|
|
epithelium development
|
GO:0060429 |
227 |
1.000
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
Yeast Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
1.000
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
1.000
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
1.000
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
1.000
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
1.000
|
Yeast Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
1.000
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.999
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.999
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.999
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.999
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.999
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.998
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.998
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.998
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.997
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.997
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.997
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.996
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.996
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.996
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.996
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.996
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.996
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.995
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.994
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.993
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.992
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.992
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.992
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.992
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.990
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.990
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.990
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.989
|
Mouse |
|
|
action potential
|
GO:0001508 |
34 |
0.987
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.987
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.986
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.986
|
Yeast |
|
|
cell development
|
GO:0048468 |
328 |
0.986
|
Human Yeast Mouse Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.986
|
Mouse |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.984
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.983
|
Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.983
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.982
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.981
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.981
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.980
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.980
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.979
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.978
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.977
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.976
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.975
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.975
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.975
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.974
|
Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.973
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.973
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.973
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.972
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.972
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.972
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.971
|
Fly |
|
|
skin development
|
GO:0043588 |
76 |
0.971
|
Mouse |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.970
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.968
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.965
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.964
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.961
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.961
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.960
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.960
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.960
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.957
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.957
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.956
|
Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.954
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.953
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.948
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.947
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.945
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.943
|
Human |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.941
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.940
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.938
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.936
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.936
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.936
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.934
|
Yeast Mouse |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.933
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.933
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.931
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.931
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.930
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.929
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.927
|
Fly |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.926
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.920
|
Yeast Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.918
|
Human Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.912
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.908
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.906
|
Human Yeast |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.904
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.904
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.898
|
Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.898
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.894
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.887
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.886
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.882
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.881
|
Human |
|
|
epidermis development
|
GO:0008544 |
59 |
0.881
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.880
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.879
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.877
|
|
|
|
desmosome assembly
|
GO:0002159 |
4 |
0.875
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.869
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.869
|
|
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.867
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.866
|
Yeast Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.866
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.865
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.853
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.845
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.845
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.842
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.842
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.841
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.840
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.836
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.834
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.834
|
Human Mouse |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.832
|
Human |
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.828
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.825
|
Mouse |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.815
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.811
|
Human Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.810
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.808
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.806
|
Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.797
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.797
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.794
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.794
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.793
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.787
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.780
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.770
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.760
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.756
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.752
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.751
|
Fly |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.750
|
Yeast |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.742
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.737
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.735
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.733
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.731
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.729
|
Mouse |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.726
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.724
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.723
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.719
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.718
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.711
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.690
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.689
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.686
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.682
|
Fly |
|
|
skin morphogenesis
|
GO:0043589 |
6 |
0.681
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.667
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.666
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.664
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.664
|
Mouse |
|
|
regulation of actin filament based movement
|
GO:1903115 |
24 |
0.662
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.660
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.660
|
Yeast |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.657
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.648
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.635
|
Yeast Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.632
|
Yeast |
|
|
tissue migration
|
GO:0090130 |
119 |
0.625
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.625
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.623
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.622
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.611
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.610
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.598
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.588
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.577
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.576
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.574
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.573
|
|
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.565
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.564
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.563
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.549
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.544
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.544
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.544
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.543
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.541
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.539
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.535
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.534
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.525
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.524
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.524
|
Yeast Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.519
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.519
|
Mouse |
|
|
bundle of his cell to purkinje myocyte communication
|
GO:0086069 |
8 |
0.512
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.510
|
Yeast |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.508
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.496
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.490
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.487
|
Yeast |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.483
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.472
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.460
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.459
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.458
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.452
|
Mouse |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.450
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.444
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.442
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.441
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.441
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.438
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.436
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.436
|
Human Mouse |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.434
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.420
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.417
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.415
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.413
|
Human |
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.404
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.388
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.385
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.385
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.384
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.382
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.381
|
Yeast |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.379
|
Fly |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.367
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.360
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
14 |
0.359
|
|
|
|
lung vasculature development
|
GO:0060426 |
2 |
0.353
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.353
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.351
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.351
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.350
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.346
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.344
|
|
|
|
regulation of heart rate by cardiac conduction
|
GO:0086091 |
19 |
0.341
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.340
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.340
|
Human |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.337
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.336
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.334
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.326
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.324
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.324
|
Yeast |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.323
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.323
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.323
|
|
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.322
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.322
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.316
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.315
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.314
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.313
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.312
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.306
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.305
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.297
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.289
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.287
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.284
|
Human |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.278
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.275
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.274
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.269
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.266
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.266
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.262
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.261
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.261
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.260
|
|
|
|
membrane depolarization during action potential
|
GO:0086010 |
10 |
0.258
|
Human |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.258
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.256
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.255
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.255
|
|
|
|
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0016339 |
2 |
0.253
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.251
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.250
|
Yeast |
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.247
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.243
|
Yeast |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.242
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.241
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.239
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.233
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.233
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.232
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.231
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.229
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.227
|
Human |
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.225
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.224
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.222
|
|
|
|
growth
|
GO:0040007 |
202 |
0.220
|
Yeast Mouse |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.220
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.218
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.216
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.215
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.213
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.211
|
Yeast |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.210
|
Yeast |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.210
|
Yeast |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.208
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.208
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.204
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.201
|
Fly |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.201
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.200
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.199
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.198
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.197
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.195
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.193
|
Human |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.190
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.190
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.189
|
|
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
0.189
|
Human |
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
17 |
0.188
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.188
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.188
|
Human |
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.188
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.183
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.183
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.182
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.182
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.181
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.180
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.179
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.179
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.178
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.172
|
Human |
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.170
|
Human |
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
18 |
0.170
|
|
|
|
regulation of anoikis
|
GO:2000209 |
19 |
0.170
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.169
|
Yeast |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.169
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.168
|
|
|
|
pulmonary valve formation
|
GO:0003193 |
1 |
0.168
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.167
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.166
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.166
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.166
|
Fly |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.163
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.160
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.159
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.158
|
|
|
|
desmosome organization
|
GO:0002934 |
5 |
0.158
|
|
|
|
positive regulation of anoikis
|
GO:2000210 |
4 |
0.158
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.156
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.154
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.153
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.152
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.152
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.150
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.150
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.149
|
Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.148
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.148
|
Mouse |
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.147
|
Mouse |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.146
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.145
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.145
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.143
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.142
|
|
|
|
av node cell to bundle of his cell communication
|
GO:0086067 |
4 |
0.142
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.140
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.140
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.139
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.138
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.137
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.137
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.136
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.134
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.134
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.133
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.132
|
|
|
|
cell communication involved in cardiac conduction
|
GO:0086065 |
18 |
0.132
|
|
|
|
apical junction assembly
|
GO:0043297 |
19 |
0.131
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.131
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.130
|
Yeast |
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.129
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.128
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.128
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.127
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.127
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.127
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.126
|
Mouse |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.126
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.126
|
|
|
|
cell communication by electrical coupling involved in cardiac conduction
|
GO:0086064 |
3 |
0.125
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.123
|
Mouse |
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.123
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.123
|
Mouse |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.122
|
Yeast |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.122
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.118
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.117
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.116
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.116
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.116
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.116
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.116
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.115
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.115
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.113
|
Yeast |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.110
|
Yeast |
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.110
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.110
|
Yeast Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.110
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.110
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.110
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.109
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.109
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.109
|
Yeast |
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
30 |
0.109
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.107
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.107
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.106
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.104
|
Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.104
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.103
|
Mouse |
|
|
regulation of keratinocyte differentiation
|
GO:0045616 |
11 |
0.102
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.100
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.100
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.099
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.098
|
Human |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.097
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.097
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.096
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.095
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.095
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.095
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.095
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.092
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.091
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.090
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
0.090
|
Yeast |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.090
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.089
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.088
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.087
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.087
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.087
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.087
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.086
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.086
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.086
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.085
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.085
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.084
|
Yeast Fly |
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.084
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.084
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.084
|
Yeast |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.084
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.083
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.083
|
Yeast Fly |
|
|
muscle organ development
|
GO:0007517 |
56 |
0.083
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.083
|
Human |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.083
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.082
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.081
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.081
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.081
|
Mouse |
|
|
maintenance of organ identity
|
GO:0048496 |
5 |
0.080
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.079
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.079
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.078
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.078
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.078
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.078
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.076
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.076
|
|
|
|
system process
|
GO:0003008 |
349 |
0.076
|
Fly |
|
|
histone modification
|
GO:0016570 |
251 |
0.075
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.075
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.075
|
|
