|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
1.000
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
1.000
|
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.998
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.996
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.989
|
Yeast |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.988
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.987
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.983
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.982
|
Yeast |
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.976
|
Human |
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.975
|
Human |
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.974
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.974
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.973
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.965
|
Yeast |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.963
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.962
|
|
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.957
|
Human |
|
|
regulation of rrna processing
|
GO:2000232 |
1 |
0.939
|
Yeast |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.931
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.927
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.916
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.916
|
Human Yeast |
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.912
|
|
|
|
negative regulation of potassium ion transmembrane transport
|
GO:1901380 |
5 |
0.911
|
Human |
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.911
|
Yeast |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.908
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.904
|
|
|
|
transmission of virus
|
GO:0019089 |
1 |
0.901
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.897
|
|
|
|
dissemination or transmission of symbiont from host
|
GO:0044007 |
1 |
0.896
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.891
|
Human |
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.868
|
Human |
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.861
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.849
|
Yeast |
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.845
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.844
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.843
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.835
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.830
|
Human |
|
|
chromatin silencing at rdna
|
GO:0000183 |
5 |
0.828
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.826
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.826
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.820
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.818
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.807
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.803
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.788
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.764
|
|
|
|
polyprenol metabolic process
|
GO:0016093 |
3 |
0.763
|
Yeast |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.761
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.751
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.750
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.749
|
|
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.734
|
Yeast |
|
|
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010768 |
1 |
0.725
|
Human |
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.725
|
Yeast |
|
|
dolichol metabolic process
|
GO:0019348 |
3 |
0.724
|
Yeast |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.723
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.717
|
|
|
|
regulation of multivesicular body size
|
GO:0010796 |
1 |
0.709
|
Yeast |
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.696
|
Yeast |
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.684
|
Human Yeast |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.683
|
Human |
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.670
|
Yeast |
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.648
|
Yeast |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.645
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.645
|
Yeast |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.640
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.631
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.621
|
Yeast |
|
|
trna export from nucleus
|
GO:0006409 |
1 |
0.618
|
Yeast |
|
|
meiosis i
|
GO:0007127 |
4 |
0.617
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.608
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.602
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.597
|
|
|
|
growth
|
GO:0040007 |
202 |
0.594
|
Fly |
|
|
transcription from rna polymerase i promoter
|
GO:0006360 |
11 |
0.585
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.572
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.561
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.558
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.549
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.548
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.535
|
|
|
|
dissemination or transmission of organism from other organism involved in symbiotic interaction
|
GO:0051821 |
1 |
0.522
|
Human |
|
|
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010767 |
1 |
0.518
|
Human |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.514
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.514
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.511
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.508
|
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.505
|
|
|
|
quinone biosynthetic process
|
GO:1901663 |
6 |
0.492
|
Yeast |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.489
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.486
|
Yeast |
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
10 |
0.485
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.483
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.481
|
Yeast Fly |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.481
|
|
|
|
negative regulation of chromatin silencing at rdna
|
GO:0061188 |
2 |
0.479
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.471
|
Human |
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.468
|
|
|
|
negative regulation of potassium ion transmembrane transporter activity
|
GO:1901017 |
3 |
0.462
|
Human |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.459
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.458
|
|
|
|
system process
|
GO:0003008 |
349 |
0.458
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.453
|
Fly |
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
1 |
0.452
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.448
|
Human Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.447
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.441
|
Yeast |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.440
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.440
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.432
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.429
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.427
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.425
|
|
|
|
quinone metabolic process
|
GO:1901661 |
18 |
0.423
|
Yeast |
|
|
histone h4 k8 acetylation
|
GO:0043982 |
15 |
0.417
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.417
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.396
|
Human Yeast |
|
|
regulation of mesoderm development
|
GO:2000380 |
4 |
0.394
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.390
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.388
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.386
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.376
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.376
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.374
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.371
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.364
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.361
|
Human Yeast |
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.358
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.354
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.354
|
|
|
|
establishment of rna localization
|
GO:0051236 |
39 |
0.353
|
Yeast |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.351
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.346
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.342
|
Human |
|
|
heart valve formation
|
GO:0003188 |
2 |
0.337
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.335
|
Yeast |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.334
|
|
|
|
trna processing
|
GO:0008033 |
23 |
0.332
|
Yeast |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.329
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.329
|
|
|
|
sperm motility
|
GO:0030317 |
6 |
0.327
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.325
|
|
|
|
protein targeting to vacuole
|
GO:0006623 |
8 |
0.319
|
Human |
|
|
nuclear division
|
GO:0000280 |
128 |
0.316
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.316
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.316
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.316
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.315
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.310
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
4 |
0.310
|
Yeast |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.307
|
Yeast |
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.306
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.306
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.304
|
Yeast |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.302
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.302
|
Yeast |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.299
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.299
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.296
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.295
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.295
|
|
|
|
histone h4 k5 acetylation
|
GO:0043981 |
15 |
0.294
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.293
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.291
|
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
13 |
0.291
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.288
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.287
|
Human Yeast |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.285
|
Yeast |
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.281
|
Yeast |
|
|
lipid localization
|
GO:0010876 |
106 |
0.278
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.276
|
Yeast |
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.275
|
Human |
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.273
|
Yeast |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.272
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.271
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.270
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.269
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.269
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.266
|
|
|
|
isoprenoid biosynthetic process
|
GO:0008299 |
9 |
0.263
|
Yeast |
|
|
immune response
|
GO:0006955 |
307 |
0.258
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.257
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.256
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.255
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.254
|
Yeast |
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
5 |
0.251
|
Yeast |
|
|
male meiosis
|
GO:0007140 |
1 |
0.250
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.248
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.247
|
|
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.245
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.240
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.240
|
Yeast |
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.239
|
Yeast |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.234
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.232
|
Human Yeast |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.232
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.231
|
Yeast |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.231
|
|
|
|
mrna transport
|
GO:0051028 |
30 |
0.230
|
Yeast |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.228
|
Yeast |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.228
|
Yeast |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.226
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.226
|
|
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
1 |
0.224
|
|
|
|
bleb assembly
|
GO:0032060 |
6 |
0.223
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.222
|
|
|
|
ribosome localization
|
GO:0033750 |
4 |
0.219
|
Yeast |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.218
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.215
|
Yeast |
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.213
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.212
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.210
|
Yeast |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.208
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.207
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.205
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.203
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.203
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.200
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.200
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.200
|
Yeast |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.197
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.197
|
|
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.195
|
Yeast |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.194
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.193
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.193
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.192
|
Yeast |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.188
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.188
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.187
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.186
|
|
|
|
regulation of ectodermal cell fate specification
|
GO:0042665 |
1 |
0.185
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.185
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.182
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
0.182
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.181
|
Yeast |
|
|
somitogenesis
|
GO:0001756 |
2 |
0.181
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.180
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.178
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.178
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.178
|
|
|
|
regulation of chromatin silencing at rdna
|
GO:0061187 |
2 |
0.177
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.177
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.177
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.175
|
|
|
|
negative regulation of transcription from rna polymerase i promoter
|
GO:0016479 |
2 |
0.172
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.171
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.171
|
|
|
|
regulation of ectoderm development
|
GO:2000383 |
1 |
0.171
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.171
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.170
|
Yeast |
|
|
cell division
|
GO:0051301 |
168 |
0.169
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
2 |
0.169
|
|
|
|
regulation of nodal signaling pathway involved in determination of left right asymmetry
|
GO:1900145 |
1 |
0.169
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.168
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.168
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.167
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.167
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.166
|
Yeast |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.165
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.165
|
Yeast |
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.164
|
Human |
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.163
|
|
|
|
ribonucleoprotein complex export from nucleus
|
GO:0071426 |
4 |
0.162
|
Yeast |
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.161
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.159
|
Human |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.158
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.158
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.157
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.157
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.157
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.155
|
Human Yeast |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.155
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.155
|
Yeast |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.155
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.153
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.152
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.151
|
|
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.150
|
Human |
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.149
|
Human |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.148
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.144
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.143
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.143
|
Yeast |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.142
|
Human |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.141
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.140
|
Yeast |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.139
|
Yeast |
|
|
protein localization to lysosome
|
GO:0061462 |
11 |
0.139
|
Human |
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
5 |
0.139
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.138
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.137
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.136
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.135
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.134
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.134
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.133
|
|
|
|
cellular response to histamine
|
GO:0071420 |
3 |
0.133
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.133
|
Human |
|
|
histone h4 k12 acetylation
|
GO:0043983 |
6 |
0.132
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.132
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.131
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.130
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.129
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.129
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.129
|
Human |
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.128
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.124
|
Yeast |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.123
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.123
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.123
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.122
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.122
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.122
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.121
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.120
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.120
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.120
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.119
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.118
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.117
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.117
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.117
|
Human |
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.116
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.115
|
|
|
|
ectodermal cell fate specification
|
GO:0001715 |
1 |
0.115
|
|
|
|
t cell cytokine production
|
GO:0002369 |
12 |
0.115
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.115
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.114
|
Human Yeast |
|
|
response to host
|
GO:0075136 |
2 |
0.113
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.113
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.112
|
Human |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.112
|
Human |
|
|
protein acetylation
|
GO:0006473 |
116 |
0.111
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.110
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.110
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.110
|
Yeast |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.109
|
Yeast |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.109
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.109
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.108
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.107
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.107
|
Yeast |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.107
|
Human |
|
|
positive regulation of amine transport
|
GO:0051954 |
2 |
0.106
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.105
|
|
|
|
negative regulation of potassium ion transport
|
GO:0043267 |
6 |
0.104
|
Human |
|
|
ectoderm development
|
GO:0007398 |
3 |
0.104
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.103
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.103
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.103
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.103
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.102
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.102
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.101
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.101
|
Yeast |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.101
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.101
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.100
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
3 |
0.100
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.100
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.100
|
Human |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.099
|
Human |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.099
|
Fly |
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.098
|
Yeast |
|
|
response to fluid shear stress
|
GO:0034405 |
14 |
0.098
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.097
|
Yeast Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.097
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.096
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.096
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.096
|
Yeast |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.094
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.093
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.093
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.093
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.092
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.091
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.091
|
Fly |
|
|
regulation of protein homodimerization activity
|
GO:0043496 |
9 |
0.091
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.091
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.090
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.089
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.089
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.087
|
Human |
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
0.087
|
|
|
|
trna metabolic process
|
GO:0006399 |
35 |
0.087
|
Yeast |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.086
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.086
|
Yeast Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.086
|
Yeast |
|
|
cytokine production
|
GO:0001816 |
247 |
0.085
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.084
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.084
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.084
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.084
|
|
|
|
male gonad development
|
GO:0008584 |
23 |
0.082
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.082
|
|
|
|
hemoglobin biosynthetic process
|
GO:0042541 |
3 |
0.082
|
|
|
|
negative regulation of mesodermal cell fate specification
|
GO:0042662 |
1 |
0.082
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.081
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.081
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.081
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.080
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.080
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.080
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.080
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.079
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.079
|
|
|
|
positive regulation of gene expression epigenetic
|
GO:0045815 |
7 |
0.077
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.077
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.077
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.077
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.077
|
Human Yeast |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.076
|
Yeast |
|
|
response to host defenses
|
GO:0052200 |
2 |
0.076
|
|
|
|
mrna export from nucleus
|
GO:0006406 |
29 |
0.076
|
Yeast |
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.076
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.076
|
Human |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.075
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.075
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.075
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.075
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.074
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.074
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.074
|
Human Yeast |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.074
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.074
|
Human |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.074
|
|
|
|
ossification involved in bone maturation
|
GO:0043931 |
4 |
0.073
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.073
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.073
|
Human |
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.072
|
Fly |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.072
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.072
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.071
|
Yeast Fly |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.071
|
|
|
|
regulation of hemoglobin biosynthetic process
|
GO:0046984 |
1 |
0.071
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.070
|
|
|
|
determination of left right asymmetry in lateral mesoderm
|
GO:0003140 |
1 |
0.070
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.069
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.069
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.068
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.068
|
Yeast |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.067
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.067
|
|
|
|
regulation of transcription regulatory region dna binding
|
GO:2000677 |
15 |
0.066
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.066
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.066
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.065
|
Yeast |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.064
|
|
|
|
sebaceous gland development
|
GO:0048733 |
1 |
0.064
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.064
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.063
|
Human |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.063
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.063
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.063
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.062
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.062
|
Human |
|
|
progesterone receptor signaling pathway
|
GO:0050847 |
3 |
0.062
|
Human |
|
|
regulation of nodal signaling pathway
|
GO:1900107 |
1 |
0.062
|
|
|
|
evasion or tolerance of host defenses by virus
|
GO:0019049 |
2 |
0.062
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.062
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.061
|
Yeast |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.061
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.061
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.061
|
|
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.061
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.061
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.060
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.060
|
Yeast |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.060
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.060
|
Yeast |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.060
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.059
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.059
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.058
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.058
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.057
|
Human |
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
4 |
0.057
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.057
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.057
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.056
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.056
|
|
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.056
|
Yeast |
|
|
rna export from nucleus
|
GO:0006405 |
33 |
0.056
|
Yeast |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.056
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.056
|
Human |
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.056
|
Yeast |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.056
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.056
|
|
