Homo sapiens

0 known processes

SIX6

SIX homeobox 6

(Aliases: MCOPCT2,OPTX2,Six9)

SIX6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ morphogenesis GO:0009887 147 0.821
Zebrafish Fly
cranial nerve development GO:0021545 4 0.723
organ formation GO:0048645 3 0.714
regulation of cell differentiation GO:0045595 393 0.702
anatomical structure formation involved in morphogenesis GO:0048646 284 0.597
epithelium development GO:0060429 227 0.559
regulation of locomotion GO:0040012 329 0.557
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.552
negative regulation of multicellular organismal process GO:0051241 317 0.511
neuron fate commitment GO:0048663 2 0.505
system process GO:0003008 349 0.494
hindbrain development GO:0030902 3 0.467
cell cell signaling GO:0007267 155 0.454
negative regulation of developmental process GO:0051093 247 0.423
circulatory system development GO:0072359 262 0.423
cardiovascular system development GO:0072358 262 0.420
cardiac right ventricle morphogenesis GO:0003215 3 0.401
cell development GO:0048468 328 0.387
Fly
locomotory behavior GO:0007626 1 0.381
nervous system development GO:0007399 293 0.371
Human Fly
g protein coupled receptor signaling pathway GO:0007186 207 0.361
positive regulation of developmental process GO:0051094 314 0.356
embryonic morphogenesis GO:0048598 85 0.334
regulation of cellular component movement GO:0051270 334 0.320
skeletal system development GO:0001501 79 0.320
neuron differentiation GO:0030182 138 0.309
Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.303
regulation of cellular ketone metabolic process GO:0010565 50 0.300
forebrain regionalization GO:0021871 3 0.294
Human
specification of organ identity GO:0010092 3 0.288
extraocular skeletal muscle development GO:0002074 1 0.275
regulation of cell motility GO:2000145 299 0.262
nerve development GO:0021675 4 0.236
stem cell differentiation GO:0048863 93 0.233
head development GO:0060322 108 0.228
Human
response to abiotic stimulus GO:0009628 336 0.225
positive regulation of cell differentiation GO:0045597 211 0.222
tissue morphogenesis GO:0048729 96 0.214
negative regulation of cell death GO:0060548 345 0.213
central nervous system development GO:0007417 123 0.208
Human
brain development GO:0007420 97 0.206
Human
negative regulation of cell differentiation GO:0045596 171 0.202
amine metabolic process GO:0009308 44 0.201
cardiac cell fate determination GO:0060913 3 0.200
stem cell development GO:0048864 69 0.197
hematopoietic or lymphoid organ development GO:0048534 186 0.196
regulation of cell development GO:0060284 161 0.196
behavior GO:0007610 112 0.191
positive regulation of cell proliferation GO:0008284 301 0.191
neurogenesis GO:0022008 169 0.188
Fly
immune system development GO:0002520 195 0.185
secretion by cell GO:0032940 226 0.178
heart formation GO:0060914 2 0.174
cell morphogenesis GO:0000902 296 0.173
Fly
generation of neurons GO:0048699 152 0.172
Fly
metencephalon development GO:0022037 2 0.166
forebrain generation of neurons GO:0021872 3 0.165
vasculature development GO:0001944 181 0.156
cellular ketone metabolic process GO:0042180 80 0.153
regulation of cellular amino acid metabolic process GO:0006521 6 0.148
regulation of cell migration GO:0030334 289 0.147
menstrual cycle phase GO:0022601 2 0.146
ion transmembrane transport GO:0034220 338 0.139
cellular component morphogenesis GO:0032989 314 0.134
Fly
lipid metabolic process GO:0006629 381 0.133
transmembrane transport GO:0055085 399 0.132
metal ion transport GO:0030001 272 0.128
cell fate determination GO:0001709 3 0.127
epithelial cell differentiation GO:0030855 141 0.123
mesenchymal cell development GO:0014031 50 0.122
ion homeostasis GO:0050801 230 0.122
regulation of cellular amine metabolic process GO:0033238 11 0.121
cation transport GO:0006812 331 0.119
neurological system process GO:0050877 163 0.117
regulation of stem cell differentiation GO:2000736 56 0.117
inorganic cation transmembrane transport GO:0098662 194 0.115
response to oxygen containing compound GO:1901700 369 0.114
negative regulation of programmed cell death GO:0043069 321 0.114
cell morphogenesis involved in differentiation GO:0000904 144 0.114
Fly
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.113
glycine import GO:0036233 1 0.113
cation transmembrane transport GO:0098655 238 0.113
chemical homeostasis GO:0048878 306 0.111
heart development GO:0007507 95 0.110
tube development GO:0035295 125 0.109
sensory organ development GO:0007423 52 0.109
Human Zebrafish Fly
blood vessel development GO:0001568 172 0.108
regulation of hormone levels GO:0010817 125 0.108
cerebellum development GO:0021549 2 0.106
positive regulation of cellular amine metabolic process GO:0033240 7 0.106
morphogenesis of an epithelium GO:0002009 60 0.106
synaptic transmission glycinergic GO:0060012 1 0.105
heart morphogenesis GO:0003007 48 0.104
positive regulation of phosphorylation GO:0042327 394 0.104
regulation of cell cycle GO:0051726 393 0.103
forebrain development GO:0030900 26 0.103
Human
negative regulation of apoptotic process GO:0043066 316 0.100
positive regulation of transport GO:0051050 336 0.100
endocrine system development GO:0035270 26 0.100
cell differentiation in spinal cord GO:0021515 1 0.100
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.099
cellular response to endogenous stimulus GO:0071495 336 0.099
neuron development GO:0048666 113 0.099
Fly
post embryonic development GO:0009791 2 0.098
Worm
limbic system development GO:0021761 3 0.098
morphogenesis of embryonic epithelium GO:0016331 4 0.096
secretion GO:0046903 254 0.095
response to hormone GO:0009725 175 0.094
cell fate commitment GO:0045165 27 0.091
sensory perception GO:0007600 103 0.091
mesenchyme development GO:0060485 59 0.091
regulation of body fluid levels GO:0050878 99 0.088
response to wounding GO:0009611 168 0.087
regulation of secretion GO:0051046 194 0.087
inorganic ion transmembrane transport GO:0098660 231 0.085
gland development GO:0048732 48 0.085
positive regulation of cell cycle GO:0045787 140 0.084
positive regulation of locomotion GO:0040017 186 0.083
neuron projection development GO:0031175 106 0.080
Fly
cardiac chamber development GO:0003205 30 0.079
cell projection organization GO:0030030 252 0.079
Fly
embryonic camera type eye formation GO:0060900 2 0.078
regulation of response to external stimulus GO:0032101 222 0.078
muscle structure development GO:0061061 98 0.078
cellular amine metabolic process GO:0044106 41 0.076
cellular homeostasis GO:0019725 196 0.076
mating GO:0007618 1 0.075
response to lipid GO:0033993 206 0.075
cellular amino acid metabolic process GO:0006520 116 0.075
detection of stimulus GO:0051606 85 0.074
organic hydroxy compound metabolic process GO:1901615 147 0.074
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.073
spinal cord development GO:0021510 4 0.073
taxis GO:0042330 157 0.072
blood vessel morphogenesis GO:0048514 162 0.071
cellular lipid metabolic process GO:0044255 303 0.069
cardiac ventricle formation GO:0003211 2 0.069
cellular ion homeostasis GO:0006873 168 0.069
cell activation GO:0001775 213 0.066
embryonic organ development GO:0048568 36 0.066
regulation of ion transport GO:0043269 189 0.066
thymus development GO:0048538 3 0.066
pattern specification process GO:0007389 43 0.065
Human
digestive system development GO:0055123 75 0.065
signal transduction by phosphorylation GO:0023014 297 0.064
metal ion homeostasis GO:0055065 169 0.064
eye development GO:0001654 42 0.064
Human Zebrafish Fly
positive regulation of cell development GO:0010720 92 0.064
regulation of secretion by cell GO:1903530 177 0.063
mesenchymal cell differentiation GO:0048762 52 0.063
glial cell migration GO:0008347 4 0.062
positive regulation of cellular component organization GO:0051130 376 0.062
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.062
cardiac muscle tissue development GO:0048738 39 0.062
cytoplasmic transport GO:0016482 379 0.062
skeletal system morphogenesis GO:0048705 24 0.062
peripheral nervous system development GO:0007422 2 0.061
aortic valve development GO:0003176 3 0.061
nitrogen compound transport GO:0071705 191 0.060
embryo development GO:0009790 123 0.060
Worm
skin development GO:0043588 76 0.060
negative regulation of cellular protein metabolic process GO:0032269 353 0.059
chemotaxis GO:0006935 157 0.059
wound healing GO:0042060 115 0.059
ameboidal type cell migration GO:0001667 135 0.059
regulation of nervous system development GO:0051960 88 0.058
trophectodermal cell differentiation GO:0001829 3 0.058
response to organic cyclic compound GO:0014070 204 0.058
striated muscle tissue development GO:0014706 59 0.058
positive regulation of cell death GO:0010942 263 0.058
carbohydrate derivative biosynthetic process GO:1901137 207 0.058
enzyme linked receptor protein signaling pathway GO:0007167 303 0.056
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.056
chromatin modification GO:0016568 298 0.056
growth GO:0040007 202 0.056
chromatin organization GO:0006325 351 0.056
positive regulation of programmed cell death GO:0043068 249 0.056
epidermis development GO:0008544 59 0.055
covalent chromatin modification GO:0016569 254 0.054
adult locomotory behavior GO:0008344 1 0.054
actin filament based process GO:0030029 224 0.053
positive regulation of apoptotic process GO:0043065 246 0.053
mapk cascade GO:0000165 288 0.053
memory GO:0007613 3 0.052
negative regulation of protein metabolic process GO:0051248 391 0.052
muscle organ development GO:0007517 56 0.052
tube morphogenesis GO:0035239 95 0.052
camera type eye development GO:0043010 25 0.052
Zebrafish
inner ear morphogenesis GO:0042472 4 0.051
cellular metal ion homeostasis GO:0006875 146 0.051
optic nerve development GO:0021554 2 0.051
multicellular organismal response to stress GO:0033555 1 0.051
negative regulation of cellular component organization GO:0051129 235 0.050
positive regulation of immune system process GO:0002684 283 0.050
histone modification GO:0016570 251 0.050
bmp signaling pathway involved in heart development GO:0061312 3 0.049
sensory organ morphogenesis GO:0090596 21 0.049
Zebrafish Fly
hormone secretion GO:0046879 65 0.049
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.049
angiogenesis GO:0001525 147 0.049
muscle tissue development GO:0060537 62 0.049
regulation of neurogenesis GO:0050767 82 0.049
segmentation GO:0035282 4 0.049
glycine transport GO:0015816 3 0.048
regulation of transferase activity GO:0051338 355 0.048
cell adhesion GO:0007155 325 0.048
hemopoiesis GO:0030097 180 0.048
cell projection morphogenesis GO:0048858 129 0.048
Fly
cellular cation homeostasis GO:0030003 163 0.047
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.047
regulation of cell morphogenesis GO:0022604 153 0.047
regionalization GO:0003002 29 0.047
Human
divalent inorganic cation homeostasis GO:0072507 136 0.046
cellular chemical homeostasis GO:0055082 180 0.046
alcohol metabolic process GO:0006066 114 0.046
signal release GO:0023061 70 0.046
positive regulation of protein phosphorylation GO:0001934 313 0.046
epithelial to mesenchymal transition GO:0001837 48 0.046
positive regulation of lipid metabolic process GO:0045834 50 0.046
anion transport GO:0006820 161 0.045
epithelial cell proliferation GO:0050673 128 0.045
embryonic camera type eye development GO:0031076 2 0.045
regulation of mapk cascade GO:0043408 262 0.045
regulation of lipid metabolic process GO:0019216 96 0.045
cardiac left ventricle formation GO:0003218 1 0.045
cell part morphogenesis GO:0032990 137 0.044
Fly
regulation of methylation dependent chromatin silencing GO:0090308 3 0.044
forebrain neuron differentiation GO:0021879 3 0.044
leukocyte activation GO:0045321 164 0.043
leukocyte differentiation GO:0002521 98 0.043
regulation of protein localization GO:0032880 296 0.043
oxidation reduction process GO:0055114 396 0.043
organophosphate catabolic process GO:0046434 430 0.043
monovalent inorganic cation transport GO:0015672 128 0.043
response to external biotic stimulus GO:0043207 261 0.043
myeloid cell differentiation GO:0030099 117 0.042
positive regulation of cellular component movement GO:0051272 181 0.042
cellular response to dna damage stimulus GO:0006974 379 0.042
regulation of protein transport GO:0051223 213 0.042
synaptic transmission GO:0007268 61 0.042
ribonucleotide catabolic process GO:0009261 405 0.042
defense response GO:0006952 315 0.042
forebrain dorsal ventral pattern formation GO:0021798 1 0.041
Human
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.041
positive regulation of neural precursor cell proliferation GO:2000179 2 0.041
epidermis morphogenesis GO:0048730 3 0.041
positive regulation of cardioblast differentiation GO:0051891 2 0.041
negative regulation of cell motility GO:2000146 104 0.040
myeloid leukocyte differentiation GO:0002573 60 0.040
cardiac chamber formation GO:0003207 2 0.040
organonitrogen compound biosynthetic process GO:1901566 200 0.040
positive regulation of cell motility GO:2000147 177 0.040
cellular response to hormone stimulus GO:0032870 125 0.040
response to cytokine GO:0034097 232 0.040
regulation of growth GO:0040008 165 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.039
Fly
regulation of cellular response to stress GO:0080135 244 0.039
regulation of neuron differentiation GO:0045664 70 0.039
renal system development GO:0072001 63 0.039
Human
response to decreased oxygen levels GO:0036293 96 0.039
amide transport GO:0042886 76 0.039
calcium ion transport GO:0006816 147 0.039
negative regulation of phosphate metabolic process GO:0045936 267 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
positive regulation of cell division GO:0051781 59 0.038
regulation of reactive oxygen species metabolic process GO:2000377 41 0.038
cellular response to growth factor stimulus GO:0071363 197 0.038
embryonic camera type eye morphogenesis GO:0048596 2 0.038
regulation of myeloid cell differentiation GO:0045637 81 0.037
cytokine production GO:0001816 247 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.037
embryonic epithelial tube formation GO:0001838 4 0.037
response to steroid hormone GO:0048545 80 0.037
divalent metal ion transport GO:0070838 152 0.037
cardiac right ventricle formation GO:0003219 1 0.037
nucleoside catabolic process GO:0009164 408 0.037
cytosolic calcium ion homeostasis GO:0051480 89 0.037
heart field specification GO:0003128 2 0.036
sensory perception of light stimulus GO:0050953 35 0.036
somatic stem cell maintenance GO:0035019 4 0.036
embryonic eye morphogenesis GO:0048048 2 0.036
immune response GO:0006955 307 0.036
blastocyst development GO:0001824 3 0.036
urogenital system development GO:0001655 65 0.036
Human
kidney development GO:0001822 53 0.036
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
negative regulation of locomotion GO:0040013 118 0.036
nucleoside triphosphate catabolic process GO:0009143 394 0.036
serotonin transport GO:0006837 3 0.036
negative regulation of cell migration GO:0030336 102 0.035
peptide transport GO:0015833 74 0.035
neural crest cell development GO:0014032 3 0.035
regulation of response to dna damage stimulus GO:2001020 94 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
reproductive process GO:0022414 106 0.035
regulation of epithelial cell proliferation GO:0050678 113 0.034
sodium ion transmembrane transport GO:0035725 59 0.034
positive regulation of transferase activity GO:0051347 227 0.034
response to radiation GO:0009314 151 0.034
multicellular organismal aging GO:0010259 3 0.034
response to estrogen GO:0043627 47 0.034
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.034
second messenger mediated signaling GO:0019932 78 0.034
response to other organism GO:0051707 261 0.034
blood circulation GO:0008015 113 0.033
positive regulation of synaptic transmission GO:0050806 4 0.033
hormone transport GO:0009914 68 0.033
negative regulation of cell development GO:0010721 48 0.033
divalent inorganic cation transport GO:0072511 158 0.033
positive regulation of mapk cascade GO:0043410 190 0.033
regulation of cell division GO:0051302 116 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.032
activation of protein kinase activity GO:0032147 90 0.032
positive regulation of hydrolase activity GO:0051345 331 0.032
cyclic nucleotide metabolic process GO:0009187 82 0.032
steroid metabolic process GO:0008202 94 0.032
forelimb morphogenesis GO:0035136 4 0.032
ribonucleoside catabolic process GO:0042454 406 0.032
negative regulation of cell proliferation GO:0008285 228 0.032
cellular divalent inorganic cation homeostasis GO:0072503 128 0.032
response to hypoxia GO:0001666 96 0.032
regulation of vasculature development GO:1901342 97 0.032
cellular response to oxygen containing compound GO:1901701 276 0.032
response to organonitrogen compound GO:0010243 156 0.032
aortic valve morphogenesis GO:0003180 3 0.032
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
epithelium migration GO:0090132 119 0.031
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
biological adhesion GO:0022610 331 0.031
positive regulation of epithelial cell proliferation GO:0050679 65 0.031
wnt signaling pathway GO:0016055 156 0.031
positive regulation of cytokine production GO:0001819 167 0.031
regulation of kinase activity GO:0043549 314 0.031
response to oxygen levels GO:0070482 100 0.031
embryonic skeletal system development GO:0048706 13 0.031
cell division GO:0051301 168 0.031
regulation of protein kinase activity GO:0045859 289 0.031
small gtpase mediated signal transduction GO:0007264 78 0.030
embryonic forelimb morphogenesis GO:0035115 4 0.030
lipid catabolic process GO:0016042 84 0.030
pituitary gland development GO:0021983 2 0.030
mitotic cell cycle GO:0000278 326 0.030
regulation of behavior GO:0050795 82 0.030
protein localization to organelle GO:0033365 280 0.030
Human
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.030
regulation of neural precursor cell proliferation GO:2000177 4 0.030
regulation of organ formation GO:0003156 4 0.029
cardiac muscle cell contraction GO:0086003 4 0.029
hair follicle morphogenesis GO:0031069 2 0.029
regulation of binding GO:0051098 111 0.029
embryonic organ morphogenesis GO:0048562 24 0.029
globus pallidus development GO:0021759 1 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
peptide secretion GO:0002790 51 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.029
negative regulation of transport GO:0051051 176 0.029
single organism cellular localization GO:1902580 332 0.029
digestive tract development GO:0048565 75 0.029
regulation of cytokine production GO:0001817 232 0.029
potassium ion transport GO:0006813 62 0.029
regeneration GO:0031099 4 0.029
protein processing GO:0016485 226 0.029
blastocyst formation GO:0001825 3 0.029
regulation of epithelial to mesenchymal transition GO:0010717 37 0.029
epithelial tube morphogenesis GO:0060562 38 0.029
regulation of synaptic plasticity GO:0048167 3 0.029
photoreceptor cell differentiation GO:0046530 2 0.029
Fly
cellular response to cytokine stimulus GO:0071345 181 0.029
cell type specific apoptotic process GO:0097285 125 0.029
regulation of cellular component biogenesis GO:0044087 281 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
response to virus GO:0009615 126 0.028
negative regulation of immune system process GO:0002683 136 0.028
cell proliferation involved in heart valve development GO:2000793 1 0.028
negative regulation of cellular component movement GO:0051271 106 0.028
positive regulation of protein kinase activity GO:0045860 190 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
positive regulation of catabolic process GO:0009896 310 0.028
response to growth factor GO:0070848 205 0.028
purine containing compound catabolic process GO:0072523 411 0.028
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 4 0.028
regulation of transmembrane transport GO:0034762 139 0.028
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.028
regulation of metal ion transport GO:0010959 120 0.027
response to inorganic substance GO:0010035 127 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
chordate embryonic development GO:0043009 34 0.027
reactive oxygen species metabolic process GO:0072593 75 0.027
lung alveolus development GO:0048286 4 0.026
apoptotic signaling pathway GO:0097190 268 0.026
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.026
regulation of proteolysis GO:0030162 293 0.026
cation homeostasis GO:0055080 189 0.026
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
regulation of dna metabolic process GO:0051052 153 0.025
cardiocyte differentiation GO:0035051 23 0.025
regulation of heart morphogenesis GO:2000826 4 0.025
epithelial cell migration GO:0010631 119 0.025
associative learning GO:0008306 1 0.025
lymphocyte activation GO:0046649 133 0.025
cellular response to organic cyclic compound GO:0071407 127 0.025
blood vessel maturation GO:0001955 1 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
determination of adult lifespan GO:0008340 2 0.025
positive regulation of nervous system development GO:0051962 54 0.025
organic anion transport GO:0015711 103 0.025
actin filament based movement GO:0030048 17 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.025
central nervous system neuron differentiation GO:0021953 9 0.025
calcium ion homeostasis GO:0055074 122 0.025
nucleoside triphosphate metabolic process GO:0009141 422 0.025
positive regulation of kinase activity GO:0033674 204 0.025
regulation of angiogenesis GO:0045765 92 0.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.024
ras protein signal transduction GO:0007265 73 0.024
basophil differentiation GO:0030221 2 0.024
cell growth GO:0016049 160 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
regulation of protein complex assembly GO:0043254 147 0.024
regulation of cell cycle process GO:0010564 266 0.024
monocarboxylic acid metabolic process GO:0032787 185 0.024
regulation of ossification GO:0030278 58 0.024
response to light stimulus GO:0009416 87 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.024
copulation GO:0007620 1 0.024
positive regulation of protein transport GO:0051222 135 0.024
sequestering of metal ion GO:0051238 24 0.024
neuromuscular junction development GO:0007528 3 0.024
purine containing compound biosynthetic process GO:0072522 88 0.024
negative regulation of protein modification process GO:0031400 200 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
response to alcohol GO:0097305 64 0.024
l amino acid import GO:0043092 4 0.024
tissue migration GO:0090130 119 0.024
female gamete generation GO:0007292 2 0.024
negative regulation of cell cycle GO:0045786 193 0.023
developmental programmed cell death GO:0010623 3 0.023
neuron projection morphogenesis GO:0048812 50 0.023
Fly
immune effector process GO:0002252 159 0.023
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.023
erk1 and erk2 cascade GO:0070371 104 0.023
protein maturation GO:0051604 233 0.023
dna repair GO:0006281 198 0.023
cellular response to nitrogen compound GO:1901699 144 0.023
neuroblast proliferation GO:0007405 4 0.023
nucleotide catabolic process GO:0009166 408 0.023
detection of stimulus involved in sensory perception GO:0050906 43 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
lipid biosynthetic process GO:0008610 177 0.023
rhythmic behavior GO:0007622 2 0.023
vesicle mediated transport GO:0016192 371 0.023
connective tissue development GO:0061448 39 0.023
soft palate development GO:0060023 3 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.022
innate immune response GO:0045087 178 0.022
positive regulation of organelle organization GO:0010638 195 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
compound eye development GO:0048749 1 0.022
Zebrafish Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
motor neuron axon guidance GO:0008045 2 0.022
membrane organization GO:0061024 292 0.022
regulation of endopeptidase activity GO:0052548 170 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
regulation of system process GO:0044057 101 0.022
regulation of biomineral tissue development GO:0070167 31 0.022
hematopoietic progenitor cell differentiation GO:0002244 38 0.022
purine nucleoside monophosphate catabolic process GO:0009128 158 0.022
oogenesis GO:0048477 2 0.022
negative regulation of protein maturation GO:1903318 142 0.022
regulation of peptidase activity GO:0052547 180 0.022
leukocyte migration GO:0050900 107 0.022
nucleocytoplasmic transport GO:0006913 176 0.022
regulation of mitotic cell cycle GO:0007346 189 0.022
cellular response to hypoxia GO:0071456 51 0.022
positive regulation of neurogenesis GO:0050769 49 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.022
blastoderm segmentation GO:0007350 2 0.022
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
outflow tract septum morphogenesis GO:0003148 4 0.022
post embryonic organ development GO:0048569 1 0.022
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 1 0.021
regulation of intracellular transport GO:0032386 195 0.021

SIX6 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.151
Human
nervous system disease DOID:863 431 0.151
Human
eye and adnexa disease DOID:1492 150 0.090
eye disease DOID:5614 149 0.077
retinal disease DOID:5679 118 0.065
musculoskeletal system disease DOID:17 223 0.026
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023