Homo sapiens

102 known processes

SMC1A

structural maintenance of chromosomes 1A

(Aliases: CDLS2,KIAA0178,DKFZp686L19178,SMC1alpha,SMC1,DXS423E,SMC1L1,SB1.8,MGC138332,SMCB)

SMC1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic chromosome segregation GO:0045132 4 0.999
sister chromatid cohesion GO:0007062 24 0.999
mitotic sister chromatid cohesion GO:0007064 12 0.993
Yeast
negative regulation of cell cycle GO:0045786 193 0.988
negative regulation of dna endoreduplication GO:0032876 5 0.986
negative regulation of dna replication GO:0008156 29 0.985
double strand break repair GO:0006302 101 0.980
Yeast
dna dependent dna replication GO:0006261 44 0.979
chromosome segregation GO:0007059 114 0.976
sister chromatid segregation GO:0000819 54 0.969
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.964
protein localization to chromatin GO:0071168 11 0.960
organelle fission GO:0048285 149 0.959
Yeast Mouse
negative regulation of cell cycle process GO:0010948 121 0.938
dna repair GO:0006281 198 0.935
Yeast
cohesin localization to chromatin GO:0071921 4 0.933
dna replication GO:0006260 116 0.910
regulation of dna metabolic process GO:0051052 153 0.868
internal peptidyl lysine acetylation GO:0018393 97 0.867
regulation of meiotic cell cycle GO:0051445 4 0.742
reciprocal dna recombination GO:0035825 4 0.725
nucleosome positioning GO:0016584 3 0.680
regulation of dna endoreduplication GO:0032875 5 0.657
chromosome condensation GO:0030261 15 0.639
meiotic nuclear division GO:0007126 10 0.597
Mouse
mitotic nuclear division GO:0007067 119 0.580
Yeast
regulation of cell cycle GO:0051726 393 0.534
circulatory system development GO:0072359 262 0.529
regulation of chromosome segregation GO:0051983 44 0.503
determination of adult lifespan GO:0008340 2 0.497
response to abiotic stimulus GO:0009628 336 0.493
nucleotide excision repair GO:0006289 31 0.474
mitotic cell cycle GO:0000278 326 0.461
dna recombination GO:0006310 77 0.447
recombinational repair GO:0000725 50 0.446
regulation of dna dependent dna replication GO:0090329 19 0.423
regulation of mitotic cell cycle phase transition GO:1901990 118 0.414
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.390
cardiovascular system development GO:0072358 262 0.368
negative regulation of cell proliferation GO:0008285 228 0.367
negative regulation of dna dependent dna replication GO:2000104 9 0.352
single organism cellular localization GO:1902580 332 0.333
mitotic cell cycle process GO:1903047 286 0.325
negative regulation of organelle organization GO:0010639 126 0.324
cellular amino acid metabolic process GO:0006520 116 0.311
meiosis i GO:0007127 4 0.307
cellular ketone metabolic process GO:0042180 80 0.305
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.305
nuclear division GO:0000280 128 0.304
Yeast Mouse
histone methylation GO:0016571 60 0.303
meiotic cell cycle GO:0051321 13 0.303
Mouse
negative regulation of dna metabolic process GO:0051053 57 0.293
post embryonic development GO:0009791 2 0.281
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.275
mitotic sister chromatid segregation GO:0000070 53 0.272
Yeast
regulation of sister chromatid cohesion GO:0007063 9 0.266
histone lysine methylation GO:0034968 50 0.260
dna methylation or demethylation GO:0044728 19 0.253
non recombinational repair GO:0000726 14 0.245
dna endoreduplication GO:0042023 5 0.238
heart development GO:0007507 95 0.232
genetic imprinting GO:0071514 1 0.228
regulation of dna replication GO:0006275 68 0.225
chromosome separation GO:0051304 23 0.222
double strand break repair via homologous recombination GO:0000724 50 0.218
atp catabolic process GO:0006200 157 0.213
g2 dna damage checkpoint GO:0031572 26 0.211
segmentation GO:0035282 4 0.208
reciprocal meiotic recombination GO:0007131 4 0.207
cell division GO:0051301 168 0.202
regulation of cell cycle g1 s phase transition GO:1902806 42 0.198
peptidyl lysine modification GO:0018205 144 0.197
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.192
cytokinesis completion of separation GO:0007109 3 0.188
tube development GO:0035295 125 0.184
embryo development ending in birth or egg hatching GO:0009792 34 0.181
Worm
amine metabolic process GO:0009308 44 0.177
purine nucleoside monophosphate metabolic process GO:0009126 186 0.164
base excision repair GO:0006284 21 0.163
g1 s transition of mitotic cell cycle GO:0000082 78 0.163
dna integrity checkpoint GO:0031570 71 0.158
rna dependent dna replication GO:0006278 16 0.158
reproductive system development GO:0061458 56 0.153
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.148
single organism reproductive process GO:0044702 98 0.144
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.144
negative regulation of cell differentiation GO:0045596 171 0.143
Mouse
peptidyl lysine acetylation GO:0018394 101 0.143
maintenance of dna repeat elements GO:0043570 4 0.142
regulation of cell cycle phase transition GO:1901987 126 0.142
cell part morphogenesis GO:0032990 137 0.141
Fly
cellular amine metabolic process GO:0044106 41 0.139
protein alkylation GO:0008213 74 0.135
embryo development GO:0009790 123 0.132
Worm
cell morphogenesis GO:0000902 296 0.131
Fly
regulation of cohesin localization to chromatin GO:0071922 4 0.130
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.129
multicellular organismal aging GO:0010259 3 0.128
histone acetylation GO:0016573 93 0.128
heart morphogenesis GO:0003007 48 0.122
oogenesis GO:0048477 2 0.118
positive regulation of catabolic process GO:0009896 310 0.116
regulation of mitotic cell cycle GO:0007346 189 0.113
histone h3 k4 methylation GO:0051568 27 0.109
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.109
protein localization to organelle GO:0033365 280 0.108
cellular component morphogenesis GO:0032989 314 0.107
Fly
regulation of cell cycle process GO:0010564 266 0.105
organelle localization GO:0051640 84 0.104
nucleoside triphosphate metabolic process GO:0009141 422 0.102
response to organic cyclic compound GO:0014070 204 0.102
lipid metabolic process GO:0006629 381 0.099
regulation of protein localization GO:0032880 296 0.098
meiotic cell cycle process GO:1903046 8 0.097
nucleotide catabolic process GO:0009166 408 0.096
organ morphogenesis GO:0009887 147 0.096
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.095
purine nucleoside triphosphate metabolic process GO:0009144 412 0.095
blastocyst development GO:0001824 3 0.095
leukocyte mediated immunity GO:0002443 59 0.095
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.095
internal protein amino acid acetylation GO:0006475 101 0.095
double strand break repair via nonhomologous end joining GO:0006303 10 0.094
cell projection organization GO:0030030 252 0.093
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.091
negative regulation of mitotic cell cycle GO:0045930 102 0.091
multicellular organismal homeostasis GO:0048871 67 0.090
neuron development GO:0048666 113 0.090
Fly
cell cycle arrest GO:0007050 71 0.089
nucleosome organization GO:0034728 66 0.088
meiotic chromosome separation GO:0051307 3 0.086
dna strand elongation involved in dna replication GO:0006271 3 0.086
development of primary sexual characteristics GO:0045137 35 0.084
Worm
microtubule based process GO:0007017 210 0.083
lymphocyte mediated immunity GO:0002449 48 0.081
nucleoside monophosphate catabolic process GO:0009125 159 0.081
negative regulation of cell death GO:0060548 345 0.080
ribonucleoside triphosphate catabolic process GO:0009203 391 0.078
histone modification GO:0016570 251 0.078
protein localization to chromosome GO:0034502 30 0.075
regulation of cellular amino acid metabolic process GO:0006521 6 0.074
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.074
generation of neurons GO:0048699 152 0.071
Fly
regulation of dna templated transcription initiation GO:2000142 9 0.070
protein acetylation GO:0006473 116 0.069
carbohydrate metabolic process GO:0005975 207 0.066
dna damage checkpoint GO:0000077 68 0.066
cell projection morphogenesis GO:0048858 129 0.065
Fly
regulation of transcription by chromatin organization GO:0034401 1 0.065
regulation of protein catabolic process GO:0042176 155 0.065
regulation of leukocyte activation GO:0002694 115 0.064
regulation of chromatin modification GO:1903308 51 0.064
reproductive process GO:0022414 106 0.064
Worm
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.062
positive regulation of cellular component organization GO:0051130 376 0.062
maintenance of location GO:0051235 112 0.061
regulation of mitotic sister chromatid separation GO:0010965 27 0.060
b cell activation GO:0042113 33 0.059
regulation of histone acetylation GO:0035065 19 0.059
vesicle mediated transport GO:0016192 371 0.058
Worm
positive regulation of immunoglobulin production GO:0002639 4 0.058
regionalization GO:0003002 29 0.058
organophosphate biosynthetic process GO:0090407 163 0.057
protein acylation GO:0043543 138 0.057
cell cycle g2 m phase transition GO:0044839 43 0.056
wnt signaling pathway GO:0016055 156 0.055
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.055
protein depolymerization GO:0051261 30 0.054
regulation of b cell activation GO:0050864 24 0.054
atp metabolic process GO:0046034 176 0.054
purine ribonucleoside catabolic process GO:0046130 398 0.053
cytokinesis GO:0000910 96 0.053
response to radiation GO:0009314 151 0.052
ribonucleoside monophosphate catabolic process GO:0009158 158 0.051
neuron projection morphogenesis GO:0048812 50 0.051
Fly
chromatin organization GO:0006325 351 0.051
positive regulation of cellular catabolic process GO:0031331 284 0.050
telomere organization GO:0032200 33 0.050
signal transduction in response to dna damage GO:0042770 57 0.050
membrane organization GO:0061024 292 0.050
positive regulation of isotype switching to iga isotypes GO:0048298 2 0.049
positive regulation of hydrolase activity GO:0051345 331 0.049
anatomical structure homeostasis GO:0060249 100 0.049
purine nucleoside monophosphate catabolic process GO:0009128 158 0.048
stem cell differentiation GO:0048863 93 0.047
Mouse
dna double strand break processing GO:0000729 10 0.047
negative regulation of protein maturation GO:1903318 142 0.047
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.046
positive regulation of protein phosphorylation GO:0001934 313 0.046
positive regulation of isotype switching GO:0045830 2 0.046
purine containing compound catabolic process GO:0072523 411 0.046
nervous system development GO:0007399 293 0.045
Fly
oocyte development GO:0048599 1 0.044
regulation of histone h3 k4 methylation GO:0051569 10 0.044
regulation of gene expression epigenetic GO:0040029 73 0.044
regulation of transferase activity GO:0051338 355 0.043
developmental process involved in reproduction GO:0003006 66 0.043
Worm
mitotic dna damage checkpoint GO:0044773 28 0.042
cell activation GO:0001775 213 0.042
female gamete generation GO:0007292 2 0.042
lipid biosynthetic process GO:0008610 177 0.041
ribonucleoside triphosphate metabolic process GO:0009199 412 0.041
regulation of lymphocyte activation GO:0051249 103 0.041
response to alcohol GO:0097305 64 0.040
endocytosis GO:0006897 159 0.040
Worm
organelle assembly GO:0070925 176 0.040
cell cycle g1 s phase transition GO:0044843 80 0.040
gonad development GO:0008406 34 0.040
Worm
positive regulation of proteolysis GO:0045862 142 0.039
hemopoiesis GO:0030097 180 0.039
regulation of immune response GO:0050776 201 0.038
isotype switching GO:0045190 3 0.038
chordate embryonic development GO:0043009 34 0.037
cytokinetic process GO:0032506 12 0.037
cell cycle checkpoint GO:0000075 117 0.037
negative regulation of developmental process GO:0051093 247 0.037
Mouse
dna alkylation GO:0006305 7 0.036
reproduction GO:0000003 63 0.036
Mouse Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.036
metaphase anaphase transition of cell cycle GO:0044784 21 0.036
phospholipid metabolic process GO:0006644 99 0.036
leukocyte activation GO:0045321 164 0.035
negative regulation of cell cycle phase transition GO:1901988 89 0.035
tissue homeostasis GO:0001894 63 0.035
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.035
protein maturation GO:0051604 233 0.035
regulation of kinase activity GO:0043549 314 0.035
interstrand cross link repair GO:0036297 3 0.034
ribonucleotide catabolic process GO:0009261 405 0.034
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.034
sensory organ morphogenesis GO:0090596 21 0.034
autophagic cell death GO:0048102 3 0.034
telomere capping GO:0016233 5 0.034
ubiquitin dependent protein catabolic process GO:0006511 206 0.033
somatic diversification of immunoglobulins GO:0016445 6 0.033
regulation of growth GO:0040008 165 0.033
dna duplex unwinding GO:0032508 30 0.032
negative regulation of protein metabolic process GO:0051248 391 0.032
circadian behavior GO:0048512 2 0.032
mitotic sister chromatid separation GO:0051306 18 0.032
regulation of wnt signaling pathway GO:0030111 123 0.031
macromolecular complex disassembly GO:0032984 60 0.031
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.031
apoptotic signaling pathway GO:0097190 268 0.031
double strand break repair via single strand annealing GO:0045002 4 0.031
somatic diversification of immune receptors GO:0002200 8 0.031
coenzyme metabolic process GO:0006732 65 0.031
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.031
nucleoside catabolic process GO:0009164 408 0.031
ras protein signal transduction GO:0007265 73 0.030
signal transduction involved in dna damage checkpoint GO:0072422 15 0.030
cellular lipid metabolic process GO:0044255 303 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
establishment of nucleus localization GO:0040023 1 0.030
cell cycle dna replication GO:0044786 11 0.030
positive regulation of cell cycle GO:0045787 140 0.030
response to inorganic substance GO:0010035 127 0.029
regulation of proteolysis GO:0030162 293 0.029
dna damage induced protein phosphorylation GO:0006975 5 0.029
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.029
myosin filament organization GO:0031033 2 0.028
activation of cysteine type endopeptidase activity GO:0097202 57 0.028
dna packaging GO:0006323 77 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
response to organonitrogen compound GO:0010243 156 0.028
pattern specification process GO:0007389 43 0.028
regulation of gene expression by genetic imprinting GO:0006349 1 0.027
regulation of isotype switching GO:0045191 2 0.027
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.027
system process GO:0003008 349 0.026
signal transduction by p53 class mediator GO:0072331 72 0.026
atrial septum primum morphogenesis GO:0003289 1 0.026
centrosome organization GO:0051297 58 0.026
cell activation involved in immune response GO:0002263 30 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
mismatch repair GO:0006298 15 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
adaptive immune response GO:0002250 49 0.025
v d j recombination GO:0033151 3 0.025
regulation of chromosome organization GO:0033044 103 0.025
negative regulation of protein processing GO:0010955 142 0.024
response to alkaloid GO:0043279 20 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
cellular modified amino acid metabolic process GO:0006575 64 0.024
monocarboxylic acid metabolic process GO:0032787 185 0.023
engulfment of apoptotic cell GO:0043652 2 0.023
cell development GO:0048468 328 0.023
Mouse Fly
dna synthesis involved in dna repair GO:0000731 6 0.023
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
positive regulation of protein catabolic process GO:0045732 75 0.022
regulation of cellular protein catabolic process GO:1903362 96 0.022
protein deubiquitination GO:0016579 79 0.022
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
regulation of mononuclear cell proliferation GO:0032944 65 0.022
regulation of protein processing GO:0070613 150 0.022
negative regulation of growth GO:0045926 97 0.021
small molecule biosynthetic process GO:0044283 157 0.021
regulation of response to dna damage stimulus GO:2001020 94 0.021
sex differentiation GO:0007548 45 0.021
Worm
positive regulation of cell proliferation GO:0008284 301 0.020
mononuclear cell proliferation GO:0032943 71 0.020
ribonucleoside monophosphate metabolic process GO:0009161 187 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
regulation of helicase activity GO:0051095 8 0.020
protein methylation GO:0006479 74 0.020
metencephalon development GO:0022037 2 0.020
positive regulation of leukocyte activation GO:0002696 80 0.020
skeletal system development GO:0001501 79 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.019
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.019
leukocyte activation involved in immune response GO:0002366 30 0.019
positive regulation of cell activation GO:0050867 81 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
production of molecular mediator of immune response GO:0002440 37 0.019
regulation of protein acetylation GO:1901983 25 0.019
central nervous system development GO:0007417 123 0.019
Fly
negative regulation of gluconeogenesis GO:0045721 2 0.019
positive regulation of lymphocyte activation GO:0051251 73 0.019
cellular response to abiotic stimulus GO:0071214 117 0.019
leukocyte proliferation GO:0070661 74 0.019
aging GO:0007568 66 0.019
nucleus localization GO:0051647 1 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
negative regulation of proteolysis GO:0045861 132 0.018
cellular homeostasis GO:0019725 196 0.018
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
telomere maintenance GO:0000723 32 0.018
regulation of mitosis GO:0007088 63 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.018
regulation of binding GO:0051098 111 0.018
g2 m transition of mitotic cell cycle GO:0000086 41 0.017
response to vitamin GO:0033273 13 0.017
maintenance of dna methylation GO:0010216 3 0.017
regulation of production of molecular mediator of immune response GO:0002700 25 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
single organism membrane organization GO:0044802 268 0.017
methylation GO:0032259 106 0.017
telomere maintenance via recombination GO:0000722 4 0.017
sensory organ development GO:0007423 52 0.017
nitrogen compound transport GO:0071705 191 0.017
metaphase plate congression GO:0051310 18 0.017
photoreceptor cell maintenance GO:0045494 13 0.017
negative regulation of meiotic cell cycle GO:0051447 2 0.017
response to activity GO:0014823 0 0.016
regulation of cell adhesion GO:0030155 166 0.016
response to ionizing radiation GO:0010212 65 0.016
Worm
negative regulation of peptidase activity GO:0010466 91 0.016
regulation of cellular component movement GO:0051270 334 0.016
regulation of protein kinase activity GO:0045859 289 0.016
zymogen activation GO:0031638 70 0.016
negative regulation of chromosome segregation GO:0051985 18 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
myeloid cell differentiation GO:0030099 117 0.016
positive regulation of mitotic cell cycle GO:0045931 60 0.016
protein catabolic process GO:0030163 325 0.016
regulation of protein maturation GO:1903317 150 0.016
positive regulation of developmental process GO:0051094 314 0.015
septum secundum development GO:0003285 2 0.015
protein complex disassembly GO:0043241 52 0.015
response to nutrient levels GO:0031667 81 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
monosaccharide metabolic process GO:0005996 74 0.015
cofactor metabolic process GO:0051186 87 0.015
regeneration GO:0031099 4 0.015
regulation of microtubule polymerization GO:0031113 12 0.015
myosin filament assembly GO:0031034 2 0.015
response to gamma radiation GO:0010332 14 0.015
establishment of organelle localization GO:0051656 59 0.015
negative regulation of sister chromatid segregation GO:0033046 17 0.015
negative regulation of phosphorylation GO:0042326 174 0.014
glycerolipid metabolic process GO:0046486 107 0.014
maintenance of protein location in cell GO:0032507 56 0.014
hematopoietic stem cell differentiation GO:0060218 4 0.014
positive regulation of immune system process GO:0002684 283 0.014
b cell proliferation GO:0042100 22 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
maintenance of sister chromatid cohesion GO:0034086 6 0.014
hindbrain development GO:0030902 3 0.014
positive regulation of transferase activity GO:0051347 227 0.014
leading strand elongation GO:0006272 1 0.014
immune effector process GO:0002252 159 0.014
muscle cell differentiation GO:0042692 63 0.014
maintenance of location in cell GO:0051651 62 0.014
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 10 0.014
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.014
neuron death GO:0070997 65 0.013
dna replication dependent nucleosome assembly GO:0006335 32 0.013
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.013
head development GO:0060322 108 0.013
Fly
positive regulation of cellular protein catabolic process GO:1903364 37 0.013
regulation of protein transport GO:0051223 213 0.013
positive regulation of peptidase activity GO:0010952 88 0.013
protein processing GO:0016485 226 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
microtubule anchoring GO:0034453 24 0.013
response to transforming growth factor beta GO:0071559 94 0.013
regulation of cellular response to stress GO:0080135 244 0.013
neuron projection development GO:0031175 106 0.013
Fly
dna methylation GO:0006306 7 0.013
regulation of microtubule based process GO:0032886 74 0.013
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.013
cell aging GO:0007569 52 0.013
positive regulation of immune response GO:0050778 159 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
rostrocaudal neural tube patterning GO:0021903 1 0.012
oocyte differentiation GO:0009994 2 0.012
male gonad development GO:0008584 23 0.012
generation of precursor metabolites and energy GO:0006091 68 0.012
regulation of myeloid cell differentiation GO:0045637 81 0.012
adult locomotory behavior GO:0008344 1 0.012
thymus development GO:0048538 3 0.012
response to other organism GO:0051707 261 0.012
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 3 0.012
negative regulation of meiosis GO:0045835 1 0.012
receptor mediated endocytosis GO:0006898 84 0.012
Worm
response to drug GO:0042493 81 0.012
autophagy GO:0006914 88 0.012
mitotic dna integrity checkpoint GO:0044774 30 0.012
dna modification GO:0006304 27 0.012
negative regulation of glial cell apoptotic process GO:0034351 6 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
protein k63 linked deubiquitination GO:0070536 21 0.012
dna biosynthetic process GO:0071897 40 0.012
response to endoplasmic reticulum stress GO:0034976 49 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
glycerophospholipid biosynthetic process GO:0046474 40 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
digestive tract morphogenesis GO:0048546 56 0.011
actin filament based process GO:0030029 224 0.011
response to oxygen levels GO:0070482 100 0.011
dna conformation change GO:0071103 113 0.011
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.011
regulation of peptidyl lysine acetylation GO:2000756 22 0.011
spermatid development GO:0007286 4 0.011
cellular response to decreased oxygen levels GO:0036294 51 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
intra s dna damage checkpoint GO:0031573 4 0.011
positive regulation of cell cycle arrest GO:0071158 23 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
positive regulation of meiotic cell cycle GO:0051446 2 0.011
negative regulation of epithelial cell proliferation GO:0050680 48 0.011
maintenance of protein location GO:0045185 57 0.011
negative regulation of cellular protein catabolic process GO:1903363 38 0.011
response to bacterium GO:0009617 144 0.011
response to nitrogen compound GO:1901698 184 0.011
dna replication initiation GO:0006270 6 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
cytoplasmic transport GO:0016482 379 0.010
regulation of b cell mediated immunity GO:0002712 7 0.010
regulation of intracellular transport GO:0032386 195 0.010
attachment of spindle microtubules to kinetochore GO:0008608 17 0.010
g1 dna damage checkpoint GO:0044783 18 0.010
resolution of meiotic recombination intermediates GO:0000712 3 0.010
tube morphogenesis GO:0035239 95 0.010
regulation of double strand break repair GO:2000779 22 0.010
sister chromatid biorientation GO:0031134 2 0.010
reproductive structure development GO:0048608 55 0.010
Worm
dna unwinding involved in dna replication GO:0006268 2 0.010
sulfur compound metabolic process GO:0006790 101 0.010

SMC1A disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.384
cancer DOID:162 167 0.167
organ system cancer DOID:0050686 164 0.094
dementia DOID:1307 19 0.067
disease of mental health DOID:150 70 0.067
cognitive disorder DOID:1561 29 0.067
immune system cancer DOID:0060083 36 0.030
hematologic cancer DOID:2531 36 0.030
thoracic cancer DOID:5093 21 0.016
reproductive organ cancer DOID:193 23 0.015
immune system disease DOID:2914 155 0.014
female reproductive organ cancer DOID:120 10 0.013
disease of metabolism DOID:0014667 295 0.013
inherited metabolic disorder DOID:655 242 0.013
musculoskeletal system cancer DOID:0060100 11 0.010
connective tissue cancer DOID:201 7 0.010
cornelia de lange syndrome DOID:11725 5 0.001