|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
1.000
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.999
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.999
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.999
|
|
|
|
negative regulation of androgen receptor activity
|
GO:2000824 |
2 |
0.997
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.996
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.996
|
Human |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.995
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.993
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.993
|
|
|
|
heart valve formation
|
GO:0003188 |
2 |
0.992
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.990
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.989
|
Human |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.987
|
Human |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.985
|
Human |
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.979
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.977
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.972
|
|
|
|
response to host defenses
|
GO:0052200 |
2 |
0.970
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.963
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.961
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.959
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.958
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.954
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.953
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.948
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.940
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.936
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.930
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.929
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.928
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.922
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.916
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.914
|
Human |
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.911
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.906
|
|
|
|
atrioventricular valve formation
|
GO:0003190 |
1 |
0.902
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.897
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.894
|
|
|
|
evasion or tolerance of host defenses by virus
|
GO:0019049 |
2 |
0.887
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.883
|
Human |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.882
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
2 |
0.878
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.874
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.872
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.866
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.863
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.851
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.847
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.839
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.839
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.830
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.829
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.818
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.810
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.805
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.795
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.787
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.786
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.784
|
Human Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.781
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.779
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.779
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.758
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.756
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.751
|
Mouse |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.747
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.736
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.735
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.730
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.712
|
Human |
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.700
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.693
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.693
|
Human |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.691
|
|
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
0.684
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.681
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.677
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.671
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.666
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.665
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.662
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
0.653
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.643
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.642
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.642
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.641
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.638
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.632
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.632
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.631
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.631
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.626
|
|
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.625
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.624
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.622
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.610
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
10 |
0.609
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.609
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.606
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.605
|
Human |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.603
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.601
|
|
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
0.600
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.594
|
Mouse |
|
|
avoidance of defenses of other organism involved in symbiotic interaction
|
GO:0051832 |
2 |
0.589
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.585
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.583
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.582
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.576
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.575
|
|
|
|
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900224 |
1 |
0.574
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.572
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.564
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.562
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.561
|
Human |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.553
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.551
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.549
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.548
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.543
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.537
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.536
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.528
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.520
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.518
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.517
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.517
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.506
|
|
|
|
growth
|
GO:0040007 |
202 |
0.506
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.505
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.502
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.502
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.498
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.486
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.484
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.481
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.481
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.475
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
1 |
0.471
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.471
|
|
|
|
intracellular bile acid receptor signaling pathway
|
GO:0038185 |
1 |
0.470
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.466
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.463
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.460
|
|
|
|
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072361 |
2 |
0.457
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.449
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.448
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.447
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.441
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.439
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.427
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.422
|
Mouse |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.416
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.416
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.415
|
|
|
|
regulation of transcription regulatory region dna binding
|
GO:2000677 |
15 |
0.415
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.412
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.412
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.411
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.410
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.406
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.401
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.400
|
|
|
|
evasion or tolerance of defenses of other organism involved in symbiotic interaction
|
GO:0051834 |
2 |
0.397
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.397
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.390
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.383
|
Mouse |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.374
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.369
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.367
|
|
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.366
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.365
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.364
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.364
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.360
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.352
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.350
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry
|
GO:1900094 |
1 |
0.350
|
|
|
|
regulation of nodal signaling pathway
|
GO:1900107 |
1 |
0.349
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.348
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.343
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.342
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.339
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.339
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.339
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.338
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.337
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.337
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.335
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.333
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.333
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.331
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.330
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.325
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.325
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.319
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.318
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.317
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.312
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.309
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.309
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.308
|
|
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
1 |
0.307
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.304
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.300
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.299
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.298
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.298
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.297
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.294
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.293
|
|
|
|
synaptic transmission cholinergic
|
GO:0007271 |
2 |
0.292
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.292
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.284
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
13 |
0.284
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.284
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.282
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.279
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.274
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.269
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.268
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.265
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.265
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.262
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.261
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.256
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.256
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.256
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.256
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.254
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.253
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.253
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.253
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.253
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.252
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.251
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.251
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.248
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.247
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.246
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.246
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.245
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.242
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.241
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.240
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.238
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.237
|
Mouse |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.236
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.234
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.233
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.231
|
|
|
|
negative regulation of dna templated transcription initiation
|
GO:2000143 |
3 |
0.229
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.228
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.226
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.222
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.221
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.218
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.216
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.216
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.215
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.214
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.213
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.211
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.211
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.211
|
|
|
|
heart valve development
|
GO:0003170 |
8 |
0.209
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.209
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.208
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.208
|
|
|
|
system process
|
GO:0003008 |
349 |
0.207
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.207
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.206
|
|
|
|
response to host
|
GO:0075136 |
2 |
0.204
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.203
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.202
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.200
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.200
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.197
|
|
|
|
negative regulation of schwann cell proliferation
|
GO:0010626 |
1 |
0.197
|
Human |
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.195
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.193
|
|
|
|
retinal blood vessel morphogenesis
|
GO:0061304 |
2 |
0.192
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.191
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.191
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.191
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.189
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.189
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.188
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.187
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.186
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.186
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.186
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.185
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.182
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.182
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.181
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.180
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.179
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.177
|
|
|
|
regulation of nodal signaling pathway involved in determination of left right asymmetry
|
GO:1900145 |
1 |
0.176
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.175
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.175
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.175
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.175
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.174
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.173
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.173
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.173
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.170
|
|
|
|
regulation of androgen receptor activity
|
GO:2000823 |
3 |
0.170
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.168
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.168
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.167
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.166
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.165
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.165
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.164
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.164
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.163
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
28 |
0.163
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.160
|
|
|
|
avoidance of host defenses
|
GO:0044413 |
2 |
0.160
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.156
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.155
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.155
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.155
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.155
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.153
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.153
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.151
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.150
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.148
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.148
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.146
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.145
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.145
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.143
|
|
|
|
sebaceous gland development
|
GO:0048733 |
1 |
0.141
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.140
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.140
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.138
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.138
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.136
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.135
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.134
|
Mouse |
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.134
|
Human |
|
|
vascular smooth muscle cell development
|
GO:0097084 |
1 |
0.132
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.132
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.132
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.131
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.131
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.130
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.130
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.130
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.128
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.128
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.127
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.127
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.127
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.127
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.126
|
Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.125
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.124
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.124
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.124
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.123
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.123
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.123
|
|
|
|
regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060260 |
8 |
0.123
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.121
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.121
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.118
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.117
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.116
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.115
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.115
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.115
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.114
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.114
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.114
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.114
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.113
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.113
|
Human Mouse |
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.113
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.112
|
|
|
|
artery morphogenesis
|
GO:0048844 |
7 |
0.110
|
|
|
|
vascular smooth muscle cell differentiation
|
GO:0035886 |
3 |
0.109
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.108
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.108
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.108
|
|
|
|
thalamus development
|
GO:0021794 |
2 |
0.108
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.106
|
|
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
1 |
0.105
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.105
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.104
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.103
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.102
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.102
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.102
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.101
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.100
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.099
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.098
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.097
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.094
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.093
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.093
|
|
|
|
regulation of dna templated transcription initiation
|
GO:2000142 |
9 |
0.092
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.092
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.091
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.089
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.089
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.088
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.087
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.087
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
10 |
0.086
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.086
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.084
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.083
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.083
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.082
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.081
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.081
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.080
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.080
|
|
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.080
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.080
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.080
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.080
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.079
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.079
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.079
|
|
|
|
glomerular basement membrane development
|
GO:0032836 |
3 |
0.079
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.078
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.078
|
|
|
|
negative regulation of bile acid biosynthetic process
|
GO:0070858 |
3 |
0.078
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.078
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.078
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.077
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.077
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.077
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.076
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.076
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.076
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.075
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.074
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.073
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.073
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.072
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.071
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.071
|
|
|
|
protein localization to synapse
|
GO:0035418 |
2 |
0.070
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.070
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.069
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.069
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.068
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.068
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.068
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.068
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.067
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.067
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.067
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.067
|
Mouse |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.066
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
18 |
0.066
|
|
|
|
vitamin d receptor signaling pathway
|
GO:0070561 |
4 |
0.066
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.065
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.065
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.065
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
15 |
0.064
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.064
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.064
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.064
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.063
|
Mouse |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.063
|
Mouse |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.062
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.062
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.062
|
|
|
|
ventricular septum development
|
GO:0003281 |
5 |
0.061
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.061
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.061
|
|
