|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.827
|
|
|
|
positive regulation of renal albumin absorption
|
GO:2000534 |
1 |
0.777
|
|
|
|
complement component c5a signaling pathway
|
GO:0038178 |
1 |
0.670
|
|
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
3 |
0.588
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.577
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.566
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.556
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.538
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.520
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.502
|
|
|
|
regulation of aldosterone secretion
|
GO:2000858 |
1 |
0.468
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.461
|
|
|
|
positive regulation of monocyte chemotactic protein 1 production
|
GO:0071639 |
3 |
0.458
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.458
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.444
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.415
|
|
|
|
aldosterone secretion
|
GO:0035932 |
1 |
0.411
|
|
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
3 |
0.393
|
|
|
|
positive regulation of corticosteroid hormone secretion
|
GO:2000848 |
5 |
0.387
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
2 |
0.375
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.371
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.368
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.362
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.356
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.345
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.340
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.339
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.333
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.324
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.318
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.312
|
|
|
|
negative regulation of macrophage differentiation
|
GO:0045650 |
2 |
0.311
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.310
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
2 |
0.286
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.285
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.283
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.277
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.275
|
|
|
|
negative regulation of low density lipoprotein particle receptor biosynthetic process
|
GO:0045715 |
3 |
0.270
|
|
|
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
4 |
0.266
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.265
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.256
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.252
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.251
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.246
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.246
|
|
|
|
negative regulation of t cell cytokine production
|
GO:0002725 |
4 |
0.244
|
|
|
|
regulation of mineralocorticoid secretion
|
GO:2000855 |
1 |
0.242
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.235
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.234
|
|
|
|
establishment of t cell polarity
|
GO:0001768 |
2 |
0.231
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.231
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.225
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.222
|
|
|
|
granzyme b production
|
GO:0071613 |
1 |
0.221
|
|
|
|
regulation of renal albumin absorption
|
GO:2000532 |
1 |
0.220
|
|
|
|
regulation of macrophage chemotaxis
|
GO:0010758 |
4 |
0.219
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.215
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.213
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.209
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.209
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.203
|
|
|
|
negative regulation of cd8 positive alpha beta t cell activation
|
GO:2001186 |
1 |
0.201
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.199
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.199
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.195
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.194
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.193
|
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.193
|
|
|
|
mineralocorticoid secretion
|
GO:0035931 |
1 |
0.189
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.188
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.187
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.187
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.185
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.182
|
|
|
|
renal protein absorption
|
GO:0097017 |
1 |
0.181
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.179
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.178
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.176
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.173
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.171
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.171
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.170
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
18 |
0.165
|
|
|
|
negative regulation of homotypic cell cell adhesion
|
GO:0034111 |
3 |
0.163
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.162
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.162
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.161
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.160
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.160
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.158
|
|
|
|
negative regulation of lymphocyte migration
|
GO:2000402 |
4 |
0.157
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.157
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.156
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.153
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.152
|
|
|
|
eosinophil activation
|
GO:0043307 |
3 |
0.151
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.150
|
|
|
|
renal albumin absorption
|
GO:0097018 |
1 |
0.150
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.150
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.147
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.147
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.144
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.144
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.143
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.143
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.143
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.143
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.142
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.140
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.138
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.138
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.137
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.136
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.135
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.134
|
|
|
|
regulation of chemokine mediated signaling pathway
|
GO:0070099 |
6 |
0.130
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.130
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.129
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.128
|
|
|
|
positive regulation of aldosterone secretion
|
GO:2000860 |
1 |
0.128
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.126
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.126
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.125
|
|
|
|
negative regulation of t helper 1 cell activation
|
GO:2000518 |
1 |
0.124
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.122
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.121
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.120
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.120
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.120
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.120
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.118
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.116
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.116
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.115
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.115
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.114
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.113
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.113
|
|
|
|
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:2001189 |
1 |
0.113
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.112
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.112
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.112
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.112
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.112
|
|
|
|
negative regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000562 |
1 |
0.111
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.111
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.109
|
|
|
|
regulation of granzyme a production
|
GO:2000511 |
1 |
0.109
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.106
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.105
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.104
|
|
|
|
negative regulation of c c chemokine binding
|
GO:2001264 |
1 |
0.104
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.102
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
1 |
0.101
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.100
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
2 |
0.100
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.100
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.097
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.097
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.097
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.096
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.095
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.095
|
|
|
|
complement activation classical pathway
|
GO:0006958 |
3 |
0.094
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.094
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.093
|
|
|
|
positive regulation of steroid hormone secretion
|
GO:2000833 |
6 |
0.092
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.092
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.091
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.091
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.091
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.090
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.090
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.090
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.089
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.089
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.089
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.088
|
|
|
|
positive regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000566 |
1 |
0.086
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.086
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.086
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.084
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.084
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.083
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.083
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.083
|
Mouse |
|
|
myeloid dendritic cell chemotaxis
|
GO:0002408 |
3 |
0.082
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.082
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.082
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.081
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.078
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.078
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.078
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.078
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.078
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.078
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.077
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.077
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.077
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.077
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.077
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.076
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.075
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.075
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.075
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.075
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.075
|
|
|
|
serotonin secretion
|
GO:0001820 |
1 |
0.074
|
|
|
|
type i interferon secretion
|
GO:0072641 |
1 |
0.074
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.074
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.074
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.073
|
|
|
|
granzyme a production
|
GO:0035746 |
1 |
0.073
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.073
|
|
|
|
negative regulation of smooth muscle cell migration
|
GO:0014912 |
7 |
0.072
|
|
|
|
negative regulation of viral genome replication
|
GO:0045071 |
35 |
0.072
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.072
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.071
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.071
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.071
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.071
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.071
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.070
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.070
|
|
|
|
negative regulation of natural killer cell chemotaxis
|
GO:2000502 |
1 |
0.069
|
|
|
|
positive regulation of cell cell adhesion mediated by integrin
|
GO:0033634 |
3 |
0.069
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.069
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.068
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.068
|
|
|
|
negative regulation of coagulation
|
GO:0050819 |
24 |
0.068
|
|
|
|
regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000561 |
2 |
0.068
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.067
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.067
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.067
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.067
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.067
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.067
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.066
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.066
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.065
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.065
|
|
|
|
positive regulation of protein kinase a signaling
|
GO:0010739 |
4 |
0.065
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.065
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
2 |
0.064
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.064
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.064
|
Mouse |
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
2 |
0.063
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.063
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.062
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.062
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
4 |
0.062
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.061
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.061
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.061
|
|
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.060
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.060
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.060
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.060
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.059
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.058
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.058
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.058
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.057
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.057
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.057
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.057
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.056
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.056
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.056
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.056
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.056
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.055
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
4 |
0.055
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.055
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.055
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.054
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.054
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.054
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.054
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.054
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.054
|
|
|
|
regulation of sensory perception
|
GO:0051931 |
3 |
0.053
|
|
|
|
regulation of corticosteroid hormone secretion
|
GO:2000846 |
5 |
0.053
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.053
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.053
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.053
|
|
|
|
regulation of gamma delta t cell activation involved in immune response
|
GO:2001191 |
1 |
0.053
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.053
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.053
|
|
|
|
activation of phospholipase d activity
|
GO:0031584 |
3 |
0.052
|
|
|
|
plasma lipoprotein particle clearance
|
GO:0034381 |
16 |
0.052
|
|
|
|
system process
|
GO:0003008 |
349 |
0.052
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.051
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.051
|
|
|
|
eosinophil chemotaxis
|
GO:0048245 |
8 |
0.051
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
8 |
0.051
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.051
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.051
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.050
|
|
|
|
viral genome replication
|
GO:0019079 |
50 |
0.050
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.050
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.050
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.050
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.049
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.049
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.049
|
|
|
|
regulation of viral genome replication
|
GO:0045069 |
48 |
0.049
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.048
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.048
|
|
|
|
positive regulation of homotypic cell cell adhesion
|
GO:0034112 |
4 |
0.048
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.048
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.047
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.047
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.047
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
20 |
0.047
|
|
|
|
regulation of c c chemokine binding
|
GO:2001263 |
1 |
0.047
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.047
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.046
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.046
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.046
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.046
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.046
|
|
|
|
monocyte chemotactic protein 1 production
|
GO:0071605 |
6 |
0.046
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.045
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.045
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.045
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.045
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.045
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.045
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.045
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.045
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.044
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.044
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.044
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.044
|
|
|
|
regulation of heterotypic cell cell adhesion
|
GO:0034114 |
14 |
0.044
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.044
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
20 |
0.043
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
16 |
0.043
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.043
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.043
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.043
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.043
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.043
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.042
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.042
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.042
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.042
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.042
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
16 |
0.042
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.041
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.041
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.041
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.041
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.041
|
|
|
|
negative regulation of lymphocyte chemotaxis
|
GO:1901624 |
2 |
0.041
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.041
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
19 |
0.041
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.040
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.040
|
Mouse |
|
|
serotonin transport
|
GO:0006837 |
3 |
0.040
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
7 |
0.040
|
|
|
|
immune response in mucosal associated lymphoid tissue
|
GO:0002386 |
1 |
0.040
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.040
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.040
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.040
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.040
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.040
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.039
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.039
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.039
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.039
|
|
|
|
regulation of t helper 1 cell activation
|
GO:2000517 |
1 |
0.038
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.038
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.038
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.038
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.038
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.038
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.037
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.037
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.037
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.037
|
|
|
|
negative regulation of leukocyte migration
|
GO:0002686 |
14 |
0.037
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.037
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.037
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.037
|
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.037
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.036
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.036
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.036
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.036
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.036
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.036
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.036
|
|
|
|
regulation of osteoclast development
|
GO:2001204 |
1 |
0.036
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.036
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.035
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.035
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.035
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.035
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.035
|
|
|
|
regulation of plasma lipoprotein particle levels
|
GO:0097006 |
32 |
0.035
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.035
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.034
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.034
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.034
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.034
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.034
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.033
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.033
|
|
|
|
regulation of sensory perception of pain
|
GO:0051930 |
3 |
0.033
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.033
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.032
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.032
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.032
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.032
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.032
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.032
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.032
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.031
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.031
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.031
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.031
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.031
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.031
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.031
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.031
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.031
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.031
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.031
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.031
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
1 |
0.031
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
22 |
0.030
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.030
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.030
|
|
|
|
cell killing
|
GO:0001906 |
34 |
0.030
|
|
|
|
establishment of lymphocyte polarity
|
GO:0001767 |
2 |
0.030
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.030
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.030
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.030
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.030
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.030
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.030
|
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.030
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.029
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.029
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.029
|
|
|
|
negative regulation of chemokine mediated signaling pathway
|
GO:0070100 |
5 |
0.029
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
16 |
0.029
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
6 |
0.029
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.029
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.029
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.029
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.029
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.029
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.029
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.028
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.028
|
|
|
|
negative regulation of transforming growth factor beta secretion
|
GO:2001202 |
1 |
0.028
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.028
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.028
|
|
|
|
eosinophil migration
|
GO:0072677 |
10 |
0.028
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.028
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.028
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.028
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.028
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.028
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
1 |
0.027
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.027
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.027
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.027
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
4 |
0.027
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.027
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.027
|
Mouse |
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.027
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
5 |
0.027
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.027
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.027
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.027
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.027
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.027
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
4 |
0.027
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.027
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.027
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.027
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.027
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
1 |
0.027
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.026
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.026
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.026
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.026
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.026
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.026
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.026
|
|
|
|
t helper 1 cell activation
|
GO:0035711 |
1 |
0.026
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.026
|
|
|
|
negative regulation of hemostasis
|
GO:1900047 |
22 |
0.026
|
|
