|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
1.000
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
1.000
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
1.000
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
1.000
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
1.000
|
Human |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
1.000
|
Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
Human Worm |
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
1.000
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
1.000
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
1.000
|
Fly |
|
|
chromatin organization
|
GO:0006325 |
351 |
1.000
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
1.000
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
1.000
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
1.000
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
1.000
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.999
|
Human Mouse Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.999
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.999
|
Mouse |
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.999
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.999
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.999
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.998
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.998
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.998
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.998
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.998
|
Human |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.998
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.998
|
Mouse |
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.998
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.998
|
Human Fly |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.998
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.997
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.997
|
Human Mouse |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.997
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.996
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.996
|
Human Mouse |
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.995
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.995
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.995
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.995
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.995
|
Fly |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.995
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.994
|
Human Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.994
|
Worm Fly |
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.994
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.994
|
Human Mouse |
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.994
|
|
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.993
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.993
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.992
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.992
|
Human |
|
|
connective tissue development
|
GO:0061448 |
39 |
0.992
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.990
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.989
|
Human |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.989
|
|
|
|
regulation of nodal signaling pathway
|
GO:1900107 |
1 |
0.988
|
Human |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.988
|
Human Mouse |
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
0.987
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.987
|
Mouse Fly |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.987
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.986
|
Human Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.985
|
Human Mouse Worm Fly |
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
1 |
0.984
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.983
|
Human Mouse |
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.982
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.982
|
Human Mouse |
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.980
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.979
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.978
|
Human |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.977
|
Human Mouse |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.977
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.976
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.975
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.975
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.974
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.973
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.973
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.972
|
Human Mouse |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.971
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.970
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.970
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.970
|
Human Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.970
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.970
|
Human Mouse Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.967
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.966
|
Human |
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
0.966
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.964
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.963
|
Human |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.963
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.960
|
Mouse |
|
|
protein deacylation
|
GO:0035601 |
39 |
0.959
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.958
|
Human Mouse Fly |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.957
|
Human Mouse |
|
|
negative regulation of schwann cell proliferation
|
GO:0010626 |
1 |
0.957
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.957
|
|
|
|
regulation of nodal signaling pathway involved in determination of left right asymmetry
|
GO:1900145 |
1 |
0.956
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.956
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.954
|
Human Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.953
|
Human Mouse |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.953
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.951
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.951
|
Human |
|
|
trna transport
|
GO:0051031 |
1 |
0.949
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.949
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.948
|
Human Mouse |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.948
|
Human Worm |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.946
|
Human Mouse |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.946
|
Human |
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.943
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.942
|
Human |
|
|
trna export from nucleus
|
GO:0006409 |
1 |
0.941
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.940
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.939
|
Human Mouse |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.939
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.938
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.937
|
Human Mouse |
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.936
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.935
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.931
|
Human Mouse Fly |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.931
|
Human Worm |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.930
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.929
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.926
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.926
|
Human |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.921
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.921
|
Human Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.920
|
Human |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.919
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.917
|
Human Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.916
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.915
|
Mouse Fly |
|
|
dissemination or transmission of organism from other organism involved in symbiotic interaction
|
GO:0051821 |
1 |
0.912
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.909
|
Human |
|
|
dissemination or transmission of symbiont from host
|
GO:0044007 |
1 |
0.906
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.906
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.904
|
Human Mouse |
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
1 |
0.902
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.900
|
Mouse Fly |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.900
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.900
|
Mouse |
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.900
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.898
|
Human Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.894
|
Human Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.891
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010768 |
1 |
0.891
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.888
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.888
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.887
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.886
|
Human Mouse |
|
|
heart development
|
GO:0007507 |
95 |
0.884
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.883
|
Human |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.882
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
0.880
|
Human |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.867
|
|
|
|
transmission of virus
|
GO:0019089 |
1 |
0.867
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.861
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.860
|
Human |
|
|
progesterone receptor signaling pathway
|
GO:0050847 |
3 |
0.858
|
|
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.857
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.857
|
Human |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.855
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.855
|
Worm Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.852
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.852
|
Human Mouse |
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.851
|
|
|
|
polyprenol metabolic process
|
GO:0016093 |
3 |
0.850
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.848
|
Human Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.846
|
Human |
|
|
viral process
|
GO:0016032 |
146 |
0.845
|
Human |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.843
|
Human Mouse |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.843
|
Mouse Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.837
|
Human |
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.836
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.834
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.833
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.830
|
Human |
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.829
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.829
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.825
|
Human Mouse |
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.822
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.818
|
Human |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.817
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.817
|
Human Mouse |
|
|
growth
|
GO:0040007 |
202 |
0.813
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010767 |
1 |
0.808
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.806
|
Human |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.804
|
Human |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.798
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.798
|
Human Mouse Fly |
|
|
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900224 |
1 |
0.796
|
Human |
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.794
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.794
|
Human Mouse |
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.787
|
Human |
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.783
|
Worm Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.781
|
Human Mouse |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.776
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.775
|
Human Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.774
|
Human Mouse Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.767
|
Mouse |
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.765
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.763
|
Human |
|
|
protein k29 linked ubiquitination
|
GO:0035519 |
4 |
0.757
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.754
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.754
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.749
|
Human |
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.747
|
Mouse |
|
|
histone modification
|
GO:0016570 |
251 |
0.746
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.729
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.728
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.726
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.721
|
Human |
|
|
evasion or tolerance of defenses of other organism involved in symbiotic interaction
|
GO:0051834 |
2 |
0.720
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.716
|
Mouse Fly |
|
|
regulation of multivesicular body size
|
GO:0010796 |
1 |
0.713
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.705
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.703
|
Human Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.695
|
Fly |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.694
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.685
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.684
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.682
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.680
|
Worm |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.677
|
Human Mouse |
|
|
kidney development
|
GO:0001822 |
53 |
0.670
|
Mouse |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.669
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.664
|
Human Mouse Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.662
|
Human Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.658
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.656
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.647
|
Human |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.647
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.647
|
Human Mouse |
|
|
eye development
|
GO:0001654 |
42 |
0.647
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.641
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.639
|
Human |
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.636
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.636
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.635
|
Human |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.628
|
Mouse |
|
|
nose development
|
GO:0043584 |
2 |
0.627
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.626
|
Human |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.621
|
Human |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.617
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.614
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.614
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.610
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.605
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.599
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.596
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.596
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.590
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.590
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.586
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.586
|
Fly |
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.584
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.584
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.579
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.578
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.574
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.572
|
Mouse Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.570
|
Human Mouse |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.567
|
Human Mouse Fly |
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.565
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.565
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.565
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.564
|
Human Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.563
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.553
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.553
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.553
|
|
|
|
negative regulation of androgen receptor activity
|
GO:2000824 |
2 |
0.553
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.551
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.548
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.545
|
|
|
|
system process
|
GO:0003008 |
349 |
0.539
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.538
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.534
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.533
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.532
|
Human |
|
|
response to drug
|
GO:0042493 |
81 |
0.528
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.527
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.524
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.523
|
Mouse Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.521
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.519
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.518
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.514
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.509
|
Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.509
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.504
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.501
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.499
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.493
|
Human Mouse |
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.489
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.489
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.488
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.487
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.480
|
Mouse |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.478
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.477
|
|
|
|
quinone metabolic process
|
GO:1901661 |
18 |
0.465
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.465
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.463
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.462
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.462
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.458
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.455
|
Human |
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
1 |
0.452
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.449
|
Human Mouse |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.449
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.448
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.447
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.446
|
Human |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.443
|
Mouse |
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.440
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.437
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.436
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.436
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.434
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.428
|
Mouse |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.422
|
Mouse |
|
|
pharynx development
|
GO:0060465 |
1 |
0.419
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.414
|
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.410
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.410
|
|
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.408
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.401
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.399
|
Human |
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.399
|
Human |
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.399
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.398
|
Fly |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.397
|
Human Mouse Fly |
|
|
cell fate specification
|
GO:0001708 |
8 |
0.396
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.391
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.390
|
Human Mouse |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.385
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.385
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.384
|
Mouse |
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.383
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.383
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.382
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.381
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.380
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.379
|
Human |
|
|
positive regulation of mesoderm development
|
GO:2000382 |
2 |
0.377
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.375
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.374
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.372
|
Mouse |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.370
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.367
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.366
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.366
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.366
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.366
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.363
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.360
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.359
|
Human |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.358
|
Worm Fly |
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.357
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.355
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.355
|
Mouse |
|
|
dolichol metabolic process
|
GO:0019348 |
3 |
0.349
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.349
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.346
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.338
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.337
|
|
|
|
regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060260 |
8 |
0.337
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.334
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.330
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.329
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.329
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.328
|
Worm |
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.325
|
Human |
|
|
cartilage development
|
GO:0051216 |
31 |
0.325
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.325
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.324
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.321
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.320
|
Mouse |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.317
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.313
|
Fly |
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.312
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.312
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.312
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.308
|
Worm Fly |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.308
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.306
|
Human |
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.305
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.305
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.304
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.302
|
Human Mouse Fly |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.301
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.296
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.294
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.293
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.291
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.291
|
Fly |
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.287
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.287
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.286
|
|
|
|
positive regulation of catenin import into nucleus
|
GO:0035413 |
9 |
0.285
|
Human |
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.284
|
Mouse |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.282
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.276
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.272
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.271
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.271
|
|
|
|
response to host defenses
|
GO:0052200 |
2 |
0.271
|
Human |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.268
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.267
|
Mouse |
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.264
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.263
|
Mouse Worm Fly |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.263
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.263
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.262
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.260
|
Human Mouse |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.258
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.257
|
|
|
|
negative regulation of androgen receptor signaling pathway
|
GO:0060766 |
10 |
0.256
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.255
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.254
|
Human Mouse |
|
|
regionalization
|
GO:0003002 |
29 |
0.253
|
Human Mouse Fly |
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.251
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.251
|
Human |
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.250
|
|
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.249
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry
|
GO:1900094 |
1 |
0.248
|
Human |
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
4 |
0.247
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.247
|
Human |
|
|
mesonephros development
|
GO:0001823 |
17 |
0.246
|
Mouse |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.244
|
Human Mouse |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.244
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.241
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.240
|
Human |
|
|
isoprenoid biosynthetic process
|
GO:0008299 |
9 |
0.238
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.237
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.237
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.236
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.231
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.231
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.228
|
Human |
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.228
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.227
|
|
|
|
quinone biosynthetic process
|
GO:1901663 |
6 |
0.226
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.225
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.225
|
Human |
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.224
|
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.223
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.223
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.223
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.222
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.220
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.220
|
|
|
|
regulation of dna templated transcription initiation
|
GO:2000142 |
9 |
0.220
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.219
|
Human Mouse |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.219
|
|
|
|
regulation of fatty acid biosynthetic process
|
GO:0042304 |
9 |
0.219
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.218
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.217
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.216
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.216
|
Mouse |
|
|
cell growth
|
GO:0016049 |
160 |
0.215
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.215
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.214
|
|
|
|
positive regulation of fatty acid metabolic process
|
GO:0045923 |
11 |
0.212
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.212
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.208
|
Mouse Fly |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.207
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.206
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.205
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.204
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.204
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.203
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.201
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.201
|
Human Mouse |
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.201
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.199
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.199
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.198
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.198
|
Human |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.197
|
Mouse Fly |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.195
|
Human |
