Homo sapiens

67 known processes

SMCR7L

Smith-Magenis syndrome chromosome region, candidate 7-like

(Aliases: HSU79252,FLJ20232,dJ1104E15.3)

SMCR7L biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.638
release of cytochrome c from mitochondria GO:0001836 35 0.623
positive regulation of mitochondrion organization GO:0010822 30 0.582
peroxisome organization GO:0007031 28 0.510
positive regulation of protein targeting to membrane GO:0090314 8 0.472
mitochondrion organization GO:0007005 156 0.375
regulation of apoptotic signaling pathway GO:2001233 175 0.331
mitochondrial calcium ion homeostasis GO:0051560 11 0.329
gtp metabolic process GO:0046039 239 0.320
purine nucleotide catabolic process GO:0006195 405 0.315
apoptotic mitochondrial changes GO:0008637 57 0.291
nucleoside triphosphate catabolic process GO:0009143 394 0.290
membrane fusion GO:0061025 43 0.287
regulation of protein localization GO:0032880 296 0.287
positive regulation of apoptotic signaling pathway GO:2001235 70 0.257
protein homooligomerization GO:0051260 100 0.255
multicellular organismal aging GO:0010259 3 0.253
protein localization to mitochondrion GO:0070585 25 0.251
regulation of protein transport GO:0051223 213 0.249
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.246
cellular component morphogenesis GO:0032989 314 0.238
apoptotic signaling pathway GO:0097190 268 0.220
ribonucleotide catabolic process GO:0009261 405 0.217
guanosine containing compound catabolic process GO:1901069 239 0.214
protein localization to organelle GO:0033365 280 0.211
mitochondrial fission GO:0000266 14 0.210
gtp catabolic process GO:0006184 237 0.209
guanosine containing compound metabolic process GO:1901068 244 0.204
mitochondrial fragmentation involved in apoptotic process GO:0043653 7 0.204
positive regulation of protein transport GO:0051222 135 0.202
positive regulation of programmed cell death GO:0043068 249 0.184
positive regulation of cell death GO:0010942 263 0.175
single organism membrane organization GO:0044802 268 0.174
purine ribonucleoside metabolic process GO:0046128 437 0.172
purine containing compound catabolic process GO:0072523 411 0.164
regulation of protein targeting GO:1903533 91 0.158
regulation of cellular component biogenesis GO:0044087 281 0.153
positive regulation of cellular component organization GO:0051130 376 0.153
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.147
organic anion transport GO:0015711 103 0.146
purine nucleoside triphosphate catabolic process GO:0009146 392 0.146
peroxisome fission GO:0016559 10 0.146
determination of adult lifespan GO:0008340 2 0.145
nucleoside catabolic process GO:0009164 408 0.140
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.140
ribonucleoside catabolic process GO:0042454 406 0.140
regulation of mitochondrial fission GO:0090140 8 0.133
intracellular protein transport GO:0006886 270 0.131
regulation of intracellular transport GO:0032386 195 0.127
cellular macromolecular complex assembly GO:0034622 324 0.125
positive regulation of transport GO:0051050 336 0.119
positive regulation of apoptotic process GO:0043065 246 0.116
mitochondrion morphogenesis GO:0070584 8 0.110
regulation of protein complex assembly GO:0043254 147 0.108
vesicle mediated transport GO:0016192 371 0.104
single organism membrane fusion GO:0044801 37 0.100
membrane organization GO:0061024 292 0.096
cytoplasmic transport GO:0016482 379 0.094
ribonucleoside triphosphate catabolic process GO:0009203 391 0.092
secretion GO:0046903 254 0.090
intrinsic apoptotic signaling pathway GO:0097193 127 0.089
ribonucleoside triphosphate metabolic process GO:0009199 412 0.089
cellular protein complex assembly GO:0043623 188 0.089
glycosyl compound catabolic process GO:1901658 413 0.088
positive regulation of organelle organization GO:0010638 195 0.087
establishment of protein localization to mitochondrion GO:0072655 22 0.086
regulation of intracellular protein transport GO:0033157 123 0.083
nucleoside triphosphate metabolic process GO:0009141 422 0.081
positive regulation of intracellular transport GO:0032388 104 0.080
purine ribonucleotide catabolic process GO:0009154 404 0.078
protein oligomerization GO:0051259 173 0.075
regulation of mitochondrion organization GO:0010821 54 0.073
establishment of protein localization to organelle GO:0072594 172 0.073
purine ribonucleoside catabolic process GO:0046130 398 0.071
organophosphate catabolic process GO:0046434 430 0.070
purine nucleoside catabolic process GO:0006152 398 0.069
nucleotide catabolic process GO:0009166 408 0.067
protein targeting GO:0006605 187 0.065
regulation of secretion by cell GO:1903530 177 0.064
positive regulation of intracellular protein transport GO:0090316 76 0.063
positive regulation of mitochondrial calcium ion concentration GO:0051561 8 0.063
regulation of establishment of protein localization GO:0070201 242 0.061
purine nucleoside triphosphate metabolic process GO:0009144 412 0.060
positive regulation of mitochondrial fission GO:0090141 7 0.054
calcium ion homeostasis GO:0055074 122 0.051
second messenger mediated signaling GO:0019932 78 0.051
negative regulation of cellular component organization GO:0051129 235 0.050
neuromuscular junction development GO:0007528 3 0.049
protein polymerization GO:0051258 71 0.048
secretion by cell GO:0032940 226 0.045
small gtpase mediated signal transduction GO:0007264 78 0.042
cellular homeostasis GO:0019725 196 0.042
nucleoside phosphate catabolic process GO:1901292 412 0.041
protein import into nucleus GO:0006606 104 0.041
regulation of anatomical structure morphogenesis GO:0022603 286 0.040
divalent inorganic cation homeostasis GO:0072507 136 0.040
protein secretion GO:0009306 98 0.040
cell part morphogenesis GO:0032990 137 0.038
regulation of secretion GO:0051046 194 0.036
regulation of locomotion GO:0040012 329 0.036
regulation of translation GO:0006417 89 0.036
regulation of protein secretion GO:0050708 86 0.035
autophagy GO:0006914 88 0.034
negative regulation of phosphate metabolic process GO:0045936 267 0.034
cellular amino acid metabolic process GO:0006520 116 0.034
protein processing GO:0016485 226 0.033
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 6 0.033
post embryonic development GO:0009791 2 0.032
mitochondrial transport GO:0006839 60 0.032
aging GO:0007568 66 0.031
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.031
ion homeostasis GO:0050801 230 0.030
protein maturation GO:0051604 233 0.030
negative regulation of developmental process GO:0051093 247 0.030
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.030
regulation of endopeptidase activity GO:0052548 170 0.030
cellular metal ion homeostasis GO:0006875 146 0.029
protein ubiquitination GO:0016567 314 0.029
cellular calcium ion homeostasis GO:0006874 117 0.029
cellular cation homeostasis GO:0030003 163 0.028
ras protein signal transduction GO:0007265 73 0.028
protein targeting to membrane GO:0006612 42 0.027
metal ion homeostasis GO:0055065 169 0.027
calcium mediated signaling GO:0019722 44 0.026
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.026
protein homotetramerization GO:0051289 28 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.024
positive regulation of secretion by cell GO:1903532 108 0.024
negative regulation of protein modification process GO:0031400 200 0.024
regulation of cellular component movement GO:0051270 334 0.024
endosomal transport GO:0016197 129 0.024
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.024
negative regulation of protein metabolic process GO:0051248 391 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
negative regulation of multicellular organismal process GO:0051241 317 0.023
cellular chemical homeostasis GO:0055082 180 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
biological adhesion GO:0022610 331 0.022
regulation of transferase activity GO:0051338 355 0.022
protein import GO:0017038 130 0.022
cellular divalent inorganic cation homeostasis GO:0072503 128 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
negative regulation of catalytic activity GO:0043086 335 0.021
cell adhesion GO:0007155 325 0.021
anion transport GO:0006820 161 0.021
protein tetramerization GO:0051262 47 0.021
response to oxygen containing compound GO:1901700 369 0.021
cellular ketone metabolic process GO:0042180 80 0.020
regulation of cytoplasmic transport GO:1903649 149 0.020
cellular protein catabolic process GO:0044257 261 0.019
single organism cellular localization GO:1902580 332 0.019
regulation of protein kinase activity GO:0045859 289 0.019
cellular response to nitrogen compound GO:1901699 144 0.019
cellular ion homeostasis GO:0006873 168 0.019
positive regulation of secretion GO:0051047 116 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
protein localization to membrane GO:0072657 160 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.018
necrotic cell death GO:0070265 21 0.017
positive regulation of proteolysis GO:0045862 142 0.017
cell morphogenesis GO:0000902 296 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
positive regulation of peptidase activity GO:0010952 88 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
chemical homeostasis GO:0048878 306 0.017
endocytosis GO:0006897 159 0.017
regulation of protein oligomerization GO:0032459 26 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
protein catabolic process GO:0030163 325 0.017
cation homeostasis GO:0055080 189 0.017
regulation of cytokine production GO:0001817 232 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
cell aging GO:0007569 52 0.016
regulation of protein maturation GO:1903317 150 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
regulation of gtpase activity GO:0043087 180 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
amine metabolic process GO:0009308 44 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
ncrna processing GO:0034470 83 0.015
rna processing GO:0006396 255 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
regulation of cell motility GO:2000145 299 0.015
chronological cell aging GO:0001300 2 0.015
negative regulation of phosphorylation GO:0042326 174 0.014
regulation of cell migration GO:0030334 289 0.014
regulation of cellular response to stress GO:0080135 244 0.014
system process GO:0003008 349 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
receptor mediated endocytosis GO:0006898 84 0.014
negative regulation of growth GO:0045926 97 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
oogenesis GO:0048477 2 0.014
lipid metabolic process GO:0006629 381 0.014
transmembrane transport GO:0055085 399 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.014
cell growth GO:0016049 160 0.014
negative regulation of cell death GO:0060548 345 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
positive regulation of catabolic process GO:0009896 310 0.013
regulation of peptidase activity GO:0052547 180 0.013
cerebral cortex radially oriented cell migration GO:0021799 1 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
negative regulation of locomotion GO:0040013 118 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
dephosphorylation GO:0016311 209 0.012
rho protein signal transduction GO:0007266 26 0.012
cell projection morphogenesis GO:0048858 129 0.012
regulation of protein catabolic process GO:0042176 155 0.012
regulation of defense response GO:0031347 154 0.012
substrate adhesion dependent cell spreading GO:0034446 41 0.012
programmed necrotic cell death GO:0097300 18 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
negative regulation of catabolic process GO:0009895 104 0.012
nervous system development GO:0007399 293 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
negative regulation of proteolysis GO:0045861 132 0.012
positive regulation of protein secretion GO:0050714 60 0.012
maturation of ssu rrna GO:0030490 3 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
locomotory behavior GO:0007626 1 0.012
mitotic cell cycle GO:0000278 326 0.012
mitotic sister chromatid segregation GO:0000070 53 0.012
regulation of nervous system development GO:0051960 88 0.012
single organism reproductive process GO:0044702 98 0.012
cell substrate adhesion GO:0031589 132 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
negative regulation of kinase activity GO:0033673 106 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
cation transport GO:0006812 331 0.011
negative regulation of cell development GO:0010721 48 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
immune response GO:0006955 307 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
regulation of rna splicing GO:0043484 62 0.011
organophosphate ester transport GO:0015748 32 0.011
protein targeting to nucleus GO:0044744 104 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
memory GO:0007613 3 0.011
translation GO:0006412 132 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
nuclear transport GO:0051169 179 0.011
regulation of cell growth GO:0001558 135 0.011
cell development GO:0048468 328 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
nerve development GO:0021675 4 0.010
organelle assembly GO:0070925 176 0.010
response to abiotic stimulus GO:0009628 336 0.010
regulation of cellular ketone metabolic process GO:0010565 50 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
tissue regeneration GO:0042246 3 0.010

SMCR7L disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015
disease of metabolism DOID:0014667 295 0.015
retinal disease DOID:5679 118 0.011
retinal degeneration DOID:8466 89 0.011
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011
central nervous system disease DOID:331 186 0.011