Homo sapiens

24 known processes

SF3A1

splicing factor 3a, subunit 1, 120kDa

(Aliases: SAP114,PRP21,PRPF21,SF3A120)

SF3A1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna processing GO:0006397 133 0.989
rna processing GO:0006396 255 0.986
regulation of meiotic cell cycle GO:0051445 4 0.980
Worm
mrna metabolic process GO:0016071 175 0.969
mrna splicing via spliceosome GO:0000398 89 0.961
cell development GO:0048468 328 0.855
Worm
hematopoietic stem cell differentiation GO:0060218 4 0.842
positive regulation of nfat protein import into nucleus GO:0051533 3 0.766
regulation of cell cycle GO:0051726 393 0.712
Worm
mitotic cell cycle GO:0000278 326 0.666
Fly
spliceosomal snrnp assembly GO:0000387 28 0.633
positive regulation of intracellular protein transport GO:0090316 76 0.538
immune system development GO:0002520 195 0.496
post embryonic development GO:0009791 2 0.425
regulation of protein transport GO:0051223 213 0.403
positive regulation of cytoplasmic transport GO:1903651 82 0.401
positive regulation of protein localization to nucleus GO:1900182 48 0.361
cell division GO:0051301 168 0.351
Worm
regulation of protein localization to nucleus GO:1900180 85 0.327
oogenesis GO:0048477 2 0.316
regulation of meiosis GO:0040020 3 0.314
Worm
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.313
mitotic cell cycle process GO:1903047 286 0.312
Fly
regulation of nuclear division GO:0051783 65 0.300
Worm
spindle organization GO:0007051 53 0.291
Fly
establishment of protein localization to organelle GO:0072594 172 0.243
positive regulation of transcription factor import into nucleus GO:0042993 25 0.234
myosin filament assembly GO:0031034 2 0.191
hematopoietic progenitor cell differentiation GO:0002244 38 0.187
protein import GO:0017038 130 0.184
nfat protein import into nucleus GO:0051531 5 0.183
positive regulation of protein import into nucleus GO:0042307 46 0.179
proteasomal protein catabolic process GO:0010498 176 0.178
regulation of astrocyte differentiation GO:0048710 3 0.168
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.165
positive regulation of intracellular transport GO:0032388 104 0.162
embryo development GO:0009790 123 0.160
Worm
blastoderm segmentation GO:0007350 2 0.155
regulation of cell cycle process GO:0010564 266 0.152
Worm
cellular response to dna damage stimulus GO:0006974 379 0.150
regulation of intracellular transport GO:0032386 195 0.150
sex determination GO:0007530 3 0.149
blastocyst development GO:0001824 3 0.141
regulation of cellular response to stress GO:0080135 244 0.140
microtubule based process GO:0007017 210 0.135
Fly
positive regulation of protein transport GO:0051222 135 0.131
oocyte development GO:0048599 1 0.128
intracellular protein transport GO:0006886 270 0.126
nucleocytoplasmic transport GO:0006913 176 0.126
stem cell differentiation GO:0048863 93 0.123
meiotic cell cycle GO:0051321 13 0.121
Worm
nervous system development GO:0007399 293 0.121
female gamete generation GO:0007292 2 0.120
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.119
regulation of protein localization GO:0032880 296 0.118
protein targeting to nucleus GO:0044744 104 0.117
regulation of protein import into nucleus GO:0042306 78 0.117
positive regulation of transport GO:0051050 336 0.114
cytoplasmic transport GO:0016482 379 0.114
neurogenesis GO:0022008 169 0.114
rna splicing via transesterification reactions GO:0000375 90 0.111
nuclear division GO:0000280 128 0.111
Worm Fly
small gtpase mediated signal transduction GO:0007264 78 0.111
regulation of cytoplasmic transport GO:1903649 149 0.102
protein localization to organelle GO:0033365 280 0.099
transcription factor import into nucleus GO:0042991 40 0.099
anterior posterior axis specification embryo GO:0008595 2 0.097
molting cycle GO:0042303 28 0.089
reproductive structure development GO:0048608 55 0.088
Worm
actin filament based process GO:0030029 224 0.087
positive regulation of mrna processing GO:0050685 17 0.087
reproductive system development GO:0061458 56 0.085
Worm
protein targeting GO:0006605 187 0.082
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.078
negative regulation of protein metabolic process GO:0051248 391 0.078
protein import into nucleus GO:0006606 104 0.077
regulation of nucleocytoplasmic transport GO:0046822 98 0.076
lipid metabolic process GO:0006629 381 0.076
single organism cellular localization GO:1902580 332 0.075
regulation of small gtpase mediated signal transduction GO:0051056 156 0.074
oocyte differentiation GO:0009994 2 0.073
hematopoietic or lymphoid organ development GO:0048534 186 0.071
regulation of protein targeting GO:1903533 91 0.070
cellular response to organic cyclic compound GO:0071407 127 0.068
cellular macromolecular complex assembly GO:0034622 324 0.066
determination of adult lifespan GO:0008340 2 0.066
single organism nuclear import GO:1902593 104 0.066
meiosis i GO:0007127 4 0.065
protein ubiquitination GO:0016567 314 0.064
regulation of transcription factor import into nucleus GO:0042990 39 0.062
anterior posterior axis specification GO:0009948 2 0.061
regulation of cell cycle phase transition GO:1901987 126 0.060
organelle assembly GO:0070925 176 0.059
tripartite regional subdivision GO:0007351 2 0.058
lipid biosynthetic process GO:0008610 177 0.057
ribonucleoprotein complex assembly GO:0022618 78 0.056
regulation of intracellular protein transport GO:0033157 123 0.056
cell cycle phase transition GO:0044770 173 0.055
cellular response to histamine GO:0071420 3 0.054
nuclear transport GO:0051169 179 0.054
positive regulation of developmental process GO:0051094 314 0.053
histone modification GO:0016570 251 0.053
ribonucleoprotein complex subunit organization GO:0071826 81 0.051
regulation of cell differentiation GO:0045595 393 0.051
ras protein signal transduction GO:0007265 73 0.051
regulation of ras protein signal transduction GO:0046578 155 0.050
actin cytoskeleton organization GO:0030036 207 0.048
negative regulation of programmed cell death GO:0043069 321 0.048
posttranscriptional gene silencing by rna GO:0035194 25 0.048
Worm
regulation of glial cell differentiation GO:0045685 3 0.047
striated muscle myosin thick filament assembly GO:0071688 2 0.047
autophagy GO:0006914 88 0.046
nuclear import GO:0051170 106 0.046
positive regulation of mapk cascade GO:0043410 190 0.046
organelle fission GO:0048285 149 0.044
Worm Fly
cellular component morphogenesis GO:0032989 314 0.044
double strand break repair GO:0006302 101 0.043
signal transduction by p53 class mediator GO:0072331 72 0.042
development of primary sexual characteristics GO:0045137 35 0.041
Worm
multicellular organismal reproductive process GO:0048609 40 0.040
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.039
embryo development ending in birth or egg hatching GO:0009792 34 0.039
Worm
mitotic cell cycle phase transition GO:0044772 162 0.039
positive regulation of programmed cell death GO:0043068 249 0.038
chordate embryonic development GO:0043009 34 0.038
erk1 and erk2 cascade GO:0070371 104 0.037
gene silencing GO:0016458 49 0.037
Worm
microtubule cytoskeleton organization GO:0000226 176 0.036
Fly
neuron differentiation GO:0030182 138 0.035
cellular macromolecule catabolic process GO:0044265 380 0.034
astrocyte differentiation GO:0048708 4 0.034
positive regulation of cell differentiation GO:0045597 211 0.034
signal transduction in response to dna damage GO:0042770 57 0.031
regulation of neurogenesis GO:0050767 82 0.031
cellular protein complex assembly GO:0043623 188 0.031
mitotic nuclear division GO:0007067 119 0.030
Fly
negative regulation of cell death GO:0060548 345 0.030
positive regulation of cell proliferation GO:0008284 301 0.030
intracellular mrna localization GO:0008298 1 0.030
regulation of cell activation GO:0050865 125 0.030
reproductive process GO:0022414 106 0.030
Worm
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 20 0.030
sex differentiation GO:0007548 45 0.029
Worm
negative regulation of multicellular organismal process GO:0051241 317 0.029
response to organic cyclic compound GO:0014070 204 0.028
regulation of cellular component movement GO:0051270 334 0.028
cellular component disassembly GO:0022411 92 0.028
vesicle mediated transport GO:0016192 371 0.028
Worm
mapk cascade GO:0000165 288 0.028
positive regulation of immune system process GO:0002684 283 0.028
protein catabolic process GO:0030163 325 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
multi organism reproductive process GO:0044703 54 0.026
Worm
regulation of mrna splicing via spliceosome GO:0048024 32 0.026
Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.024
regulation of signal transduction by p53 class mediator GO:1901796 26 0.024
positive regulation of cell death GO:0010942 263 0.023
rna splicing GO:0008380 131 0.023
protein localization to nucleus GO:0034504 136 0.022
mitotic cell cycle checkpoint GO:0007093 68 0.022
negative regulation of developmental process GO:0051093 247 0.022
cellular protein catabolic process GO:0044257 261 0.022
covalent chromatin modification GO:0016569 254 0.021
response to light stimulus GO:0009416 87 0.021
locomotory behavior GO:0007626 1 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
protein polyubiquitination GO:0000209 110 0.020
histone h3 acetylation GO:0043966 45 0.020
muscle structure development GO:0061061 98 0.020
g1 s transition of mitotic cell cycle GO:0000082 78 0.020
negative regulation of mitotic cell cycle GO:0045930 102 0.019
negative regulation of response to dna damage stimulus GO:2001021 33 0.018
actin mediated cell contraction GO:0070252 12 0.018
wnt signaling pathway GO:0016055 156 0.018
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.018
regulation of mitotic cell cycle GO:0007346 189 0.018
rrna processing GO:0006364 35 0.018
positive regulation of glial cell differentiation GO:0045687 2 0.017
regulation of rna splicing GO:0043484 62 0.017
Fly
maintenance of location GO:0051235 112 0.017
positive regulation of gliogenesis GO:0014015 4 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
single organism reproductive process GO:0044702 98 0.016
Worm
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
metal ion transport GO:0030001 272 0.016
compound eye development GO:0048749 1 0.016
developmental process involved in reproduction GO:0003006 66 0.016
Worm
positive regulation of mrna metabolic process GO:1903313 19 0.016
protein acetylation GO:0006473 116 0.016
muscle cell differentiation GO:0042692 63 0.016
growth GO:0040007 202 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
defense response GO:0006952 315 0.016
fertilization GO:0009566 12 0.016
negative regulation of cell differentiation GO:0045596 171 0.016
response to hypoxia GO:0001666 96 0.015
chromatin organization GO:0006325 351 0.015
regulation of neuron differentiation GO:0045664 70 0.015
regulation of autophagy GO:0010506 52 0.015
response to radiation GO:0009314 151 0.015
mrna stabilization GO:0048255 18 0.015
response to fungus GO:0009620 4 0.015
regulation of cell division GO:0051302 116 0.015
Worm
dna packaging GO:0006323 77 0.015
regulation of mapk cascade GO:0043408 262 0.015
chromatin modification GO:0016568 298 0.015
actin polymerization or depolymerization GO:0008154 56 0.015
cell morphogenesis GO:0000902 296 0.014
generation of neurons GO:0048699 152 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
positive regulation of ras protein signal transduction GO:0046579 12 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.014
cellular divalent inorganic cation homeostasis GO:0072503 128 0.014
circadian behavior GO:0048512 2 0.014
hemopoiesis GO:0030097 180 0.014
rhythmic behavior GO:0007622 2 0.014
actin filament based movement GO:0030048 17 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
reproduction GO:0000003 63 0.013
Worm
dna repair GO:0006281 198 0.013
neuron projection development GO:0031175 106 0.013
mitotic spindle organization GO:0007052 27 0.013
Fly
epithelium development GO:0060429 227 0.013
sexual reproduction GO:0019953 37 0.013
Worm
gene silencing by rna GO:0031047 26 0.012
Worm
memory GO:0007613 3 0.012
protein k63 linked ubiquitination GO:0070534 31 0.012
ribonucleoprotein complex biogenesis GO:0022613 116 0.012
regulation of actin filament based process GO:0032970 141 0.012
negative regulation of locomotion GO:0040013 118 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
regulation of proteolysis GO:0030162 293 0.012
regulation of cell cycle g1 s phase transition GO:1902806 42 0.012
meiotic nuclear division GO:0007126 10 0.012
Worm
striated muscle cell differentiation GO:0051146 43 0.012
regulation of mrna processing GO:0050684 48 0.012
Fly
negative regulation of neuron differentiation GO:0045665 21 0.011
actomyosin structure organization GO:0031032 59 0.011
regulation of metal ion transport GO:0010959 120 0.011
positive regulation of rna splicing GO:0033120 12 0.011
multicellular organism reproduction GO:0032504 42 0.011
Worm
photoreceptor cell differentiation GO:0046530 2 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
circulatory system development GO:0072359 262 0.011
regulation of calcium ion transport GO:0051924 79 0.011
myeloid cell differentiation GO:0030099 117 0.011
associative learning GO:0008306 1 0.011
muscle cell development GO:0055001 29 0.010
cellular response to ammonium ion GO:0071242 4 0.010
protein dephosphorylation GO:0006470 81 0.010
non recombinational repair GO:0000726 14 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010

SF3A1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.085
nervous system disease DOID:863 431 0.085
disease of cellular proliferation DOID:14566 174 0.042
cancer DOID:162 167 0.033
organ system cancer DOID:0050686 164 0.033
auditory system disease DOID:2742 53 0.024
nonsyndromic deafness DOID:0050563 50 0.024