Homo sapiens

0 known processes

SH2B1

SH2B adaptor protein 1

(Aliases: DKFZp547G1110,FLJ30542,SH2B,KIAA1299,PSM)

SH2B1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to interleukin 15 GO:0070672 6 0.530
neuron projection regeneration GO:0031102 1 0.510
enzyme linked receptor protein signaling pathway GO:0007167 303 0.402
Fly
cellular response to oxygen containing compound GO:1901701 276 0.391
Fly
response to hormone GO:0009725 175 0.351
Fly
chemical homeostasis GO:0048878 306 0.349
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.327
Fly
cellular lipid metabolic process GO:0044255 303 0.326
regulation of insulin receptor signaling pathway GO:0046626 13 0.321
Fly
cellular response to nitrogen compound GO:1901699 144 0.315
Fly
nitrogen compound transport GO:0071705 191 0.265
peptide secretion GO:0002790 51 0.252
lipid localization GO:0010876 106 0.245
cellular response to endogenous stimulus GO:0071495 336 0.245
Fly
ion transmembrane transport GO:0034220 338 0.242
regulation of transferase activity GO:0051338 355 0.240
cellular ketone metabolic process GO:0042180 80 0.232
regulation of cellular ketone metabolic process GO:0010565 50 0.232
cellular response to peptide hormone stimulus GO:0071375 56 0.231
Fly
cellular response to insulin stimulus GO:0032869 41 0.216
Fly
response to peptide hormone GO:0043434 61 0.210
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.210
asymmetric stem cell division GO:0098722 1 0.204
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.201
regulation of glycogen metabolic process GO:0070873 15 0.196
monocarboxylic acid metabolic process GO:0032787 185 0.191
regulation of glycogen biosynthetic process GO:0005979 14 0.190
response to oxygen containing compound GO:1901700 369 0.188
Fly
cellular amino acid metabolic process GO:0006520 116 0.187
response to peptide GO:1901652 65 0.185
Fly
cellular response to peptide GO:1901653 59 0.182
Fly
transmembrane transport GO:0055085 399 0.172
single organism carbohydrate metabolic process GO:0044723 193 0.171
female gamete generation GO:0007292 2 0.170
peptide transport GO:0015833 74 0.161
response to organonitrogen compound GO:0010243 156 0.159
Fly
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.154
regeneration GO:0031099 4 0.152
regulation of cellular response to insulin stimulus GO:1900076 17 0.150
Fly
regulation of protein serine threonine kinase activity GO:0071900 179 0.145
positive regulation of developmental process GO:0051094 314 0.144
fatty acid metabolic process GO:0006631 115 0.142
regulation of hormone secretion GO:0046883 57 0.142
regulation of glucose import GO:0046324 21 0.142
g protein coupled receptor signaling pathway GO:0007186 207 0.141
cellular response to organonitrogen compound GO:0071417 124 0.140
Fly
cellular amine metabolic process GO:0044106 41 0.140
negative regulation of developmental process GO:0051093 247 0.140
lipid metabolic process GO:0006629 381 0.137
regulation of glucose metabolic process GO:0010906 28 0.136
cell cell signaling GO:0007267 155 0.132
carbohydrate transport GO:0008643 37 0.131
regulation of carbohydrate metabolic process GO:0006109 54 0.131
monosaccharide metabolic process GO:0005996 74 0.126
negative regulation of cell proliferation GO:0008285 228 0.124
hormone mediated signaling pathway GO:0009755 22 0.123
negative regulation of cardiac muscle cell apoptotic process GO:0010667 2 0.119
negative regulation of phosphorylation GO:0042326 174 0.118
regulation of carbohydrate biosynthetic process GO:0043255 27 0.114
positive regulation of locomotion GO:0040017 186 0.114
amine metabolic process GO:0009308 44 0.114
hexose metabolic process GO:0019318 55 0.114
cellular response to hormone stimulus GO:0032870 125 0.113
Fly
positive regulation of glucose import in response to insulin stimulus GO:2001275 3 0.113
associative learning GO:0008306 1 0.112
negative regulation of glycogen metabolic process GO:0070874 4 0.111
small molecule catabolic process GO:0044282 92 0.111
positive regulation of kinase activity GO:0033674 204 0.110
axon regeneration GO:0031103 1 0.110
phospholipid metabolic process GO:0006644 99 0.109
negative regulation of cell death GO:0060548 345 0.109
positive regulation of hydrolase activity GO:0051345 331 0.108
negative regulation of protein phosphorylation GO:0001933 140 0.108
negative regulation of cell differentiation GO:0045596 171 0.106
regulation of activin receptor signaling pathway GO:0032925 14 0.104
negative regulation of cellular amine metabolic process GO:0033239 3 0.104
positive regulation of protein kinase activity GO:0045860 190 0.104
hexose transport GO:0008645 30 0.102
positive regulation of cellular catabolic process GO:0031331 284 0.101
cellular polysaccharide biosynthetic process GO:0033692 21 0.101
positive regulation of cell proliferation GO:0008284 301 0.100
regulation of peptide secretion GO:0002791 42 0.100
regulation of secretion by cell GO:1903530 177 0.095
purine ribonucleoside metabolic process GO:0046128 437 0.094
response to decreased oxygen levels GO:0036293 96 0.094
negative regulation of programmed cell death GO:0043069 321 0.093
response to cytokine GO:0034097 232 0.092
response to nitrogen compound GO:1901698 184 0.092
Fly
response to axon injury GO:0048678 1 0.091
insulin secretion GO:0030073 39 0.091
regulation of polysaccharide metabolic process GO:0032881 21 0.090
positive regulation of cellular component movement GO:0051272 181 0.090
regulation of polysaccharide biosynthetic process GO:0032885 20 0.089
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.089
glycogen biosynthetic process GO:0005978 16 0.088
interleukin 2 mediated signaling pathway GO:0038110 3 0.088
regulation of cellular component movement GO:0051270 334 0.087
negative regulation of phosphorus metabolic process GO:0010563 267 0.086
insulin receptor signaling pathway GO:0008286 23 0.086
Fly
segmentation GO:0035282 4 0.084
regulation of locomotion GO:0040012 329 0.084
regulation of kinase activity GO:0043549 314 0.083
regulation of protein kinase activity GO:0045859 289 0.083
regulation of cell cycle GO:0051726 393 0.082
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.082
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.081
negative regulation of protein metabolic process GO:0051248 391 0.081
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.080
glucose metabolic process GO:0006006 45 0.079
cellular carbohydrate biosynthetic process GO:0034637 21 0.079
positive regulation of protein phosphorylation GO:0001934 313 0.079
circulatory system process GO:0003013 113 0.078
organic anion transport GO:0015711 103 0.078
regulation of ion transmembrane transport GO:0034765 132 0.077
positive regulation of catabolic process GO:0009896 310 0.076
glycosyl compound catabolic process GO:1901658 413 0.075
polysaccharide biosynthetic process GO:0000271 27 0.074
glucan biosynthetic process GO:0009250 16 0.074
response to interleukin 13 GO:0035962 4 0.073
circadian behavior GO:0048512 2 0.073
blood circulation GO:0008015 113 0.072
signal release GO:0023061 70 0.071
memory GO:0007613 3 0.071
chromatin organization GO:0006325 351 0.070
post embryonic development GO:0009791 2 0.070
cell projection organization GO:0030030 252 0.070
Mouse
response to growth factor GO:0070848 205 0.070
negative regulation of catalytic activity GO:0043086 335 0.069
ribonucleoside triphosphate catabolic process GO:0009203 391 0.069
system process GO:0003008 349 0.068
negative regulation of wnt signaling pathway GO:0030178 69 0.068
positive regulation of glycogen biosynthetic process GO:0045725 10 0.067
positive regulation of cell migration GO:0030335 172 0.067
cellular ion homeostasis GO:0006873 168 0.066
determination of adult lifespan GO:0008340 2 0.066
cellular homeostasis GO:0019725 196 0.065
regulation of wnt signaling pathway GO:0030111 123 0.065
positive regulation of defense response GO:0031349 87 0.065
carbohydrate metabolic process GO:0005975 207 0.065
regulation of peptide hormone secretion GO:0090276 41 0.064
regulation of cellular amine metabolic process GO:0033238 11 0.064
activation of janus kinase activity GO:0042976 7 0.064
phosphatidylinositol mediated signaling GO:0048015 55 0.064
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.064
positive regulation of immune system process GO:0002684 283 0.062
oogenesis GO:0048477 2 0.062
amide transport GO:0042886 76 0.062
ribonucleoside triphosphate metabolic process GO:0009199 412 0.061
negative regulation of phosphate metabolic process GO:0045936 267 0.060
positive regulation of cell motility GO:2000147 177 0.060
monosaccharide transport GO:0015749 32 0.059
growth GO:0040007 202 0.059
Fly
anion transport GO:0006820 161 0.059
negative regulation of transport GO:0051051 176 0.059
response to abiotic stimulus GO:0009628 336 0.059
activation of protein kinase activity GO:0032147 90 0.058
cellular response to ph GO:0071467 9 0.058
covalent chromatin modification GO:0016569 254 0.058
negative regulation of tyrosine phosphorylation of stat3 protein GO:0042518 2 0.057
regulation of glucan biosynthetic process GO:0010962 14 0.057
positive regulation of cell division GO:0051781 59 0.057
Mouse
generation of precursor metabolites and energy GO:0006091 68 0.057
negative regulation of ion transmembrane transport GO:0034766 26 0.056
positive regulation of transport GO:0051050 336 0.056
mammary gland development GO:0030879 17 0.055
positive regulation of secretion by cell GO:1903532 108 0.054
regulation of cell migration GO:0030334 289 0.054
cellular response to interferon gamma GO:0071346 24 0.053
negative regulation of protein modification process GO:0031400 200 0.052
negative regulation of kinase activity GO:0033673 106 0.051
rab protein signal transduction GO:0032482 4 0.050
glucan metabolic process GO:0044042 22 0.050
positive regulation of programmed cell death GO:0043068 249 0.050
positive regulation of cellular component organization GO:0051130 376 0.049
Mouse
apoptotic signaling pathway GO:0097190 268 0.049
carboxylic acid catabolic process GO:0046395 71 0.049
glycogen metabolic process GO:0005977 22 0.049
regulation of mapk cascade GO:0043408 262 0.049
interleukin 12 mediated signaling pathway GO:0035722 3 0.049
negative regulation of insulin receptor signaling pathway GO:0046627 8 0.048
alcohol metabolic process GO:0006066 114 0.048
regulation of secretion GO:0051046 194 0.048
mitotic cell cycle GO:0000278 326 0.048
Mouse
positive regulation of apoptotic process GO:0043065 246 0.048
cell development GO:0048468 328 0.047
response to manganese ion GO:0010042 2 0.047
striated muscle cell apoptotic process GO:0010658 3 0.047
regulation of lipid metabolic process GO:0019216 96 0.047
regulation of map kinase activity GO:0043405 108 0.047
regulation of peptide transport GO:0090087 62 0.047
erythrocyte homeostasis GO:0034101 31 0.047
positive regulation of cell death GO:0010942 263 0.047
positive regulation of peptide hormone secretion GO:0090277 15 0.046
regulation of body fluid levels GO:0050878 99 0.046
reactive nitrogen species metabolic process GO:2001057 3 0.046
long term memory GO:0007616 2 0.045
glycoprotein metabolic process GO:0009100 110 0.045
negative regulation of multicellular organismal process GO:0051241 317 0.045
regulation of protein import into nucleus GO:0042306 78 0.045
response to biotic stimulus GO:0009607 276 0.045
positive regulation of phosphorylation GO:0042327 394 0.044
positive regulation of map kinase activity GO:0043406 80 0.044
response to insulin GO:0032868 45 0.044
Fly
signal transduction by phosphorylation GO:0023014 297 0.044
endothelial cell proliferation GO:0001935 65 0.044
negative regulation of transferase activity GO:0051348 124 0.044
ion homeostasis GO:0050801 230 0.043
response to organic cyclic compound GO:0014070 204 0.043
regulation of inflammatory response GO:0050727 46 0.043
regulation of protein localization GO:0032880 296 0.043
glycerolipid biosynthetic process GO:0045017 51 0.043
regulation of endopeptidase activity GO:0052548 170 0.043
metal ion homeostasis GO:0055065 169 0.043
stem cell division GO:0017145 2 0.042
inorganic anion transport GO:0015698 60 0.042
regulation of growth GO:0040008 165 0.042
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
activation of mapk activity GO:0000187 45 0.041
protein targeting GO:0006605 187 0.041
sex determination GO:0007530 3 0.041
positive regulation of hormone secretion GO:0046887 25 0.041
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.041
lipid modification GO:0030258 84 0.041
regulation of establishment of protein localization GO:0070201 242 0.041
locomotory behavior GO:0007626 1 0.041
secretion GO:0046903 254 0.040
protein maturation GO:0051604 233 0.040
regulation of intracellular protein transport GO:0033157 123 0.040
blastoderm segmentation GO:0007350 2 0.040
glucose transport GO:0015758 30 0.040
syncytium formation by plasma membrane fusion GO:0000768 2 0.040
peptide hormone secretion GO:0030072 50 0.040
head development GO:0060322 108 0.040
multicellular organismal aging GO:0010259 3 0.039
regulation of cell motility GO:2000145 299 0.039
carbohydrate biosynthetic process GO:0016051 42 0.039
negative regulation of protein kinase activity GO:0006469 98 0.039
cellular response to dexamethasone stimulus GO:0071549 1 0.039
epithelium development GO:0060429 227 0.038
lipid biosynthetic process GO:0008610 177 0.038
regulation of tumor necrosis factor production GO:0032680 43 0.038
mating GO:0007618 1 0.038
Fly
cellular glucan metabolic process GO:0006073 22 0.038
regulation of immune response GO:0050776 201 0.038
cellular response to lipid GO:0071396 127 0.038
vesicle mediated transport GO:0016192 371 0.037
positive regulation of lipid metabolic process GO:0045834 50 0.037
cellular response to tumor necrosis factor GO:0071356 63 0.036
organic acid catabolic process GO:0016054 71 0.036
monocarboxylic acid catabolic process GO:0072329 37 0.036
regulation of cytokine production GO:0001817 232 0.036
regulation of cellular component biogenesis GO:0044087 281 0.036
cell morphogenesis GO:0000902 296 0.036
hindbrain development GO:0030902 3 0.036
oxidation reduction process GO:0055114 396 0.036
negative regulation of secretion by cell GO:1903531 52 0.036
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
negative regulation of type i interferon mediated signaling pathway GO:0060339 4 0.035
regulation of cytoplasmic transport GO:1903649 149 0.035
interleukin 6 mediated signaling pathway GO:0070102 7 0.035
energy derivation by oxidation of organic compounds GO:0015980 43 0.035
protein autophosphorylation GO:0046777 123 0.035
nucleotide catabolic process GO:0009166 408 0.035
cellular response to cytokine stimulus GO:0071345 181 0.035
organic hydroxy compound metabolic process GO:1901615 147 0.035
cellular response to dna damage stimulus GO:0006974 379 0.035
cardiac muscle cell apoptotic process GO:0010659 3 0.035
positive regulation of proteolysis GO:0045862 142 0.035
regulation of intracellular transport GO:0032386 195 0.035
ameboidal type cell migration GO:0001667 135 0.035
positive regulation of rab gtpase activity GO:0032851 39 0.035
response to other organism GO:0051707 261 0.034
purine containing compound catabolic process GO:0072523 411 0.034
organophosphate biosynthetic process GO:0090407 163 0.034
cell growth GO:0016049 160 0.034
negative regulation of carbohydrate metabolic process GO:0045912 20 0.033
nervous system development GO:0007399 293 0.033
single organism cellular localization GO:1902580 332 0.032
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.032
regulation of striated muscle cell apoptotic process GO:0010662 3 0.032
ribonucleoside monophosphate catabolic process GO:0009158 158 0.032
cytokine mediated signaling pathway GO:0019221 109 0.032
positive regulation of nucleotide catabolic process GO:0030813 185 0.032
regulation of reactive oxygen species metabolic process GO:2000377 41 0.032
regulation of glucose transport GO:0010827 23 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.032
response to oxygen levels GO:0070482 100 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.031
tricarboxylic acid metabolic process GO:0072350 4 0.031
innate immune response GO:0045087 178 0.031
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.031
cellular chemical homeostasis GO:0055082 180 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.031
biological adhesion GO:0022610 331 0.031
cellular polysaccharide metabolic process GO:0044264 27 0.031
regulation of apoptotic signaling pathway GO:2001233 175 0.030
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.030
glucose import GO:0046323 24 0.030
regulation of system process GO:0044057 101 0.030
neurogenesis GO:0022008 169 0.030
lipid catabolic process GO:0016042 84 0.030
negative regulation of tyrosine phosphorylation of stat protein GO:0042532 2 0.030
regulation of glucose import in response to insulin stimulus GO:2001273 4 0.030
cellular component morphogenesis GO:0032989 314 0.030
ribonucleoside catabolic process GO:0042454 406 0.029
protein catabolic process GO:0030163 325 0.029
single organism membrane organization GO:0044802 268 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.029
histone modification GO:0016570 251 0.029
cellular response to growth factor stimulus GO:0071363 197 0.029
peripheral nervous system development GO:0007422 2 0.029
organophosphate catabolic process GO:0046434 430 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 2 0.028
positive regulation of cell activation GO:0050867 81 0.028
regulation of nucleocytoplasmic transport GO:0046822 98 0.028
regulation of endothelial cell proliferation GO:0001936 56 0.028
convergent extension GO:0060026 1 0.028
hormone transport GO:0009914 68 0.028
defense response GO:0006952 315 0.028
cell division GO:0051301 168 0.028
Mouse
regulation of interleukin 6 mediated signaling pathway GO:0070103 3 0.028
cellular response to interleukin 15 GO:0071350 6 0.028
cardiovascular system development GO:0072358 262 0.027
negative regulation of epithelial cell proliferation GO:0050680 48 0.027
nucleocytoplasmic transport GO:0006913 176 0.027
positive regulation of glucose metabolic process GO:0010907 12 0.027
response to tumor necrosis factor GO:0034612 76 0.027
purine nucleotide catabolic process GO:0006195 405 0.027
cytoplasmic transport GO:0016482 379 0.027
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.027
positive regulation of peptidase activity GO:0010952 88 0.027
positive regulation of intracellular protein transport GO:0090316 76 0.027
response to interleukin 12 GO:0070671 3 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
immune response GO:0006955 307 0.026
wnt signaling pathway GO:0016055 156 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
intrinsic apoptotic signaling pathway GO:0097193 127 0.026
actin filament based process GO:0030029 224 0.026
regulation of innate immune response GO:0045088 97 0.026
cellular response to biotic stimulus GO:0071216 71 0.026
intracellular protein transport GO:0006886 270 0.026
regulation of gamma delta t cell activation GO:0046643 1 0.025
positive regulation of immune response GO:0050778 159 0.025
negative regulation of heart contraction GO:0045822 3 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
negative regulation of secretion GO:0051048 58 0.025
epithelial cell differentiation GO:0030855 141 0.025
protein localization to nucleus GO:0034504 136 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.024
peptidyl tyrosine phosphorylation GO:0018108 170 0.024
ribonucleotide catabolic process GO:0009261 405 0.024
cation transmembrane transport GO:0098655 238 0.024
regulation of protein transport GO:0051223 213 0.024
natural killer cell differentiation GO:0001779 2 0.024
positive regulation of endopeptidase activity GO:0010950 84 0.024
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.024
morphogenesis of embryonic epithelium GO:0016331 4 0.024
positive regulation of organelle organization GO:0010638 195 0.024
Mouse
positive regulation of carbohydrate metabolic process GO:0045913 21 0.024
regulation of mitosis GO:0007088 63 0.024
Mouse
negative regulation of transmembrane transport GO:0034763 29 0.024
positive regulation of fatty acid metabolic process GO:0045923 11 0.024
cellular response to glucocorticoid stimulus GO:0071385 4 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
circadian sleep wake cycle process GO:0022410 2 0.024
negative regulation of glycogen biosynthetic process GO:0045719 3 0.024
positive regulation of fatty acid beta oxidation GO:0032000 5 0.024
peptidyl tyrosine modification GO:0018212 170 0.023
peptidyl lysine modification GO:0018205 144 0.023
inositol lipid mediated signaling GO:0048017 55 0.023
positive regulation of mapk cascade GO:0043410 190 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
regulation of protein localization to nucleus GO:1900180 85 0.023
dna replication GO:0006260 116 0.023
glucose import in response to insulin stimulus GO:0044381 4 0.023
neural tube formation GO:0001841 3 0.023
erythrocyte development GO:0048821 3 0.022
modification dependent macromolecule catabolic process GO:0043632 212 0.022
cation homeostasis GO:0055080 189 0.022
cell projection morphogenesis GO:0048858 129 0.022
actin filament based movement GO:0030048 17 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
positive regulation of insulin secretion GO:0032024 10 0.022
regulation of binding GO:0051098 111 0.022
sleep GO:0030431 2 0.022
stem cell differentiation GO:0048863 93 0.022
regulation of cell division GO:0051302 116 0.022
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.022
regulation of cell growth GO:0001558 135 0.022
behavior GO:0007610 112 0.022
Fly
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.022
negative regulation of cell adhesion GO:0007162 64 0.022
regulation of blood circulation GO:1903522 59 0.021
chromatin modification GO:0016568 298 0.021
membrane lipid metabolic process GO:0006643 53 0.021
interleukin 4 mediated signaling pathway GO:0035771 3 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
negative regulation of cellular response to insulin stimulus GO:1900077 8 0.021
actin mediated cell contraction GO:0070252 12 0.021
positive regulation of cell differentiation GO:0045597 211 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
somitogenesis GO:0001756 2 0.021
positive regulation of glycogen metabolic process GO:0070875 10 0.021
positive regulation of cytoplasmic transport GO:1903651 82 0.021
regulation of vasculature development GO:1901342 97 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
protein localization to organelle GO:0033365 280 0.021
polysaccharide metabolic process GO:0005976 33 0.021
rhythmic behavior GO:0007622 2 0.021
regulation of transporter activity GO:0032409 82 0.021
regulation of interleukin 1 production GO:0032652 21 0.020
positive regulation of secretion GO:0051047 116 0.020
cell morphogenesis involved in differentiation GO:0000904 144 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.020
response to nutrient levels GO:0031667 81 0.020
regulation of hydrogen peroxide metabolic process GO:0010310 6 0.020
positive regulation of lymphocyte activation GO:0051251 73 0.020
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
myeloid cell differentiation GO:0030099 117 0.020
regulation of nervous system development GO:0051960 88 0.020
secretion by cell GO:0032940 226 0.020
negative regulation of blood circulation GO:1903523 4 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
protein acetylation GO:0006473 116 0.020
protein oligomerization GO:0051259 173 0.020
glycoprotein biosynthetic process GO:0009101 91 0.020
glycerophospholipid biosynthetic process GO:0046474 40 0.020
lipid oxidation GO:0034440 33 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
cellular amide metabolic process GO:0043603 69 0.020
regulation of transmembrane transport GO:0034762 139 0.020
regulation of rab gtpase activity GO:0032313 39 0.019
heart process GO:0003015 62 0.019
regulation of hormone levels GO:0010817 125 0.019
regulation of epithelial cell proliferation GO:0050678 113 0.019
response to ph GO:0009268 12 0.019
negative regulation of erythrocyte differentiation GO:0045647 3 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
positive regulation of peptide secretion GO:0002793 15 0.019
organelle fission GO:0048285 149 0.019
Mouse
myoblast fusion GO:0007520 1 0.019
cellular response to external stimulus GO:0071496 111 0.019
response to lipid GO:0033993 206 0.019
anion transmembrane transport GO:0098656 76 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.019
regulation of natural killer cell differentiation GO:0032823 2 0.019
response to ionizing radiation GO:0010212 65 0.019
positive regulation of cellular response to insulin stimulus GO:1900078 6 0.019
Fly
regulation of cell cycle process GO:0010564 266 0.019
Mouse
zymogen activation GO:0031638 70 0.019
compound eye development GO:0048749 1 0.019
reproductive process GO:0022414 106 0.019
Fly
neuron differentiation GO:0030182 138 0.019
response to interferon gamma GO:0034341 39 0.019
regulation of cellular response to stress GO:0080135 244 0.019
mapk cascade GO:0000165 288 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
positive regulation of binding GO:0051099 45 0.018
positive regulation of response to wounding GO:1903036 28 0.018
regulation of glycoprotein metabolic process GO:1903018 19 0.018
cellular lipid catabolic process GO:0044242 65 0.018
maintenance of location GO:0051235 112 0.018
regulation of defense response GO:0031347 154 0.018
sphingolipid metabolic process GO:0006665 38 0.018
cellular metal ion homeostasis GO:0006875 146 0.018
regulation of fatty acid beta oxidation GO:0031998 8 0.018
positive regulation of apoptotic signaling pathway GO:2001235 70 0.018
defense response to virus GO:0051607 71 0.018
neurological system process GO:0050877 163 0.018
regulation of response to external stimulus GO:0032101 222 0.018
metencephalon development GO:0022037 2 0.018

SH2B1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.435
diabetes mellitus DOID:9351 31 0.276
carbohydrate metabolism disease DOID:0050013 32 0.276
glucose metabolism disease DOID:4194 32 0.276
acquired metabolic disease DOID:0060158 58 0.276
type 2 diabetes mellitus DOID:9352 28 0.242
inherited metabolic disorder DOID:655 242 0.082
carbohydrate metabolic disorder DOID:2978 55 0.056
immune system disease DOID:2914 155 0.040
hematopoietic system disease DOID:74 100 0.040
myeloma DOID:0070004 7 0.035
Human
immune system cancer DOID:0060083 36 0.035
Human
hematologic cancer DOID:2531 36 0.035
Human
cancer DOID:162 167 0.035
Human
disease of cellular proliferation DOID:14566 174 0.035
Human
organ system cancer DOID:0050686 164 0.035
Human
bone marrow cancer DOID:4960 10 0.035
Human
bone marrow disease DOID:4961 31 0.019