Homo sapiens

38 known processes

SMC4

structural maintenance of chromosomes 4

(Aliases: SMC4L1,hCAP-C,CAPC)

SMC4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleoside monophosphate catabolic process GO:0009158 158 0.984
regulation of meiotic cell cycle GO:0051445 4 0.982
meiotic chromosome segregation GO:0045132 4 0.980
Mouse
dna packaging GO:0006323 77 0.980
nuclear division GO:0000280 128 0.968
mitotic sister chromatid segregation GO:0000070 53 0.935
microtubule cytoskeleton organization GO:0000226 176 0.933
Fly
mitotic nuclear division GO:0007067 119 0.929
dna conformation change GO:0071103 113 0.927
mitotic chromosome condensation GO:0007076 11 0.925
regulation of meiosis GO:0040020 3 0.922
mitotic cell cycle process GO:1903047 286 0.919
organelle fission GO:0048285 149 0.915
ribonucleotide catabolic process GO:0009261 405 0.915
mitotic cell cycle GO:0000278 326 0.907
nucleoside monophosphate catabolic process GO:0009125 159 0.906
purine nucleoside monophosphate metabolic process GO:0009126 186 0.895
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.870
regulation of cell cycle GO:0051726 393 0.862
atp metabolic process GO:0046034 176 0.831
regulation of cell cycle process GO:0010564 266 0.829
atp catabolic process GO:0006200 157 0.805
chromosome segregation GO:0007059 114 0.796
nucleoside catabolic process GO:0009164 408 0.762
regulation of nuclear division GO:0051783 65 0.749
negative regulation of meiotic cell cycle GO:0051447 2 0.730
negative regulation of organelle organization GO:0010639 126 0.711
ribonucleoside catabolic process GO:0042454 406 0.704
purine containing compound catabolic process GO:0072523 411 0.697
meiosis i GO:0007127 4 0.678
purine nucleoside monophosphate catabolic process GO:0009128 158 0.669
spindle organization GO:0007051 53 0.621
Fly
microtubule based process GO:0007017 210 0.604
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.601
negative regulation of cellular component organization GO:0051129 235 0.601
post embryonic development GO:0009791 2 0.598
Worm
purine nucleoside catabolic process GO:0006152 398 0.593
negative regulation of meiosis GO:0045835 1 0.588
negative regulation of cell cycle process GO:0010948 121 0.575
nucleotide catabolic process GO:0009166 408 0.573
negative regulation of cell cycle GO:0045786 193 0.568
purine nucleoside triphosphate catabolic process GO:0009146 392 0.542
regulation of cell division GO:0051302 116 0.536
chromosome separation GO:0051304 23 0.500
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.495
purine ribonucleotide catabolic process GO:0009154 404 0.493
cell division GO:0051301 168 0.492
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.423
purine ribonucleoside metabolic process GO:0046128 437 0.379
sister chromatid segregation GO:0000819 54 0.374
embryo development GO:0009790 123 0.369
Worm
regulation of mitotic cell cycle GO:0007346 189 0.357
nucleoside triphosphate metabolic process GO:0009141 422 0.356
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.353
purine ribonucleoside catabolic process GO:0046130 398 0.340
blastocyst development GO:0001824 3 0.323
mitotic sister chromatid separation GO:0051306 18 0.322
purine nucleotide catabolic process GO:0006195 405 0.312
regulation of dna metabolic process GO:0051052 153 0.310
positive regulation of cellular component organization GO:0051130 376 0.300
glycosyl compound catabolic process GO:1901658 413 0.288
ribonucleoside triphosphate catabolic process GO:0009203 391 0.287
nucleoside monophosphate metabolic process GO:0009123 191 0.270
dna replication GO:0006260 116 0.256
nucleoside triphosphate catabolic process GO:0009143 394 0.254
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.238
nucleoside phosphate catabolic process GO:1901292 412 0.238
regulation of mitotic sister chromatid segregation GO:0033047 27 0.237
negative regulation of mitotic cell cycle GO:0045930 102 0.236
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.234
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.220
organophosphate catabolic process GO:0046434 430 0.210
nervous system development GO:0007399 293 0.205
Worm
negative regulation of cell division GO:0051782 31 0.197
meiotic nuclear division GO:0007126 10 0.196
Mouse
chromosome condensation GO:0030261 15 0.193
spindle assembly involved in mitosis GO:0090307 12 0.193
cellular response to dna damage stimulus GO:0006974 379 0.187
single organism cellular localization GO:1902580 332 0.183
regulation of microtubule cytoskeleton organization GO:0070507 61 0.179
ribosomal small subunit export from nucleus GO:0000056 3 0.163
regulation of gene expression epigenetic GO:0040029 73 0.160
Worm
spindle elongation GO:0051231 4 0.150
regulation of mitotic cell cycle phase transition GO:1901990 118 0.144
dosage compensation GO:0007549 3 0.143
Worm
chromatin modification GO:0016568 298 0.137
gene silencing GO:0016458 49 0.131
mitotic spindle organization GO:0007052 27 0.130
Fly
regulation of cytoskeleton organization GO:0051493 177 0.128
dna dependent dna replication GO:0006261 44 0.125
positive regulation of catabolic process GO:0009896 310 0.122
microtubule organizing center organization GO:0031023 62 0.120
positive regulation of organelle organization GO:0010638 195 0.118
regulation of cell cycle phase transition GO:1901987 126 0.110
ribonucleoside monophosphate metabolic process GO:0009161 187 0.109
golgi organization GO:0007030 38 0.097
regulation of response to dna damage stimulus GO:2001020 94 0.095
tube development GO:0035295 125 0.095
neurogenesis GO:0022008 169 0.093
Worm
protein depolymerization GO:0051261 30 0.092
meiotic cell cycle process GO:1903046 8 0.092
Mouse
sex differentiation GO:0007548 45 0.089
Worm
maintenance of location GO:0051235 112 0.088
regulation of microtubule based process GO:0032886 74 0.086
cellular component disassembly GO:0022411 92 0.086
regulation of cellular response to stress GO:0080135 244 0.084
protein localization to organelle GO:0033365 280 0.084
enzyme linked receptor protein signaling pathway GO:0007167 303 0.081
regulation of nucleotide metabolic process GO:0006140 269 0.074
negative regulation of cellular protein metabolic process GO:0032269 353 0.074
protein maturation GO:0051604 233 0.073
reproductive system development GO:0061458 56 0.072
Worm
reproduction GO:0000003 63 0.071
Mouse Worm
response to nitrogen compound GO:1901698 184 0.070
cell cycle phase transition GO:0044770 173 0.070
neuroblast proliferation GO:0007405 4 0.069
negative regulation of protein maturation GO:1903318 142 0.068
centrosome organization GO:0051297 58 0.065
ribonucleoside triphosphate metabolic process GO:0009199 412 0.065
organelle assembly GO:0070925 176 0.065
regulation of cellular component biogenesis GO:0044087 281 0.063
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.062
protein catabolic process GO:0030163 325 0.062
negative regulation of chromosome organization GO:2001251 48 0.062
regulation of nucleoside metabolic process GO:0009118 209 0.061
female gamete generation GO:0007292 2 0.061
chromatin organization GO:0006325 351 0.060
development of primary sexual characteristics GO:0045137 35 0.060
Worm
cellular response to oxygen containing compound GO:1901701 276 0.060
positive regulation of cell cycle GO:0045787 140 0.060
cell cycle checkpoint GO:0000075 117 0.059
oxidation reduction process GO:0055114 396 0.059
generation of neurons GO:0048699 152 0.056
Worm
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.055
positive regulation of protein transport GO:0051222 135 0.053
apoptotic signaling pathway GO:0097190 268 0.053
positive regulation of cell death GO:0010942 263 0.052
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.052
gonad development GO:0008406 34 0.051
Worm
regulation of kinase activity GO:0043549 314 0.051
single organism reproductive process GO:0044702 98 0.050
Worm
cellular component morphogenesis GO:0032989 314 0.049
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.049
negative regulation of proteolysis GO:0045861 132 0.048
intracellular protein transport GO:0006886 270 0.047
ubiquitin dependent protein catabolic process GO:0006511 206 0.047
modification dependent macromolecule catabolic process GO:0043632 212 0.047
regulation of cell differentiation GO:0045595 393 0.047
regulation of dna repair GO:0006282 47 0.047
nucleocytoplasmic transport GO:0006913 176 0.046
negative regulation of protein processing GO:0010955 142 0.046
cellular protein catabolic process GO:0044257 261 0.045
cellular macromolecule catabolic process GO:0044265 380 0.045
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.044
negative regulation of protein metabolic process GO:0051248 391 0.043
centrosome cycle GO:0007098 32 0.042
posttranscriptional regulation of gene expression GO:0010608 213 0.042
microtubule polymerization or depolymerization GO:0031109 37 0.042
negative regulation of protein catabolic process GO:0042177 59 0.041
regulation of transferase activity GO:0051338 355 0.041
cellular macromolecular complex assembly GO:0034622 324 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.041
positive regulation of nucleotide metabolic process GO:0045981 230 0.040
regulation of chromosome segregation GO:0051983 44 0.040
microtubule depolymerization GO:0007019 18 0.040
asymmetric neuroblast division GO:0055059 1 0.040
regeneration GO:0031099 4 0.039
response to abiotic stimulus GO:0009628 336 0.039
positive regulation of nucleotide catabolic process GO:0030813 185 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
positive regulation of hydrolase activity GO:0051345 331 0.037
cellular protein complex assembly GO:0043623 188 0.037
centrosome duplication GO:0051298 28 0.036
mrna metabolic process GO:0016071 175 0.036
cellular response to endogenous stimulus GO:0071495 336 0.036
endomembrane system organization GO:0010256 196 0.036
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.034
oogenesis GO:0048477 2 0.033
ribosome assembly GO:0042255 9 0.033
regulation of protein localization GO:0032880 296 0.033
regulation of proteolysis GO:0030162 293 0.032
positive regulation of apoptotic process GO:0043065 246 0.031
positive regulation of programmed cell death GO:0043068 249 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
protein processing GO:0016485 226 0.031
protein oligomerization GO:0051259 173 0.031
negative regulation of cell cycle phase transition GO:1901988 89 0.031
negative regulation of cellular protein catabolic process GO:1903363 38 0.030
regulation of chromosome organization GO:0033044 103 0.030
mitotic cell cycle phase transition GO:0044772 162 0.029
chordate embryonic development GO:0043009 34 0.029
regulation of protein processing GO:0070613 150 0.029
mitotic spindle elongation GO:0000022 4 0.028
cellular protein complex disassembly GO:0043624 36 0.028
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.028
intrinsic apoptotic signaling pathway GO:0097193 127 0.028
cellular response to hormone stimulus GO:0032870 125 0.028
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.028
establishment of organelle localization GO:0051656 59 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
positive regulation of cell development GO:0010720 92 0.026
mitotic spindle checkpoint GO:0071174 18 0.026
negative regulation of developmental process GO:0051093 247 0.026
negative regulation of cell death GO:0060548 345 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
positive regulation of cell cycle process GO:0090068 106 0.026
cell development GO:0048468 328 0.025
Worm
negative regulation of cell differentiation GO:0045596 171 0.025
regulation of protein maturation GO:1903317 150 0.025
growth GO:0040007 202 0.025
protein complex disassembly GO:0043241 52 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
epithelium development GO:0060429 227 0.024
regulation of dna replication GO:0006275 68 0.024
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.023
rna interference GO:0016246 4 0.023
regulation of proteasomal protein catabolic process GO:0061136 87 0.023
regulation of nucleocytoplasmic transport GO:0046822 98 0.023
actin cytoskeleton organization GO:0030036 207 0.023
cell morphogenesis GO:0000902 296 0.022
positive regulation of protein phosphorylation GO:0001934 313 0.022
dna repair GO:0006281 198 0.022
ras protein signal transduction GO:0007265 73 0.022
mitotic cell cycle checkpoint GO:0007093 68 0.022
spermatid development GO:0007286 4 0.022
regulation of mitosis GO:0007088 63 0.021
regulation of sister chromatid segregation GO:0033045 27 0.021
response to hormone GO:0009725 175 0.021
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.021
kinetochore organization GO:0051383 8 0.021
Mouse
attachment of spindle microtubules to kinetochore GO:0008608 17 0.020
meiotic cell cycle GO:0051321 13 0.020
Mouse
positive regulation of phosphorylation GO:0042327 394 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
positive regulation of intracellular protein transport GO:0090316 76 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
cellular amine metabolic process GO:0044106 41 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
reproductive process GO:0022414 106 0.019
Worm
double strand break repair GO:0006302 101 0.019
sister chromatid biorientation GO:0031134 2 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
regulation of mitotic sister chromatid separation GO:0010965 27 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
regulation of protein kinase activity GO:0045859 289 0.019
viral process GO:0016032 146 0.019
protein polymerization GO:0051258 71 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
digestive tract morphogenesis GO:0048546 56 0.018
nuclear import GO:0051170 106 0.018
positive regulation of mitotic cell cycle GO:0045931 60 0.018
macromolecular complex disassembly GO:0032984 60 0.018
mitotic spindle assembly checkpoint GO:0007094 14 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
negative regulation of gene expression epigenetic GO:0045814 19 0.017
peptidyl serine phosphorylation GO:0018105 101 0.017
positive regulation of wnt signaling pathway GO:0030177 54 0.017
regulation of growth GO:0040008 165 0.017
response to light stimulus GO:0009416 87 0.017
regulation of protein complex assembly GO:0043254 147 0.017
stem cell differentiation GO:0048863 93 0.017
regulation of protein transport GO:0051223 213 0.016
positive regulation of transferase activity GO:0051347 227 0.016
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.016
embryo development ending in birth or egg hatching GO:0009792 34 0.016
Worm
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
negative regulation of cellular catabolic process GO:0031330 83 0.016
reproductive structure development GO:0048608 55 0.016
Worm
chromatin remodeling GO:0006338 55 0.016
organelle localization GO:0051640 84 0.016
regulation of mitotic spindle organization GO:0060236 6 0.016
peptidyl serine modification GO:0018209 106 0.016
regulation of chromatin modification GO:1903308 51 0.016
amine metabolic process GO:0009308 44 0.016
positive regulation of chromosome organization GO:2001252 41 0.016
cytoplasmic transport GO:0016482 379 0.016
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.015
anatomical structure homeostasis GO:0060249 100 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
actin filament based process GO:0030029 224 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
protein targeting GO:0006605 187 0.015
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.015
positive regulation of proteolysis GO:0045862 142 0.015
cellular response to oxidative stress GO:0034599 85 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
regulation of cell morphogenesis GO:0022604 153 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.014
cell part morphogenesis GO:0032990 137 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
regulation of locomotion GO:0040012 329 0.014
developmental growth GO:0048589 48 0.014
interspecies interaction between organisms GO:0044419 156 0.013
negative regulation of catabolic process GO:0009895 104 0.013
regulation of protein catabolic process GO:0042176 155 0.013
behavior GO:0007610 112 0.013
Worm
regulation of chromatin assembly or disassembly GO:0001672 6 0.013
activation of cysteine type endopeptidase activity GO:0097202 57 0.013
positive regulation of cell proliferation GO:0008284 301 0.012
protein targeting to nucleus GO:0044744 104 0.012
cell projection organization GO:0030030 252 0.012
Worm
receptor mediated endocytosis GO:0006898 84 0.012
regulation of viral process GO:0050792 103 0.012
cellular ketone metabolic process GO:0042180 80 0.012
regulation of dendritic cell chemotaxis GO:2000508 4 0.012
nucleus localization GO:0051647 1 0.012
negative regulation of chromosome segregation GO:0051985 18 0.012
response to oxidative stress GO:0006979 121 0.012
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902165 7 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
multicellular organism reproduction GO:0032504 42 0.012
Worm
regulation of cell development GO:0060284 161 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
cellular amino acid metabolic process GO:0006520 116 0.011
negative regulation of dna metabolic process GO:0051053 57 0.011
hemopoiesis GO:0030097 180 0.011
positive regulation of mitosis GO:0045840 25 0.011
regulation of double strand break repair GO:2000779 22 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
zymogen activation GO:0031638 70 0.011
regulation of neurogenesis GO:0050767 82 0.011
maintenance of location in cell GO:0051651 62 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.011
g2 m transition of mitotic cell cycle GO:0000086 41 0.011
mature ribosome assembly GO:0042256 5 0.011
response to caffeine GO:0031000 3 0.011
histone exchange GO:0043486 3 0.011
negative regulation of sister chromatid segregation GO:0033046 17 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
protein import GO:0017038 130 0.011
regulation of intracellular transport GO:0032386 195 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
nuclear transport GO:0051169 179 0.010
oocyte development GO:0048599 1 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.010
metaphase anaphase transition of cell cycle GO:0044784 21 0.010
positive regulation of nervous system development GO:0051962 54 0.010
cell cycle arrest GO:0007050 71 0.010
chromatin silencing GO:0006342 12 0.010
maintenance of protein location in cell GO:0032507 56 0.010
mitotic dna integrity checkpoint GO:0044774 30 0.010
central nervous system development GO:0007417 123 0.010
regulation of peptidase activity GO:0052547 180 0.010
viral life cycle GO:0019058 132 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010

SMC4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.027
immune system disease DOID:2914 155 0.012
cancer DOID:162 167 0.010