Homo sapiens

89 known processes

SIX3

SIX homeobox 3

(Aliases: HPE2)

SIX3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.807
forebrain generation of neurons GO:0021872 3 0.422
spinal cord development GO:0021510 4 0.347
negative regulation of multicellular organismal process GO:0051241 317 0.320
hindbrain development GO:0030902 3 0.306
organ morphogenesis GO:0009887 147 0.305
Fly
regulation of cell differentiation GO:0045595 393 0.291
nervous system development GO:0007399 293 0.279
system process GO:0003008 349 0.259
neuron differentiation GO:0030182 138 0.255
Fly
inner ear morphogenesis GO:0042472 4 0.245
cell morphogenesis GO:0000902 296 0.236
Fly
brain development GO:0007420 97 0.234
cell development GO:0048468 328 0.229
Fly
circulatory system development GO:0072359 262 0.227
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.227
forelimb morphogenesis GO:0035136 4 0.219
cell fate determination GO:0001709 3 0.215
organ formation GO:0048645 3 0.206
anatomical structure formation involved in morphogenesis GO:0048646 284 0.199
positive regulation of cell proliferation GO:0008284 301 0.195
cell cell signaling GO:0007267 155 0.194
pituitary gland development GO:0021983 2 0.189
regulation of locomotion GO:0040012 329 0.187
cardiovascular system development GO:0072358 262 0.181
regulation of cellular component movement GO:0051270 334 0.180
response to oxygen containing compound GO:1901700 369 0.173
cellular component morphogenesis GO:0032989 314 0.170
Fly
generation of neurons GO:0048699 152 0.170
Fly
central nervous system development GO:0007417 123 0.169
cell projection organization GO:0030030 252 0.169
Fly
regulation of cell migration GO:0030334 289 0.166
regulation of cellular amino acid metabolic process GO:0006521 6 0.162
regulation of cellular amine metabolic process GO:0033238 11 0.157
positive regulation of cell differentiation GO:0045597 211 0.154
positive regulation of developmental process GO:0051094 314 0.153
forebrain neuron differentiation GO:0021879 3 0.152
cellular amino acid metabolic process GO:0006520 116 0.151
cell morphogenesis involved in differentiation GO:0000904 144 0.150
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.149
cranial nerve development GO:0021545 4 0.145
amine metabolic process GO:0009308 44 0.144
embryonic morphogenesis GO:0048598 85 0.142
positive regulation of cellular amine metabolic process GO:0033240 7 0.139
regulation of neuron differentiation GO:0045664 70 0.137
negative regulation of developmental process GO:0051093 247 0.137
epithelium development GO:0060429 227 0.137
neuron projection development GO:0031175 106 0.135
Fly
secretion by cell GO:0032940 226 0.135
regulation of cell motility GO:2000145 299 0.135
forebrain dorsal ventral pattern formation GO:0021798 1 0.135
regulation of cellular ketone metabolic process GO:0010565 50 0.130
tube morphogenesis GO:0035239 95 0.129
tube development GO:0035295 125 0.126
cardiac cell fate determination GO:0060913 3 0.125
regulation of hormone levels GO:0010817 125 0.122
cellular amine metabolic process GO:0044106 41 0.122
post embryonic development GO:0009791 2 0.121
Worm
secretion GO:0046903 254 0.120
neuron development GO:0048666 113 0.116
Fly
negative regulation of cell death GO:0060548 345 0.116
regulation of secretion by cell GO:1903530 177 0.115
nerve development GO:0021675 4 0.113
specification of organ identity GO:0010092 3 0.113
limbic system development GO:0021761 3 0.112
glial cell migration GO:0008347 4 0.111
negative regulation of cell differentiation GO:0045596 171 0.110
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.110
behavior GO:0007610 112 0.110
tissue morphogenesis GO:0048729 96 0.107
neurogenesis GO:0022008 169 0.107
Fly
taxis GO:0042330 157 0.106
skeletal system development GO:0001501 79 0.105
cellular response to endogenous stimulus GO:0071495 336 0.104
head development GO:0060322 108 0.103
regulation of secretion GO:0051046 194 0.103
segmentation GO:0035282 4 0.100
forebrain regionalization GO:0021871 3 0.098
negative regulation of apoptotic process GO:0043066 316 0.098
regulation of cell development GO:0060284 161 0.098
chemotaxis GO:0006935 157 0.097
locomotory behavior GO:0007626 1 0.093
stem cell differentiation GO:0048863 93 0.086
metencephalon development GO:0022037 2 0.085
renal system development GO:0072001 63 0.085
Human
negative regulation of cell proliferation GO:0008285 228 0.084
neurological system process GO:0050877 163 0.084
enzyme linked receptor protein signaling pathway GO:0007167 303 0.084
morphogenesis of embryonic epithelium GO:0016331 4 0.083
regulation of anatomical structure morphogenesis GO:0022603 286 0.082
response to growth factor GO:0070848 205 0.082
positive regulation of tooth mineralization GO:0070172 2 0.082
cellular ketone metabolic process GO:0042180 80 0.082
embryonic camera type eye development GO:0031076 2 0.081
cell differentiation in spinal cord GO:0021515 1 0.080
neuron projection morphogenesis GO:0048812 50 0.080
Fly
somatic stem cell maintenance GO:0035019 4 0.078
regulation of neurogenesis GO:0050767 82 0.077
growth GO:0040007 202 0.077
positive regulation of transport GO:0051050 336 0.077
adult locomotory behavior GO:0008344 1 0.076
response to abiotic stimulus GO:0009628 336 0.075
cellular response to growth factor stimulus GO:0071363 197 0.074
embryonic forelimb morphogenesis GO:0035115 4 0.074
positive regulation of phosphorylation GO:0042327 394 0.073
vasculature development GO:0001944 181 0.073
negative regulation of programmed cell death GO:0043069 321 0.072
positive regulation of neural precursor cell proliferation GO:2000179 2 0.071
cardiac right ventricle morphogenesis GO:0003215 3 0.071
hormone secretion GO:0046879 65 0.071
embryonic organ morphogenesis GO:0048562 24 0.069
cell projection morphogenesis GO:0048858 129 0.069
Fly
regulation of cell cycle GO:0051726 393 0.067
pancreatic a cell differentiation GO:0003310 1 0.066
positive regulation of cell death GO:0010942 263 0.065
cellular response to oxygen containing compound GO:1901701 276 0.064
negative regulation of protein metabolic process GO:0051248 391 0.063
limb bud formation GO:0060174 1 0.062
neural tube patterning GO:0021532 2 0.061
kidney development GO:0001822 53 0.060
Human
endocrine system development GO:0035270 26 0.060
regulation of hormone secretion GO:0046883 57 0.060
negative regulation of cellular protein metabolic process GO:0032269 353 0.060
embryonic organ development GO:0048568 36 0.060
forebrain development GO:0030900 26 0.059
sensory organ morphogenesis GO:0090596 21 0.059
Fly
lipid metabolic process GO:0006629 381 0.058
stem cell development GO:0048864 69 0.057
peripheral nervous system development GO:0007422 2 0.057
mitotic cell cycle GO:0000278 326 0.057
regulation of stem cell differentiation GO:2000736 56 0.055
regulation of nervous system development GO:0051960 88 0.055
epithelial cell differentiation GO:0030855 141 0.054
cell part morphogenesis GO:0032990 137 0.053
Fly
neuroblast proliferation GO:0007405 4 0.053
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.053
cerebellum development GO:0021549 2 0.053
mitotic cell cycle process GO:1903047 286 0.052
blood vessel morphogenesis GO:0048514 162 0.052
chromatin organization GO:0006325 351 0.052
sensory organ development GO:0007423 52 0.051
globus pallidus development GO:0021759 1 0.051
positive regulation of cell motility GO:2000147 177 0.051
positive regulation of cell fate specification GO:0042660 2 0.051
outflow tract septum morphogenesis GO:0003148 4 0.050
cellular response to dna damage stimulus GO:0006974 379 0.050
positive regulation of apoptotic process GO:0043065 246 0.050
heart formation GO:0060914 2 0.050
ameboidal type cell migration GO:0001667 135 0.050
positive regulation of cellular component movement GO:0051272 181 0.049
regulation of response to external stimulus GO:0032101 222 0.049
regulation of kinase activity GO:0043549 314 0.049
regionalization GO:0003002 29 0.048
telencephalon development GO:0021537 17 0.048
positive regulation of cellular component organization GO:0051130 376 0.048
cytokine production GO:0001816 247 0.048
epithelial cell proliferation GO:0050673 128 0.048
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.048
regulation of neural precursor cell proliferation GO:2000177 4 0.047
response to lipid GO:0033993 206 0.047
pallium development GO:0021543 10 0.047
neural crest cell development GO:0014032 3 0.047
positive regulation of locomotion GO:0040017 186 0.046
cell proliferation in forebrain GO:0021846 1 0.046
negative regulation of cell development GO:0010721 48 0.046
embryonic epithelial tube formation GO:0001838 4 0.046
positive regulation of synaptic transmission GO:0050806 4 0.046
cellular response to hormone stimulus GO:0032870 125 0.045
regulation of growth GO:0040008 165 0.045
small gtpase mediated signal transduction GO:0007264 78 0.045
immune response GO:0006955 307 0.045
response to wounding GO:0009611 168 0.045
hormone transport GO:0009914 68 0.044
blood vessel development GO:0001568 172 0.044
regulation of protein localization GO:0032880 296 0.044
embryonic camera type eye morphogenesis GO:0048596 2 0.043
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.043
Fly
regulation of cytokine production GO:0001817 232 0.043
regulation of epithelial cell proliferation GO:0050678 113 0.043
regeneration GO:0031099 4 0.043
cartilage condensation GO:0001502 1 0.042
ras protein signal transduction GO:0007265 73 0.042
urogenital system development GO:0001655 65 0.042
Human
chemical homeostasis GO:0048878 306 0.042
multicellular organismal aging GO:0010259 3 0.041
sex determination GO:0007530 3 0.041
memory GO:0007613 3 0.041
signal release GO:0023061 70 0.041
regulation of male gonad development GO:2000018 4 0.040
embryo development GO:0009790 123 0.040
Worm
rostrocaudal neural tube patterning GO:0021903 1 0.040
motor neuron axon guidance GO:0008045 2 0.039
embryonic eye morphogenesis GO:0048048 2 0.039
female gamete generation GO:0007292 2 0.039
sensory perception GO:0007600 103 0.039
negative regulation of neurogenesis GO:0050768 26 0.039
defense response GO:0006952 315 0.039
cellular chemical homeostasis GO:0055082 180 0.039
cellular homeostasis GO:0019725 196 0.038
regulation of cell cycle process GO:0010564 266 0.038
positive regulation of programmed cell death GO:0043068 249 0.038
response to hormone GO:0009725 175 0.038
cytoplasmic transport GO:0016482 379 0.038
nitrogen compound transport GO:0071705 191 0.038
pattern specification process GO:0007389 43 0.038
negative regulation of phosphorus metabolic process GO:0010563 267 0.038
blastoderm segmentation GO:0007350 2 0.037
compound eye development GO:0048749 1 0.037
Fly
digestive system development GO:0055123 75 0.037
regulation of synaptic plasticity GO:0048167 3 0.037
anterior posterior axis specification GO:0009948 2 0.036
response to nitrogen compound GO:1901698 184 0.036
negative regulation of cellular component organization GO:0051129 235 0.036
cellular response to organonitrogen compound GO:0071417 124 0.036
metal ion transport GO:0030001 272 0.036
heart morphogenesis GO:0003007 48 0.036
positive regulation of secretion by cell GO:1903532 108 0.035
hippocampus development GO:0021766 1 0.035
response to external biotic stimulus GO:0043207 261 0.035
positive regulation of odontogenesis GO:0042482 3 0.035
synaptic transmission GO:0007268 61 0.035
response to biotic stimulus GO:0009607 276 0.034
cellular response to nitrogen compound GO:1901699 144 0.034
negative regulation of protein modification process GO:0031400 200 0.034
dermatome development GO:0061054 3 0.034
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.034
ossification GO:0001503 121 0.034
mesenchymal cell development GO:0014031 50 0.034
endothelial cell migration GO:0043542 86 0.034
ion homeostasis GO:0050801 230 0.034
tissue migration GO:0090130 119 0.034
digestive tract development GO:0048565 75 0.034
positive regulation of protein phosphorylation GO:0001934 313 0.033
pulmonary vein morphogenesis GO:0060577 1 0.033
endodermal cell fate commitment GO:0001711 4 0.033
inorganic ion transmembrane transport GO:0098660 231 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
response to organic cyclic compound GO:0014070 204 0.033
cell division GO:0051301 168 0.033
determination of adult lifespan GO:0008340 2 0.033
morphogenesis of an epithelium GO:0002009 60 0.033
muscle structure development GO:0061061 98 0.033
cell fate commitment GO:0045165 27 0.032
response to organonitrogen compound GO:0010243 156 0.032
epithelial cell migration GO:0010631 119 0.032
skin development GO:0043588 76 0.032
positive regulation of secretion GO:0051047 116 0.032
positive regulation of hydrolase activity GO:0051345 331 0.032
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.032
astrocyte differentiation GO:0048708 4 0.032
regulation of cell growth GO:0001558 135 0.031
epithelium migration GO:0090132 119 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.031
embryonic camera type eye formation GO:0060900 2 0.031
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.031
gabaergic neuron differentiation GO:0097154 1 0.031
protein localization to organelle GO:0033365 280 0.031
Human
chromatin modification GO:0016568 298 0.031
cell type specific apoptotic process GO:0097285 125 0.030
actin filament based process GO:0030029 224 0.030
cellular macromolecular complex assembly GO:0034622 324 0.030
positive regulation of cell migration GO:0030335 172 0.030
cell adhesion GO:0007155 325 0.030
positive regulation of epithelial cell proliferation GO:0050679 65 0.030
axonogenesis GO:0007409 31 0.030
cation transport GO:0006812 331 0.030
immune effector process GO:0002252 159 0.029
cell growth GO:0016049 160 0.029
neuromuscular junction development GO:0007528 3 0.029
nucleoside catabolic process GO:0009164 408 0.029
negative regulation of gliogenesis GO:0014014 3 0.029
cell fate commitment involved in pattern specification GO:0060581 1 0.029
cerebral cortex cell migration GO:0021795 3 0.029
ribonucleoside catabolic process GO:0042454 406 0.029
ventral spinal cord development GO:0021517 1 0.029
biological adhesion GO:0022610 331 0.029
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.029
peptide transport GO:0015833 74 0.029
amide transport GO:0042886 76 0.028
negative regulation of cell cycle GO:0045786 193 0.028
positive regulation of hormone biosynthetic process GO:0046886 4 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
regulation of protein kinase activity GO:0045859 289 0.028
apoptotic signaling pathway GO:0097190 268 0.028
mesenchyme development GO:0060485 59 0.028
ventral spinal cord interneuron differentiation GO:0021514 1 0.028
regulation of cardioblast differentiation GO:0051890 4 0.028
mesonephric duct development GO:0072177 3 0.028
regulation of protein transport GO:0051223 213 0.028
oogenesis GO:0048477 2 0.028
regulation of wnt signaling pathway GO:0030111 123 0.028
positive regulation of aldosterone metabolic process GO:0032346 2 0.028
cation transmembrane transport GO:0098655 238 0.028
regulation of proteolysis GO:0030162 293 0.027
cellular lipid metabolic process GO:0044255 303 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
salivary gland morphogenesis GO:0007435 4 0.027
positive regulation of cardioblast differentiation GO:0051891 2 0.027
negative regulation of transport GO:0051051 176 0.027
inner ear development GO:0048839 8 0.027
mesenchymal cell differentiation GO:0048762 52 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
endodermal cell fate specification GO:0001714 4 0.027
positive regulation of nervous system development GO:0051962 54 0.027
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.026
regulation of ion transport GO:0043269 189 0.026
response to other organism GO:0051707 261 0.026
regulation of mitotic cell cycle GO:0007346 189 0.026
regulation of cellular response to stress GO:0080135 244 0.026
follicle stimulating hormone secretion GO:0046884 3 0.026
osteoblast differentiation GO:0001649 92 0.026
paramesonephric duct development GO:0061205 2 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
regulation of system process GO:0044057 101 0.026
positive regulation of cell cycle GO:0045787 140 0.026
central nervous system neuron differentiation GO:0021953 9 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
positive regulation of cytokine production GO:0001819 167 0.026
cellular response to acid chemical GO:0071229 44 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
gland development GO:0048732 48 0.026
transmembrane transport GO:0055085 399 0.025
positive regulation of cell development GO:0010720 92 0.025
angiogenesis GO:0001525 147 0.025
inorganic cation transmembrane transport GO:0098662 194 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
eye photoreceptor cell differentiation GO:0001754 2 0.025
Fly
brain morphogenesis GO:0048854 1 0.025
immune system development GO:0002520 195 0.025
regulation of cell projection organization GO:0031344 107 0.025
negative regulation of cell migration GO:0030336 102 0.025
reproductive process GO:0022414 106 0.025
striated muscle tissue development GO:0014706 59 0.025
hematopoietic or lymphoid organ development GO:0048534 186 0.025
oxidation reduction process GO:0055114 396 0.025
regulation of transferase activity GO:0051338 355 0.025
somitogenesis GO:0001756 2 0.025
single organism cellular localization GO:1902580 332 0.025
muscle system process GO:0003012 81 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
wnt signaling pathway GO:0016055 156 0.024
regulation of cell morphogenesis GO:0022604 153 0.024
negative regulation of neuron differentiation GO:0045665 21 0.024
peptide secretion GO:0002790 51 0.024
epithelial tube morphogenesis GO:0060562 38 0.024
negative regulation of growth GO:0045926 97 0.024
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.024
protein ubiquitination GO:0016567 314 0.024
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
forebrain neuron development GO:0021884 2 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
protein maturation GO:0051604 233 0.023
cell activation GO:0001775 213 0.023
response to radiation GO:0009314 151 0.023
chordate embryonic development GO:0043009 34 0.023
mapk cascade GO:0000165 288 0.023
eye development GO:0001654 42 0.023
vesicle mediated transport GO:0016192 371 0.023
response to axon injury GO:0048678 1 0.023
regulation of peptide hormone secretion GO:0090276 41 0.023
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 1 0.023
regulation of odontogenesis GO:0042481 4 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
microtubule cytoskeleton organization GO:0000226 176 0.023
heart development GO:0007507 95 0.023
regulation of binding GO:0051098 111 0.023
regulation of intracellular transport GO:0032386 195 0.023
response to acid chemical GO:0001101 66 0.023
photoreceptor cell differentiation GO:0046530 2 0.023
Fly
formation of primary germ layer GO:0001704 42 0.022
nucleotide catabolic process GO:0009166 408 0.022
multicellular organismal response to stress GO:0033555 1 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
protein catabolic process GO:0030163 325 0.022
negative regulation of locomotion GO:0040013 118 0.022
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.022
muscle tissue development GO:0060537 62 0.022
detection of stimulus GO:0051606 85 0.022
positive regulation of neurogenesis GO:0050769 49 0.022
peptide hormone secretion GO:0030072 50 0.022
cellular response to lipid GO:0071396 127 0.022
protein localization to nucleus GO:0034504 136 0.022
Human
hair follicle morphogenesis GO:0031069 2 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
purine containing compound catabolic process GO:0072523 411 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
ion transmembrane transport GO:0034220 338 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
luteinizing hormone secretion GO:0032275 1 0.022
optic nerve development GO:0021554 2 0.022
regulation of neuroblast proliferation GO:1902692 3 0.022
regulation of neuron projection development GO:0010975 57 0.022
regulation of peptidase activity GO:0052547 180 0.022
visual behavior GO:0007632 2 0.022
circadian behavior GO:0048512 2 0.022
cellular response to organic cyclic compound GO:0071407 127 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
axon development GO:0061564 34 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
positive regulation of mapk cascade GO:0043410 190 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
neural tube formation GO:0001841 3 0.022
multicellular organismal signaling GO:0035637 34 0.021
protein modification by small protein conjugation GO:0032446 342 0.021
spinal cord dorsal ventral patterning GO:0021513 2 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.021
g protein coupled receptor signaling pathway GO:0007186 207 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
positive regulation of catabolic process GO:0009896 310 0.021
adenylate cyclase inhibiting adrenergic receptor signaling pathway GO:0071881 1 0.021
guanosine containing compound metabolic process GO:1901068 244 0.021
neurotransmitter secretion GO:0007269 4 0.021
muscle organ development GO:0007517 56 0.021
microtubule based process GO:0007017 210 0.021
regulation of cardiac muscle cell proliferation GO:0060043 4 0.021
regulation of epithelial cell migration GO:0010632 93 0.021
retinal ganglion cell axon guidance GO:0031290 2 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
regulation of immune response GO:0050776 201 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
sensory perception of sound GO:0007605 37 0.021
cellular response to prostaglandin stimulus GO:0071379 4 0.020
regulation of canonical wnt signaling pathway GO:0060828 88 0.020
negative regulation of cell growth GO:0030308 83 0.020
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
cellular ion homeostasis GO:0006873 168 0.020
gtp metabolic process GO:0046039 239 0.020
associative learning GO:0008306 1 0.020
regulation of dna metabolic process GO:0051052 153 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
ear development GO:0043583 14 0.020
histone modification GO:0016570 251 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
covalent chromatin modification GO:0016569 254 0.020
cell cycle phase transition GO:0044770 173 0.020
negative regulation of kidney development GO:0090185 2 0.020
positive regulation of neuroblast proliferation GO:0002052 2 0.020
rhythmic behavior GO:0007622 2 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
intracellular protein transport GO:0006886 270 0.019
regulation of heart growth GO:0060420 4 0.019
ear morphogenesis GO:0042471 7 0.019
oxidative stress induced premature senescence GO:0090403 3 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
epidermis development GO:0008544 59 0.019
sensory perception of light stimulus GO:0050953 35 0.019
muscle contraction GO:0006936 73 0.019
positive regulation of immune system process GO:0002684 283 0.019
neuron projection regeneration GO:0031102 1 0.019
neural crest cell migration GO:0001755 2 0.019
innate immune response GO:0045087 178 0.019
drinking behavior GO:0042756 1 0.019
protein processing GO:0016485 226 0.019
cytosolic calcium ion homeostasis GO:0051480 89 0.019
neuroendocrine cell differentiation GO:0061101 2 0.019
regulation of peptide transport GO:0090087 62 0.019
negative regulation of synaptic transmission GO:0050805 2 0.019
lens development in camera type eye GO:0002088 2 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
regulation of cell adhesion GO:0030155 166 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
nuclear transport GO:0051169 179 0.019
regulation of immune effector process GO:0002697 91 0.018
negative regulation of protein processing GO:0010955 142 0.018
regulation of mapk cascade GO:0043408 262 0.018
post embryonic organ development GO:0048569 1 0.018
embryonic viscerocranium morphogenesis GO:0048703 1 0.018
mating GO:0007618 1 0.018
thymus development GO:0048538 3 0.018
purine nucleotide catabolic process GO:0006195 405 0.018

SIX3 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.065
Human
nervous system disease DOID:863 431 0.065
Human
disease of metabolism DOID:0014667 295 0.049
cancer DOID:162 167 0.039
disease of cellular proliferation DOID:14566 174 0.039
musculoskeletal system disease DOID:17 223 0.036
eye and adnexa disease DOID:1492 150 0.033
eye disease DOID:5614 149 0.033
organ system cancer DOID:0050686 164 0.031
central nervous system disease DOID:331 186 0.025
connective tissue disease DOID:65 109 0.025
bone disease DOID:0080001 88 0.025