|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.793
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.673
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.657
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.589
|
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.540
|
|
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.517
|
|
|
|
ectodermal digestive tract development
|
GO:0007439 |
1 |
0.492
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.478
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.432
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.432
|
Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.419
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.417
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.391
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.380
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.343
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.342
|
Human |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.335
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
7 |
0.311
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.310
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.302
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.299
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.295
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.294
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.292
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.277
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.271
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.266
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.254
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.249
|
Human |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.238
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.219
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.211
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.207
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.197
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.186
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.184
|
Human |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.184
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.181
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.179
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.172
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.170
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.169
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.169
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.169
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.161
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.159
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.157
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.156
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.155
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.152
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.151
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.151
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.150
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.148
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.147
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.142
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.141
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.140
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.139
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.136
|
Fly |
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.135
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.135
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.132
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.131
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.124
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.124
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.123
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.123
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.122
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.121
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.120
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.120
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.112
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.111
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.111
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.110
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.107
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.104
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.103
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.100
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.100
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.100
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.098
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.098
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.098
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.097
|
Human |
|
|
lipid transport
|
GO:0006869 |
90 |
0.094
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.092
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.091
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.090
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.089
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.089
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.089
|
Human |
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.086
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.085
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.084
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.083
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.083
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.083
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.079
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.079
|
Fly |
|
|
regulation of intracellular estrogen receptor signaling pathway
|
GO:0033146 |
13 |
0.079
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.079
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.077
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.075
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.074
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.074
|
|
|
|
substrate independent telencephalic tangential migration
|
GO:0021826 |
0 |
0.074
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.073
|
|
|
|
contact inhibition
|
GO:0060242 |
3 |
0.073
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.073
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.073
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.072
|
Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.072
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.072
|
Fly |
|
|
sterol transport
|
GO:0015918 |
39 |
0.070
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.070
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.070
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
22 |
0.070
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.070
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.068
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.068
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.067
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.067
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.067
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.067
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.067
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.066
|
Fly |
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.065
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.065
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.063
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.063
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.062
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.062
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.061
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.061
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.061
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.060
|
|
|
|
ectodermal digestive tract morphogenesis
|
GO:0048567 |
1 |
0.060
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.060
|
|
|
|
negative regulation of posttranscriptional gene silencing
|
GO:0060149 |
3 |
0.059
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.059
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.058
|
Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.058
|
Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.058
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.058
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.057
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.056
|
Human |
|
|
negative regulation of gene silencing by rna
|
GO:0060967 |
3 |
0.056
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.055
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.055
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.054
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.054
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.054
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.053
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.052
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.052
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.052
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.052
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.051
|
|
|
|
regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis
|
GO:2001270 |
3 |
0.051
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.051
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.051
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.051
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.051
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.050
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.050
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.050
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.049
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.049
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.049
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.049
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.049
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.048
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.047
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.047
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.047
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.047
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.047
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.047
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.047
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.046
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.046
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.046
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.046
|
Fly |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.046
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.045
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.045
|
Fly |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.044
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.044
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.044
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.044
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.043
|
Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.043
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.042
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.042
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.042
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.042
|
Fly |
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.042
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.042
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.041
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.041
|
|
|
|
olfactory bulb development
|
GO:0021772 |
5 |
0.041
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.041
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.041
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.041
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.040
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.040
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.040
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.039
|
Human |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.039
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.039
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.039
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.039
|
Fly |
|
|
response to wounding
|
GO:0009611 |
168 |
0.039
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.039
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.039
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.038
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.038
|
|
|
|
olfactory bulb interneuron differentiation
|
GO:0021889 |
2 |
0.038
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.038
|
|
|
|
cochlea morphogenesis
|
GO:0090103 |
1 |
0.038
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.038
|
|
|
|
negative regulation of lamellipodium assembly
|
GO:0010593 |
2 |
0.038
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.037
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.037
|
Human |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.037
|
|
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
3 |
0.037
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.036
|
|
|
|
lymphocyte aggregation
|
GO:0071593 |
1 |
0.036
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.036
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.036
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.036
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.036
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.035
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.035
|
|
|
|
intracellular estrogen receptor signaling pathway
|
GO:0030520 |
23 |
0.035
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.035
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.035
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.035
|
Fly |
|
|
system process
|
GO:0003008 |
349 |
0.035
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.034
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.034
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.034
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.034
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.034
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.034
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.034
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.034
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.034
|
|
|
|
negative regulation of interleukin 23 production
|
GO:0032707 |
1 |
0.033
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.033
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.033
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.033
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.033
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.032
|
Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.032
|
Fly |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.032
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.032
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.031
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.031
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.031
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.031
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.031
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.031
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.030
|
|
|
|
sterol import
|
GO:0035376 |
4 |
0.030
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.030
|
|
|
|
negative regulation of lamellipodium organization
|
GO:1902744 |
4 |
0.030
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.030
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.030
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.030
|
Human |
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.030
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.030
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.030
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.030
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.030
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.029
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.029
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.029
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.029
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.029
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.029
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.028
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.028
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.028
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.027
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.027
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.027
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.027
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.027
|
|
|
|
growth
|
GO:0040007 |
202 |
0.027
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.027
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.026
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.026
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.026
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.026
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.026
|
Fly |
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.026
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.026
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.026
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.026
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.026
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.025
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.025
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.025
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.025
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.025
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.025
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.025
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.025
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.025
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.025
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.024
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.024
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.024
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.024
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
4 |
0.024
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.024
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.024
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.024
|
Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.024
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.024
|
Human |
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.024
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.024
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.024
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.024
|
Fly |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.024
|
Human |
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.024
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.023
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.023
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.023
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.023
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.023
|
Human Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.023
|
|
|
|
substrate independent telencephalic tangential interneuron migration
|
GO:0021843 |
0 |
0.023
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.022
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.022
|
|
|
|
embryonic ectodermal digestive tract development
|
GO:0048611 |
1 |
0.022
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.022
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.022
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.022
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.022
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.022
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.022
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.022
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.022
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.022
|
|
|
|
myoblast proliferation
|
GO:0051450 |
1 |
0.022
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.022
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.022
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.022
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.021
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.021
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.021
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.021
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.021
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.021
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.021
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.021
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.021
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.021
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.021
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.021
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.021
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.021
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.020
|
Fly |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.020
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.020
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.020
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.020
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.020
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.020
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.020
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.020
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.020
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.020
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.020
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.020
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.019
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.019
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.019
|
Fly |
|
|
long term memory
|
GO:0007616 |
2 |
0.019
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.019
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.019
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.019
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.019
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.019
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.019
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.019
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.019
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.019
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.019
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.019
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.019
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.019
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.018
|
|
|
|
olfactory lobe development
|
GO:0021988 |
5 |
0.018
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.018
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.018
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.018
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.018
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.018
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.018
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.018
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.018
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.018
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.018
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.018
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.018
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
14 |
0.018
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.017
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.017
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.017
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.017
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.017
|
Fly |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.017
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.017
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.017
|
|
|
|
memory
|
GO:0007613 |
3 |
0.017
|
|
|
|
positive regulation of lamellipodium assembly
|
GO:0010592 |
9 |
0.017
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.017
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.017
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.017
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.017
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.017
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.017
|
|
|
|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.017
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.017
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.017
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.016
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.016
|
|
|
|
embryonic ectodermal digestive tract morphogenesis
|
GO:0048613 |
1 |
0.016
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.016
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.016
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.016
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.016
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.016
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.016
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.016
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.016
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.016
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.016
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.016
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.016
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.016
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.016
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.016
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.016
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.016
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.016
|
Fly |
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.016
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.015
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.015
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.015
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.015
|
Human |
|
|
nuclear division
|
GO:0000280 |
128 |
0.015
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.015
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.015
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.015
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.015
|
Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.015
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.015
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.015
|
Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.015
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.015
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.015
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.015
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.015
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.014
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.014
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.014
|
Fly |
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.014
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.014
|
|
|
|
interleukin 23 production
|
GO:0032627 |
5 |
0.014
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.014
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.014
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.014
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.014
|
Fly |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.014
|
|
