Homo sapiens

47 known processes

SLX1B

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

(Aliases: FLJ23439,MGC2532,SLX1A,MGC5178,GIYD1,GIYD2)

SLX1B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide excision repair dna incision GO:0033683 7 0.999
ribonucleoside triphosphate metabolic process GO:0009199 412 0.807
response to cell cycle checkpoint signaling GO:0072396 4 0.800
dna catabolic process GO:0006308 49 0.713
cellular macromolecule catabolic process GO:0044265 380 0.711
regulation of telomere maintenance GO:0032204 13 0.685
response to dna integrity checkpoint signaling GO:0072402 4 0.669
response to biotic stimulus GO:0009607 276 0.636
dna catabolic process endonucleolytic GO:0000737 37 0.589
nucleoside triphosphate metabolic process GO:0009141 422 0.562
nucleotide excision repair GO:0006289 31 0.545
regulation of homeostatic process GO:0032844 121 0.419
oogenesis GO:0048477 2 0.413
response to dna damage checkpoint signaling GO:0072423 4 0.409
response to other organism GO:0051707 261 0.401
negative regulation of homeostatic process GO:0032845 59 0.347
negative regulation of cell cycle phase transition GO:1901988 89 0.336
recombinational repair GO:0000725 50 0.325
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.280
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.279
cellular response to dna damage stimulus GO:0006974 379 0.274
wound healing GO:0042060 115 0.237
modification dependent macromolecule catabolic process GO:0043632 212 0.227
negative regulation of chromosome organization GO:2001251 48 0.219
modification dependent protein catabolic process GO:0019941 209 0.218
atp catabolic process GO:0006200 157 0.217
regulation of mitotic cell cycle GO:0007346 189 0.199
dna repair GO:0006281 198 0.189
organophosphate catabolic process GO:0046434 430 0.182
proteasomal protein catabolic process GO:0010498 176 0.179
mitotic cell cycle GO:0000278 326 0.177
regulation of dna metabolic process GO:0051052 153 0.175
positive regulation of hydrolase activity GO:0051345 331 0.168
regulation of cell cycle GO:0051726 393 0.158
ribonucleoside triphosphate catabolic process GO:0009203 391 0.157
immune response GO:0006955 307 0.155
anatomical structure homeostasis GO:0060249 100 0.144
purine nucleotide catabolic process GO:0006195 405 0.136
ribonucleoside monophosphate metabolic process GO:0009161 187 0.127
determination of adult lifespan GO:0008340 2 0.127
nucleotide catabolic process GO:0009166 408 0.125
dna recombination GO:0006310 77 0.117
negative regulation of cell cycle process GO:0010948 121 0.110
cellular protein catabolic process GO:0044257 261 0.105
tissue migration GO:0090130 119 0.102
double strand break repair GO:0006302 101 0.101
negative regulation of organelle organization GO:0010639 126 0.099
glycosyl compound catabolic process GO:1901658 413 0.096
regulation of immune response GO:0050776 201 0.095
nucleoside catabolic process GO:0009164 408 0.095
response to wounding GO:0009611 168 0.095
response to external biotic stimulus GO:0043207 261 0.094
ribonucleoside catabolic process GO:0042454 406 0.093
purine ribonucleoside metabolic process GO:0046128 437 0.093
purine ribonucleoside catabolic process GO:0046130 398 0.091
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.084
purine ribonucleotide catabolic process GO:0009154 404 0.084
endomembrane system organization GO:0010256 196 0.080
cellular response to biotic stimulus GO:0071216 71 0.079
purine nucleoside triphosphate metabolic process GO:0009144 412 0.078
response to radiation GO:0009314 151 0.077
female gamete generation GO:0007292 2 0.077
negative regulation of telomere maintenance GO:0032205 9 0.077
inflammatory response GO:0006954 79 0.077
double strand break repair via homologous recombination GO:0000724 50 0.077
ion transmembrane transport GO:0034220 338 0.074
nuclear division GO:0000280 128 0.074
anatomical structure formation involved in morphogenesis GO:0048646 284 0.073
mitotic cell cycle process GO:1903047 286 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.072
negative regulation of catalytic activity GO:0043086 335 0.071
defense response GO:0006952 315 0.069
ameboidal type cell migration GO:0001667 135 0.068
ribonucleotide biosynthetic process GO:0009260 81 0.068
nitrogen compound transport GO:0071705 191 0.067
negative regulation of transferase activity GO:0051348 124 0.064
ribonucleotide catabolic process GO:0009261 405 0.062
regulation of cell morphogenesis GO:0022604 153 0.062
response to oxidative stress GO:0006979 121 0.062
cell development GO:0048468 328 0.059
positive regulation of gtpase activity GO:0043547 166 0.059
negative regulation of response to wounding GO:1903035 47 0.059
inflammatory response to antigenic stimulus GO:0002437 4 0.059
purine nucleotide biosynthetic process GO:0006164 84 0.058
multicellular organismal aging GO:0010259 3 0.057
negative regulation of cell cycle GO:0045786 193 0.057
regulation of establishment of protein localization GO:0070201 242 0.057
negative regulation of protein modification process GO:0031400 200 0.056
nucleoside phosphate catabolic process GO:1901292 412 0.054
carboxylic acid transport GO:0046942 63 0.054
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.054
cytokinesis GO:0000910 96 0.052
amino acid transport GO:0006865 28 0.051
purine nucleoside triphosphate catabolic process GO:0009146 392 0.051
immune effector process GO:0002252 159 0.049
amine metabolic process GO:0009308 44 0.049
ubiquitin dependent protein catabolic process GO:0006511 206 0.047
epithelium migration GO:0090132 119 0.047
cell morphogenesis GO:0000902 296 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.045
organic anion transport GO:0015711 103 0.045
negative regulation of protein metabolic process GO:0051248 391 0.045
gtp metabolic process GO:0046039 239 0.045
positive regulation of cellular catabolic process GO:0031331 284 0.044
nucleoside triphosphate catabolic process GO:0009143 394 0.044
dephosphorylation GO:0016311 209 0.044
negative regulation of gliogenesis GO:0014014 3 0.044
actomyosin contractile ring organization GO:0044837 1 0.043
protein catabolic process GO:0030163 325 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.043
ribonucleoprotein complex subunit organization GO:0071826 81 0.043
spermatid development GO:0007286 4 0.043
transmembrane transport GO:0055085 399 0.041
regulation of mitotic cell cycle phase transition GO:1901990 118 0.041
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.041
meiosis i GO:0007127 4 0.041
regulation of erk1 and erk2 cascade GO:0070372 99 0.041
anion transport GO:0006820 161 0.040
regulation of defense response GO:0031347 154 0.040
positive regulation of catabolic process GO:0009896 310 0.039
purine containing compound catabolic process GO:0072523 411 0.038
atp metabolic process GO:0046034 176 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
response to intra s dna damage checkpoint signaling GO:0072429 4 0.037
positive regulation of apoptotic process GO:0043065 246 0.036
epithelial cell migration GO:0010631 119 0.036
ribonucleoprotein complex biogenesis GO:0022613 116 0.035
regulation of cell migration GO:0030334 289 0.035
nucleoside monophosphate metabolic process GO:0009123 191 0.034
spermatid differentiation GO:0048515 4 0.034
fat cell differentiation GO:0045444 32 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.034
telomere maintenance GO:0000723 32 0.034
negative regulation of phosphorylation GO:0042326 174 0.034
negative regulation of immune response GO:0050777 40 0.033
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.032
extrinsic apoptotic signaling pathway GO:0097191 119 0.032
response to metal ion GO:0010038 84 0.032
regulation of protein localization GO:0032880 296 0.032
regulation of stress activated mapk cascade GO:0032872 84 0.032
nervous system development GO:0007399 293 0.032
regulation of map kinase activity GO:0043405 108 0.032
mitochondrion organization GO:0007005 156 0.031
erk1 and erk2 cascade GO:0070371 104 0.031
positive regulation of cellular component movement GO:0051272 181 0.031
oocyte differentiation GO:0009994 2 0.031
cell division GO:0051301 168 0.031
enzyme linked receptor protein signaling pathway GO:0007167 303 0.030
positive regulation of cellular component biogenesis GO:0044089 158 0.030
mitochondrial transport GO:0006839 60 0.029
spliceosomal snrnp assembly GO:0000387 28 0.029
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.029
guanosine containing compound metabolic process GO:1901068 244 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.029
negative regulation of cellular catabolic process GO:0031330 83 0.028
response to inorganic substance GO:0010035 127 0.028
organic acid transport GO:0015849 65 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
positive regulation of transport GO:0051050 336 0.027
innate immune response GO:0045087 178 0.027
stress activated mapk cascade GO:0051403 93 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
actin filament based process GO:0030029 224 0.027
cellular response to endogenous stimulus GO:0071495 336 0.026
hematopoietic or lymphoid organ development GO:0048534 186 0.026
cellular ketone metabolic process GO:0042180 80 0.026
defense response to other organism GO:0098542 129 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
regulation of jnk cascade GO:0046328 73 0.026
rho protein signal transduction GO:0007266 26 0.025
regulation of cellular protein catabolic process GO:1903362 96 0.025
regulation of protein transport GO:0051223 213 0.025
negative regulation of developmental process GO:0051093 247 0.025
negative regulation of response to external stimulus GO:0032102 83 0.024
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.024
negative regulation of protein phosphorylation GO:0001933 140 0.024
negative regulation of catabolic process GO:0009895 104 0.024
regulation of cellular component movement GO:0051270 334 0.024
regulation of cell cycle process GO:0010564 266 0.023
regulation of secretion GO:0051046 194 0.023
regulation of protein processing GO:0070613 150 0.023
regulation of response to wounding GO:1903034 101 0.023
microtubule based process GO:0007017 210 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
regulation of inflammatory response GO:0050727 46 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.023
regulation of ras protein signal transduction GO:0046578 155 0.023
regulation of cell motility GO:2000145 299 0.023
negative regulation of hydrolase activity GO:0051346 182 0.022
response to nitrosative stress GO:0051409 4 0.022
negative regulation of immune system process GO:0002683 136 0.022
response to light stimulus GO:0009416 87 0.022
positive regulation of cell death GO:0010942 263 0.022
mapk cascade GO:0000165 288 0.022
purine ribonucleotide biosynthetic process GO:0009152 79 0.022
membrane organization GO:0061024 292 0.021
cellular component morphogenesis GO:0032989 314 0.021
negative regulation of jnk cascade GO:0046329 16 0.021
secretion GO:0046903 254 0.021
organelle assembly GO:0070925 176 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.021
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
response to organic cyclic compound GO:0014070 204 0.020
mitotic cell cycle checkpoint GO:0007093 68 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
blood vessel development GO:0001568 172 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
single organismal cell cell adhesion GO:0016337 148 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
response to uv GO:0009411 73 0.020
gtp catabolic process GO:0006184 237 0.020
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.019
regulation of chromosome organization GO:0033044 103 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
blastocyst development GO:0001824 3 0.019
oxidation reduction process GO:0055114 396 0.019
g2 m transition of mitotic cell cycle GO:0000086 41 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
negative regulation of jun kinase activity GO:0043508 4 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
cranial nerve development GO:0021545 4 0.019
single organism cellular localization GO:1902580 332 0.019
positive regulation of gtp catabolic process GO:0033126 166 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
positive regulation of programmed cell death GO:0043068 249 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
ribonucleoprotein complex assembly GO:0022618 78 0.018
vasculature development GO:0001944 181 0.018
cell type specific apoptotic process GO:0097285 125 0.018
protein localization to organelle GO:0033365 280 0.018
vesicle organization GO:0016050 62 0.018
positive regulation of cellular component organization GO:0051130 376 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
cardiovascular system development GO:0072358 262 0.017
positive regulation of proteolysis GO:0045862 142 0.017
centrosome organization GO:0051297 58 0.017
regulation of immune effector process GO:0002697 91 0.017
tissue homeostasis GO:0001894 63 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
regulation of response to external stimulus GO:0032101 222 0.017
circulatory system development GO:0072359 262 0.017
angiogenesis GO:0001525 147 0.017
negative regulation of kinase activity GO:0033673 106 0.017
protein maturation GO:0051604 233 0.017
positive regulation of secretion GO:0051047 116 0.017
intracellular protein transport GO:0006886 270 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
cellular amine metabolic process GO:0044106 41 0.016
nerve development GO:0021675 4 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
maintenance of location GO:0051235 112 0.016
positive regulation of organelle organization GO:0010638 195 0.016
negative regulation of defense response GO:0031348 47 0.016
cell cycle phase transition GO:0044770 173 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
regulation of protein stability GO:0031647 87 0.015
regulation of intracellular transport GO:0032386 195 0.015
neutrophil activation involved in immune response GO:0002283 3 0.015
regulation of glial cell differentiation GO:0045685 3 0.015
single organism membrane organization GO:0044802 268 0.015
jnk cascade GO:0007254 80 0.015
rna processing GO:0006396 255 0.015
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
dna integrity checkpoint GO:0031570 71 0.015
organ morphogenesis GO:0009887 147 0.014
actin filament based movement GO:0030048 17 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
ribose phosphate biosynthetic process GO:0046390 82 0.014
cellular protein complex assembly GO:0043623 188 0.014
homotypic cell cell adhesion GO:0034109 47 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.014
myeloid leukocyte differentiation GO:0002573 60 0.014
endothelial cell migration GO:0043542 86 0.014
response to bacterium GO:0009617 144 0.014
secretion by cell GO:0032940 226 0.014
positive regulation of ras gtpase activity GO:0032320 117 0.014
cell part morphogenesis GO:0032990 137 0.014
covalent chromatin modification GO:0016569 254 0.013
nucleoside phosphate biosynthetic process GO:1901293 109 0.013
epithelial cell proliferation GO:0050673 128 0.013
cation transmembrane transport GO:0098655 238 0.013
protein dephosphorylation GO:0006470 81 0.013
golgi disassembly GO:0090166 2 0.013
positive regulation of protein transport GO:0051222 135 0.013
cytoplasmic transport GO:0016482 379 0.013
regulation of ion transmembrane transporter activity GO:0032412 72 0.013
response to virus GO:0009615 126 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
cell growth GO:0016049 160 0.013
replicative cell aging GO:0001302 3 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
cytoskeleton dependent cytokinesis GO:0061640 22 0.013
reproduction GO:0000003 63 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.012
cellular response to oxidative stress GO:0034599 85 0.012
sequestering of calcium ion GO:0051208 17 0.012
actin cytoskeleton organization GO:0030036 207 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
ras protein signal transduction GO:0007265 73 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
elastic fiber assembly GO:0048251 3 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
regulation of ion transport GO:0043269 189 0.012
cellular amino acid metabolic process GO:0006520 116 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
camp biosynthetic process GO:0006171 47 0.012
regulation of protein secretion GO:0050708 86 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.012
epithelial cell differentiation GO:0030855 141 0.012
action potential GO:0001508 34 0.012
regulation of wound healing GO:0061041 56 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
protein oligomerization GO:0051259 173 0.012
regulation of rho protein signal transduction GO:0035023 79 0.012
chemical homeostasis GO:0048878 306 0.011
regulation of transmembrane transport GO:0034762 139 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
regulation of gtpase activity GO:0043087 180 0.011
histone modification GO:0016570 251 0.011
head development GO:0060322 108 0.011
amide transport GO:0042886 76 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
positive regulation of cell motility GO:2000147 177 0.011
sensory perception of mechanical stimulus GO:0050954 37 0.011
cell cell signaling GO:0007267 155 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
regulation of ion homeostasis GO:2000021 73 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
rna splicing GO:0008380 131 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
negative regulation of dna metabolic process GO:0051053 57 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
peptidyl tyrosine dephosphorylation GO:0035335 36 0.010
positive regulation of angiogenesis GO:0045766 51 0.010
positive regulation of mitotic cell cycle GO:0045931 60 0.010
cell projection assembly GO:0030031 126 0.010
protein modification by small protein conjugation GO:0032446 342 0.010
molting cycle GO:0042303 28 0.010

SLX1B disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.741
congenital hypoplastic anemia DOID:1342 26 0.662
aplastic anemia DOID:12449 30 0.662
bone marrow disease DOID:4961 31 0.662
anemia DOID:2355 55 0.662
hematopoietic system disease DOID:74 100 0.662
disease of metabolism DOID:0014667 295 0.075
xeroderma pigmentosum DOID:0050427 8 0.067
inherited metabolic disorder DOID:655 242 0.038
musculoskeletal system disease DOID:17 223 0.037
cardiovascular system disease DOID:1287 106 0.033
artery disease DOID:0050828 23 0.030
vascular disease DOID:178 25 0.030
connective tissue disease DOID:65 109 0.028
osteochondrodysplasia DOID:2256 35 0.025
bone development disease DOID:0080006 55 0.025
bone disease DOID:0080001 88 0.025
amino acid metabolic disorder DOID:9252 50 0.019
fanconi s anemia DOID:13636 16 0.018