|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.978
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.968
|
Fly |
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.964
|
|
|
|
regulation of vasculogenesis
|
GO:2001212 |
3 |
0.929
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.853
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.748
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.686
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.676
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.657
|
|
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.650
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.594
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.557
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.540
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.497
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.492
|
|
|
|
positive regulation of vasculogenesis
|
GO:2001214 |
1 |
0.483
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.480
|
Human |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.467
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.457
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.443
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.440
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.436
|
|
|
|
chemical homeostasis within a tissue
|
GO:0048875 |
3 |
0.433
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.413
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.392
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.389
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.388
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.387
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.383
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.375
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.353
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.353
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.333
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.321
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.320
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.313
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.308
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.308
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.304
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.303
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.299
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.292
|
Fly |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.287
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.286
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.279
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.273
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.271
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.268
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.264
|
|
|
|
surfactant homeostasis
|
GO:0043129 |
3 |
0.264
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.247
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.247
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.241
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.237
|
|
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.236
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.230
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.226
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.224
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.223
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.222
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.219
|
Human |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.211
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.209
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.207
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.204
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.199
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.198
|
Fly |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.198
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.197
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.194
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.193
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.190
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.190
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.189
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.188
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.188
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.186
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.185
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.184
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.182
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.181
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.180
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.176
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.173
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.172
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.172
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.172
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.170
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.170
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.169
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.167
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.167
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.165
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.164
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.164
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.163
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.160
|
Human |
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.155
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.153
|
Fly |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.152
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.150
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.148
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.146
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.144
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.144
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.143
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.141
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.141
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.140
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.140
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.139
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.138
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.137
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.136
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.136
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.136
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.136
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.136
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.135
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.134
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.133
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.133
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.132
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.131
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.131
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.130
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.129
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.129
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.129
|
|
|
|
fc receptor signaling pathway
|
GO:0038093 |
2 |
0.128
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.127
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.127
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.127
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.126
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.125
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.124
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.123
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.123
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.121
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.120
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.120
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.119
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.118
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.118
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.116
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.115
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.114
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.113
|
|
|
|
male gonad development
|
GO:0008584 |
23 |
0.112
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.111
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.110
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.109
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.108
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.106
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.105
|
|
|
|
response to macrophage colony stimulating factor
|
GO:0036005 |
4 |
0.104
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.104
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.103
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.103
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.101
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.101
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.101
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.100
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.099
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.094
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.093
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.093
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.092
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.092
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.091
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.091
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.091
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.090
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.089
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.089
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.089
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.088
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.088
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.087
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.087
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.086
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.086
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.085
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.084
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.084
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.082
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.082
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.081
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.081
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.081
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.080
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.080
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.079
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.079
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.079
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.078
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.078
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.078
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.077
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.076
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.076
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.075
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.074
|
|
|
|
ovulation cycle
|
GO:0042698 |
9 |
0.074
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.073
|
Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.073
|
Human |
|
|
response to stem cell factor
|
GO:0036215 |
1 |
0.073
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.072
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.072
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
1 |
0.072
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.072
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.071
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.071
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.071
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.070
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.070
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.070
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.069
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.069
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.069
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.069
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.069
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.069
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.069
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
7 |
0.068
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.067
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.067
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.067
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.066
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.066
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.066
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.065
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.065
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.064
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.063
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.063
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.063
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.062
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.062
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.061
|
|
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.061
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.061
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.060
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.060
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.060
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.059
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.059
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.059
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.059
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.059
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.057
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.057
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.057
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.057
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.057
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.056
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.056
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.056
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.055
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.055
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.055
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.055
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.054
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.053
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.053
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.053
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.053
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.053
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.052
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.051
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.051
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.051
|
Human |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.051
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.051
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.051
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.050
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.049
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.049
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.049
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.047
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.047
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.047
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.047
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.046
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.046
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.046
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.046
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.045
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.045
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.045
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.045
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.045
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.045
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.045
|
|
|
|
ovulation cycle process
|
GO:0022602 |
9 |
0.044
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.044
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.044
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.044
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.044
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.044
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.043
|
|
|
|
regulation of phosphoprotein phosphatase activity
|
GO:0043666 |
23 |
0.043
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.043
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
40 |
0.043
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.043
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.043
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.042
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.042
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.042
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.042
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.042
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.041
|
|
|
|
regulation of hematopoietic progenitor cell differentiation
|
GO:1901532 |
24 |
0.040
|
|
|
|
positive regulation vascular endothelial growth factor production
|
GO:0010575 |
12 |
0.040
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.040
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.040
|
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.039
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.039
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.039
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.039
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.039
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.039
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.039
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.039
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.039
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.038
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.038
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.038
|
|
|
|
respiratory tube development
|
GO:0030323 |
20 |
0.038
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.038
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.038
|
|
|
|
growth
|
GO:0040007 |
202 |
0.038
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.038
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.038
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.038
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.038
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.037
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.037
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.036
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.036
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.036
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.036
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.035
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.035
|
|
|
|
cellular response to stem cell factor stimulus
|
GO:0036216 |
1 |
0.035
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.035
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.035
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.035
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.035
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.035
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.035
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.035
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.035
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.035
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.034
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.034
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.034
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.034
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.034
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.033
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.033
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.033
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.033
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.033
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.033
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.033
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.033
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.032
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.032
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.032
|
|
|
|
memory
|
GO:0007613 |
3 |
0.032
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.032
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.031
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.031
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.031
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.031
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.031
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.031
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.031
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.030
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.030
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.030
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.030
|
|
|
|
ovarian follicle development
|
GO:0001541 |
5 |
0.030
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.030
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.030
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.030
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.030
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.030
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.030
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.030
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.030
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.029
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.029
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.029
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.029
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.029
|
|
|
|
mast cell cytokine production
|
GO:0032762 |
1 |
0.029
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.028
|
|
|
|
negative regulation of coagulation
|
GO:0050819 |
24 |
0.028
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.028
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.028
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.028
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.028
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.028
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.028
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.028
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.028
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.027
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.027
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.027
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.027
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.027
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.027
|
|
|
|
regulation of nitric oxide synthase biosynthetic process
|
GO:0051769 |
6 |
0.027
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.027
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.027
|
|
|
|
regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030947 |
9 |
0.027
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.026
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
10 |
0.026
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.026
|
|
|
|
regulation of protein kinase c signaling
|
GO:0090036 |
8 |
0.026
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.026
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.026
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.026
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.026
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.025
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.025
|
|
|
|
cell cell junction maintenance
|
GO:0045217 |
4 |
0.025
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
26 |
0.025
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.025
|
|
|
|
kit signaling pathway
|
GO:0038109 |
1 |
0.025
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.025
|
|
|
|
chemokine secretion
|
GO:0090195 |
7 |
0.025
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.025
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.025
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.025
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.024
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.024
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.024
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.024
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.024
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.024
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.024
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.024
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.024
|
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
19 |
0.024
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
13 |
0.023
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.023
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.023
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.023
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.023
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.023
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.023
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.023
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.023
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.023
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.023
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.023
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.023
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.023
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.023
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.022
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.022
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.022
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.022
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.022
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.022
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.022
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.022
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.021
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.021
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.021
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.021
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.021
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.021
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.021
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.021
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.021
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.021
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.021
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.021
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.021
|
|
|
|
negative regulation of calcium mediated signaling
|
GO:0050849 |
4 |
0.021
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
15 |
0.021
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.021
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.021
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
5 |
0.020
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.020
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.020
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.020
|
|
