Homo sapiens

126 known processes

SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

(Aliases: ASMASE,NPD,ASM)

SMPD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of digestive system process GO:0060456 2 0.872
protein processing GO:0016485 226 0.806
protein maturation GO:0051604 233 0.753
regulation of triglyceride metabolic process GO:0090207 11 0.708
regulation of lipase activity GO:0060191 37 0.655
regulation of cellular ketone metabolic process GO:0010565 50 0.644
regulation of protein secretion GO:0050708 86 0.593
regulation of plasma lipoprotein particle levels GO:0097006 32 0.565
regulation of protein transport GO:0051223 213 0.542
lipid metabolic process GO:0006629 381 0.537
neutral lipid metabolic process GO:0006638 27 0.534
negative regulation of transport GO:0051051 176 0.524
carboxylic acid biosynthetic process GO:0046394 97 0.523
negative regulation of proteolysis GO:0045861 132 0.493
positive regulation of transport GO:0051050 336 0.490
acylglycerol metabolic process GO:0006639 27 0.490
myeloid cell differentiation GO:0030099 117 0.481
cardiovascular system development GO:0072358 262 0.447
negative regulation of protein processing GO:0010955 142 0.423
regulation of protein localization GO:0032880 296 0.412
response to hormone GO:0009725 175 0.400
circulatory system development GO:0072359 262 0.398
cellular lipid metabolic process GO:0044255 303 0.389
cholesterol homeostasis GO:0042632 28 0.382
negative regulation of protein maturation GO:1903318 142 0.358
monocarboxylic acid metabolic process GO:0032787 185 0.357
triglyceride biosynthetic process GO:0019432 10 0.355
positive regulation of lipid metabolic process GO:0045834 50 0.355
cellular response to lipid GO:0071396 127 0.355
glycerolipid metabolic process GO:0046486 107 0.341
transmembrane transport GO:0055085 399 0.330
regulation of endopeptidase activity GO:0052548 170 0.329
positive regulation of toll like receptor 4 signaling pathway GO:0034145 6 0.327
regulation of proteolysis GO:0030162 293 0.320
regulation of triglyceride biosynthetic process GO:0010866 5 0.309
cellular ketone metabolic process GO:0042180 80 0.308
positive regulation of lipase activity GO:0060193 28 0.306
triglyceride metabolic process GO:0006641 23 0.301
response to lipid GO:0033993 206 0.299
innate immune response GO:0045087 178 0.294
response to organic cyclic compound GO:0014070 204 0.293
Rat
pancreatic juice secretion GO:0030157 4 0.292
cellular response to hormone stimulus GO:0032870 125 0.291
positive regulation of lipid biosynthetic process GO:0046889 22 0.288
positive regulation of cellular component organization GO:0051130 376 0.287
fatty acid biosynthetic process GO:0006633 46 0.287
regulation of protein maturation GO:1903317 150 0.282
glycerolipid biosynthetic process GO:0045017 51 0.278
negative regulation of protein metabolic process GO:0051248 391 0.277
vasculature development GO:0001944 181 0.276
positive regulation of immune system process GO:0002684 283 0.265
oogenesis GO:0048477 2 0.259
regulation of peptidase activity GO:0052547 180 0.255
immune system development GO:0002520 195 0.254
engulfment of apoptotic cell GO:0043652 2 0.249
protein secretion GO:0009306 98 0.244
protein lipid complex subunit organization GO:0071825 24 0.234
hemopoiesis GO:0030097 180 0.234
secretion GO:0046903 254 0.228
fatty acid metabolic process GO:0006631 115 0.226
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.223
cellular response to biotic stimulus GO:0071216 71 0.219
regulation of lipoprotein lipase activity GO:0051004 12 0.218
response to steroid hormone GO:0048545 80 0.217
acylglycerol biosynthetic process GO:0046463 11 0.216
ion transmembrane transport GO:0034220 338 0.213
positive regulation of hydrolase activity GO:0051345 331 0.211
regulation of interleukin 8 secretion GO:2000482 13 0.207
neutral lipid biosynthetic process GO:0046460 11 0.206
negative regulation of peptidase activity GO:0010466 91 0.204
response to abiotic stimulus GO:0009628 336 0.196
regulation of secretion GO:0051046 194 0.194
autophagy GO:0006914 88 0.189
regulation of sterol transport GO:0032371 21 0.186
regulation of protein processing GO:0070613 150 0.184
endocytosis GO:0006897 159 0.183
blood vessel morphogenesis GO:0048514 162 0.182
cellular amine metabolic process GO:0044106 41 0.181
positive regulation of lipoprotein lipase activity GO:0051006 7 0.180
lipid localization GO:0010876 106 0.179
amine metabolic process GO:0009308 44 0.176
positive regulation of lipid storage GO:0010884 10 0.171
cholesterol transport GO:0030301 39 0.169
regulation of vesicle mediated transport GO:0060627 130 0.167
positive regulation of toll like receptor signaling pathway GO:0034123 10 0.166
regulation of phospholipase a2 activity GO:0032429 4 0.165
positive regulation of triglyceride metabolic process GO:0090208 9 0.163
organic acid biosynthetic process GO:0016053 97 0.163
membrane biogenesis GO:0044091 13 0.160
regulation of system process GO:0044057 101 0.158
response to biotic stimulus GO:0009607 276 0.155
cellular response to glucocorticoid stimulus GO:0071385 4 0.155
positive regulation of cellular component biogenesis GO:0044089 158 0.153
plasma lipoprotein particle organization GO:0071827 22 0.153
osteoclast development GO:0036035 2 0.151
lipid transport GO:0006869 90 0.149
sterol homeostasis GO:0055092 28 0.148
cellular response to endogenous stimulus GO:0071495 336 0.145
lipid biosynthetic process GO:0008610 177 0.145
regulation of homeostatic process GO:0032844 121 0.145
blood vessel development GO:0001568 172 0.144
cellular response to organic cyclic compound GO:0071407 127 0.144
neutrophil clearance GO:0097350 1 0.143
negative regulation of serine type peptidase activity GO:1902572 2 0.142
cellular response to oxygen containing compound GO:1901701 276 0.141
negative regulation of cholesterol storage GO:0010887 4 0.140
protein oligomerization GO:0051259 173 0.136
pinocytosis GO:0006907 8 0.133
interleukin 8 secretion GO:0072606 14 0.133
myeloid leukocyte differentiation GO:0002573 60 0.131
negative regulation of endopeptidase activity GO:0010951 84 0.130
regulation of secretion by cell GO:1903530 177 0.129
negative regulation of phospholipase activity GO:0010519 3 0.127
cell type specific apoptotic process GO:0097285 125 0.126
negative regulation of protein secretion GO:0050709 29 0.125
vesicle mediated transport GO:0016192 371 0.124
positive regulation of triglyceride lipase activity GO:0061365 7 0.119
membrane organization GO:0061024 292 0.118
substantia nigra development GO:0021762 45 0.117
maintenance of location GO:0051235 112 0.114
positive regulation of cellular amine metabolic process GO:0033240 7 0.114
regulation of establishment of protein localization GO:0070201 242 0.113
female gamete generation GO:0007292 2 0.113
system process GO:0003008 349 0.111
cytokine production GO:0001816 247 0.110
osteoclast differentiation GO:0030316 21 0.106
regulation of cholesterol homeostasis GO:2000188 2 0.105
positive regulation of fatty acid metabolic process GO:0045923 11 0.105
negative regulation of secretion GO:0051048 58 0.104
positive regulation of homeostatic process GO:0032846 47 0.103
myeloid cell homeostasis GO:0002262 34 0.099
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.097
membrane raft organization GO:0031579 10 0.097
positive regulation of secretion GO:0051047 116 0.096
regulation of myeloid cell differentiation GO:0045637 81 0.094
positive regulation of secretion by cell GO:1903532 108 0.091
negative regulation of cytokine production GO:0001818 82 0.091
regulation of innate immune response GO:0045088 97 0.090
regulation of cellular component biogenesis GO:0044087 281 0.088
regulation of defense response GO:0031347 154 0.088
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.088
regulation of cholesterol storage GO:0010885 8 0.088
protein tetramerization GO:0051262 47 0.087
positive regulation of vesicle fusion GO:0031340 4 0.086
response to calcium ion GO:0051592 46 0.085
secretion by cell GO:0032940 226 0.084
leukocyte differentiation GO:0002521 98 0.084
hematopoietic or lymphoid organ development GO:0048534 186 0.084
positive regulation of protein transport GO:0051222 135 0.084
cellular response to abiotic stimulus GO:0071214 117 0.084
positive regulation of cell death GO:0010942 263 0.083
Rat
vesicle organization GO:0016050 62 0.083
regulation of cell cycle GO:0051726 393 0.083
response to lipopolysaccharide GO:0032496 70 0.083
response to metal ion GO:0010038 84 0.081
negative regulation of multicellular organismal process GO:0051241 317 0.079
positive regulation of proteolysis GO:0045862 142 0.078
negative regulation of hydrolase activity GO:0051346 182 0.078
response to molecule of bacterial origin GO:0002237 82 0.078
response to radiation GO:0009314 151 0.077
activation of cysteine type endopeptidase activity GO:0097202 57 0.076
determination of adult lifespan GO:0008340 2 0.076
keratinocyte differentiation GO:0030216 36 0.076
organic hydroxy compound transport GO:0015850 63 0.076
regulation of interleukin 8 production GO:0032677 49 0.075
cytokinesis completion of separation GO:0007109 3 0.075
regulation of cytokine production GO:0001817 232 0.074
regulation of cellular amino acid metabolic process GO:0006521 6 0.073
mitotic cell cycle phase transition GO:0044772 162 0.073
negative regulation of programmed cell death GO:0043069 321 0.073
cell cycle arrest GO:0007050 71 0.073
epithelial cell differentiation GO:0030855 141 0.073
positive regulation of peptidase activity GO:0010952 88 0.072
activation of immune response GO:0002253 114 0.071
positive regulation of defense response GO:0031349 87 0.071
receptor metabolic process GO:0043112 81 0.071
neural nucleus development GO:0048857 47 0.071
regulation of serine type peptidase activity GO:1902571 2 0.070
regulation of immune response GO:0050776 201 0.070
lipid homeostasis GO:0055088 39 0.069
response to inorganic substance GO:0010035 127 0.068
response to uv GO:0009411 73 0.068
cellular response to molecule of bacterial origin GO:0071219 62 0.067
negative regulation of cellular component organization GO:0051129 235 0.066
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.066
apoptotic cell clearance GO:0043277 12 0.066
activation of innate immune response GO:0002218 55 0.065
negative regulation of cellular protein metabolic process GO:0032269 353 0.065
apoptotic mitochondrial changes GO:0008637 57 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.063
negative regulation of lipid transport GO:0032369 18 0.062
anatomical structure formation involved in morphogenesis GO:0048646 284 0.061
multicellular organismal aging GO:0010259 3 0.061
positive regulation of innate immune response GO:0045089 79 0.061
positive regulation of fatty acid biosynthetic process GO:0045723 5 0.061
cellular response to radiation GO:0071478 65 0.060
cellular amino acid metabolic process GO:0006520 116 0.060
chemical homeostasis GO:0048878 306 0.059
positive regulation of endopeptidase activity GO:0010950 84 0.059
nervous system development GO:0007399 293 0.059
receptor biosynthetic process GO:0032800 18 0.058
negative regulation of protein transport GO:0051224 75 0.057
positive regulation of programmed cell death GO:0043068 249 0.057
Rat
i kappab kinase nf kappab signaling GO:0007249 166 0.056
single organism membrane fusion GO:0044801 37 0.056
regulation of cellular amine metabolic process GO:0033238 11 0.055
positive regulation of apoptotic process GO:0043065 246 0.055
Rat
protein catabolic process GO:0030163 325 0.054
cell division GO:0051301 168 0.054
signal transduction by p53 class mediator GO:0072331 72 0.053
endosome organization GO:0007032 20 0.053
mitochondrion organization GO:0007005 156 0.053
regulation of receptor biosynthetic process GO:0010869 15 0.053
response to oxygen containing compound GO:1901700 369 0.053
Rat
positive regulation of cell cycle process GO:0090068 106 0.053
regulation of cell differentiation GO:0045595 393 0.053
positive regulation of protein secretion GO:0050714 60 0.052
membrane budding GO:0006900 28 0.051
pattern recognition receptor signaling pathway GO:0002221 48 0.051
dna damage checkpoint GO:0000077 68 0.050
extrinsic apoptotic signaling pathway GO:0097191 119 0.050
negative regulation of intracellular signal transduction GO:1902532 183 0.050
trail activated apoptotic signaling pathway GO:0036462 4 0.049
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.049
regulation of body fluid levels GO:0050878 99 0.049
protein localization to nucleus GO:0034504 136 0.048
negative regulation of apoptotic process GO:0043066 316 0.048
apoptotic signaling pathway GO:0097190 268 0.048
negative regulation of interleukin 8 secretion GO:2000483 2 0.047
positive regulation of immune response GO:0050778 159 0.047
negative regulation of cell cycle process GO:0010948 121 0.047
carbohydrate metabolic process GO:0005975 207 0.046
cholesterol efflux GO:0033344 28 0.044
cell cycle checkpoint GO:0000075 117 0.043
purine nucleotide catabolic process GO:0006195 405 0.043
head development GO:0060322 108 0.043
cytokinesis GO:0000910 96 0.042
positive regulation of organelle organization GO:0010638 195 0.042
execution phase of apoptosis GO:0097194 32 0.042
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.042
regulation of serine type endopeptidase activity GO:1900003 2 0.042
cellular homeostasis GO:0019725 196 0.041
neutrophil homeostasis GO:0001780 3 0.041
response to light stimulus GO:0009416 87 0.040
regulation of digestive system process GO:0044058 5 0.040
positive regulation of cell differentiation GO:0045597 211 0.040
membrane raft assembly GO:0001765 7 0.040
regulation of cell cycle arrest GO:0071156 36 0.040
cellular response to corticosteroid stimulus GO:0071384 5 0.040
small molecule biosynthetic process GO:0044283 157 0.039
negative regulation of serine type endopeptidase activity GO:1900004 2 0.039
membrane fusion GO:0061025 43 0.038
epithelium development GO:0060429 227 0.038
regulation of fatty acid biosynthetic process GO:0042304 9 0.038
negative regulation of cell death GO:0060548 345 0.038
cellular response to dna damage stimulus GO:0006974 379 0.038
cell cycle phase transition GO:0044770 173 0.038
regulation of cellular response to stress GO:0080135 244 0.037
positive regulation of cell proliferation GO:0008284 301 0.037
regulation of cytokine secretion GO:0050707 57 0.037
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.037
response to cytokine GO:0034097 232 0.036
endomembrane system organization GO:0010256 196 0.036
positive regulation of cholesterol transport GO:0032376 10 0.036
carbohydrate derivative biosynthetic process GO:1901137 207 0.036
positive regulation of phosphorylation GO:0042327 394 0.035
positive regulation of intracellular transport GO:0032388 104 0.035
regulation of cell cycle process GO:0010564 266 0.035
sterol transport GO:0015918 39 0.035
peptide cross linking GO:0018149 12 0.035
regulation of phospholipase activity GO:0010517 26 0.034
homeostasis of number of cells GO:0048872 40 0.034
negative regulation of phosphate metabolic process GO:0045936 267 0.034
release of cytochrome c from mitochondria GO:0001836 35 0.034
protein localization to organelle GO:0033365 280 0.033
brain development GO:0007420 97 0.033
organonitrogen compound biosynthetic process GO:1901566 200 0.033
nucleocytoplasmic transport GO:0006913 176 0.033
intracellular receptor signaling pathway GO:0030522 104 0.032
cell development GO:0048468 328 0.032
cellular macromolecule catabolic process GO:0044265 380 0.032
regulation of lipid transport GO:0032368 44 0.032
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.032
angiogenesis GO:0001525 147 0.032
single organism membrane organization GO:0044802 268 0.032
response to external biotic stimulus GO:0043207 261 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.032
positive regulation of protein phosphorylation GO:0001934 313 0.031
positive regulation of cell cycle arrest GO:0071158 23 0.031
interleukin 8 production GO:0032637 51 0.031
innate immune response activating signal transduction GO:0002758 48 0.031
cytoplasmic transport GO:0016482 379 0.031
retinoic acid receptor signaling pathway GO:0048384 13 0.031
response to tumor necrosis factor GO:0034612 76 0.031
response to bacterium GO:0009617 144 0.030
epidermal cell differentiation GO:0009913 45 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
biological adhesion GO:0022610 331 0.030
cellular chemical homeostasis GO:0055082 180 0.030
negative regulation of cell proliferation GO:0008285 228 0.030
regulation of mitotic cell cycle phase transition GO:1901990 118 0.029
response to ketone GO:1901654 19 0.029
negative regulation of cell cycle phase transition GO:1901988 89 0.029
positive regulation of lipid transport GO:0032370 22 0.029
cytokine secretion GO:0050663 64 0.029
regulation of mitotic cell cycle GO:0007346 189 0.029
mitotic cell cycle GO:0000278 326 0.029
response to corticosteroid GO:0031960 15 0.029
mitotic cell cycle checkpoint GO:0007093 68 0.029
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.028
glycerophospholipid metabolic process GO:0006650 84 0.028
central nervous system development GO:0007417 123 0.028
nuclear transport GO:0051169 179 0.028
single organism reproductive process GO:0044702 98 0.028
cellular response to lipopolysaccharide GO:0071222 57 0.028
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.027
regulation of cytoplasmic transport GO:1903649 149 0.027
cellular response to mechanical stimulus GO:0071260 39 0.027
negative regulation of endocytosis GO:0045806 19 0.027
regulation of endocytosis GO:0030100 72 0.027
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.027
cell morphogenesis GO:0000902 296 0.027
single organism nuclear import GO:1902593 104 0.026
establishment of protein localization to organelle GO:0072594 172 0.026
regulation of synaptic plasticity GO:0048167 3 0.026
neuromuscular junction development GO:0007528 3 0.026
positive regulation of neuron death GO:1901216 14 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
epithelial cell proliferation GO:0050673 128 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.026
cholesterol storage GO:0010878 9 0.026
protein targeting to nucleus GO:0044744 104 0.025
sulfur compound metabolic process GO:0006790 101 0.025
intracellular protein transport GO:0006886 270 0.025
positive regulation of developmental process GO:0051094 314 0.025
tissue remodeling GO:0048771 16 0.025
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
regulation of fatty acid metabolic process GO:0019217 24 0.025
plasma lipoprotein particle assembly GO:0034377 9 0.025
regulation of nucleocytoplasmic transport GO:0046822 98 0.025
cellular response to uv GO:0034644 32 0.025
cellular response to cytokine stimulus GO:0071345 181 0.025
small gtpase mediated signal transduction GO:0007264 78 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
skin development GO:0043588 76 0.024
mitotic cell cycle process GO:1903047 286 0.024
nucleotide catabolic process GO:0009166 408 0.024
positive regulation of cell cycle GO:0045787 140 0.024
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.024
membrane assembly GO:0071709 10 0.024
defense response GO:0006952 315 0.024
post embryonic development GO:0009791 2 0.024
immune response regulating signaling pathway GO:0002764 97 0.024
regulation of cysteine type endopeptidase activity GO:2000116 127 0.024
erythrocyte homeostasis GO:0034101 31 0.023
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.023
heart development GO:0007507 95 0.023
protein homooligomerization GO:0051260 100 0.023
regulation of protein import into nucleus GO:0042306 78 0.023
protein import GO:0017038 130 0.023
zymogen activation GO:0031638 70 0.023
anion transport GO:0006820 161 0.023
regulation of cell cycle phase transition GO:1901987 126 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
cation transmembrane transport GO:0098655 238 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
embryo development GO:0009790 123 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
ion homeostasis GO:0050801 230 0.022
cell adhesion GO:0007155 325 0.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.022
neuron death GO:0070997 65 0.022
g1 s transition of mitotic cell cycle GO:0000082 78 0.022
mitotic dna damage checkpoint GO:0044773 28 0.022
divalent inorganic cation homeostasis GO:0072507 136 0.022
signal transduction in response to dna damage GO:0042770 57 0.021
protein import into nucleus GO:0006606 104 0.021
aging GO:0007568 66 0.021
cell projection organization GO:0030030 252 0.021
positive regulation of catabolic process GO:0009896 310 0.021
behavior GO:0007610 112 0.021
negative regulation of cell cycle GO:0045786 193 0.021
protein lipid complex assembly GO:0065005 12 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
cellular protein catabolic process GO:0044257 261 0.021
nucleoside catabolic process GO:0009164 408 0.021
locomotory behavior GO:0007626 1 0.020
cell growth GO:0016049 160 0.020
cellular ion homeostasis GO:0006873 168 0.020
purine containing compound catabolic process GO:0072523 411 0.020
regulation of response to dna damage stimulus GO:2001020 94 0.020
protein targeting GO:0006605 187 0.020
regeneration GO:0031099 4 0.020
phospholipid metabolic process GO:0006644 99 0.020
positive regulation of receptor biosynthetic process GO:0010870 8 0.020
regulation of myeloid leukocyte differentiation GO:0002761 39 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.020
negative regulation of cytokine secretion GO:0050710 20 0.020
regulation of cell cycle g1 s phase transition GO:1902806 42 0.019
secretion by tissue GO:0032941 9 0.019
regulation of lipid storage GO:0010883 21 0.019
ribonucleoside catabolic process GO:0042454 406 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.019
metal ion homeostasis GO:0055065 169 0.019
regulation of intracellular transport GO:0032386 195 0.018
vesicle fusion GO:0006906 17 0.018
regulation of angiogenesis GO:0045765 92 0.018
single organism cellular localization GO:1902580 332 0.018
organelle fusion GO:0048284 36 0.018
neuron apoptotic process GO:0051402 39 0.018
response to mechanical stimulus GO:0009612 51 0.018
positive regulation of cytoplasmic transport GO:1903651 82 0.018
spermatid differentiation GO:0048515 4 0.018
social behavior GO:0035176 14 0.018
cellular cation homeostasis GO:0030003 163 0.018
cation homeostasis GO:0055080 189 0.018
regulation of epithelial cell proliferation GO:0050678 113 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
multicellular organismal reproductive process GO:0048609 40 0.018
response to progesterone GO:0032570 5 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
phagocytosis GO:0006909 42 0.017
organophosphate catabolic process GO:0046434 430 0.017
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9 0.017
multicellular organismal response to stress GO:0033555 1 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
neural tube formation GO:0001841 3 0.016
regulation of leukocyte differentiation GO:1902105 61 0.016
regulation of protein targeting GO:1903533 91 0.016
cellular response to external stimulus GO:0071496 111 0.016
regulation of neuron death GO:1901214 56 0.016
regulation of locomotion GO:0040012 329 0.016
neurological system process GO:0050877 163 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
response to hyperoxia GO:0055093 4 0.016
erythrocyte differentiation GO:0030218 28 0.016
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.016
cell activation GO:0001775 213 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.016
cellular calcium ion homeostasis GO:0006874 117 0.016
rho protein signal transduction GO:0007266 26 0.016
lipid storage GO:0019915 28 0.016
myeloid cell development GO:0061515 5 0.016
regulation of kinase activity GO:0043549 314 0.016
regulation of toll like receptor signaling pathway GO:0034121 17 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.015
glycoprotein metabolic process GO:0009100 110 0.015
regulation of cell growth GO:0001558 135 0.015
response to alcohol GO:0097305 64 0.015
regulation of protein kinase activity GO:0045859 289 0.015
cell fate determination GO:0001709 3 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
cellular response to light stimulus GO:0071482 34 0.015
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.015
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.015
rhythmic behavior GO:0007622 2 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.015
regulation of cell adhesion GO:0030155 166 0.015
regulation of response to external stimulus GO:0032101 222 0.015
high density lipoprotein particle assembly GO:0034380 5 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
negative regulation of lipid storage GO:0010888 11 0.015
response to growth factor GO:0070848 205 0.015
positive regulation of leukocyte differentiation GO:1902107 37 0.015
glycoprotein biosynthetic process GO:0009101 91 0.015
negative regulation of protein kinase activity GO:0006469 98 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
ossification GO:0001503 121 0.014
toll like receptor 4 signaling pathway GO:0034142 12 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
segmentation GO:0035282 4 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
response to hypoxia GO:0001666 96 0.014
response to salt stress GO:0009651 3 0.014
regulation of cell motility GO:2000145 299 0.014

SMPD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.077
inherited metabolic disorder DOID:655 242 0.077
immune system disease DOID:2914 155 0.039
musculoskeletal system disease DOID:17 223 0.030
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.017
connective tissue disease DOID:65 109 0.017
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
central nervous system disease DOID:331 186 0.015