|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
histone modification
|
GO:0016570 |
251 |
1.000
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
1.000
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
1.000
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
1.000
|
|
|
|
nucleosome positioning
|
GO:0016584 |
3 |
1.000
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.999
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.999
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.999
|
Yeast Worm |
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.999
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.999
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.997
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.997
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.996
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.996
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.995
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.995
|
|
|
|
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072361 |
2 |
0.994
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.994
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.994
|
|
|
|
heat acclimation
|
GO:0010286 |
3 |
0.994
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.993
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
3 |
0.988
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.987
|
|
|
|
atp dependent chromatin remodeling
|
GO:0043044 |
25 |
0.986
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.985
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.984
|
Worm |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.981
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.978
|
Yeast |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.975
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.973
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.972
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.971
|
|
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.971
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.970
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.969
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.967
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.963
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.961
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.961
|
|
|
|
cellular heat acclimation
|
GO:0070370 |
3 |
0.959
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.957
|
|
|
|
definitive erythrocyte differentiation
|
GO:0060318 |
2 |
0.956
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.956
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.954
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.950
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.947
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.946
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.941
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
5 |
0.941
|
Yeast |
|
|
nervous system development
|
GO:0007399 |
293 |
0.932
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.930
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.929
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.924
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.923
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.911
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.910
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.902
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.899
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.890
|
Mouse |
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.884
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.881
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.870
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.868
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.863
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.859
|
Yeast |
|
|
immune system development
|
GO:0002520 |
195 |
0.852
|
Mouse |
|
|
thalamus development
|
GO:0021794 |
2 |
0.852
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.846
|
Fly |
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.838
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.825
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.824
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.824
|
Fly |
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.824
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.816
|
Fly |
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.813
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.799
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.798
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.796
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.795
|
Fly |
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.789
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.788
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.787
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.781
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.776
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.775
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
12 |
0.775
|
|
|
|
histone h4 deacetylation
|
GO:0070933 |
8 |
0.751
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.750
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.749
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.748
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.742
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.741
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.738
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.736
|
Fly |
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.726
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
15 |
0.712
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.702
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.701
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.698
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.696
|
|
|
|
tongue development
|
GO:0043586 |
1 |
0.691
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.690
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.680
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
1 |
0.679
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.674
|
Worm |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.672
|
Worm Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.670
|
Mouse |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.668
|
|
|
|
eyelid development in camera type eye
|
GO:0061029 |
2 |
0.668
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.662
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.656
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.655
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.655
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.651
|
|
|
|
release from viral latency
|
GO:0019046 |
1 |
0.650
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.645
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.641
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.632
|
Fly |
|
|
camera type eye morphogenesis
|
GO:0048593 |
12 |
0.630
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.629
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.620
|
Worm |
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.605
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.599
|
|
|
|
embryonic digestive tract development
|
GO:0048566 |
10 |
0.596
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.594
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.593
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.589
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.583
|
|
|
|
cellular carbohydrate catabolic process
|
GO:0044275 |
17 |
0.571
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.569
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
6 |
0.568
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.568
|
Yeast |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.566
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.565
|
|
|
|
type 2 immune response
|
GO:0042092 |
6 |
0.560
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.552
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.541
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.539
|
|
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.525
|
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.520
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.518
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.515
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.514
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.510
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.509
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.508
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.507
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.506
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.505
|
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.502
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.497
|
Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.495
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.490
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
11 |
0.485
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.483
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.475
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.471
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.470
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.468
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.467
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.462
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.461
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.459
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.457
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.452
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.450
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.439
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.438
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.437
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.422
|
|
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
10 |
0.421
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.418
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.415
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.413
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.413
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.412
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.410
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.408
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.404
|
Mouse Fly |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.404
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.400
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.400
|
|
|
|
negative regulation of peptidyl lysine acetylation
|
GO:2000757 |
8 |
0.399
|
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.399
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.397
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.394
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.380
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.375
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
26 |
0.368
|
|
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.366
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.366
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.363
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.363
|
|
|
|
positive regulation of t helper cell differentiation
|
GO:0045624 |
2 |
0.362
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.361
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.361
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.358
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.355
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.348
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.342
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.340
|
|
|
|
negative regulation of myotube differentiation
|
GO:0010832 |
4 |
0.334
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.331
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.328
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.327
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.321
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.321
|
Yeast |
|
|
cell activation
|
GO:0001775 |
213 |
0.320
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.319
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.319
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.316
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.315
|
|
|
|
cellular respiration
|
GO:0045333 |
21 |
0.314
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.310
|
Fly |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.308
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.307
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.305
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.304
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.304
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.304
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.301
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.300
|
|
|
|
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902177 |
4 |
0.297
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.297
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.291
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.290
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.288
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.287
|
|
|
|
nucleosome assembly
|
GO:0006334 |
50 |
0.282
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.278
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.275
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.274
|
|
|
|
positive regulation of axonogenesis
|
GO:0050772 |
9 |
0.274
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.273
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.271
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
4 |
0.269
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.268
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.267
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.261
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.259
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.258
|
Yeast |
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.258
|
Worm |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.257
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.250
|
|
|
|
histone h4 k8 acetylation
|
GO:0043982 |
15 |
0.249
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.245
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
5 |
0.243
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.242
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.242
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.240
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.240
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.239
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.238
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.235
|
Worm |
|
|
growth
|
GO:0040007 |
202 |
0.233
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.233
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.231
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.231
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.230
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.230
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.228
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.226
|
|
|
|
intracellular bile acid receptor signaling pathway
|
GO:0038185 |
1 |
0.225
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.223
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.223
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.222
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.220
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
27 |
0.218
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.218
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.217
|
Mouse |
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.216
|
|
|
|
negative regulation of chromatin silencing at rdna
|
GO:0061188 |
2 |
0.216
|
Yeast |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.216
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.215
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.212
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.211
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.211
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.210
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.210
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.207
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.206
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.206
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.203
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.201
|
Fly |
|
|
regulation of sarcomere organization
|
GO:0060297 |
3 |
0.200
|
|
|
|
dna replication dependent nucleosome assembly
|
GO:0006335 |
32 |
0.200
|
|
|
|
single stranded viral rna replication via double stranded dna intermediate
|
GO:0039692 |
9 |
0.200
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.199
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.197
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.192
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
15 |
0.192
|
|
|
|
histone h4 k5 acetylation
|
GO:0043981 |
15 |
0.190
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.189
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.187
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.187
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.186
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.184
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.184
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.184
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.183
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.179
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.179
|
|
|
|
nose development
|
GO:0043584 |
2 |
0.179
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.178
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.178
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.175
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.175
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.174
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.172
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.172
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.171
|
Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.168
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.168
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.168
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.166
|
Fly |
|
|
embryonic limb morphogenesis
|
GO:0030326 |
9 |
0.166
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.165
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.165
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.164
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.163
|
Fly |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.160
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
7 |
0.159
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.159
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.158
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.157
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.157
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.155
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.155
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.152
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.152
|
|
|
|
regulation of cellular carbohydrate catabolic process
|
GO:0043471 |
11 |
0.151
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.150
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.149
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.147
|
Fly |
|
|
memory
|
GO:0007613 |
3 |
0.147
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.147
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.145
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.145
|
Worm Fly |
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.145
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.141
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.138
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.136
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.136
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.136
|
Mouse Worm |
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.136
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
7 |
0.136
|
|
|
|
positive regulation of axon extension involved in axon guidance
|
GO:0048842 |
1 |
0.135
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.134
|
|
|
|
interaction with symbiont
|
GO:0051702 |
26 |
0.134
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.134
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.133
|
|
|
|
erythrocyte development
|
GO:0048821 |
3 |
0.131
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.130
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.127
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
3 |
0.127
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.126
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.125
|
|
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
15 |
0.125
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.125
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.125
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.121
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.120
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.119
|
|
|
|
regulation of glycolytic process
|
GO:0006110 |
10 |
0.116
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.116
|
|
|
|
negative regulation of histone acetylation
|
GO:0035067 |
6 |
0.116
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.114
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.113
|
|
|
|
protein heterotrimerization
|
GO:0070208 |
4 |
0.113
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.112
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.112
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.111
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.111
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.111
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.110
|
|
|
|
regulation of histone methylation
|
GO:0031060 |
16 |
0.110
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.110
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.109
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.108
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.107
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
5 |
0.107
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.106
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.106
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.105
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.105
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.105
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.104
|
Yeast Mouse |
|
|
long term memory
|
GO:0007616 |
2 |
0.103
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
8 |
0.102
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.102
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.101
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.100
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.100
|
Mouse |
|
|
response to virus
|
GO:0009615 |
126 |
0.099
|
|
|
|
negative regulation of bile acid biosynthetic process
|
GO:0070858 |
3 |
0.099
|
|
|
|
melanocyte differentiation
|
GO:0030318 |
2 |
0.099
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.099
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.098
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.098
|
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
10 |
0.098
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.097
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.096
|
|
|
|
negative regulation of protein acetylation
|
GO:1901984 |
11 |
0.095
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.095
|
|
|
|
dna replication dependent nucleosome organization
|
GO:0034723 |
32 |
0.095
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.094
|
|
|
|
glycolytic process
|
GO:0006096 |
17 |
0.094
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.094
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.093
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
9 |
0.093
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.092
|
|
|
|
positive regulation of anoikis
|
GO:2000210 |
4 |
0.090
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.090
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.089
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.089
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.089
|
Fly |
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.088
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.088
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.088
|
|
|
|
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903376 |
7 |
0.087
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.087
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.087
|
|
|
|
positive regulation of histone h3 k4 methylation
|
GO:0051571 |
8 |
0.087
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.086
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.085
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.085
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.085
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.085
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.085
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.085
|
|
|
|
dna replication independent nucleosome organization
|
GO:0034724 |
27 |
0.084
|
|
|
|
hair follicle placode formation
|
GO:0060789 |
1 |
0.084
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.084
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.084
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.083
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.083
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.082
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.081
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.081
|
Fly |
|
|
chromatin remodeling at centromere
|
GO:0031055 |
2 |
0.081
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.081
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.080
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.080
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.079
|
|
|
|
positive regulation of chromatin silencing
|
GO:0031937 |
3 |
0.079
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.079
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.079
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.079
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.079
|
|
|
|
negative regulation of immunoglobulin mediated immune response
|
GO:0002890 |
3 |
0.078
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.078
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.078
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.077
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
1 |
0.076
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.076
|
Yeast |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.076
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.076
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.075
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.075
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.075
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.074
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.074
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.074
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.074
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.074
|
Yeast |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.073
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.073
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.072
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.072
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.071
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.071
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.071
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.070
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.070
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.070
|
Yeast |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.070
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
0.069
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.069
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.067
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
15 |
0.067
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.067
|
|
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
0.067
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.067
|
Yeast |
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.066
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.066
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
18 |
0.066
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.066
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.066
|
|
