homeostasis GO:0051480 89 0.012
peripheral nervous system development GO:0007422 2 0.012
midbrain development GO:0030901 45 0.012
maintenance of location in cell GO:0051651 62 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
blood circulation GO:0008015 113 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
regulation of erbb signaling pathway GO:1901184 27 0.012
defense response to virus GO:0051607 71 0.012
segmentation GO:0035282 4 0.012
pigment biosynthetic process GO:0046148 10 0.012
negative regulation of cell death GO:0060548 345 0.012
establishment of organelle localization GO:0051656 59 0.011
spermatid development GO:0007286 4 0.011
divalent inorganic cation transport GO:0072511 158 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
positive regulation of immune response GO:0050778 159 0.011
cellular transition metal ion homeostasis GO:0046916 21 0.011
purine containing compound catabolic process GO:0072523 411 0.011
positive regulation of cell motility GO:2000147 177 0.011
regulation of protein targeting GO:1903533 91 0.011
positive regulation of protein transport GO:0051222 135 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
regulation of defense response to virus GO:0050688 33 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
positive regulation of proteolysis GO:0045862 142 0.011
vesicle organization GO:0016050 62 0.011
modified amino acid transport GO:0072337 11 0.011
response to steroid hormone GO:0048545 80 0.011
actin filament based process GO:0030029 224 0.011
positive regulation of calcium ion transport GO:0051928 51 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
protein import into nucleus translocation GO:0000060 22 0.011
regulation of membrane potential GO:0042391 95 0.011
response to organic cyclic compound GO:0014070 204 0.010
oocyte differentiation GO:0009994 2 0.010
cellular response to oxygen levels GO:0071453 55 0.010
cellular response to nutrient levels GO:0031669 69 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.010
organelle localization GO:0051640 84 0.010
endoplasmic reticulum organization GO:0007029 20 0.010
protein oligomerization GO:0051259 173 0.010
regulation of cellular component movement GO:0051270 334 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
single organism membrane organization GO:0044802 268 0.010
regulation of cell motility GO:2000145 299 0.010
actin mediated cell contraction GO:0070252 12 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010

SEC61A1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.054
carbohydrate metabolic disorder DOID:2978 55 0.054
inherited metabolic disorder DOID:655 242 0.054
bone development disease DOID:0080006 55 0.046
bone disease DOID:0080001 88 0.046
musculoskeletal system disease DOID:17 223 0.046
connective tissue disease DOID:65 109 0.046
central nervous system disease DOID:331 186 0.018
nervous system disease DOID:863 431 0.018
neurodegenerative disease DOID:1289 102 0.015
congenital disorder of glycosylation DOID:5212 26 0.013