Homo sapiens

332 known processes

SEMA4D

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

(Aliases: MGC169138,CD100,M-sema-G,MGC169141,FLJ39737,C9orf164,SEMAJ,coll-4,FLJ33485,FLJ46484,FLJ34282)

SEMA4D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gamma delta t cell activation GO:0046629 3 0.237
cellular amine metabolic process GO:0044106 41 0.191
cellular ketone metabolic process GO:0042180 80 0.178
motor neuron axon guidance GO:0008045 2 0.175
amine metabolic process GO:0009308 44 0.152
sequestering of metal ion GO:0051238 24 0.144
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.140
immunoglobulin biosynthetic process GO:0002378 2 0.133
negative regulation of cellular amine metabolic process GO:0033239 3 0.129
sequestering of calcium ion GO:0051208 17 0.123
cation transport GO:0006812 331 0.121
cellular amino acid metabolic process GO:0006520 116 0.118
bone marrow development GO:0048539 3 0.112
regulation of cellular amine metabolic process GO:0033238 11 0.106
positive regulation of cellular amine metabolic process GO:0033240 7 0.104
signal transduction by phosphorylation GO:0023014 297 0.103
Human
protein autophosphorylation GO:0046777 123 0.094
divalent metal ion transport GO:0070838 152 0.091
post embryonic development GO:0009791 2 0.091
regulation of cell migration GO:0030334 289 0.090
response to abiotic stimulus GO:0009628 336 0.086
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.086
cellular calcium ion homeostasis GO:0006874 117 0.086
regulation of gamma delta t cell activation GO:0046643 1 0.086
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.084
purine ribonucleoside metabolic process GO:0046128 437 0.084
negative regulation of phosphorylation GO:0042326 174 0.083
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.081
positive regulation of antigen receptor mediated signaling pathway GO:0050857 3 0.080
cytoplasmic transport GO:0016482 379 0.080
positive regulation of cell death GO:0010942 263 0.079
cell morphogenesis GO:0000902 296 0.079
dephosphorylation GO:0016311 209 0.078
gtp catabolic process GO:0006184 237 0.077
post embryonic organ development GO:0048569 1 0.077
metal ion transport GO:0030001 272 0.077
nucleotide catabolic process GO:0009166 408 0.076
positive regulation of humoral immune response GO:0002922 3 0.076
regulation of cellular amino acid metabolic process GO:0006521 6 0.075
regulation of kinase activity GO:0043549 314 0.075
purine nucleoside triphosphate catabolic process GO:0009146 392 0.074
regulation of b cell differentiation GO:0045577 2 0.073
positive regulation of developmental process GO:0051094 314 0.073
regulation of cell differentiation GO:0045595 393 0.073
positive regulation of isotype switching GO:0045830 2 0.072
cellular response to endogenous stimulus GO:0071495 336 0.072
negative regulation of phosphorus metabolic process GO:0010563 267 0.072
neuromuscular junction development GO:0007528 3 0.072
negative regulation of cellular protein metabolic process GO:0032269 353 0.071
Mouse
regulation of transferase activity GO:0051338 355 0.070
divalent inorganic cation transport GO:0072511 158 0.070
positive regulation of mapk cascade GO:0043410 190 0.070
Human
regulation of mapk cascade GO:0043408 262 0.070
Human
regulation of b cell receptor signaling pathway GO:0050855 4 0.069
positive regulation of cell migration GO:0030335 172 0.069
negative regulation of protein phosphorylation GO:0001933 140 0.068
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.068
regulation of cell cycle GO:0051726 393 0.067
regulation of cell motility GO:2000145 299 0.066
apoptotic signaling pathway GO:0097190 268 0.065
ribonucleoside triphosphate catabolic process GO:0009203 391 0.065
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.065
negative regulation of protein modification process GO:0031400 200 0.065
Mouse
cellular component morphogenesis GO:0032989 314 0.065
maintenance of location GO:0051235 112 0.065
cellular response to cytokine stimulus GO:0071345 181 0.064
cytokine mediated signaling pathway GO:0019221 109 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.062
negative regulation of cell adhesion GO:0007162 64 0.062
response to oxygen containing compound GO:1901700 369 0.061
positive regulation of immune system process GO:0002684 283 0.061
negative regulation of phosphate metabolic process GO:0045936 267 0.061
immune response GO:0006955 307 0.060
negative regulation of catalytic activity GO:0043086 335 0.060
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.060
negative regulation of protein metabolic process GO:0051248 391 0.060
Mouse
response to cytokine GO:0034097 232 0.060
positive regulation of apoptotic process GO:0043065 246 0.059
cellular ion homeostasis GO:0006873 168 0.059
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.059
Mouse
positive regulation of b cell mediated immunity GO:0002714 4 0.058
purine containing compound catabolic process GO:0072523 411 0.058
nervous system development GO:0007399 293 0.057
protein dephosphorylation GO:0006470 81 0.057
calcium ion homeostasis GO:0055074 122 0.056
behavioral response to ethanol GO:0048149 2 0.056
positive regulation of gamma delta t cell activation GO:0046645 1 0.056
metal ion homeostasis GO:0055065 169 0.056
negative regulation of homeostatic process GO:0032845 59 0.055
glycosyl compound catabolic process GO:1901658 413 0.055
defense response GO:0006952 315 0.055
regulation of protein kinase activity GO:0045859 289 0.054
positive regulation of phosphorylation GO:0042327 394 0.054
cellular cation homeostasis GO:0030003 163 0.054
peptidyl tyrosine phosphorylation GO:0018108 170 0.053
Mouse
organophosphate catabolic process GO:0046434 430 0.053
negative regulation of cellular component organization GO:0051129 235 0.053
nucleoside triphosphate catabolic process GO:0009143 394 0.053
chemotaxis GO:0006935 157 0.052
Human Fly
ectoderm development GO:0007398 3 0.052
gtp metabolic process GO:0046039 239 0.052
vesicle mediated transport GO:0016192 371 0.052
positive regulation of kinase activity GO:0033674 204 0.052
purine ribonucleoside catabolic process GO:0046130 398 0.051
single organism membrane organization GO:0044802 268 0.051
positive regulation of programmed cell death GO:0043068 249 0.051
guanosine containing compound metabolic process GO:1901068 244 0.051
cell projection organization GO:0030030 252 0.050
skeletal system development GO:0001501 79 0.050
oocyte differentiation GO:0009994 2 0.050
cation homeostasis GO:0055080 189 0.050
regulation of locomotion GO:0040012 329 0.049
positive regulation of nucleotide metabolic process GO:0045981 230 0.049
cellular metal ion homeostasis GO:0006875 146 0.049
positive regulation of transferase activity GO:0051347 227 0.049
negative regulation of sequestering of calcium ion GO:0051283 41 0.049
cell adhesion GO:0007155 325 0.048
positive regulation of cellular component organization GO:0051130 376 0.048
t cell selection GO:0045058 4 0.048
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.047
cell cell signaling GO:0007267 155 0.047
defense response to virus GO:0051607 71 0.047
guanosine containing compound catabolic process GO:1901069 239 0.047
activation of mapk activity GO:0000187 45 0.046
regulation of gtp catabolic process GO:0033124 180 0.046
rho protein signal transduction GO:0007266 26 0.046
positive regulation of catabolic process GO:0009896 310 0.046
chemical homeostasis GO:0048878 306 0.045
biological adhesion GO:0022610 331 0.045
cell cycle phase transition GO:0044770 173 0.045
peptidyl tyrosine modification GO:0018212 170 0.045
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.044
female gamete generation GO:0007292 2 0.044
small gtpase mediated signal transduction GO:0007264 78 0.044
positive regulation of protein kinase activity GO:0045860 190 0.043
immune system development GO:0002520 195 0.043
positive regulation of apoptotic signaling pathway GO:2001235 70 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.042
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.042
divalent inorganic cation homeostasis GO:0072507 136 0.041
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.041
regulation of dna metabolic process GO:0051052 153 0.041
purine nucleoside catabolic process GO:0006152 398 0.041
purine nucleotide catabolic process GO:0006195 405 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.041
regulation of apoptotic signaling pathway GO:2001233 175 0.040
taxis GO:0042330 157 0.040
Human Fly
immune effector process GO:0002252 159 0.040
hematopoietic or lymphoid organ development GO:0048534 186 0.040
regulation of nucleoside metabolic process GO:0009118 209 0.040
system process GO:0003008 349 0.040
positive regulation of hydrolase activity GO:0051345 331 0.040
negative regulation of developmental process GO:0051093 247 0.039
Mouse
regulation of cellular component movement GO:0051270 334 0.039
regulation of homeostatic process GO:0032844 121 0.039
response to virus GO:0009615 126 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.038
protein localization to membrane GO:0072657 160 0.037
regulation of antigen receptor mediated signaling pathway GO:0050854 10 0.037
release of sequestered calcium ion into cytosol GO:0051209 41 0.037
ras protein signal transduction GO:0007265 73 0.037
positive regulation of gtp catabolic process GO:0033126 166 0.036
extrinsic apoptotic signaling pathway GO:0097191 119 0.036
cytosolic calcium ion homeostasis GO:0051480 89 0.036
oogenesis GO:0048477 2 0.036
immune response regulating signaling pathway GO:0002764 97 0.036
negative regulation of transferase activity GO:0051348 124 0.036
positive regulation of cellular component movement GO:0051272 181 0.036
regulation of leukocyte activation GO:0002694 115 0.036
generation of neurons GO:0048699 152 0.036
purine ribonucleotide catabolic process GO:0009154 404 0.036
activation of protein kinase activity GO:0032147 90 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.035
positive regulation of t cell proliferation GO:0042102 33 0.035
positive regulation of dna metabolic process GO:0051054 73 0.035
negative regulation of programmed cell death GO:0043069 321 0.035
positive regulation of map kinase activity GO:0043406 80 0.035
negative regulation of immune system process GO:0002683 136 0.035
hemopoiesis GO:0030097 180 0.035
regulation of immunoglobulin production GO:0002637 4 0.035
calcium ion transport into cytosol GO:0060402 48 0.034
thymic t cell selection GO:0045061 2 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
cytosolic calcium ion transport GO:0060401 48 0.034
ribonucleoside catabolic process GO:0042454 406 0.034
cell development GO:0048468 328 0.034
nucleoside catabolic process GO:0009164 408 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
cellular chemical homeostasis GO:0055082 180 0.033
cell part morphogenesis GO:0032990 137 0.033
positive regulation of nucleotide catabolic process GO:0030813 185 0.033
establishment of protein localization to membrane GO:0090150 121 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
lymphocyte activation GO:0046649 133 0.032
positive regulation of cell proliferation GO:0008284 301 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
multicellular organismal aging GO:0010259 3 0.032
establishment of protein localization to plasma membrane GO:0090002 68 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
positive regulation of cell differentiation GO:0045597 211 0.031
response to external biotic stimulus GO:0043207 261 0.031
enzyme linked receptor protein signaling pathway GO:0007167 303 0.031
regulation of proteolysis GO:0030162 293 0.031
regulation of wnt signaling pathway GO:0030111 123 0.031
neurogenesis GO:0022008 169 0.030
plasma membrane organization GO:0007009 115 0.030
positive regulation of immunoglobulin production GO:0002639 4 0.030
regulation of cytokine mediated signaling pathway GO:0001959 41 0.030
negative regulation of kinase activity GO:0033673 106 0.030
behavior GO:0007610 112 0.030
Human Fly
locomotory behavior GO:0007626 1 0.030
Fly
heterotypic cell cell adhesion GO:0034113 28 0.030
cellular response to dna damage stimulus GO:0006974 379 0.030
Fly
mapk cascade GO:0000165 288 0.030
Human
isotype switching GO:0045190 3 0.030
regulation of protein autophosphorylation GO:0031952 15 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
negative regulation of growth GO:0045926 97 0.029
regulation of sequestering of calcium ion GO:0051282 41 0.029
osteoblast differentiation GO:0001649 92 0.029
Mouse
positive thymic t cell selection GO:0045059 1 0.028
positive regulation of t cell activation GO:0050870 54 0.028
defense response to other organism GO:0098542 129 0.028
regulation of protein serine threonine kinase activity GO:0071900 179 0.028
determination of adult lifespan GO:0008340 2 0.028
lipid metabolic process GO:0006629 381 0.028
bone development GO:0060348 26 0.027
response to ionizing radiation GO:0010212 65 0.027
regulation of gtpase activity GO:0043087 180 0.027
morphogenesis of embryonic epithelium GO:0016331 4 0.027
regulation of map kinase activity GO:0043405 108 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.027
hematopoietic progenitor cell differentiation GO:0002244 38 0.027
regulation of ras gtpase activity GO:0032318 128 0.027
regulation of phosphatase activity GO:0010921 81 0.027
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.027
regulation of ras protein signal transduction GO:0046578 155 0.027
leukocyte activation GO:0045321 164 0.027
transmembrane transport GO:0055085 399 0.027
positive regulation of gtpase activity GO:0043547 166 0.026
regulation of cytoskeleton organization GO:0051493 177 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
cell killing GO:0001906 34 0.026
regulation of small gtpase mediated signal transduction GO:0051056 156 0.026
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.026
cellular macromolecule catabolic process GO:0044265 380 0.025
protein processing GO:0016485 226 0.025
growth GO:0040007 202 0.025
regulation of secretion GO:0051046 194 0.025
memory GO:0007613 3 0.025
stem cell differentiation GO:0048863 93 0.025
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.025
protein localization to plasma membrane GO:0072659 93 0.025
positive regulation of lymphocyte activation GO:0051251 73 0.025
negative regulation of t cell mediated immunity GO:0002710 5 0.025
regulation of nervous system development GO:0051960 88 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
regulation of dephosphorylation GO:0035303 96 0.025
cardiovascular system development GO:0072358 262 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.024
circulatory system development GO:0072359 262 0.024
regulation of cell activation GO:0050865 125 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.024
mitotic cell cycle process GO:1903047 286 0.024
wound healing GO:0042060 115 0.024
response to biotic stimulus GO:0009607 276 0.024
regulation of immune response GO:0050776 201 0.024
neuron development GO:0048666 113 0.024
t cell activation GO:0042110 99 0.023
neuron projection development GO:0031175 106 0.023
mitotic cell cycle GO:0000278 326 0.023
adaptive immune response GO:0002250 49 0.023
endodermal cell differentiation GO:0035987 31 0.023
response to other organism GO:0051707 261 0.023
positive regulation of leukocyte activation GO:0002696 80 0.023
single organism cell adhesion GO:0098602 179 0.023
segmentation GO:0035282 4 0.023
negative regulation of transport GO:0051051 176 0.023
oocyte development GO:0048599 1 0.023
negative regulation of protein kinase activity GO:0006469 98 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.022
Mouse
regulation of dna recombination GO:0000018 23 0.022
regulation of cell cycle process GO:0010564 266 0.022
positive regulation of cell activation GO:0050867 81 0.022
ion transmembrane transport GO:0034220 338 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
cellular homeostasis GO:0019725 196 0.022
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.022
single organismal cell cell adhesion GO:0016337 148 0.022
cellular protein catabolic process GO:0044257 261 0.022
positive regulation of ras gtpase activity GO:0032320 117 0.022
regulation of protein localization GO:0032880 296 0.022
chromatin organization GO:0006325 351 0.022
positive regulation of locomotion GO:0040017 186 0.021
stem cell development GO:0048864 69 0.021
cellular lipid metabolic process GO:0044255 303 0.021
single organism cellular localization GO:1902580 332 0.021
regulation of lymphocyte activation GO:0051249 103 0.021
regulation of leukocyte proliferation GO:0070663 67 0.021
regulation of protein localization to plasma membrane GO:1903076 40 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
regulation of mononuclear cell proliferation GO:0032944 65 0.021
protein modification by small protein conjugation GO:0032446 342 0.021
t cell mediated immunity GO:0002456 25 0.021
negative regulation of cellular component movement GO:0051271 106 0.021
positive regulation of cytokine production GO:0001819 167 0.020
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.020
regeneration GO:0031099 4 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
Mouse
cell activation GO:0001775 213 0.020
cell substrate adhesion GO:0031589 132 0.020
protein maturation GO:0051604 233 0.020
regulation of isotype switching GO:0045191 2 0.020
microtubule based process GO:0007017 210 0.020
regulation of ion transport GO:0043269 189 0.020
ossification GO:0001503 121 0.020
tube morphogenesis GO:0035239 95 0.020
actin cytoskeleton organization GO:0030036 207 0.020
positive regulation of transport GO:0051050 336 0.020
endocytosis GO:0006897 159 0.020
histone modification GO:0016570 251 0.020
protein ubiquitination GO:0016567 314 0.020
mononuclear cell proliferation GO:0032943 71 0.020
neuron differentiation GO:0030182 138 0.019
carbohydrate metabolic process GO:0005975 207 0.019
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.019
cell projection morphogenesis GO:0048858 129 0.019
negative regulation of immune effector process GO:0002698 38 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.019
leukocyte differentiation GO:0002521 98 0.019
kidney development GO:0001822 53 0.019
protein catabolic process GO:0030163 325 0.019
membrane organization GO:0061024 292 0.019
blastoderm segmentation GO:0007350 2 0.019
regulation of immune effector process GO:0002697 91 0.018
actin filament organization GO:0007015 128 0.018
hindbrain development GO:0030902 3 0.018
regulation of peptidase activity GO:0052547 180 0.018
secretion GO:0046903 254 0.018
neurological system process GO:0050877 163 0.018
regulation of cellular response to growth factor stimulus GO:0090287 76 0.018
response to wounding GO:0009611 168 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
positive regulation of cell motility GO:2000147 177 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
leukocyte mediated immunity GO:0002443 59 0.018
actin filament based process GO:0030029 224 0.018
neuroblast proliferation GO:0007405 4 0.018
positive regulation of cell killing GO:0031343 19 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
positive regulation of cell development GO:0010720 92 0.017
regulation of cellular response to stress GO:0080135 244 0.017
Human Fly
associative learning GO:0008306 1 0.017
spermatid development GO:0007286 4 0.017
covalent chromatin modification GO:0016569 254 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
cell matrix adhesion GO:0007160 85 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
cellular response to abiotic stimulus GO:0071214 117 0.017
regulation of mitotic cell cycle GO:0007346 189 0.017
oxidation reduction process GO:0055114 396 0.017
regulation of cell adhesion GO:0030155 166 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
regulation of t cell proliferation GO:0042129 42 0.017
regulation of ion transmembrane transport GO:0034765 132 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
regulation of response to cytokine stimulus GO:0060759 46 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
regulation of binding GO:0051098 111 0.016
organelle assembly GO:0070925 176 0.016
secretion by cell GO:0032940 226 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
negative regulation of cell cycle GO:0045786 193 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.016
regulation of cell development GO:0060284 161 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
response to gamma radiation GO:0010332 14 0.016
muscle structure development GO:0061061 98 0.016
Human
regulation of protein processing GO:0070613 150 0.016
positive regulation of leukocyte mediated immunity GO:0002705 24 0.016
regulation of endocytosis GO:0030100 72 0.016
actin filament based movement GO:0030048 17 0.016
positive regulation of leukocyte proliferation GO:0070665 48 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.015
regulation of lymphocyte proliferation GO:0050670 64 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
reproductive process GO:0022414 106 0.015
humoral immune response GO:0006959 49 0.015
regulation of transmembrane transport GO:0034762 139 0.015
immune response activating signal transduction GO:0002757 90 0.015
positive regulation of immune response GO:0050778 159 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
negative regulation of apoptotic signaling pathway GO:2001234 97 0.015
positive regulation of t cell mediated immunity GO:0002711 12 0.015
atp metabolic process GO:0046034 176 0.015
positive regulation of synaptic transmission GO:0050806 4 0.015
adult locomotory behavior GO:0008344 1 0.015
Fly
regulation of production of molecular mediator of immune response GO:0002700 25 0.015
compound eye development GO:0048749 1 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
chromatin modification GO:0016568 298 0.015
lymphocyte differentiation GO:0030098 35 0.015
anterior posterior axis specification GO:0009948 2 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
regulation of protein transport GO:0051223 213 0.014
small molecule biosynthetic process GO:0044283 157 0.014
positive t cell selection GO:0043368 2 0.014
regulation of cell division GO:0051302 116 0.014
skin development GO:0043588 76 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
glycoprotein metabolic process GO:0009100 110 0.014
b cell proliferation GO:0042100 22 0.014
single organism reproductive process GO:0044702 98 0.014
rna processing GO:0006396 255 0.014
activation of immune response GO:0002253 114 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
endosomal transport GO:0016197 129 0.014
response to growth factor GO:0070848 205 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
ion homeostasis GO:0050801 230 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
peripheral nervous system development GO:0007422 2 0.014
epithelium development GO:0060429 227 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
neurotransmitter secretion GO:0007269 4 0.014
stem cell division GO:0017145 2 0.014
leukocyte cell cell adhesion GO:0007159 37 0.014
embryonic morphogenesis GO:0048598 85 0.014
leukocyte activation involved in immune response GO:0002366 30 0.014
regulation of cell killing GO:0031341 22 0.014
positive regulation of secretion by cell GO:1903532 108 0.014
regulation of growth GO:0040008 165 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
metencephalon development GO:0022037 2 0.013
somatic diversification of immune receptors GO:0002200 8 0.013
cytokine production GO:0001816 247 0.013
cation transmembrane transport GO:0098655 238 0.013
lymphocyte mediated immunity GO:0002449 48 0.013
digestive tract development GO:0048565 75 0.013
visual behavior GO:0007632 2 0.013
Fly
interspecies interaction between organisms GO:0044419 156 0.013
positive regulation of dna recombination GO:0045911 3 0.013
positive regulation of immune effector process GO:0002699 40 0.013
blood vessel development GO:0001568 172 0.013
regulation of response to external stimulus GO:0032101 222 0.013
Human
nucleoside monophosphate metabolic process GO:0009123 191 0.013
positive regulation of leukocyte differentiation GO:1902107 37 0.013
epithelial cell differentiation GO:0030855 141 0.013
intracellular protein transport GO:0006886 270 0.013
nephron development GO:0072006 30 0.013
t cell receptor signaling pathway GO:0050852 21 0.013
wnt signaling pathway GO:0016055 156 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of protein maturation GO:1903317 150 0.013
negative regulation of organelle organization GO:0010639 126 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
organelle fission GO:0048285 149 0.013
positive regulation of proteolysis GO:0045862 142 0.013
positive regulation of lymphocyte proliferation GO:0050671 46 0.013
cell fate determination GO:0001709 3 0.013
negative regulation of cell death GO:0060548 345 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
spermatid differentiation GO:0048515 4 0.013
heart development GO:0007507 95 0.012
glycoprotein biosynthetic process GO:0009101 91 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.012
neural tube formation GO:0001841 3 0.012
regulation of protein binding GO:0043393 66 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
positive regulation of organelle organization GO:0010638 195 0.012

SEMA4D disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.022
musculoskeletal system disease DOID:17 223 0.017
sensory system disease DOID:0050155 203 0.016
Human
nervous system disease DOID:863 431 0.016
Human
central nervous system disease DOID:331 186 0.016
eye and adnexa disease DOID:1492 150 0.015
Human
eye disease DOID:5614 149 0.015
Human
disease of cellular proliferation DOID:14566 174 0.015
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.014
inherited metabolic disorder DOID:655 242 0.014
cardiovascular system disease DOID:1287 106 0.013
neurodegenerative disease DOID:1289 102 0.012