|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
1.000
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
1.000
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
1.000
|
Human |
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
1.000
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
1.000
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
1.000
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
1.000
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
1.000
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
1.000
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
1.000
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
1.000
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
1.000
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
1.000
|
Human |
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
1.000
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.999
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.999
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
0.999
|
Human |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.999
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.999
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.999
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.999
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.999
|
Human Fly |
|
|
response to sterol
|
GO:0036314 |
14 |
0.999
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.998
|
Human Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.998
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.998
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.998
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.998
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.997
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.996
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.996
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.996
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.996
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.995
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.995
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.995
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.995
|
Human |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.994
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.994
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.994
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.993
|
Human |
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.993
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.993
|
Human |
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.992
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.991
|
Human |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.991
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.991
|
Human |
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.991
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.990
|
Human |
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.990
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.988
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.987
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.987
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.987
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.986
|
Human Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.986
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.986
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.985
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.984
|
Human |
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.984
|
|
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.983
|
Human |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.982
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.982
|
Human |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.982
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.981
|
|
|
|
evasion or tolerance of host defenses by virus
|
GO:0019049 |
2 |
0.980
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.979
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.979
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.979
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.978
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.977
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.976
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.975
|
Human |
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.975
|
Human |
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.974
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.973
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.973
|
Human |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.972
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.972
|
Mouse Fly |
|
|
nodal signaling pathway
|
GO:0038092 |
5 |
0.971
|
Human |
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.969
|
Mouse |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.969
|
Human |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.969
|
Human |
|
|
positive regulation of mesenchymal stem cell differentiation
|
GO:2000741 |
4 |
0.969
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.968
|
Human |
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.967
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.967
|
Human |
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.966
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.964
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.964
|
Fly |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.963
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.963
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.962
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.962
|
Human |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.961
|
Human |
|
|
positive regulation of male gonad development
|
GO:2000020 |
3 |
0.960
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.960
|
Human |
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.960
|
Human |
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
0.957
|
|
|
|
regulation of mesoderm development
|
GO:2000380 |
4 |
0.957
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.957
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.956
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.955
|
Human |
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.955
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.954
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.952
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.952
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.952
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.950
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.947
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.946
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.945
|
Human |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.943
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.941
|
Human |
|
|
determination of left right asymmetry in lateral mesoderm
|
GO:0003140 |
1 |
0.940
|
Human |
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.940
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.940
|
Human |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.940
|
Mouse Fly |
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
4 |
0.939
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.939
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.939
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.939
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.939
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.938
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.937
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.937
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.935
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.935
|
|
|
|
avoidance of defenses of other organism involved in symbiotic interaction
|
GO:0051832 |
2 |
0.934
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.931
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.928
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.927
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.926
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.926
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.924
|
|
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.923
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.922
|
Fly |
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.921
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.921
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.920
|
Fly |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.919
|
Human |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.919
|
Fly |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.917
|
Human |
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.916
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.913
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.912
|
Human |
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.911
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.911
|
Mouse |
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.911
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.910
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.909
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.907
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.907
|
Mouse Fly |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.906
|
Human |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.906
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.906
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.904
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.904
|
Human |
|
|
cartilage development
|
GO:0051216 |
31 |
0.904
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.903
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.899
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.898
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
9 |
0.894
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.893
|
Human |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.893
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.890
|
Human |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.887
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.887
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.887
|
Mouse Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.886
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.885
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.884
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.884
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.882
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.881
|
Fly |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.881
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.880
|
Human |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.876
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.876
|
|
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.872
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.867
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.858
|
Human |
|
|
mitral valve development
|
GO:0003174 |
3 |
0.856
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.853
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.853
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.849
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.849
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.845
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.845
|
Human Fly |
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.842
|
Fly |
|
|
regionalization
|
GO:0003002 |
29 |
0.842
|
Human Fly |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.841
|
Human |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.836
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.835
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.834
|
Mouse |
|
|
response to wounding
|
GO:0009611 |
168 |
0.833
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.833
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.832
|
Human Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.824
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.824
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.818
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.815
|
Mouse |
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.809
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.808
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.804
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.804
|
Human Fly |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.799
|
Human |
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.799
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.790
|
Human |
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.788
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.787
|
Human |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.779
|
Mouse Fly |
|
|
response to host defenses
|
GO:0052200 |
2 |
0.778
|
Human |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.776
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.775
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.774
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.773
|
|
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
0.772
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.772
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.771
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.769
|
Mouse |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.768
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.763
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.763
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.758
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.757
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.756
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.752
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.751
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.748
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.744
|
Human |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.743
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.739
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.737
|
Human |
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.735
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.731
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.729
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.727
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.726
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.723
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.721
|
|
|
|
regulation of male gonad development
|
GO:2000018 |
4 |
0.717
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.717
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.716
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.715
|
Mouse |
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.715
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.713
|
Human |
|
|
positive regulation of cartilage development
|
GO:0061036 |
7 |
0.704
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.704
|
|
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.703
|
Human |
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.702
|
Human |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.691
|
Human |
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.691
|
|
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
1 |
0.688
|
Human |
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.685
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.685
|
|
|
|
chondrocyte differentiation involved in endochondral bone morphogenesis
|
GO:0003413 |
1 |
0.683
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.681
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.679
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.678
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.672
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.668
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.664
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.663
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.662
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.656
|
Human |
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.656
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.651
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.649
|
Human |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.648
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.647
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.646
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.643
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.641
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.639
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.638
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.634
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.634
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.632
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.631
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.629
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.621
|
Human |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.618
|
|
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
1 |
0.613
|
Human |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.609
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.609
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.608
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.604
|
Human |
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.602
|
Human |
|
|
protein targeting
|
GO:0006605 |
187 |
0.602
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.602
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.601
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.599
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.599
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.598
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.596
|
Fly |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.595
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.593
|
Mouse Fly |
|
|
positive regulation of reproductive process
|
GO:2000243 |
9 |
0.591
|
|
|
|
negative regulation of peptidyl serine phosphorylation
|
GO:0033137 |
8 |
0.586
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.584
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.583
|
Human Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.581
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.580
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.579
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.575
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.575
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.573
|
Mouse |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.573
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.573
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.570
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.570
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.570
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.570
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.567
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.563
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.559
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.557
|
Mouse |
|
|
ossification
|
GO:0001503 |
121 |
0.557
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.554
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.554
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.550
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.548
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.545
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.544
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.544
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.543
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.542
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.541
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.539
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.538
|
Human |
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.536
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.536
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.534
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.533
|
Human |
|
|
protein stabilization
|
GO:0050821 |
64 |
0.533
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.531
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.531
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.530
|
|
|
|
head development
|
GO:0060322 |
108 |
0.530
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
2 |
0.526
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.521
|
Human |
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
0.521
|
|
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
0.517
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.515
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.515
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.512
|
|
|
|
positive regulation of activin receptor signaling pathway
|
GO:0032927 |
6 |
0.508
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.505
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.504
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.503
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.502
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.502
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.502
|
Mouse |
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
0.502
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.492
|
Fly |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.489
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.484
|
|
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.482
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.481
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.480
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.477
|
Mouse |
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.477
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.476
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.474
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.474
|
Human |
|
|
atrial septum development
|
GO:0003283 |
8 |
0.474
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.470
|
Human |
|
|
response to host
|
GO:0075136 |
2 |
0.470
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.469
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.466
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.459
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.459
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.458
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.457
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.457
|
|
|
|
n terminal peptidyl lysine acetylation
|
GO:0018076 |
4 |
0.454
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.453
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.444
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.443
|
Human |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.438
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.433
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.424
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.423
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.422
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.420
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.419
|
Human |
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.417
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.415
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.413
|
|
|
|
positive regulation of catenin import into nucleus
|
GO:0035413 |
9 |
0.413
|
Human |
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
0.411
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.410
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.409
|
Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.409
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.404
|
Human Fly |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.400
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.400
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.393
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.393
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.393
|
Human |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.393
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.392
|
Human Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.391
|
Human |
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
0.391
|
Human |
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.390
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.389
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.387
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.387
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.381
|
Mouse |
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
0.381
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.379
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.378
|
Human |
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.377
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.371
|
Human |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.369
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.368
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.366
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.364
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.364
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.362
|
Human |
|
|
response to bmp
|
GO:0071772 |
8 |
0.359
|
|
|
|
growth
|
GO:0040007 |
202 |
0.358
|
Human Fly |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.356
|
|
|
|
system process
|
GO:0003008 |
349 |
0.355
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.354
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.352
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.349
|
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.348
|
|
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.347
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.346
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.344
|
|
|
|
regulation of smad protein complex assembly
|
GO:0010990 |
4 |
0.340
|
Human |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.339
|
|
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
0.338
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.336
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.336
|
Fly |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.335
|
Human |
|
|
protein processing
|
GO:0016485 |
226 |
0.335
|
Human |
|
|
dna damage response detection of dna damage
|
GO:0042769 |
3 |
0.333
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.331
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.330
|
Human |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.329
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.329
|
Mouse Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.328
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.328
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.326
|
Mouse |
|
|
regulation of nodal signaling pathway involved in determination of left right asymmetry
|
GO:1900145 |
1 |
0.324
|
Human |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.321
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.319
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.314
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.313
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.311
|
Mouse |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.310
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.308
|
Human |
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
6 |
0.305
|
Human |
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.305
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.305
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.303
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.303
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.302
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.301
|
Human |
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.300
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.299
|
Human |
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.299
|
Fly |
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.298
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.297
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.297
|
Human Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.297
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.295
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.295
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.293
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.292
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.292
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.290
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.287
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.286
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.284
|
Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.282
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.280
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.280
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.279
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.278
|
Human |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.276
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.275
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010767 |
1 |
0.274
|
|
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.274
|
|
|
|
avoidance of host defenses
|
GO:0044413 |
2 |
0.269
|
Human |
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.269
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.267
|
|
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.265
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.263
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.263
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.263
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.261
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.261
|
|
