Homo sapiens

181 known processes

SFRP4

secreted frizzled-related protein 4

(Aliases: FRPHE,MGC26498,FRP-4)

SFRP4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell migration GO:0030334 289 0.675
cellular response to endogenous stimulus GO:0071495 336 0.647
regulation of locomotion GO:0040012 329 0.512
positive regulation of locomotion GO:0040017 186 0.460
cellular response to growth factor stimulus GO:0071363 197 0.459
cellular ketone metabolic process GO:0042180 80 0.424
enzyme linked receptor protein signaling pathway GO:0007167 303 0.416
response to growth factor GO:0070848 205 0.392
regulation of cellular component movement GO:0051270 334 0.375
regulation of cell motility GO:2000145 299 0.333
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.302
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.301
anatomical structure formation involved in morphogenesis GO:0048646 284 0.299
Human
connective tissue development GO:0061448 39 0.298
skeletal system development GO:0001501 79 0.293
negative regulation of multicellular organismal process GO:0051241 317 0.293
Human
vasculature development GO:0001944 181 0.293
Human
blood vessel morphogenesis GO:0048514 162 0.291
regulation of cellular amine metabolic process GO:0033238 11 0.279
positive regulation of cellular component movement GO:0051272 181 0.269
amine metabolic process GO:0009308 44 0.269
positive regulation of cell motility GO:2000147 177 0.262
negative regulation of locomotion GO:0040013 118 0.256
tube development GO:0035295 125 0.255
Human
response to oxygen containing compound GO:1901700 369 0.250
Rat
positive regulation of cellular amine metabolic process GO:0033240 7 0.235
negative regulation of developmental process GO:0051093 247 0.233
Human
regulation of cell adhesion GO:0030155 166 0.231
Human
negative regulation of cell migration GO:0030336 102 0.231
positive regulation of developmental process GO:0051094 314 0.218
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.203
negative regulation of epithelial cell migration GO:0010633 38 0.200
positive regulation of cell migration GO:0030335 172 0.197
regulation of angiogenesis GO:0045765 92 0.196
extracellular matrix organization GO:0030198 41 0.196
response to transforming growth factor beta GO:0071559 94 0.195
regulation of cellular amino acid metabolic process GO:0006521 6 0.183
regulation of cellular ketone metabolic process GO:0010565 50 0.180
negative regulation of cell motility GO:2000146 104 0.174
cardiovascular system development GO:0072358 262 0.169
Human
wound healing GO:0042060 115 0.169
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.167
Human
tissue morphogenesis GO:0048729 96 0.162
positive regulation of protein phosphorylation GO:0001934 313 0.160
Human
regulation of epithelial cell proliferation GO:0050678 113 0.160
Human
regulation of cell differentiation GO:0045595 393 0.157
response to wounding GO:0009611 168 0.153
Human
circulatory system development GO:0072359 262 0.152
Human
positive regulation of cell proliferation GO:0008284 301 0.151
Human
cellular amino acid metabolic process GO:0006520 116 0.150
angiogenesis GO:0001525 147 0.149
positive regulation of cellular component organization GO:0051130 376 0.145
regulation of protein kinase activity GO:0045859 289 0.139
Human
blood vessel development GO:0001568 172 0.138
positive regulation of cell death GO:0010942 263 0.137
regulation of transferase activity GO:0051338 355 0.130
Human
regulation of stem cell differentiation GO:2000736 56 0.130
cellular amine metabolic process GO:0044106 41 0.129
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.121
negative regulation of immune system process GO:0002683 136 0.120
response to abiotic stimulus GO:0009628 336 0.115
stem cell differentiation GO:0048863 93 0.112
Human
regulation of mapk cascade GO:0043408 262 0.112
Human Rat
positive regulation of transport GO:0051050 336 0.111
response to cytokine GO:0034097 232 0.110
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.108
sulfur compound metabolic process GO:0006790 101 0.105
segmentation GO:0035282 4 0.104
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.102
immune response GO:0006955 307 0.102
regulation of canonical wnt signaling pathway GO:0060828 88 0.102
dermatome development GO:0061054 3 0.101
extracellular structure organization GO:0043062 41 0.099
ossification GO:0001503 121 0.098
Human
positive regulation of immune system process GO:0002684 283 0.098
soft palate development GO:0060023 3 0.098
cell adhesion GO:0007155 325 0.095
Human
negative regulation of cell death GO:0060548 345 0.095
regulation of cytokine production GO:0001817 232 0.093
Human
positive regulation of apoptotic process GO:0043065 246 0.093
nervous system development GO:0007399 293 0.091
negative regulation of cellular component movement GO:0051271 106 0.089
cell substrate adhesion GO:0031589 132 0.087
Human
response to hormone GO:0009725 175 0.086
Rat
mapk cascade GO:0000165 288 0.085
Human Rat
cellular response to oxygen containing compound GO:1901701 276 0.083
regulation of odontogenesis GO:0042481 4 0.081
endodermal cell differentiation GO:0035987 31 0.081
prostate gland morphogenesis GO:0060512 1 0.080
cell matrix adhesion GO:0007160 85 0.080
signal transduction by phosphorylation GO:0023014 297 0.080
Human Rat
regulation of response to external stimulus GO:0032101 222 0.079
peptidyl tyrosine modification GO:0018212 170 0.076
cytokine production GO:0001816 247 0.076
Human
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.076
wnt signaling pathway GO:0016055 156 0.074
negative regulation of transport GO:0051051 176 0.074
digestive tract development GO:0048565 75 0.073
Human
tissue migration GO:0090130 119 0.073
negative regulation of gastrulation GO:2000542 4 0.072
Human
epithelium development GO:0060429 227 0.070
ras protein signal transduction GO:0007265 73 0.069
positive regulation of programmed cell death GO:0043068 249 0.068
regulation of kinase activity GO:0043549 314 0.066
Human
negative regulation of blood vessel morphogenesis GO:2000181 41 0.066
regulation of vasculature development GO:1901342 97 0.066
defense response GO:0006952 315 0.066
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.065
regulation of proteolysis GO:0030162 293 0.064
positive regulation of mapk cascade GO:0043410 190 0.063
Human
positive regulation of transferase activity GO:0051347 227 0.063
Human
positive regulation of cell differentiation GO:0045597 211 0.062
negative regulation of axon guidance GO:1902668 1 0.062
negative regulation of apoptotic process GO:0043066 316 0.062
biomineral tissue development GO:0031214 39 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.061
response to steroid hormone GO:0048545 80 0.061
Rat
cell development GO:0048468 328 0.061
Human
response to lipid GO:0033993 206 0.061
Rat
cell morphogenesis involved in differentiation GO:0000904 144 0.060
Human
detection of mechanical stimulus GO:0050982 4 0.060
apoptotic signaling pathway GO:0097190 268 0.060
regulation of protein processing GO:0070613 150 0.059
regulation of cell growth GO:0001558 135 0.057
Human
positive regulation of epithelial cell proliferation GO:0050679 65 0.057
Human
digestive system development GO:0055123 75 0.055
Human
blood circulation GO:0008015 113 0.055
regulation of cell morphogenesis GO:0022604 153 0.055
negative regulation of protein metabolic process GO:0051248 391 0.054
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.054
Human
cell chemotaxis GO:0060326 112 0.053
urogenital system development GO:0001655 65 0.053
negative regulation of embryonic development GO:0045992 4 0.053
Human
negative regulation of cell adhesion GO:0007162 64 0.053
Human
regulation of wnt signaling pathway GO:0030111 123 0.053
granulocyte migration GO:0097530 40 0.052
positive regulation of protein kinase activity GO:0045860 190 0.051
Human
negative regulation of cell differentiation GO:0045596 171 0.051
Human
bmp signaling pathway GO:0030509 49 0.051
regulation of leukocyte migration GO:0002685 63 0.050
system process GO:0003008 349 0.050
tube morphogenesis GO:0035239 95 0.050
Human
circulatory system process GO:0003013 113 0.050
negative regulation of neutrophil chemotaxis GO:0090024 2 0.049
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.049
cartilage development GO:0051216 31 0.049
negative regulation of vasculature development GO:1901343 43 0.049
regulation of cellular response to stress GO:0080135 244 0.049
Human Rat
biological adhesion GO:0022610 331 0.049
Human
positive regulation of organelle organization GO:0010638 195 0.048
small gtpase mediated signal transduction GO:0007264 78 0.048
negative regulation of nitric oxide mediated signal transduction GO:0010751 2 0.047
taxis GO:0042330 157 0.047
morphogenesis of an epithelium GO:0002009 60 0.046
regulation of cell cycle GO:0051726 393 0.046
regulation of protein serine threonine kinase activity GO:0071900 179 0.046
Human
regulation of apoptotic signaling pathway GO:2001233 175 0.046
negative regulation of transmembrane transport GO:0034763 29 0.046
multicellular organismal metabolic process GO:0044236 34 0.046
leukocyte migration GO:0050900 107 0.046
positive regulation of chemotaxis GO:0050921 57 0.045
positive regulation of phosphorylation GO:0042327 394 0.045
Human
mesenchyme development GO:0060485 59 0.045
negative regulation of cellular component organization GO:0051129 235 0.045
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.044
Human
negative regulation of peptidase activity GO:0010466 91 0.044
chemotaxis GO:0006935 157 0.044
luteolysis GO:0001554 3 0.044
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.044
Human Rat
regulation of dermatome development GO:0061183 3 0.044
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.043
secretion by cell GO:0032940 226 0.043
positive regulation of epithelial cell migration GO:0010634 55 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
female gamete generation GO:0007292 2 0.043
regulation of leukocyte chemotaxis GO:0002688 46 0.042
negative regulation of protein processing GO:0010955 142 0.042
membrane organization GO:0061024 292 0.042
regulation of immune response GO:0050776 201 0.042
motor neuron axon guidance GO:0008045 2 0.042
positive regulation of angiogenesis GO:0045766 51 0.042
single organism cell adhesion GO:0098602 179 0.042
regulation of ion transport GO:0043269 189 0.041
cellular response to nitrogen compound GO:1901699 144 0.041
cellular response to organic cyclic compound GO:0071407 127 0.041
protein localization to organelle GO:0033365 280 0.040
Human
negative regulation of programmed cell death GO:0043069 321 0.040
spinal cord development GO:0021510 4 0.039
negative regulation of catalytic activity GO:0043086 335 0.039
Human
negative regulation of protein maturation GO:1903318 142 0.038
regulation of response to wounding GO:1903034 101 0.038
regeneration GO:0031099 4 0.038
lipid metabolic process GO:0006629 381 0.038
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.038
regulation of establishment of protein localization GO:0070201 242 0.037
Human
erk1 and erk2 cascade GO:0070371 104 0.037
negative regulation of glomerulus development GO:0090194 2 0.037
embryonic morphogenesis GO:0048598 85 0.037
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.036
positive regulation of cellular component biogenesis GO:0044089 158 0.036
regulation of keratinocyte migration GO:0051547 4 0.036
skin development GO:0043588 76 0.036
forelimb morphogenesis GO:0035136 4 0.036
positive regulation of cytokine production GO:0001819 167 0.036
Human
response to organonitrogen compound GO:0010243 156 0.036
Rat
response to organic cyclic compound GO:0014070 204 0.036
Rat
embryo development GO:0009790 123 0.036
Human
regulation of cellular response to growth factor stimulus GO:0090287 76 0.035
negative regulation of intracellular signal transduction GO:1902532 183 0.035
Rat
regulation of cell substrate adhesion GO:0010810 68 0.034
Human
response to radiation GO:0009314 151 0.034
negative regulation of apoptotic signaling pathway GO:2001234 97 0.034
innate immune response GO:0045087 178 0.034
osteoblast differentiation GO:0001649 92 0.034
Human
corticospinal tract morphogenesis GO:0021957 1 0.034
ameboidal type cell migration GO:0001667 135 0.034
epithelial to mesenchymal transition GO:0001837 48 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.034
Human
regulation of growth GO:0040008 165 0.034
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
Human
cyclic nucleotide metabolic process GO:0009187 82 0.034
Human
negative regulation of cell growth GO:0030308 83 0.034
Human
digestive tract morphogenesis GO:0048546 56 0.034
Human
mesenchymal cell development GO:0014031 50 0.034
endomembrane system organization GO:0010256 196 0.034
cellular response to organonitrogen compound GO:0071417 124 0.033
epithelium migration GO:0090132 119 0.033
epithelial cell migration GO:0010631 119 0.033
negative regulation of non canonical wnt signaling pathway GO:2000051 1 0.033
multicellular organismal macromolecule metabolic process GO:0044259 29 0.033
positive regulation of ossification GO:0045778 32 0.033
stem cell development GO:0048864 69 0.033
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.033
chondrocyte development GO:0002063 1 0.033
metal ion transport GO:0030001 272 0.032
organ formation GO:0048645 3 0.032
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.032
cell type specific apoptotic process GO:0097285 125 0.032
activation of protein kinase activity GO:0032147 90 0.032
negative regulation of hydrolase activity GO:0051346 182 0.032
Human
embryonic forelimb morphogenesis GO:0035115 4 0.032
positive regulation of kinase activity GO:0033674 204 0.032
Human
negative regulation of response to external stimulus GO:0032102 83 0.031
cartilage condensation GO:0001502 1 0.031
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.031
proteoglycan metabolic process GO:0006029 29 0.030
plasma membrane organization GO:0007009 115 0.030
morphogenesis of a polarized epithelium GO:0001738 3 0.030
negative regulation of proteolysis GO:0045861 132 0.030
actin filament based process GO:0030029 224 0.030
Human
cell morphogenesis GO:0000902 296 0.030
Human
single organism membrane organization GO:0044802 268 0.030
regulation of cell development GO:0060284 161 0.030
cellular response to dna damage stimulus GO:0006974 379 0.029
extrinsic apoptotic signaling pathway GO:0097191 119 0.029
negative regulation of angiogenesis GO:0016525 39 0.029
multicellular organismal aging GO:0010259 3 0.029
negative regulation of cell proliferation GO:0008285 228 0.029
protein processing GO:0016485 226 0.029
morphogenesis of embryonic epithelium GO:0016331 4 0.029
regulation of endothelial cell proliferation GO:0001936 56 0.029
regulation of transmembrane transport GO:0034762 139 0.029
regulation of protein maturation GO:1903317 150 0.028
regulation of hormone levels GO:0010817 125 0.028
regulation of cellular component biogenesis GO:0044087 281 0.028
rho protein signal transduction GO:0007266 26 0.028
reproductive process GO:0022414 106 0.028
Rat
sequestering of metal ion GO:0051238 24 0.028
regulation of actin filament based process GO:0032970 141 0.028
Human
organ morphogenesis GO:0009887 147 0.028
Rat
positive regulation of leukocyte chemotaxis GO:0002690 38 0.028
leukocyte chemotaxis GO:0030595 76 0.027
response to nitrogen compound GO:1901698 184 0.027
Rat
positive regulation of protein transport GO:0051222 135 0.027
endoderm development GO:0007492 33 0.027
response to biotic stimulus GO:0009607 276 0.027
Human
positive regulation of stem cell differentiation GO:2000738 29 0.027
transmembrane transport GO:0055085 399 0.027
regulation of granulocyte chemotaxis GO:0071622 16 0.026
cellular response to lipid GO:0071396 127 0.026
negative regulation of granulocyte chemotaxis GO:0071623 2 0.026
post embryonic development GO:0009791 2 0.026
epithelial cell proliferation GO:0050673 128 0.026
Human
regulation of jnk cascade GO:0046328 73 0.026
Human Rat
response to inorganic substance GO:0010035 127 0.026
positive regulation of aldosterone metabolic process GO:0032346 2 0.026
regulation of protein transport GO:0051223 213 0.026
Human
reactive oxygen species metabolic process GO:0072593 75 0.026
tissue regeneration GO:0042246 3 0.026
positive regulation of hydrolase activity GO:0051345 331 0.026
Human
ion transmembrane transport GO:0034220 338 0.025
oogenesis GO:0048477 2 0.025
regulation of protein localization GO:0032880 296 0.025
Human
collagen metabolic process GO:0032963 28 0.025
positive regulation of catabolic process GO:0009896 310 0.025
Human
ribonucleoside catabolic process GO:0042454 406 0.025
Human
blood coagulation GO:0007596 76 0.025
protein oligomerization GO:0051259 173 0.025
negative regulation of endopeptidase activity GO:0010951 84 0.025
response to other organism GO:0051707 261 0.025
Human
regulation of peptidase activity GO:0052547 180 0.025
dendritic cell antigen processing and presentation GO:0002468 1 0.025
cell activation GO:0001775 213 0.025
inner ear morphogenesis GO:0042472 4 0.025
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.025
Human
locomotory behavior GO:0007626 1 0.025
menstrual cycle phase GO:0022601 2 0.024
regulation of reactive oxygen species metabolic process GO:2000377 41 0.024
positive regulation of odontogenesis GO:0042482 3 0.024
protein maturation GO:0051604 233 0.024
negative regulation of cell cycle GO:0045786 193 0.024
cellular metal ion homeostasis GO:0006875 146 0.024
prostate gland development GO:0030850 3 0.024
blastoderm segmentation GO:0007350 2 0.024
Human
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.024
growth GO:0040007 202 0.024
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.024
lung alveolus development GO:0048286 4 0.024
regulation of cysteine type endopeptidase activity GO:2000116 127 0.024
endothelial cell proliferation GO:0001935 65 0.024
myeloid leukocyte migration GO:0097529 62 0.023
embryonic hindlimb morphogenesis GO:0035116 2 0.023
response to fibroblast growth factor GO:0071774 39 0.023
hemopoiesis GO:0030097 180 0.023
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.023
negative regulation of endodermal cell differentiation GO:1903225 2 0.023
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
Human
bone mineralization GO:0030282 34 0.023
regulation of erk1 and erk2 cascade GO:0070372 99 0.023
organophosphate catabolic process GO:0046434 430 0.023
Human
nerve development GO:0021675 4 0.023
regulation of secretion by cell GO:1903530 177 0.023
negative regulation of cell substrate adhesion GO:0010812 24 0.023
Human
endoderm formation GO:0001706 33 0.023
positive regulation of osteoblast differentiation GO:0045669 23 0.023
regulation of intracellular transport GO:0032386 195 0.022
Human
cell projection organization GO:0030030 252 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
receptor metabolic process GO:0043112 81 0.022
bone trabecula formation GO:0060346 1 0.022
hindbrain development GO:0030902 3 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
Human
vesicle mediated transport GO:0016192 371 0.022
cytoplasmic transport GO:0016482 379 0.022
Human
regulation of endopeptidase activity GO:0052548 170 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.022
cellular homeostasis GO:0019725 196 0.022
regulation of endothelial cell migration GO:0010594 67 0.021
cellular response to cytokine stimulus GO:0071345 181 0.021
intracellular protein transport GO:0006886 270 0.021
Human
sprouting angiogenesis GO:0002040 29 0.021
single organism cellular localization GO:1902580 332 0.021
Human
regulation of tumor necrosis factor production GO:0032680 43 0.021
positive regulation of apoptotic signaling pathway GO:2001235 70 0.021
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 1 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
neural tube closure GO:0001843 3 0.021
negative regulation of epithelial cell proliferation GO:0050680 48 0.021
cell growth GO:0016049 160 0.021
Human
positive regulation of cellular catabolic process GO:0031331 284 0.021
Human
protein modification by small protein conjugation GO:0032446 342 0.021
nucleoside catabolic process GO:0009164 408 0.021
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
Human
positive regulation of endothelial cell proliferation GO:0001938 37 0.020
regulation of cell cycle process GO:0010564 266 0.020
blood vessel endothelial cell migration GO:0043534 42 0.020
generation of neurons GO:0048699 152 0.020
metencephalon development GO:0022037 2 0.020
response to mechanical stimulus GO:0009612 51 0.020
regulation of bmp signaling pathway GO:0030510 27 0.020
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
Human Rat
response to calcium ion GO:0051592 46 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
positive regulation of wnt signaling pathway GO:0030177 54 0.020
negative regulation of axonogenesis GO:0050771 4 0.020
retinal ganglion cell axon guidance GO:0031290 2 0.019
multicellular organismal response to stress GO:0033555 1 0.019
determination of adult lifespan GO:0008340 2 0.019
epithelial cell differentiation GO:0030855 141 0.019
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.019
Human Rat
endothelial cell migration GO:0043542 86 0.019
muscle system process GO:0003012 81 0.019
regulation of epithelial cell migration GO:0010632 93 0.019
regulation of receptor mediated endocytosis GO:0048259 32 0.019
negative regulation of immune response GO:0050777 40 0.019
inflammatory response GO:0006954 79 0.019
negative regulation of ion transport GO:0043271 39 0.019
protein catabolic process GO:0030163 325 0.019
hindlimb morphogenesis GO:0035137 2 0.019
anion transport GO:0006820 161 0.019
cell aggregation GO:0098743 1 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
Human
regulation of map kinase activity GO:0043405 108 0.019
Human
elastic fiber assembly GO:0048251 3 0.019
metal ion homeostasis GO:0055065 169 0.019
lipid biosynthetic process GO:0008610 177 0.019
peptide cross linking GO:0018149 12 0.019
positive regulation of cell adhesion GO:0045785 84 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
Human
axis elongation GO:0003401 4 0.018
amide transport GO:0042886 76 0.018
regulation of tooth mineralization GO:0070170 3 0.018
regulation of cell projection organization GO:0031344 107 0.018
regulation of protein kinase b signaling GO:0051896 61 0.018
positive regulation of immune response GO:0050778 159 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
convergent extension GO:0060026 1 0.018
skeletal system morphogenesis GO:0048705 24 0.018
cellular lipid metabolic process GO:0044255 303 0.018
protein ubiquitination GO:0016567 314 0.018
cell migration involved in gastrulation GO:0042074 1 0.018
regulation of cell activation GO:0050865 125 0.018
regulation of homeostatic process GO:0032844 121 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
nitrogen compound transport GO:0071705 191 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
Human
regulation of heart growth GO:0060420 4 0.018
cellular response to acid chemical GO:0071229 44 0.018
regulation of behavior GO:0050795 82 0.018
behavior GO:0007610 112 0.018
bone development GO:0060348 26 0.018
cellular protein catabolic process GO:0044257 261 0.018
glycoprotein metabolic process GO:0009100 110 0.018
negative regulation of protein modification process GO:0031400 200 0.018
stress activated protein kinase signaling cascade GO:0031098 94 0.018
Human Rat
ion homeostasis GO:0050801 230 0.018
formation of primary germ layer GO:0001704 42 0.018
Human
intracellular receptor signaling pathway GO:0030522 104 0.017
mesonephros development GO:0001823 17 0.017
somitogenesis GO:0001756 2 0.017
detection of mechanical stimulus involved in sensory perception GO:0050974 1 0.017
detection of stimulus involved in sensory perception GO:0050906 43 0.017
negative regulation of organelle organization GO:0010639 126 0.017
hematopoietic stem cell differentiation GO:0060218 4 0.017
detection of stimulus GO:0051606 85 0.017
secretion GO:0046903 254 0.017
response to acid chemical GO:0001101 66 0.017
actin filament organization GO:0007015 128 0.017
cellular divalent inorganic cation homeostasis GO:0072503 128 0.017
neural tube formation GO:0001841 3 0.017
negative regulation of growth GO:0045926 97 0.017
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.017
Human
regulation of ras protein signal transduction GO:0046578 155 0.017
Human
mesenchymal stem cell differentiation GO:0072497 8 0.017
Human
regulation of stress activated mapk cascade GO:0032872 84 0.017
Human Rat
negative regulation of cellular extravasation GO:0002692 5 0.017
syncytium formation by plasma membrane fusion GO:0000768 2 0.017
protein secretion GO:0009306 98 0.017
regulation of gastrulation GO:0010470 12 0.017
Human
primary neural tube formation GO:0014020 3 0.017
regulation of epithelial to mesenchymal transition GO:0010717 37 0.017
cell projection morphogenesis GO:0048858 129 0.017
mitotic cell cycle process GO:1903047 286 0.016
gastrulation GO:0007369 51 0.016
Human
reproductive system development GO:0061458 56 0.016
Rat
glycosyl compound catabolic process GO:1901658 413 0.016
Human
purine containing compound catabolic process GO:0072523 411 0.016
Human
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
jnk cascade GO:0007254 80 0.016
Human Rat
stress activated mapk cascade GO:0051403 93 0.016
Human Rat
signal release GO:0023061 70 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
sex determination GO:0007530 3 0.016
immune system development GO:0002520 195 0.016
maintenance of location GO:0051235 112 0.016
positive regulation of hormone biosynthetic process GO:0046886 4 0.016
activation of mapk activity GO:0000187 45 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
Human
negative regulation of phosphorylation GO:0042326 174 0.016
Rat
cellular macromolecular complex assembly GO:0034622 324 0.016
hormone secretion GO:0046879 65 0.016
peptide transport GO:0015833 74 0.016
limb development GO:0060173 23 0.016

SFRP4 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.355
connective tissue disease DOID:65 109 0.047
sensory system disease DOID:0050155 203 0.046
Human
nervous system disease DOID:863 431 0.046
Human
bone disease DOID:0080001 88 0.040
osteochondrodysplasia DOID:2256 35 0.034
bone development disease DOID:0080006 55 0.034
disease of cellular proliferation DOID:14566 174 0.028
cancer DOID:162 167 0.028
eye disease DOID:5614 149 0.025
Human
eye and adnexa disease DOID:1492 150 0.025
Human
retinal disease DOID:5679 118 0.019
Human
central nervous system disease DOID:331 186 0.018
retinal degeneration DOID:8466 89 0.016