Homo sapiens

119 known processes

SENP1

SUMO1/sentrin specific peptidase 1

(Aliases: SuPr-2)

SENP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein desumoylation GO:0016926 4 0.438
small gtpase mediated signal transduction GO:0007264 78 0.308
microtubule cytoskeleton organization GO:0000226 176 0.279
microtubule based process GO:0007017 210 0.269
protein import into nucleus GO:0006606 104 0.265
cellular response to dna damage stimulus GO:0006974 379 0.246
multicellular organismal aging GO:0010259 3 0.226
Worm
ribonucleoside triphosphate metabolic process GO:0009199 412 0.206
regulation of small gtpase mediated signal transduction GO:0051056 156 0.201
determination of adult lifespan GO:0008340 2 0.200
Worm
mitotic cell cycle process GO:1903047 286 0.194
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.193
positive regulation of nucleoside metabolic process GO:0045979 186 0.186
nucleocytoplasmic transport GO:0006913 176 0.171
dna conformation change GO:0071103 113 0.168
positive regulation of catabolic process GO:0009896 310 0.166
protein localization to organelle GO:0033365 280 0.165
intracellular protein transport GO:0006886 270 0.163
nuclear transport GO:0051169 179 0.162
central nervous system projection neuron axonogenesis GO:0021952 3 0.155
Fly
mrna metabolic process GO:0016071 175 0.154
cytoplasmic transport GO:0016482 379 0.139
protein targeting GO:0006605 187 0.135
ras protein signal transduction GO:0007265 73 0.133
positive regulation of protein phosphorylation GO:0001934 313 0.132
nucleoside triphosphate catabolic process GO:0009143 394 0.129
mitotic cell cycle GO:0000278 326 0.127
protein localization to nucleus GO:0034504 136 0.116
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.113
locomotory behavior GO:0007626 1 0.105
organophosphate catabolic process GO:0046434 430 0.101
nucleus organization GO:0006997 28 0.099
oxidation reduction process GO:0055114 396 0.094
embryo development GO:0009790 123 0.094
Worm
response to abiotic stimulus GO:0009628 336 0.092
Fly
chromatin organization GO:0006325 351 0.091
purine ribonucleoside metabolic process GO:0046128 437 0.090
nucleotide catabolic process GO:0009166 408 0.090
guanosine containing compound metabolic process GO:1901068 244 0.090
cardiac muscle cell contraction GO:0086003 4 0.088
regulation of ras protein signal transduction GO:0046578 155 0.084
ribonucleotide catabolic process GO:0009261 405 0.083
nucleoside triphosphate metabolic process GO:0009141 422 0.083
nucleoside catabolic process GO:0009164 408 0.082
purine nucleotide catabolic process GO:0006195 405 0.080
nuclear import GO:0051170 106 0.080
cellular macromolecule catabolic process GO:0044265 380 0.079
Mouse
regulation of transferase activity GO:0051338 355 0.078
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.078
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.077
Mouse
signal transduction by phosphorylation GO:0023014 297 0.077
glycosyl compound catabolic process GO:1901658 413 0.077
spindle organization GO:0007051 53 0.076
tricarboxylic acid cycle GO:0006099 4 0.075
regulation of kinase activity GO:0043549 314 0.075
single organism cellular localization GO:1902580 332 0.074
positive regulation of cellular catabolic process GO:0031331 284 0.074
cellular component morphogenesis GO:0032989 314 0.073
Fly
regulation of protein localization GO:0032880 296 0.073
Worm
purine containing compound catabolic process GO:0072523 411 0.073
purine nucleoside triphosphate metabolic process GO:0009144 412 0.072
dna damage checkpoint GO:0000077 68 0.072
establishment of protein localization to organelle GO:0072594 172 0.072
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.068
mitotic nuclear division GO:0007067 119 0.068
dendritic spine morphogenesis GO:0060997 3 0.064
Fly
female gamete generation GO:0007292 2 0.064
nucleoside phosphate catabolic process GO:1901292 412 0.063
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.061
regulation of protein kinase activity GO:0045859 289 0.061
central nervous system neuron axonogenesis GO:0021955 3 0.060
Fly
post embryonic development GO:0009791 2 0.059
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.058
anatomical structure homeostasis GO:0060249 100 0.058
protein sumoylation GO:0016925 25 0.057
protein targeting to nucleus GO:0044744 104 0.057
cell projection organization GO:0030030 252 0.057
Fly
protein modification by small protein removal GO:0070646 92 0.056
mitotic spindle organization GO:0007052 27 0.055
oogenesis GO:0048477 2 0.052
cell part morphogenesis GO:0032990 137 0.051
Fly
negative regulation of binding GO:0051100 57 0.051
regulation of protein serine threonine kinase activity GO:0071900 179 0.050
positive regulation of nucleotide catabolic process GO:0030813 185 0.049
regulation of gtpase activity GO:0043087 180 0.049
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.049
nuclear export GO:0051168 69 0.048
associative learning GO:0008306 1 0.048
gtp metabolic process GO:0046039 239 0.047
positive regulation of nucleotide metabolic process GO:0045981 230 0.047
single organism nuclear import GO:1902593 104 0.047
rhythmic behavior GO:0007622 2 0.047
nuclear division GO:0000280 128 0.045
pharynx development GO:0060465 1 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
positive regulation of map kinase activity GO:0043406 80 0.043
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.043
regulation of angiogenesis GO:0045765 92 0.043
mapk cascade GO:0000165 288 0.043
gtp catabolic process GO:0006184 237 0.042
positive regulation of transferase activity GO:0051347 227 0.042
regulation of nucleotide metabolic process GO:0006140 269 0.041
response to growth factor GO:0070848 205 0.041
negative regulation of locomotion GO:0040013 118 0.041
regulation of ras gtpase activity GO:0032318 128 0.040
mitotic sister chromatid segregation GO:0000070 53 0.040
protein catabolic process GO:0030163 325 0.039
Mouse
proteasomal protein catabolic process GO:0010498 176 0.039
Mouse
positive regulation of phosphorylation GO:0042327 394 0.038
negative regulation of cellular component movement GO:0051271 106 0.038
actin mediated cell contraction GO:0070252 12 0.038
membrane organization GO:0061024 292 0.038
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.038
purine nucleoside triphosphate catabolic process GO:0009146 392 0.037
rna phosphodiester bond hydrolysis GO:0090501 35 0.037
ribonucleoside catabolic process GO:0042454 406 0.037
negative regulation of epithelial cell migration GO:0010633 38 0.037
neuron differentiation GO:0030182 138 0.037
Fly
angiogenesis GO:0001525 147 0.036
organelle fission GO:0048285 149 0.036
nuclear body organization GO:0030575 4 0.036
dna repair GO:0006281 198 0.036
cell morphogenesis GO:0000902 296 0.036
Fly
ameboidal type cell migration GO:0001667 135 0.035
histone modification GO:0016570 251 0.035
regulation of nucleoside metabolic process GO:0009118 209 0.035
neurogenesis GO:0022008 169 0.035
Fly
negative regulation of cell migration GO:0030336 102 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
chromosome segregation GO:0007059 114 0.035
regulation of cytoplasmic transport GO:1903649 149 0.034
positive regulation of gtp catabolic process GO:0033126 166 0.034
modification dependent protein catabolic process GO:0019941 209 0.034
Mouse
actin filament based process GO:0030029 224 0.033
hemopoiesis GO:0030097 180 0.033
Mouse Fly
regulation of map kinase activity GO:0043405 108 0.033
striated muscle contraction GO:0006941 52 0.033
protein ubiquitination GO:0016567 314 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
regulation of proteasomal protein catabolic process GO:0061136 87 0.032
Mouse
tricarboxylic acid metabolic process GO:0072350 4 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
chromatin assembly or disassembly GO:0006333 78 0.032
meiotic chromosome segregation GO:0045132 4 0.031
maintenance of location GO:0051235 112 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
negative regulation of transport GO:0051051 176 0.030
regulation of cellular response to stress GO:0080135 244 0.030
chromatin modification GO:0016568 298 0.030
purine nucleoside catabolic process GO:0006152 398 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.029
macromolecule methylation GO:0043414 97 0.029
regulation of protein transport GO:0051223 213 0.029
regulation of intracellular protein transport GO:0033157 123 0.029
nervous system development GO:0007399 293 0.029
Fly
response to transforming growth factor beta GO:0071559 94 0.029
endomembrane system organization GO:0010256 196 0.028
regulation of purine nucleotide metabolic process GO:1900542 264 0.028
regulation of protein catabolic process GO:0042176 155 0.028
Mouse
cell projection morphogenesis GO:0048858 129 0.028
Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.027
endocytosis GO:0006897 159 0.027
pattern specification process GO:0007389 43 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
positive regulation of developmental process GO:0051094 314 0.027
regulation of proteolysis GO:0030162 293 0.027
cellular protein catabolic process GO:0044257 261 0.026
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.026
biological adhesion GO:0022610 331 0.026
regulation of cellular protein catabolic process GO:1903362 96 0.026
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.026
Fly
negative regulation of cellular component organization GO:0051129 235 0.025
ribonucleoprotein complex biogenesis GO:0022613 116 0.025
positive regulation of protein catabolic process GO:0045732 75 0.025
negative regulation of cytoplasmic transport GO:1903650 46 0.025
cardiac muscle contraction GO:0060048 34 0.025
regulation of nucleocytoplasmic transport GO:0046822 98 0.025
blood vessel development GO:0001568 172 0.024
positive regulation of kinase activity GO:0033674 204 0.024
regulation of mapk cascade GO:0043408 262 0.024
regulation of gtp catabolic process GO:0033124 180 0.024
chemical homeostasis GO:0048878 306 0.024
cardiovascular system development GO:0072358 262 0.023
positive regulation of transport GO:0051050 336 0.023
dna packaging GO:0006323 77 0.023
neuroblast proliferation GO:0007405 4 0.023
dendritic spine organization GO:0097061 4 0.023
Fly
generation of precursor metabolites and energy GO:0006091 68 0.022
protein modification by small protein conjugation GO:0032446 342 0.022
somitogenesis GO:0001756 2 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.022
Mouse
cellular response to endogenous stimulus GO:0071495 336 0.022
positive regulation of gtpase activity GO:0043547 166 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
peripheral nervous system development GO:0007422 2 0.021
rna processing GO:0006396 255 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
Mouse
central nervous system development GO:0007417 123 0.021
Fly
fas signaling pathway GO:0036337 3 0.021
actin filament based movement GO:0030048 17 0.021
cell cycle phase transition GO:0044770 173 0.021
response to ionizing radiation GO:0010212 65 0.021
response to biotic stimulus GO:0009607 276 0.021
protein import GO:0017038 130 0.021
generation of neurons GO:0048699 152 0.020
Fly
positive regulation of ras gtpase activity GO:0032320 117 0.020
secretion GO:0046903 254 0.020
central nervous system neuron development GO:0021954 7 0.020
Fly
positive regulation of cellular component organization GO:0051130 376 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.020
Mouse
cellular amino acid metabolic process GO:0006520 116 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
regulation of cellular ketone metabolic process GO:0010565 50 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.020
Fly
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
inorganic ion transmembrane transport GO:0098660 231 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
cation transport GO:0006812 331 0.019
inorganic cation transmembrane transport GO:0098662 194 0.019
multicellular organismal signaling GO:0035637 34 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
mrna processing GO:0006397 133 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.019
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
cation transmembrane transport GO:0098655 238 0.018
regulation of cell motility GO:2000145 299 0.018
divalent metal ion transport GO:0070838 152 0.018
cellular homeostasis GO:0019725 196 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
vesicle mediated transport GO:0016192 371 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
aging GO:0007568 66 0.018
Worm
covalent chromatin modification GO:0016569 254 0.018
response to external biotic stimulus GO:0043207 261 0.018
negative regulation of dna binding GO:0043392 18 0.018
neuron development GO:0048666 113 0.018
Fly
cell development GO:0048468 328 0.017
Fly
tissue migration GO:0090130 119 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
circadian behavior GO:0048512 2 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
cellular chemical homeostasis GO:0055082 180 0.017
negative regulation of intracellular protein transport GO:0090317 42 0.017
negative regulation of intracellular transport GO:0032387 60 0.017
sister chromatid segregation GO:0000819 54 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
spermatid differentiation GO:0048515 4 0.017
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.016
epithelium migration GO:0090132 119 0.016
carbohydrate metabolic process GO:0005975 207 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
histone methylation GO:0016571 60 0.016
regulation of system process GO:0044057 101 0.016
protein methylation GO:0006479 74 0.016
heart contraction GO:0060047 62 0.016
negative regulation of protein modification process GO:0031400 200 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
regulation of intracellular transport GO:0032386 195 0.016
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.016
digestive system development GO:0055123 75 0.016
embryonic placenta development GO:0001892 1 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.015
transmembrane transport GO:0055085 399 0.015
regulation of cell migration GO:0030334 289 0.015
visual behavior GO:0007632 2 0.015
ossification GO:0001503 121 0.015
autophagic cell death GO:0048102 3 0.015
double strand break repair GO:0006302 101 0.015
positive regulation of cellular protein catabolic process GO:1903364 37 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
regulation of gene silencing GO:0060968 24 0.015
tube development GO:0035295 125 0.015
epithelium development GO:0060429 227 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
response to other organism GO:0051707 261 0.014
innate immune response GO:0045087 178 0.014
response to salt stress GO:0009651 3 0.014
ribose phosphate biosynthetic process GO:0046390 82 0.014
regulation of cellular amino acid metabolic process GO:0006521 6 0.014
regulation of binding GO:0051098 111 0.014
oocyte development GO:0048599 1 0.014
protein export from nucleus GO:0006611 29 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.013
muscle contraction GO:0006936 73 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
centrosome organization GO:0051297 58 0.013
positive regulation of apoptotic signaling pathway GO:2001235 70 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
Mouse Fly
rna splicing GO:0008380 131 0.013
positive regulation of proteolysis GO:0045862 142 0.013
regulation of cellular component movement GO:0051270 334 0.013
endothelial cell migration GO:0043542 86 0.013
metal ion transport GO:0030001 272 0.013
negative regulation of cell death GO:0060548 345 0.013
regulation of dna binding GO:0051101 37 0.013
atp metabolic process GO:0046034 176 0.013
adult locomotory behavior GO:0008344 1 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
Mouse
blood circulation GO:0008015 113 0.013
rna interference GO:0016246 4 0.013
blood vessel morphogenesis GO:0048514 162 0.013
segmentation GO:0035282 4 0.013
regulation of muscle contraction GO:0006937 45 0.013
definitive hemopoiesis GO:0060216 2 0.013
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.012
mitochondrion organization GO:0007005 156 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
regulation of cell development GO:0060284 161 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
response to fungus GO:0009620 4 0.012
dephosphorylation GO:0016311 209 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.012
response to oxidative stress GO:0006979 121 0.012
axonogenesis GO:0007409 31 0.012
Fly
negative regulation of cell motility GO:2000146 104 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
response to hypoxia GO:0001666 96 0.012
Fly
head development GO:0060322 108 0.012
circulatory system development GO:0072359 262 0.012
regulation of protein targeting GO:1903533 91 0.012
neuron projection morphogenesis GO:0048812 50 0.012
Fly
neural crest cell development GO:0014032 3 0.012
regulation of actin filament based process GO:0032970 141 0.012
system process GO:0003008 349 0.012
secretion by cell GO:0032940 226 0.012
lipid storage GO:0019915 28 0.012
positive regulation of programmed cell death GO:0043068 249 0.011
cellular respiration GO:0045333 21 0.011
response to oxygen containing compound GO:1901700 369 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
spermatid development GO:0007286 4 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
phagocytosis GO:0006909 42 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
smad protein import into nucleus GO:0007184 13 0.011
regulation of cell differentiation GO:0045595 393 0.011
Mouse Fly
short term memory GO:0007614 1 0.011
regulation of body fluid levels GO:0050878 99 0.011
positive regulation of neural precursor cell proliferation GO:2000179 2 0.011
regulation of immune response GO:0050776 201 0.011
heart process GO:0003015 62 0.011
negative regulation of protein transport GO:0051224 75 0.011
defense response to fungus GO:0050832 4 0.011
embryo development ending in birth or egg hatching GO:0009792 34 0.011
Worm
regulation of apoptotic signaling pathway GO:2001233 175 0.011
glucose homeostasis GO:0042593 31 0.011
positive regulation of protein ubiquitination GO:0031398 53 0.011
regulation of blood circulation GO:1903522 59 0.011
wnt signaling pathway GO:0016055 156 0.011
positive regulation of defense response GO:0031349 87 0.011
compound eye development GO:0048749 1 0.011
dna recombination GO:0006310 77 0.011
cell adhesion GO:0007155 325 0.010
regulation of metal ion transport GO:0010959 120 0.010
amine metabolic process GO:0009308 44 0.010
cellular ketone metabolic process GO:0042180 80 0.010
cilium morphogenesis GO:0060271 75 0.010
osteoblast differentiation GO:0001649 92 0.010
cellular protein complex assembly GO:0043623 188 0.010
negative regulation of developmental process GO:0051093 247 0.010
Fly
organelle localization GO:0051640 84 0.010
response to hormone GO:0009725 175 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
immune response GO:0006955 307 0.010
embryonic camera type eye development GO:0031076 2 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
regulation of muscle cell differentiation GO:0051147 31 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010

SENP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.028
eye and adnexa disease DOID:1492 150 0.028
nervous system disease DOID:863 431 0.028
physical disorder DOID:0080015 41 0.013
central nervous system disease DOID:331 186 0.012
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010
organ system cancer DOID:0050686 164 0.010