Homo sapiens

30 known processes

SH3KBP1

SH3-domain kinase binding protein 1

(Aliases: CD2BP3,CIN85,GIG10,HSB-1,HSB1,MIG18)

SH3KBP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament organization GO:0007015 128 1.000
Fly
purine nucleoside catabolic process GO:0006152 398 1.000
regulation of receptor mediated endocytosis GO:0048259 32 1.000
Fly
actin filament based process GO:0030029 224 0.999
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.999
glycosyl compound catabolic process GO:1901658 413 0.999
ribonucleotide catabolic process GO:0009261 405 0.999
nucleotide catabolic process GO:0009166 408 0.999
phosphatidylinositol mediated signaling GO:0048015 55 0.999
gtp catabolic process GO:0006184 237 0.999
positive regulation of mapk cascade GO:0043410 190 0.998
mapk cascade GO:0000165 288 0.998
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.998
negative regulation of transforming growth factor beta1 production GO:0032911 2 0.998
purine ribonucleotide catabolic process GO:0009154 404 0.998
guanosine containing compound metabolic process GO:1901068 244 0.998
regulation of cellular ketone metabolic process GO:0010565 50 0.998
actin cytoskeleton organization GO:0030036 207 0.997
Fly
positive regulation of protein kinase b signaling GO:0051897 42 0.997
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.997
positive regulation of phosphorylation GO:0042327 394 0.997
regulation of cellular amine metabolic process GO:0033238 11 0.997
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.997
ras protein signal transduction GO:0007265 73 0.997
signal transduction by phosphorylation GO:0023014 297 0.996
cellular ketone metabolic process GO:0042180 80 0.996
organophosphate catabolic process GO:0046434 430 0.995
negative regulation of apoptotic process GO:0043066 316 0.995
regulation of purine nucleotide metabolic process GO:1900542 264 0.995
purine ribonucleoside catabolic process GO:0046130 398 0.994
small gtpase mediated signal transduction GO:0007264 78 0.994
ribonucleoside triphosphate catabolic process GO:0009203 391 0.994
nucleoside catabolic process GO:0009164 408 0.993
regulation of kinase activity GO:0043549 314 0.992
ribonucleoside triphosphate metabolic process GO:0009199 412 0.991
immune system development GO:0002520 195 0.991
purine nucleotide catabolic process GO:0006195 405 0.991
positive regulation of transferase activity GO:0051347 227 0.990
rho protein signal transduction GO:0007266 26 0.990
nucleoside triphosphate catabolic process GO:0009143 394 0.990
ribonucleoside catabolic process GO:0042454 406 0.988
cellular amino acid metabolic process GO:0006520 116 0.988
purine nucleoside triphosphate metabolic process GO:0009144 412 0.987
amine metabolic process GO:0009308 44 0.986
guanosine containing compound catabolic process GO:1901069 239 0.985
nucleoside phosphate catabolic process GO:1901292 412 0.984
vesicle mediated transport GO:0016192 371 0.981
Fly
regulation of ras gtpase activity GO:0032318 128 0.980
lipid metabolic process GO:0006629 381 0.980
purine containing compound catabolic process GO:0072523 411 0.978
inositol lipid mediated signaling GO:0048017 55 0.978
protein localization to organelle GO:0033365 280 0.976
regulation of anatomical structure morphogenesis GO:0022603 286 0.976
endosomal transport GO:0016197 129 0.976
regulation of cytoskeleton organization GO:0051493 177 0.975
regulation of gtpase activity GO:0043087 180 0.975
purine ribonucleoside metabolic process GO:0046128 437 0.974
enzyme linked receptor protein signaling pathway GO:0007167 303 0.972
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.971
cellular amine metabolic process GO:0044106 41 0.971
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.971
endocytosis GO:0006897 159 0.970
Fly
positive regulation of rho gtpase activity GO:0032321 56 0.969
regulation of actin filament based process GO:0032970 141 0.969
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.966
regulation of cellular component biogenesis GO:0044087 281 0.966
regulation of protein serine threonine kinase activity GO:0071900 179 0.965
gtp metabolic process GO:0046039 239 0.965
regulation of cellular amino acid metabolic process GO:0006521 6 0.964
positive regulation of ras gtpase activity GO:0032320 117 0.964
arf protein signal transduction GO:0032011 0 0.964
positive regulation of nucleotide catabolic process GO:0030813 185 0.963
positive regulation of secretion by cell GO:1903532 108 0.960
engulfment of apoptotic cell GO:0043652 2 0.958
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.956
protein localization to nucleus GO:0034504 136 0.955
peptidyl serine phosphorylation GO:0018105 101 0.954
carbohydrate metabolic process GO:0005975 207 0.953
regulation of rho gtpase activity GO:0032319 66 0.953
positive regulation of jnk cascade GO:0046330 52 0.953
regulation of gtp catabolic process GO:0033124 180 0.952
regulation of purine nucleotide catabolic process GO:0033121 205 0.952
erk1 and erk2 cascade GO:0070371 104 0.951
nucleoside triphosphate metabolic process GO:0009141 422 0.947
regulation of map kinase activity GO:0043405 108 0.945
positive regulation of kinase activity GO:0033674 204 0.940
regulation of actin cytoskeleton organization GO:0032956 116 0.940
regulation of ras protein signal transduction GO:0046578 155 0.939
regulation of protein oligomerization GO:0032459 26 0.938
regulation of lymphocyte activation GO:0051249 103 0.935
protein oligomerization GO:0051259 173 0.926
protein kinase b signaling GO:0043491 69 0.920
organelle localization GO:0051640 84 0.919
cellular ion homeostasis GO:0006873 168 0.919
negative regulation of cell death GO:0060548 345 0.914
positive regulation of cellular amine metabolic process GO:0033240 7 0.908
regulation of epithelial cell migration GO:0010632 93 0.906
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.903
response to growth factor GO:0070848 205 0.902
cellular chemical homeostasis GO:0055082 180 0.902
regulation of protein localization to nucleus GO:1900180 85 0.896
negative regulation of map kinase activity GO:0043407 27 0.893
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.893
regulation of nucleoside metabolic process GO:0009118 209 0.891
adherens junction organization GO:0034332 36 0.891
positive regulation of transport GO:0051050 336 0.886
Fly
transforming growth factor beta1 production GO:0032905 3 0.885
synaptic vesicle endocytosis GO:0048488 2 0.883
regulation of protein kinase activity GO:0045859 289 0.881
cellular metal ion homeostasis GO:0006875 146 0.875
regulation of rho protein signal transduction GO:0035023 79 0.873
positive regulation of protein localization to nucleus GO:1900182 48 0.869
synaptic vesicle recycling GO:0036465 3 0.860
epithelial cell migration GO:0010631 119 0.857
Fly
phospholipid metabolic process GO:0006644 99 0.851
regulation of small gtpase mediated signal transduction GO:0051056 156 0.848
regulation of nucleotide catabolic process GO:0030811 205 0.847
positive regulation of cellular component organization GO:0051130 376 0.834
Fly
growth involved in symbiotic interaction GO:0044110 2 0.829
caveolin mediated endocytosis GO:0072584 4 0.828
positive regulation of secretion GO:0051047 116 0.828
activation of protein kinase activity GO:0032147 90 0.827
regulation of jnk cascade GO:0046328 73 0.826
regulation of protein complex assembly GO:0043254 147 0.812
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.812
regulation of protein kinase b signaling GO:0051896 61 0.809
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.808
regulation of exosomal secretion GO:1903541 12 0.804
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.792
ion homeostasis GO:0050801 230 0.789
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.785
positive regulation of cellular component biogenesis GO:0044089 158 0.782
macroautophagy GO:0016236 39 0.782
chromatin assembly or disassembly GO:0006333 78 0.779
receptor mediated endocytosis GO:0006898 84 0.772
Fly
negative regulation of protein phosphorylation GO:0001933 140 0.768
positive regulation of stress activated mapk cascade GO:0032874 60 0.766
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.762
jnk cascade GO:0007254 80 0.762
ameboidal type cell migration GO:0001667 135 0.753
Fly
membrane budding GO:0006900 28 0.752
cellular calcium ion homeostasis GO:0006874 117 0.749
early endosome to late endosome transport GO:0045022 21 0.737
positive regulation of gtpase activity GO:0043547 166 0.735
positive regulation of lymphocyte activation GO:0051251 73 0.730
glial cell migration GO:0008347 4 0.727
negative regulation of programmed cell death GO:0043069 321 0.704
regulation of cell differentiation GO:0045595 393 0.703
regulation of actin filament polymerization GO:0030833 50 0.701
activation of mapkk activity GO:0000186 18 0.699
negative regulation of mapk cascade GO:0043409 56 0.697
regulation of peptidyl serine phosphorylation GO:0033135 50 0.695
negative regulation of intracellular signal transduction GO:1902532 183 0.694
cytoplasmic transport GO:0016482 379 0.693
positive regulation of nucleoside metabolic process GO:0045979 186 0.692
cellular response to growth factor stimulus GO:0071363 197 0.687
positive regulation of immune system process GO:0002684 283 0.684
growth of symbiont in host GO:0044117 1 0.681
negative regulation of kinase activity GO:0033673 106 0.678
regulation of cytokine production GO:0001817 232 0.675
stress fiber assembly GO:0043149 40 0.667
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.661
regulation of stress activated mapk cascade GO:0032872 84 0.660
regulation of transforming growth factor beta1 production GO:0032908 3 0.641
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.637
positive regulation of leukocyte activation GO:0002696 80 0.635
establishment of organelle localization GO:0051656 59 0.630
actin filament bundle assembly GO:0051017 54 0.627
notch signaling pathway GO:0007219 31 0.625
negative regulation of peptidyl threonine phosphorylation GO:0010801 6 0.609
positive regulation of protein phosphorylation GO:0001934 313 0.607
positive regulation of cellular catabolic process GO:0031331 284 0.601
leukocyte differentiation GO:0002521 98 0.598
cell activation GO:0001775 213 0.596
cellular component morphogenesis GO:0032989 314 0.584
lung growth GO:0060437 2 0.584
single organism carbohydrate metabolic process GO:0044723 193 0.581
positive regulation of p38mapk cascade GO:1900745 8 0.580
salivary gland morphogenesis GO:0007435 4 0.578
cation homeostasis GO:0055080 189 0.576
peptidyl threonine modification GO:0018210 45 0.576
cellular macromolecular complex assembly GO:0034622 324 0.571
hemopoiesis GO:0030097 180 0.567
peptidyl threonine phosphorylation GO:0018107 41 0.563
growth GO:0040007 202 0.557
negative regulation of leukocyte apoptotic process GO:2000107 16 0.557
system process GO:0003008 349 0.554
endothelial cell migration GO:0043542 86 0.553
stress activated protein kinase signaling cascade GO:0031098 94 0.552
positive regulation of gtp catabolic process GO:0033126 166 0.551
defense response GO:0006952 315 0.550
cell division GO:0051301 168 0.549
Fly
vesicle organization GO:0016050 62 0.547
cell cell signaling GO:0007267 155 0.541
Fly
membrane organization GO:0061024 292 0.541
apoptotic cell clearance GO:0043277 12 0.538
cellular carbohydrate metabolic process GO:0044262 84 0.537
hindbrain development GO:0030902 3 0.536
positive regulation of hydrolase activity GO:0051345 331 0.532
positive regulation of rac gtpase activity GO:0032855 31 0.521
cellular cation homeostasis GO:0030003 163 0.517
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.505
cellular response to biotic stimulus GO:0071216 71 0.503
regulation of homeostatic process GO:0032844 121 0.502
positive regulation of exocytosis GO:0045921 35 0.497
regulation of transferase activity GO:0051338 355 0.488
organic hydroxy compound metabolic process GO:1901615 147 0.479
positive regulation of lipid metabolic process GO:0045834 50 0.466
cdc42 protein signal transduction GO:0032488 4 0.459
regulation of locomotion GO:0040012 329 0.454
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.452
negative regulation of protein modification process GO:0031400 200 0.448
positive regulation of cell motility GO:2000147 177 0.437
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.436
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.436
glycerophospholipid metabolic process GO:0006650 84 0.428
b cell activation GO:0042113 33 0.426
associative learning GO:0008306 1 0.426
actin filament polymerization GO:0030041 45 0.424
leukocyte activation GO:0045321 164 0.414
positive regulation of nucleotide metabolic process GO:0045981 230 0.408
negative regulation of protein oligomerization GO:0032460 8 0.405
response to fibroblast growth factor GO:0071774 39 0.402
establishment of vesicle localization GO:0051650 23 0.391
divalent inorganic cation homeostasis GO:0072507 136 0.386
t cell activation GO:0042110 99 0.386
negative regulation of apoptotic signaling pathway GO:2001234 97 0.384
single organism reproductive process GO:0044702 98 0.384
Fly
regulation of growth of symbiont in host GO:0044126 1 0.375
cytokine production GO:0001816 247 0.375
chemical homeostasis GO:0048878 306 0.373
branch elongation of an epithelium GO:0060602 3 0.370
positive regulation of cell proliferation GO:0008284 301 0.369
positive regulation of cell differentiation GO:0045597 211 0.368
positive regulation of leukocyte differentiation GO:1902107 37 0.363
positive regulation of catabolic process GO:0009896 310 0.358
regulation of lamellipodium morphogenesis GO:2000392 4 0.357
regulation of secretion GO:0051046 194 0.357
hematopoietic or lymphoid organ development GO:0048534 186 0.355
regulation of protein transport GO:0051223 213 0.351
intrinsic apoptotic signaling pathway GO:0097193 127 0.347
exocytosis GO:0006887 71 0.345
cell morphogenesis GO:0000902 296 0.345
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.345
negative regulation of catabolic process GO:0009895 104 0.345
negative regulation of catalytic activity GO:0043086 335 0.342
regulation of apoptotic signaling pathway GO:2001233 175 0.336
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.335
positive regulation of map kinase activity GO:0043406 80 0.334
multicellular organismal aging GO:0010259 3 0.334
regulation of anatomical structure size GO:0090066 101 0.329
protein targeting GO:0006605 187 0.329
cellular zinc ion homeostasis GO:0006882 10 0.329
syncytium formation by plasma membrane fusion GO:0000768 2 0.328
anatomical structure formation involved in morphogenesis GO:0048646 284 0.324
single organism cellular localization GO:1902580 332 0.323
cell projection assembly GO:0030031 126 0.320
cellular response to starvation GO:0009267 58 0.319
positive regulation of b cell differentiation GO:0045579 1 0.317
positive regulation of behavior GO:0048520 60 0.312
cellular lipid metabolic process GO:0044255 303 0.310
response to external biotic stimulus GO:0043207 261 0.303
sex determination GO:0007530 3 0.301
stress activated mapk cascade GO:0051403 93 0.293
regulation of endothelial cell apoptotic process GO:2000351 24 0.292
negative regulation of cellular amine metabolic process GO:0033239 3 0.291
positive regulation of actin filament polymerization GO:0030838 38 0.289
rac protein signal transduction GO:0016601 12 0.287
positive regulation of protein oligomerization GO:0032461 17 0.287
interspecies interaction between organisms GO:0044419 156 0.286
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.281
regulation of erk1 and erk2 cascade GO:0070372 99 0.278
response to biotic stimulus GO:0009607 276 0.277
regulation of transmembrane transport GO:0034762 139 0.277
negative regulation of protein metabolic process GO:0051248 391 0.276
membrane tubulation GO:0097320 12 0.270
positive regulation of cytoplasmic transport GO:1903651 82 0.263
kidney development GO:0001822 53 0.261
monocarboxylic acid transport GO:0015718 32 0.258
regulation of endothelial cell migration GO:0010594 67 0.258
regulation of leukocyte proliferation GO:0070663 67 0.258
negative regulation of hydrolase activity GO:0051346 182 0.256
regulation of actin polymerization or depolymerization GO:0008064 56 0.256
negative regulation of dna metabolic process GO:0051053 57 0.255
determination of adult lifespan GO:0008340 2 0.254
antigen receptor mediated signaling pathway GO:0050851 38 0.252
cell adhesion GO:0007155 325 0.245
neuromuscular junction development GO:0007528 3 0.242
regulation of organelle assembly GO:1902115 40 0.241
cellular response to nutrient levels GO:0031669 69 0.235
cellular response to cytokine stimulus GO:0071345 181 0.234
negative regulation of transferase activity GO:0051348 124 0.230
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.230
regulation of cell projection organization GO:0031344 107 0.228
exosomal secretion GO:1990182 15 0.226
fibroblast migration GO:0010761 7 0.225
positive regulation of cell substrate adhesion GO:0010811 37 0.224
regulation of notch signaling pathway GO:0008593 18 0.224
negative regulation of protein kinase activity GO:0006469 98 0.223
negative regulation of cellular catabolic process GO:0031330 83 0.217
response to inorganic substance GO:0010035 127 0.216
cellular response to inorganic substance GO:0071241 45 0.214
negative regulation of cellular protein metabolic process GO:0032269 353 0.214
response to cytokine GO:0034097 232 0.213
compound eye development GO:0048749 1 0.213
Fly
actin filament bundle organization GO:0061572 54 0.209
regulation of cellular response to stress GO:0080135 244 0.207
regulation of secretion by cell GO:1903530 177 0.204
extrinsic apoptotic signaling pathway GO:0097191 119 0.204
regulation of lipid metabolic process GO:0019216 96 0.204
cellular macromolecule catabolic process GO:0044265 380 0.203
myoblast fusion GO:0007520 1 0.199
lipid localization GO:0010876 106 0.196
regulation of protein localization GO:0032880 296 0.194
negative regulation of ras gtpase activity GO:0034261 6 0.194
regulation of cell migration GO:0030334 289 0.193
nitrogen compound transport GO:0071705 191 0.192
granulocyte differentiation GO:0030851 16 0.191
regulation of autophagy GO:0010506 52 0.190
focal adhesion assembly GO:0048041 30 0.190
positive regulation of lipid kinase activity GO:0090218 13 0.189
sensory perception GO:0007600 103 0.184
regulation of actin filament bundle assembly GO:0032231 36 0.184
actomyosin structure organization GO:0031032 59 0.184
ubiquitin dependent protein catabolic process GO:0006511 206 0.181
regulation of protein tyrosine kinase activity GO:0061097 36 0.181
innate immune response GO:0045087 178 0.180
regulation of cell activation GO:0050865 125 0.177
regulation of cell shape GO:0008360 48 0.177
nuclear transport GO:0051169 179 0.175
cell cell junction organization GO:0045216 69 0.174
neuron projection development GO:0031175 106 0.174
apoptotic signaling pathway GO:0097190 268 0.173
organic acid transport GO:0015849 65 0.173
negative regulation of phosphorus metabolic process GO:0010563 267 0.171
lipid modification GO:0030258 84 0.170
regulation of hormone secretion GO:0046883 57 0.169
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.169
establishment of spindle orientation GO:0051294 9 0.168
positive regulation of interferon gamma production GO:0032729 26 0.167
alcohol metabolic process GO:0006066 114 0.166
immune response GO:0006955 307 0.164
regulation of stress fiber assembly GO:0051492 32 0.164
growth of symbiont involved in interaction with host GO:0044116 2 0.163
secretion GO:0046903 254 0.162
chromatin assembly GO:0031497 61 0.161
positive regulation of cell activation GO:0050867 81 0.160
regulation of peptidase activity GO:0052547 180 0.159
zinc ion homeostasis GO:0055069 12 0.158
small molecule biosynthetic process GO:0044283 157 0.157
regulation of intracellular transport GO:0032386 195 0.156
regulation of b cell proliferation GO:0030888 18 0.155
immune response activating signal transduction GO:0002757 90 0.155
tissue homeostasis GO:0001894 63 0.152
response to endoplasmic reticulum stress GO:0034976 49 0.151
positive regulation of interferon gamma mediated signaling pathway GO:0060335 2 0.151
regulation of platelet aggregation GO:0090330 4 0.150
long term memory GO:0007616 2 0.149
regulation of cellular response to growth factor stimulus GO:0090287 76 0.147
positive regulation of cytokine production GO:0001819 167 0.145
positive regulation of proteolysis GO:0045862 142 0.145
regulation of cysteine type endopeptidase activity GO:2000116 127 0.142
regulation of alpha beta t cell activation GO:0046634 13 0.141
regulation of nucleotide metabolic process GO:0006140 269 0.141
cellular protein catabolic process GO:0044257 261 0.141
positive regulation of locomotion GO:0040017 186 0.140
negative regulation of epidermal growth factor activated receptor activity GO:0007175 6 0.140
response to extracellular stimulus GO:0009991 85 0.140
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.140
cellular hyperosmotic response GO:0071474 4 0.139
regulation of jun kinase activity GO:0043506 27 0.139
signal release GO:0023061 70 0.139
positive regulation of jun kinase activity GO:0043507 23 0.138
regulation of actin filament length GO:0030832 56 0.138
cell fate commitment GO:0045165 27 0.138
Fly
cellular response to salt stress GO:0071472 2 0.137
positive regulation of defense response GO:0031349 87 0.135
regulation of vesicle mediated transport GO:0060627 130 0.134
Fly
positive regulation of developmental process GO:0051094 314 0.134
regulation of myeloid cell differentiation GO:0045637 81 0.133
regulation of actin cytoskeleton reorganization GO:2000249 12 0.132
positive regulation of endothelial cell migration GO:0010595 39 0.131
establishment of protein localization to organelle GO:0072594 172 0.131
cell junction organization GO:0034330 79 0.131
receptor internalization GO:0031623 43 0.130
negative regulation of actin filament bundle assembly GO:0032232 9 0.130
immune response regulating signaling pathway GO:0002764 97 0.130
negative regulation of organelle organization GO:0010639 126 0.128
protein processing GO:0016485 226 0.127
dna conformation change GO:0071103 113 0.127
regulation of leukocyte activation GO:0002694 115 0.127
protein ubiquitination GO:0016567 314 0.127
peptidyl serine modification GO:0018209 106 0.126
response to other organism GO:0051707 261 0.125
protein catabolic process GO:0030163 325 0.125
negative regulation of protein homooligomerization GO:0032463 4 0.124
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.123
arachidonic acid secretion GO:0050482 7 0.122
small molecule catabolic process GO:0044282 92 0.121
cilium morphogenesis GO:0060271 75 0.120
vesicle localization GO:0051648 26 0.120
protein targeting to nucleus GO:0044744 104 0.119
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.116
establishment of synaptic vesicle localization GO:0097480 5 0.114
negative regulation of growth of symbiont involved in interaction with host GO:0044146 2 0.114
response to metal ion GO:0010038 84 0.113
inner ear morphogenesis GO:0042472 4 0.112
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.112
establishment of cell polarity GO:0030010 22 0.111
b cell receptor signaling pathway GO:0050853 18 0.111
regulation of interferon gamma production GO:0032649 36 0.110
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.110
neurogenesis GO:0022008 169 0.109
cell projection organization GO:0030030 252 0.109
activation of mapk activity GO:0000187 45 0.108
phagocytosis GO:0006909 42 0.107
receptor metabolic process GO:0043112 81 0.106
regulation of carbohydrate metabolic process GO:0006109 54 0.106
fatty acid metabolic process GO:0006631 115 0.105
cellular divalent inorganic cation homeostasis GO:0072503 128 0.102
hormone secretion GO:0046879 65 0.101
regulation of b cell differentiation GO:0045577 2 0.100
regulation of mapk cascade GO:0043408 262 0.100
cell type specific apoptotic process GO:0097285 125 0.100
macrophage activation involved in immune response GO:0002281 1 0.099
regulation of growth GO:0040008 165 0.099
response to starvation GO:0042594 59 0.098
modification dependent protein catabolic process GO:0019941 209 0.097
positive regulation of apoptotic process GO:0043065 246 0.097
carboxylic acid transport GO:0046942 63 0.097
regulation of ion homeostasis GO:2000021 73 0.096
single organism cell adhesion GO:0098602 179 0.096
lysosomal transport GO:0007041 33 0.094
negative regulation of multi organism process GO:0043901 92 0.094
regulation of immune response GO:0050776 201 0.093
cellular transition metal ion homeostasis GO:0046916 21 0.092
regulation of leukocyte differentiation GO:1902105 61 0.092
positive regulation of cell size GO:0045793 3 0.092
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.091
chromatin organization GO:0006325 351 0.090
viral budding GO:0046755 9 0.089
positive regulation of cell projection organization GO:0031346 64 0.089
synaptic vesicle transport GO:0048489 5 0.088
regulation of response to cytokine stimulus GO:0060759 46 0.087
sensory perception of sound GO:0007605 37 0.087
negative regulation of phosphate metabolic process GO:0045936 267 0.085
lymphocyte activation GO:0046649 133 0.085
regulation of neurotransmitter secretion GO:0046928 3 0.085
regulation of cell adhesion mediated by integrin GO:0033628 22 0.085
negative regulation of growth GO:0045926 97 0.085
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.083
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.083
phagolysosome assembly GO:0001845 5 0.083
calcium ion homeostasis GO:0055074 122 0.083
t cell receptor signaling pathway GO:0050852 21 0.082
cytokinesis GO:0000910 96 0.082
Fly
immune effector process GO:0002252 159 0.082
regulation of cell motility GO:2000145 299 0.082
negative regulation of cytoskeleton organization GO:0051494 45 0.082
sequestering of calcium ion GO:0051208 17 0.081
reactive oxygen species metabolic process GO:0072593 75 0.081
cellular homeostasis GO:0019725 196 0.080
dendritic spine maintenance GO:0097062 1 0.080
regulation of b cell activation GO:0050864 24 0.079
regulation of cell adhesion GO:0030155 166 0.078
programmed cell death in response to reactive oxygen species GO:0097468 4 0.078
epithelium migration GO:0090132 119 0.077
Fly
myeloid leukocyte activation GO:0002274 34 0.076
cell part morphogenesis GO:0032990 137 0.076
regulation of establishment of protein localization GO:0070201 242 0.076
regulation of response to external stimulus GO:0032101 222 0.076
positive regulation of fibroblast migration GO:0010763 3 0.076
photoreceptor cell differentiation GO:0046530 2 0.076
lytic vacuole organization GO:0080171 24 0.075
extracellular structure organization GO:0043062 41 0.075
Fly
regulation of protein polymerization GO:0032271 63 0.074
positive regulation of cdc42 gtpase activity GO:0043089 6 0.073
positive regulation of response to interferon gamma GO:0060332 2 0.072
metal ion homeostasis GO:0055065 169 0.071
positive regulation of wnt signaling pathway GO:0030177 54 0.071
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.071
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.071
positive regulation of innate immune response GO:0045089 79 0.070
secretion by cell GO:0032940 226 0.068
single organism membrane fusion GO:0044801 37 0.068
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.068
hexose metabolic process GO:0019318 55 0.067
muscle contraction GO:0006936 73 0.066
protein maturation GO:0051604 233 0.066
reproductive system development GO:0061458 56 0.066

SH3KBP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 40 1.000
Human
kidney disease DOID:557 36 0.999
Human
nephritis DOID:10952 6 0.894
Human
glomerulonephritis DOID:2921 6 0.894
Human
glomerulosclerosis DOID:0050851 6 0.894
Human
musculoskeletal system disease DOID:17 223 0.305
focal segmental glomerulosclerosis DOID:1312 6 0.194
Human