Homo sapiens

202 known processes

SORL1

sortilin-related receptor, L(DLR class) A repeats containing

(Aliases: SorLA-1,FLJ39258,LRP9,LR11,FLJ21930,C11orf32,SORLA,gp250)

SORL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
plasma membrane to endosome transport GO:0048227 6 0.599
Human
negative regulation of cellular amide metabolic process GO:0034249 3 0.575
endosome to lysosome transport GO:0008333 21 0.531
Human
positive regulation of protein localization to early endosome GO:1902966 2 0.520
regulation of lipoprotein lipase activity GO:0051004 12 0.511
Human
post golgi vesicle mediated transport GO:0006892 36 0.414
regulation of peptidase activity GO:0052547 180 0.341
regulation of locomotion GO:0040012 329 0.338
regulation of cell motility GO:2000145 299 0.300
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.263
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.237
Human
intracellular protein transport GO:0006886 270 0.209
regulation of protein localization to early endosome GO:1902965 2 0.197
golgi vesicle transport GO:0048193 80 0.187
negative regulation of cellular component organization GO:0051129 235 0.183
neurotrophin trk receptor signaling pathway GO:0048011 4 0.170
Human
protein maturation GO:0051604 233 0.164
nerve growth factor signaling pathway GO:0038180 4 0.163
Human
negative regulation of amyloid precursor protein catabolic process GO:1902992 4 0.162
protein targeting to golgi GO:0000042 3 0.162
ras protein signal transduction GO:0007265 73 0.162
g protein coupled receptor signaling pathway GO:0007186 207 0.158
Human
negative regulation of catalytic activity GO:0043086 335 0.153
protein localization to early endosome GO:1902946 2 0.153
response to oxygen containing compound GO:1901700 369 0.151
Human
beta amyloid formation GO:0034205 7 0.142
vacuolar transport GO:0007034 34 0.140
regulation of protein transport GO:0051223 213 0.139
ribonucleoside catabolic process GO:0042454 406 0.131
protein localization to organelle GO:0033365 280 0.130
positive regulation of transport GO:0051050 336 0.128
secretion GO:0046903 254 0.124
negative regulation of protein processing GO:0010955 142 0.124
positive regulation of catabolic process GO:0009896 310 0.123
negative regulation of beta amyloid formation GO:1902430 3 0.122
negative regulation of proteolysis GO:0045861 132 0.118
negative regulation of cellular protein metabolic process GO:0032269 353 0.118
negative regulation of binding GO:0051100 57 0.116
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.115
response to organonitrogen compound GO:0010243 156 0.115
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.111
negative regulation of lipoprotein lipase activity GO:0051005 5 0.108
Human
positive regulation of protein catabolic process GO:0045732 75 0.108
response to growth factor GO:0070848 205 0.107
Human
guanosine containing compound catabolic process GO:1901069 239 0.104
regulation of cell migration GO:0030334 289 0.103
negative regulation of protein oligomerization GO:0032460 8 0.102
response to nitrogen compound GO:1901698 184 0.098
Human
purine ribonucleoside catabolic process GO:0046130 398 0.097
regulation of protein maturation GO:1903317 150 0.094
protein localization to lysosome GO:0061462 11 0.087
regulation of proteolysis GO:0030162 293 0.086
protein processing GO:0016485 226 0.086
purine nucleotide catabolic process GO:0006195 405 0.085
vesicle mediated transport GO:0016192 371 0.085
positive regulation of cytoplasmic transport GO:1903651 82 0.084
negative regulation of hydrolase activity GO:0051346 182 0.078
apoptotic signaling pathway GO:0097190 268 0.077
Human
negative regulation of peptidase activity GO:0010466 91 0.077
endocytic recycling GO:0032456 12 0.075
negative regulation of protein metabolic process GO:0051248 391 0.075
regulation of cellular component biogenesis GO:0044087 281 0.073
purine ribonucleotide catabolic process GO:0009154 404 0.073
purine nucleoside catabolic process GO:0006152 398 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.072
cellular amino acid metabolic process GO:0006520 116 0.068
endosomal transport GO:0016197 129 0.068
female gamete generation GO:0007292 2 0.067
establishment of protein localization to organelle GO:0072594 172 0.066
cellular response to growth factor stimulus GO:0071363 197 0.066
Human
negative regulation of endopeptidase activity GO:0010951 84 0.064
regulation of establishment of protein localization GO:0070201 242 0.063
response to peptide GO:1901652 65 0.063
Human
regulation of protein processing GO:0070613 150 0.062
cellular response to endogenous stimulus GO:0071495 336 0.062
Human
positive regulation of intracellular transport GO:0032388 104 0.061
actin filament based process GO:0030029 224 0.061
amine metabolic process GO:0009308 44 0.059
regulation of cellular amine metabolic process GO:0033238 11 0.059
post embryonic development GO:0009791 2 0.059
macromolecule glycosylation GO:0043413 63 0.059
maintenance of protein location in cell GO:0032507 56 0.058
system process GO:0003008 349 0.057
glucose transport GO:0015758 30 0.057
Human
nervous system development GO:0007399 293 0.057
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.054
glycoprotein metabolic process GO:0009100 110 0.054
negative regulation of protein maturation GO:1903318 142 0.054
regulation of protein catabolic process GO:0042176 155 0.053
cell projection organization GO:0030030 252 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.050
amyloid precursor protein catabolic process GO:0042987 12 0.049
monosaccharide transport GO:0015749 32 0.048
Human
small gtpase mediated signal transduction GO:0007264 78 0.048
muscle structure development GO:0061061 98 0.048
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.048
single organism carbohydrate metabolic process GO:0044723 193 0.047
cellular ketone metabolic process GO:0042180 80 0.046
positive regulation of cellular amine metabolic process GO:0033240 7 0.044
peptide metabolic process GO:0006518 51 0.043
positive regulation of cellular component organization GO:0051130 376 0.043
cell development GO:0048468 328 0.043
Mouse
nucleoside catabolic process GO:0009164 408 0.043
regulation of vesicle mediated transport GO:0060627 130 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.042
Mouse
protein glycosylation GO:0006486 62 0.042
response to nerve growth factor GO:1990089 6 0.042
Human
regulation of synaptic plasticity GO:0048167 3 0.042
positive regulation of hydrolase activity GO:0051345 331 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.041
single organism cellular localization GO:1902580 332 0.040
secretion by cell GO:0032940 226 0.040
chemical homeostasis GO:0048878 306 0.040
maintenance of location in cell GO:0051651 62 0.040
cellular amine metabolic process GO:0044106 41 0.040
nucleoside phosphate catabolic process GO:1901292 412 0.039
extrinsic apoptotic signaling pathway GO:0097191 119 0.039
Human
response to hormone GO:0009725 175 0.039
Human
toxin transport GO:1901998 4 0.039
generation of neurons GO:0048699 152 0.038
Mouse
locomotory behavior GO:0007626 1 0.038
rho protein signal transduction GO:0007266 26 0.038
ribonucleoside triphosphate catabolic process GO:0009203 391 0.038
regulation of cellular component movement GO:0051270 334 0.038
glycosyl compound catabolic process GO:1901658 413 0.038
maintenance of protein location GO:0045185 57 0.038
defense response GO:0006952 315 0.037
regulation of purine nucleotide metabolic process GO:1900542 264 0.037
nucleotide catabolic process GO:0009166 408 0.037
chemotaxis GO:0006935 157 0.036
gtp catabolic process GO:0006184 237 0.036
biological adhesion GO:0022610 331 0.036
lipid metabolic process GO:0006629 381 0.036
regulation of ras protein signal transduction GO:0046578 155 0.035
negative regulation of protein complex assembly GO:0031333 43 0.035
establishment of protein localization to golgi GO:0072600 4 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.034
memory GO:0007613 3 0.034
protein modification by small protein conjugation GO:0032446 342 0.034
cellular macromolecular complex assembly GO:0034622 324 0.034
single organism membrane organization GO:0044802 268 0.034
multicellular organismal aging GO:0010259 3 0.034
taxis GO:0042330 157 0.034
regulation of gtp catabolic process GO:0033124 180 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
response to abiotic stimulus GO:0009628 336 0.033
cell morphogenesis GO:0000902 296 0.033
vesicle organization GO:0016050 62 0.033
Human
amyloid precursor protein metabolic process GO:0042982 17 0.033
organophosphate catabolic process GO:0046434 430 0.032
carbohydrate derivative biosynthetic process GO:1901137 207 0.032
regulation of reactive oxygen species metabolic process GO:2000377 41 0.032
regulation of cell differentiation GO:0045595 393 0.031
Mouse
gtp metabolic process GO:0046039 239 0.031
oogenesis GO:0048477 2 0.031
muscle cell migration GO:0014812 19 0.031
positive regulation of protein transport GO:0051222 135 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
positive regulation of phosphorylation GO:0042327 394 0.030
guanosine containing compound metabolic process GO:1901068 244 0.030
positive regulation of organelle organization GO:0010638 195 0.030
regulation of cytoplasmic transport GO:1903649 149 0.030
neuromuscular junction development GO:0007528 3 0.029
maintenance of location GO:0051235 112 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
Human
regulation of nucleotide catabolic process GO:0030811 205 0.028
cellular chemical homeostasis GO:0055082 180 0.028
positive regulation of nucleotide metabolic process GO:0045981 230 0.028
actin cytoskeleton organization GO:0030036 207 0.028
purine containing compound catabolic process GO:0072523 411 0.028
determination of adult lifespan GO:0008340 2 0.028
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.026
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.026
cell adhesion GO:0007155 325 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
Mouse
anion transport GO:0006820 161 0.026
glucose import GO:0046323 24 0.026
Human
ion homeostasis GO:0050801 230 0.026
muscle cell differentiation GO:0042692 63 0.026
Human
single organism cell adhesion GO:0098602 179 0.026
ribonucleotide catabolic process GO:0009261 405 0.025
positive regulation of cell death GO:0010942 263 0.025
reactive oxygen species metabolic process GO:0072593 75 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
cellular component morphogenesis GO:0032989 314 0.025
regulation of intracellular transport GO:0032386 195 0.025
response to other organism GO:0051707 261 0.025
rhythmic behavior GO:0007622 2 0.024
carbohydrate transport GO:0008643 37 0.024
Human
endocytosis GO:0006897 159 0.024
Human
organic anion transport GO:0015711 103 0.024
cation homeostasis GO:0055080 189 0.024
nitrogen compound transport GO:0071705 191 0.024
adult locomotory behavior GO:0008344 1 0.023
positive regulation of gtpase activity GO:0043547 166 0.023
regulation of kinase activity GO:0043549 314 0.023
Mouse
intra golgi vesicle mediated transport GO:0006891 8 0.022
response to external biotic stimulus GO:0043207 261 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
glycosylation GO:0070085 71 0.022
neuron differentiation GO:0030182 138 0.022
cation transport GO:0006812 331 0.022
negative regulation of cell death GO:0060548 345 0.022
Mouse
regulation of transferase activity GO:0051338 355 0.022
Mouse
neuron development GO:0048666 113 0.022
positive regulation of cellular component movement GO:0051272 181 0.022
regulation of cytokine production GO:0001817 232 0.022
oocyte differentiation GO:0009994 2 0.021
membrane organization GO:0061024 292 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
cell projection assembly GO:0030031 126 0.021
positive regulation of cell motility GO:2000147 177 0.021
cellular lipid metabolic process GO:0044255 303 0.021
endomembrane system organization GO:0010256 196 0.021
cellular amide metabolic process GO:0043603 69 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
innate immune response GO:0045087 178 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
metal ion transport GO:0030001 272 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
cellular ion homeostasis GO:0006873 168 0.020
positive regulation of cell differentiation GO:0045597 211 0.020
dephosphorylation GO:0016311 209 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
Mouse
positive regulation of developmental process GO:0051094 314 0.020
cardiovascular system development GO:0072358 262 0.020
cellular cation homeostasis GO:0030003 163 0.020
blastoderm segmentation GO:0007350 2 0.020
hemopoiesis GO:0030097 180 0.020
protein ubiquitination GO:0016567 314 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
Mouse
photoreceptor cell differentiation GO:0046530 2 0.020
immune system development GO:0002520 195 0.019
mitotic cell cycle GO:0000278 326 0.019
cardiac muscle cell contraction GO:0086003 4 0.019
regulation of membrane potential GO:0042391 95 0.019
positive regulation of transferase activity GO:0051347 227 0.019
Mouse
ion transmembrane transport GO:0034220 338 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.019
long term memory GO:0007616 2 0.019
positive regulation of ras gtpase activity GO:0032320 117 0.018
protein targeting to vacuole GO:0006623 8 0.018
response to lipid GO:0033993 206 0.018
protein oligomerization GO:0051259 173 0.018
regulation of cell development GO:0060284 161 0.018
Mouse
regulation of ion transport GO:0043269 189 0.018
positive regulation of synaptic transmission GO:0050806 4 0.018
negative regulation of protein binding GO:0032091 35 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
cation transmembrane transport GO:0098655 238 0.018
positive regulation of cell proliferation GO:0008284 301 0.017
neurological system process GO:0050877 163 0.017
regulation of cell projection organization GO:0031344 107 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
protein catabolic process GO:0030163 325 0.017
histone modification GO:0016570 251 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
transmembrane transport GO:0055085 399 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.017
cell chemotaxis GO:0060326 112 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
blood vessel development GO:0001568 172 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
autophagy GO:0006914 88 0.016
response to inorganic substance GO:0010035 127 0.016
regulation of amyloid precursor protein catabolic process GO:1902991 9 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
organ morphogenesis GO:0009887 147 0.016
protein localization to vacuole GO:0072665 11 0.016
spermatid differentiation GO:0048515 4 0.016
positive regulation of cytoskeleton organization GO:0051495 83 0.016
central nervous system development GO:0007417 123 0.016
neurotransmitter secretion GO:0007269 4 0.016
response to biotic stimulus GO:0009607 276 0.016
circulatory system development GO:0072359 262 0.016
regulation of cell cycle GO:0051726 393 0.016
cell division GO:0051301 168 0.016
oocyte development GO:0048599 1 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
regulation of protein complex assembly GO:0043254 147 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
circadian behavior GO:0048512 2 0.016
small molecule biosynthetic process GO:0044283 157 0.016
cellular homeostasis GO:0019725 196 0.016
regulation of protein localization GO:0032880 296 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
phospholipid metabolic process GO:0006644 99 0.016
cellular metal ion homeostasis GO:0006875 146 0.016
immune response regulating signaling pathway GO:0002764 97 0.016
chromatin modification GO:0016568 298 0.016
cellular macromolecule catabolic process GO:0044265 380 0.015
glycoprotein biosynthetic process GO:0009101 91 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
regulation of cellular response to stress GO:0080135 244 0.015
metal ion homeostasis GO:0055065 169 0.015
organic hydroxy compound metabolic process GO:1901615 147 0.015
mating GO:0007618 1 0.015
protein exit from endoplasmic reticulum GO:0032527 6 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
hematopoietic stem cell differentiation GO:0060218 4 0.015
response to peptide hormone GO:0043434 61 0.015
Human
beta amyloid metabolic process GO:0050435 12 0.015
organelle assembly GO:0070925 176 0.015
associative learning GO:0008306 1 0.015
response to wounding GO:0009611 168 0.015
epithelium development GO:0060429 227 0.015
er to golgi vesicle mediated transport GO:0006888 19 0.015
anatomical structure homeostasis GO:0060249 100 0.015
regulation of mapk cascade GO:0043408 262 0.015
Mouse
reactive nitrogen species metabolic process GO:2001057 3 0.015
sex determination GO:0007530 3 0.015
actin filament organization GO:0007015 128 0.015
cell growth GO:0016049 160 0.015
ameboidal type cell migration GO:0001667 135 0.015
inner ear morphogenesis GO:0042472 4 0.015
microtubule based process GO:0007017 210 0.014
actin filament based movement GO:0030048 17 0.014
cell part morphogenesis GO:0032990 137 0.014
positive regulation of protein exit from endoplasmic reticulum GO:0070863 4 0.014
response to metal ion GO:0010038 84 0.014
regulation of response to wounding GO:1903034 101 0.014
immune response GO:0006955 307 0.014
negative regulation of protein modification process GO:0031400 200 0.014
Mouse
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of actin filament length GO:0030832 56 0.014
tissue migration GO:0090130 119 0.014
ribonucleotide biosynthetic process GO:0009260 81 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
negative regulation of organelle organization GO:0010639 126 0.014
hindbrain development GO:0030902 3 0.014
regulation of cell adhesion GO:0030155 166 0.014
regeneration GO:0031099 4 0.014
rac protein signal transduction GO:0016601 12 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
negative regulation of synaptic transmission GO:0050805 2 0.014
regulation of defense response GO:0031347 154 0.014
vasculature development GO:0001944 181 0.014
cell substrate adhesion GO:0031589 132 0.014
plasma membrane organization GO:0007009 115 0.014
calcium ion homeostasis GO:0055074 122 0.014
cell cell signaling GO:0007267 155 0.014
regulation of actin filament based process GO:0032970 141 0.014
protein targeting GO:0006605 187 0.014
muscle contraction GO:0006936 73 0.014
purine containing compound biosynthetic process GO:0072522 88 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
response to cytokine GO:0034097 232 0.014
anterior posterior axis specification GO:0009948 2 0.014
regulation of cell projection assembly GO:0060491 47 0.013
somatic muscle development GO:0007525 1 0.013
t cell differentiation in thymus GO:0033077 4 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of growth GO:0040008 165 0.013
sequestering of metal ion GO:0051238 24 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
positive regulation of locomotion GO:0040017 186 0.013
cell cycle phase transition GO:0044770 173 0.013
salivary gland morphogenesis GO:0007435 4 0.013
sensory perception GO:0007600 103 0.013
organic acid biosynthetic process GO:0016053 97 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
carbohydrate metabolic process GO:0005975 207 0.013
regulation of endocytosis GO:0030100 72 0.013
regulation of protein kinase activity GO:0045859 289 0.013
Mouse
blood circulation GO:0008015 113 0.013
metencephalon development GO:0022037 2 0.013
atp metabolic process GO:0046034 176 0.013
visual behavior GO:0007632 2 0.013
epithelial cell migration GO:0010631 119 0.013
positive regulation of ion transport GO:0043270 87 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
sequestering of calcium ion GO:0051208 17 0.013
cardiac muscle contraction GO:0060048 34 0.013
muscle system process GO:0003012 81 0.013
embryonic epithelial tube formation GO:0001838 4 0.013
epithelium migration GO:0090132 119 0.013
regulation of anatomical structure size GO:0090066 101 0.013
neurogenesis GO:0022008 169 0.013
Mouse
activation of phospholipase d activity GO:0031584 3 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
regulation of lipase activity GO:0060191 37 0.013
Human
motor neuron axon guidance GO:0008045 2 0.013
tissue regeneration GO:0042246 3 0.013
thymus development GO:0048538 3 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
regulation of homeostatic process GO:0032844 121 0.013
ribose phosphate biosynthetic process GO:0046390 82 0.013
cell activation GO:0001775 213 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
positive regulation of cell migration GO:0030335 172 0.012
visual learning GO:0008542 1 0.012
positive regulation of proteolysis GO:0045862 142 0.012
post embryonic organ development GO:0048569 1 0.012
divalent metal ion transport GO:0070838 152 0.012
circulatory system process GO:0003013 113 0.012
negative regulation of cell cycle GO:0045786 193 0.012
cell projection morphogenesis GO:0048858 129 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
Mouse
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
retrograde transport vesicle recycling within golgi GO:0000301 3 0.012
response to decreased oxygen levels GO:0036293 96 0.012
alcohol metabolic process GO:0006066 114 0.012
cerebellum development GO:0021549 2 0.012
regulation of multi organism process GO:0043900 157 0.012
response to organic cyclic compound GO:0014070 204 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
spermatid development GO:0007286 4 0.012
regulation of response to external stimulus GO:0032101 222 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
brain development GO:0007420 97 0.012
monocarboxylic acid biosynthetic process GO:0072330 67 0.012
rna interference GO:0016246 4 0.012
angiogenesis GO:0001525 147 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
cytokine production GO:0001816 247 0.012
lysosomal transport GO:0007041 33 0.012
regulation of rho protein signal transduction GO:0035023 79 0.012
myotube differentiation GO:0014902 22 0.012
Human
head development GO:0060322 108 0.012
sensory perception of smell GO:0007608 2 0.012
cellular protein complex assembly GO:0043623 188 0.012
neuron projection development GO:0031175 106 0.012
negative regulation of transferase activity GO:0051348 124 0.012
Mouse
rna processing GO:0006396 255 0.012
mapk cascade GO:0000165 288 0.012
Mouse
response to oxygen levels GO:0070482 100 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
nucleotide biosynthetic process GO:0009165 109 0.012
response to bacterium GO:0009617 144 0.012
protein localization to plasma membrane GO:0072659 93 0.012
sensory perception of pain GO:0019233 4 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
protein polymerization GO:0051258 71 0.012
leukocyte chemotaxis GO:0030595 76 0.012
response to hypoxia GO:0001666 96 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
protein secretion GO:0009306 98 0.012
single organismal cell cell adhesion GO:0016337 148 0.012
chromatin organization GO:0006325 351 0.012
stem cell division GO:0017145 2 0.011
purine nucleotide biosynthetic process GO:0006164 84 0.011
response to fungus GO:0009620 4 0.011
forebrain generation of neurons GO:0021872 3 0.011
copulation GO:0007620 1 0.011
covalent chromatin modification GO:0016569 254 0.011
protein homooligomerization GO:0051260 100 0.011
ossification GO:0001503 121 0.011
detection of stimulus GO:0051606 85 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
cellular response to lipid GO:0071396 127 0.011
regulation of glial cell differentiation GO:0045685 3 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
regulation of protein binding GO:0043393 66 0.011
neuroblast proliferation GO:0007405 4 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
Mouse
protein import GO:0017038 130 0.011
carboxylic acid transport GO:0046942 63 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
cdc42 protein signal transduction GO:0032488 4 0.011
urea metabolic process GO:0019627 3 0.011
myoblast fusion GO:0007520 1 0.011
defense response to other organism GO:0098542 129 0.011

SORL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.080
disease of cellular proliferation DOID:14566 174 0.080
organ system cancer DOID:0050686 164 0.080
disease of metabolism DOID:0014667 295 0.039
inherited metabolic disorder DOID:655 242 0.032
central nervous system disease DOID:331 186 0.027
nervous system disease DOID:863 431 0.027
immune system disease DOID:2914 155 0.024
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
eye disease DOID:5614 149 0.023
musculoskeletal system disease DOID:17 223 0.021
gastrointestinal system cancer DOID:3119 52 0.017
neurodegenerative disease DOID:1289 102 0.015
cardiovascular system disease DOID:1287 106 0.014
connective tissue disease DOID:65 109 0.013
retinal disease DOID:5679 118 0.013