|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
evasion or tolerance of host defenses by virus
|
GO:0019049 |
2 |
1.000
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
1.000
|
Human |
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
1.000
|
Human |
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
1.000
|
Human Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
1.000
|
|
|
|
response to host defenses
|
GO:0052200 |
2 |
1.000
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
1.000
|
|
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
1.000
|
Human |
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
1 |
1.000
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
1.000
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
1.000
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
1.000
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
1.000
|
Human |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
1.000
|
Human |
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
1.000
|
|
|
|
avoidance of defenses of other organism involved in symbiotic interaction
|
GO:0051832 |
2 |
1.000
|
|
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
1.000
|
Human |
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
1.000
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
1.000
|
Human |
|
|
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900224 |
1 |
1.000
|
Human |
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
1.000
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
1.000
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
1.000
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
1.000
|
Mouse |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
1.000
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
1.000
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
1.000
|
Mouse |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
1.000
|
Human |
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
1.000
|
Human |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
1.000
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
|
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
1.000
|
Human |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
1.000
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
1.000
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
1.000
|
Mouse |
|
|
evasion or tolerance of defenses of other organism involved in symbiotic interaction
|
GO:0051834 |
2 |
1.000
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
1.000
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
1.000
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
1.000
|
|
|
|
positive regulation of mesoderm development
|
GO:2000382 |
2 |
1.000
|
Human |
|
|
response to host
|
GO:0075136 |
2 |
1.000
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
1.000
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry
|
GO:1900094 |
1 |
1.000
|
Human |
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
1.000
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.999
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.999
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.999
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.999
|
|
|
|
regulation of nodal signaling pathway involved in determination of left right asymmetry
|
GO:1900145 |
1 |
0.999
|
Human |
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.999
|
Mouse |
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
1 |
0.999
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.999
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.999
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.999
|
Mouse |
|
|
kidney development
|
GO:0001822 |
53 |
0.999
|
Mouse |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.999
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.999
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.999
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.999
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.999
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.999
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.999
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.999
|
Human |
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.999
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.999
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.999
|
Mouse |
|
|
stem cell development
|
GO:0048864 |
69 |
0.999
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.998
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.998
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.998
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.998
|
Mouse |
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.998
|
Human |
|
|
mesoderm development
|
GO:0007498 |
14 |
0.998
|
Human Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.998
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.998
|
Mouse |
|
|
regulation of mesoderm development
|
GO:2000380 |
4 |
0.998
|
Human |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.998
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.997
|
Mouse |
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.997
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.997
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.997
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.997
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.997
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.996
|
|
|
|
regulation of smad protein complex assembly
|
GO:0010990 |
4 |
0.996
|
Human |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.996
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.996
|
Human Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.996
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.996
|
Human |
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.996
|
Mouse |
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.996
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.996
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.996
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.995
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.995
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.995
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.995
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.995
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.995
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.994
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.994
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.994
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.994
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.994
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.993
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.993
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.993
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.993
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.993
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.993
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.992
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.992
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.992
|
Mouse |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.992
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.992
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.992
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.992
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.992
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.991
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.991
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.991
|
Human Mouse |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.990
|
Mouse |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.990
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.990
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.990
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.990
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.990
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.989
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.988
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.988
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.988
|
Human |
|
|
nuclear import
|
GO:0051170 |
106 |
0.987
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.986
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.986
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.986
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.986
|
|
|
|
positive regulation of catenin import into nucleus
|
GO:0035413 |
9 |
0.986
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.985
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.985
|
Human Rat |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.984
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.984
|
Mouse |
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.984
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.984
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.982
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.982
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.982
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.981
|
|
|
|
growth
|
GO:0040007 |
202 |
0.981
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.981
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.981
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.981
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.981
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.980
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.979
|
Mouse |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.979
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.977
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.977
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.977
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.977
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.977
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.977
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.974
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.974
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.973
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.973
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.970
|
Human Mouse |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.969
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.969
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.968
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.966
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.965
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.965
|
Human |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.965
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.965
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.963
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.963
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.963
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.962
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.962
|
Mouse |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.962
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.962
|
Mouse |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.962
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.959
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.959
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.957
|
Human |
|
|
transforming growth factor beta2 production
|
GO:0032906 |
6 |
0.957
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.957
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.956
|
Human |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.956
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.955
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.952
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.951
|
Mouse Rat |
|
|
protein targeting
|
GO:0006605 |
187 |
0.951
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.951
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.949
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.949
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.948
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.947
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.947
|
Human |
|
|
stem cell division
|
GO:0017145 |
2 |
0.945
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.945
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.944
|
|
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.944
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.943
|
Mouse |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.941
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.940
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.939
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.936
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.936
|
Human Mouse |
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.935
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.935
|
Mouse |
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.935
|
Human |
|
|
protein import
|
GO:0017038 |
130 |
0.935
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.934
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.934
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.933
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.933
|
Rat |
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.930
|
Worm |
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.930
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.927
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.927
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.927
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.925
|
|
|
|
negative regulation of androgen receptor activity
|
GO:2000824 |
2 |
0.925
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.924
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.924
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.923
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
7 |
0.923
|
Human |
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
22 |
0.923
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.921
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.918
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.916
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.915
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.914
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.910
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.907
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.906
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.902
|
Human |
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.897
|
|
|
|
nodal signaling pathway
|
GO:0038092 |
5 |
0.895
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.894
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.891
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.888
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.887
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.886
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.886
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.885
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.885
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.883
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.882
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.881
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.878
|
Human |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.876
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.875
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.874
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.873
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.872
|
Mouse |
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.871
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.870
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.869
|
|
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
8 |
0.868
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.867
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.864
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.864
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.863
|
Human |
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.862
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.853
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.849
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.849
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.846
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
0.846
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.845
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.844
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.844
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.841
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.840
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.837
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.836
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.832
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.831
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.827
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.827
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.826
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.826
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.825
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
6 |
0.822
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.821
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.820
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.819
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.818
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.818
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.817
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.816
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.816
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.816
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.814
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.814
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.813
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.813
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.811
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.809
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.807
|
Rat |
|
|
histone acetylation
|
GO:0016573 |
93 |
0.799
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.798
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.795
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.793
|
Mouse |
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.791
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.791
|
Human Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.789
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.785
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
1 |
0.783
|
|
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.781
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.781
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.780
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.779
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.778
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.776
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.774
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.773
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.773
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.768
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.765
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.765
|
Human |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.764
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.763
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.760
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.759
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.756
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.754
|
|
|
|
regulation of transforming growth factor beta production
|
GO:0071634 |
13 |
0.753
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.751
|
Rat |
|
|
positive regulation of multicellular organism growth
|
GO:0040018 |
6 |
0.746
|
Worm |
|
|
palate development
|
GO:0060021 |
13 |
0.744
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.743
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.741
|
Human Rat |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.741
|
Mouse |
|
|
response to laminar fluid shear stress
|
GO:0034616 |
8 |
0.740
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.739
|
Mouse |
|
|
neuron development
|
GO:0048666 |
113 |
0.739
|
|
|
|
heart valve formation
|
GO:0003188 |
2 |
0.738
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.738
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.736
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.728
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.727
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.727
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.726
|
Human |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.723
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.721
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.717
|
Mouse |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.715
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.710
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.709
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.709
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.707
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.707
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.704
|
|
|
|
avoidance of host defenses
|
GO:0044413 |
2 |
0.702
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.700
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.700
|
Human |
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.695
|
Mouse |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.695
|
Human |
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
12 |
0.692
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.687
|
Worm |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.683
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.683
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.680
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.677
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.677
|
Mouse |
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.677
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.675
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.672
|
|
|
|
cellular protein complex localization
|
GO:0034629 |
8 |
0.668
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.666
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.662
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.661
|
|
|
|
negative regulation of schwann cell proliferation
|
GO:0010626 |
1 |
0.661
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.659
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.658
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.655
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.651
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.650
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.642
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.640
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.639
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.638
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.637
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.635
|
Worm |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.635
|
|
|
|
respiratory tube development
|
GO:0030323 |
20 |
0.632
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.631
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.626
|
Human Rat |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.624
|
|
|
|
response to fluid shear stress
|
GO:0034405 |
14 |
0.623
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.622
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
14 |
0.620
|
|
|
|
embryonic axis specification
|
GO:0000578 |
5 |
0.618
|
Human |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.617
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.615
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.610
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.610
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.607
|
Human |
|
|
brain development
|
GO:0007420 |
97 |
0.607
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.604
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.594
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.593
|
Human Rat |
|
|
oogenesis
|
GO:0048477 |
2 |
0.588
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.587
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
15 |
0.583
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.576
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.575
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.572
|
Worm |
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.570
|
Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.568
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.567
|
Human |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.566
|
|
|
|
positive regulation of lipid storage
|
GO:0010884 |
10 |
0.565
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.565
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.565
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.563
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.559
|
Human Mouse Rat |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.558
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.558
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.556
|
|
|
|
response to bmp
|
GO:0071772 |
8 |
0.555
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.555
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.554
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.554
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
2 |
0.553
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.551
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.549
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.549
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.546
|
|
|
|
positive regulation of activin receptor signaling pathway
|
GO:0032927 |
6 |
0.542
|
Human |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.541
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.539
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.534
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.532
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.528
|
Worm |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.528
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.526
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.525
|
|
|
|
somite development
|
GO:0061053 |
7 |
0.524
|
Mouse |
|
|
pericardium development
|
GO:0060039 |
2 |
0.519
|
Mouse |
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.516
|
|
|
|
response to sterol
|
GO:0036314 |
14 |
0.514
|
Human |
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.510
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.509
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.507
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.505
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.501
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.500
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.497
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.495
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.495
|
Mouse |
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.495
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.495
|
Mouse |
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.495
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.491
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.489
|
Human |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.489
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.486
|
Mouse Worm |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.483
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.482
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.479
|
Human |
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.479
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.475
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to oxidative stress
|
GO:0043619 |
5 |
0.473
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.473
|
|
|
|
determination of left right asymmetry in lateral mesoderm
|
GO:0003140 |
1 |
0.472
|
Human |
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.472
|
Mouse |
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.470
|
Worm |
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.469
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
10 |
0.468
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.467
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.461
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.458
|
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.454
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.453
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.451
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.447
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.444
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.443
|
|
|
|
positive regulation of dna binding
|
GO:0043388 |
17 |
0.443
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.437
|
Rat |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.437
|
|
|
|
limb development
|
GO:0060173 |
23 |
0.434
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.434
|
Human |
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.433
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
11 |
0.430
|
Human Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.425
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.423
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.423
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.421
|
Mouse |
|
|
amide transport
|
GO:0042886 |
76 |
0.419
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
9 |
0.413
|
Mouse |
