|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.996
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.992
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.991
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.989
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.988
|
Human Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.987
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.981
|
Human Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.979
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.944
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.908
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.892
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.880
|
Human Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.868
|
Human Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.856
|
Human Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.854
|
Zebrafish Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.853
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.852
|
Human Mouse |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.845
|
Zebrafish Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.842
|
Human Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.821
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.782
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.779
|
Human Mouse Rat |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.770
|
Human |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.762
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.760
|
Human Mouse |
|
|
defense response
|
GO:0006952 |
315 |
0.759
|
Zebrafish |
|
|
segmentation
|
GO:0035282 |
4 |
0.751
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.743
|
Human Mouse |
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.723
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.722
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.715
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.709
|
Human Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.706
|
Human |
|
|
memory
|
GO:0007613 |
3 |
0.705
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.692
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.681
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.675
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.675
|
Human Mouse Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.661
|
Human Mouse Rat |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.657
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.648
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.647
|
Human Mouse |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.645
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.645
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.639
|
Human Mouse |
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.636
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.629
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.628
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.626
|
Human Rat |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.592
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.585
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.580
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.574
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.564
|
Human Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.562
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.559
|
Human Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.554
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.536
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.534
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.532
|
Human |
|
|
long term memory
|
GO:0007616 |
2 |
0.531
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.520
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.516
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.513
|
Human Rat |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.511
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.510
|
Zebrafish |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.507
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.501
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.496
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.496
|
Human |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.491
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.487
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.487
|
Mouse |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.486
|
Zebrafish Mouse Rat |
|
|
immune effector process
|
GO:0002252 |
159 |
0.481
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.470
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.469
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.464
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.462
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.452
|
Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.452
|
Human Mouse Rat |
|
|
peptide secretion
|
GO:0002790 |
51 |
0.449
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.448
|
Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.442
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.441
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.437
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.434
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.430
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.428
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.423
|
Zebrafish Mouse |
|
|
response to estradiol
|
GO:0032355 |
23 |
0.421
|
Human Rat |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.413
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.411
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.407
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.403
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.403
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.395
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.395
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.393
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.392
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.391
|
Human Mouse Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.386
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.385
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.382
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.372
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.361
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.360
|
Human Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.359
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.355
|
Human Mouse Rat |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.352
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.349
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.348
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.341
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.338
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.335
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.331
|
Human |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.330
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.327
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.326
|
Zebrafish Mouse |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.326
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.319
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.314
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.306
|
Human Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.303
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.301
|
Human Rat |
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.299
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.298
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.298
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.297
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.297
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.295
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.293
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.288
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.287
|
Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.280
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.278
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.276
|
Zebrafish |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.275
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.273
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.273
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.271
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.268
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.266
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.265
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.262
|
Human Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.261
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.255
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.254
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.252
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.251
|
|
|
|
negative regulation of striated muscle cell apoptotic process
|
GO:0010664 |
2 |
0.251
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.251
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.250
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.250
|
Mouse |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.250
|
|
|
|
system process
|
GO:0003008 |
349 |
0.248
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.248
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.248
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.247
|
Human Rat |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.246
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.241
|
Human Mouse |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.239
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.238
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.236
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.235
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.235
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.234
|
Rat |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.234
|
Zebrafish |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.230
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.228
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.226
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.222
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.221
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.221
|
Zebrafish |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.221
|
Mouse |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.220
|
Human |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.217
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.217
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.216
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.215
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.215
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.212
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.212
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.210
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.209
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.209
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.208
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.207
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.205
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
0.204
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.203
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.203
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.202
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.202
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.201
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.201
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.200
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.200
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.198
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.198
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.198
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
65 |
0.198
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.197
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.195
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.193
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.193
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.191
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.190
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.188
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.186
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.183
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.182
|
Human Mouse |
|
|
immune system development
|
GO:0002520 |
195 |
0.181
|
Zebrafish |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.179
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.177
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.176
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.174
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.173
|
Human Mouse |
|
|
peptide transport
|
GO:0015833 |
74 |
0.172
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.170
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.168
|
Human Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.166
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.165
|
Rat |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.164
|
Human |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.163
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.162
|
Human Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.161
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.159
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.158
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.156
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.156
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.155
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.154
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.154
|
Human Mouse |
|
|
innate immune response
|
GO:0045087 |
178 |
0.153
|
Zebrafish |
|
|
regionalization
|
GO:0003002 |
29 |
0.151
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.149
|
Rat |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.148
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.145
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.144
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.143
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.142
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.142
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.142
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.142
|
Human |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.141
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.140
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.139
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.139
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.139
|
Zebrafish |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.138
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.137
|
Human |
|
|
compound eye development
|
GO:0048749 |
1 |
0.136
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.136
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.135
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.134
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.132
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.132
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.132
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.132
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.131
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.131
|
Zebrafish Mouse |
|
|
gland development
|
GO:0048732 |
48 |
0.130
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.130
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.129
|
|
|
|
cellular response to interleukin 12
|
GO:0071349 |
3 |
0.129
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.129
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.129
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.127
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.125
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.124
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.124
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.123
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.122
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.121
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.120
|
Zebrafish |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.119
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.116
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.116
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.115
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.115
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.115
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.114
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.114
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.113
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.113
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.113
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.112
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.111
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.111
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.110
|
Zebrafish |
|
|
gastrulation
|
GO:0007369 |
51 |
0.109
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.108
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.108
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.106
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.106
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.104
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.104
|
Zebrafish Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.104
|
Human Mouse |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.104
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.104
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.103
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.103
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.103
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.102
|
|
|
|
hypoxia inducible factor 1alpha signaling pathway
|
GO:0097411 |
3 |
0.101
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.101
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.100
|
Mouse |
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.100
|
Mouse |
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.100
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.099
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.099
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.099
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.098
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.095
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.094
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.094
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.094
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.093
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.093
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.092
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.091
|
|
|
|
interleukin 1 production
|
GO:0032612 |
26 |
0.090
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
6 |
0.090
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.089
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.089
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.088
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.088
|
Human Rat |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.088
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.087
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.086
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.086
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.086
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.086
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.085
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.085
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.085
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.083
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.083
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.083
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.082
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.082
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.082
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.081
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.081
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.081
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.079
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.079
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.079
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.079
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.079
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.079
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.077
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.077
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.077
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.076
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.076
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.076
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.076
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.076
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.074
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.074
|
|
|
|
growth
|
GO:0040007 |
202 |
0.074
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.074
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.073
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.073
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.073
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.073
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.071
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.071
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.071
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.071
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.070
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.070
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.070
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.069
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.069
|
Human |
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.068
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.068
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.068
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.067
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.067
|
Zebrafish |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.066
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.066
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.066
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.066
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.065
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.065
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.065
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.065
|
Zebrafish |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.065
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.065
|
Rat |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.065
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.064
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.064
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.062
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.062
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.062
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.060
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.059
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.059
|
|
|
|
negative regulation of cardiac muscle cell apoptotic process
|
GO:0010667 |
2 |
0.059
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.058
|
|
|
|
positive regulation of dna binding
|
GO:0043388 |
17 |
0.058
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.058
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.057
|
|
|
|
interleukin 12 mediated signaling pathway
|
GO:0035722 |
3 |
0.057
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.057
|
Human |
|
|
translation
|
GO:0006412 |
132 |
0.057
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.057
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.057
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
22 |
0.056
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.056
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.056
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.056
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.056
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.056
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.055
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.055
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.054
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
10 |
0.054
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.053
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.053
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
13 |
0.053
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.053
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.053
|
Mouse |
|
|
protein processing
|
GO:0016485 |
226 |
0.053
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.053
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.052
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.052
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.052
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.052
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.052
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.052
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.051
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.051
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.051
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.050
|
Rat |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.050
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.050
|
Zebrafish |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.049
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.049
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.049
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.049
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.049
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.049
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.049
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.049
|
Rat |
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.048
|
|
|
|
response to interleukin 15
|
GO:0070672 |
6 |
0.048
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.048
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.048
|
Zebrafish |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.048
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.048
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.048
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.048
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.047
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.047
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.047
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.047
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
1 |
0.047
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.047
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.046
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.046
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.046
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.046
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.046
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.046
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.045
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
22 |
0.045
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.045
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.045
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.045
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.044
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.044
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.044
|
|
|
|
copper ion homeostasis
|
GO:0055070 |
3 |
0.044
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.044
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.044
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.043
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.042
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.042
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.042
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.042
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.042
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.042
|
Zebrafish |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.041
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.041
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.041
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.040
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.040
|
|
