Homo sapiens

104 known processes

SORT1

sortilin 1

(Aliases: NT3,Gp95,LDLCQ6)

SORT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of lipoprotein lipase activity GO:0051004 12 0.852
protein localization to early endosome GO:1902946 2 0.803
Human
nerve growth factor signaling pathway GO:0038180 4 0.747
plasma membrane to endosome transport GO:0048227 6 0.636
post golgi vesicle mediated transport GO:0006892 36 0.589
endosome to lysosome transport GO:0008333 21 0.530
negative regulation of cellular amide metabolic process GO:0034249 3 0.411
Human
regulation of protein localization to early endosome GO:1902965 2 0.382
Human
positive regulation of protein localization to early endosome GO:1902966 2 0.368
Human
negative regulation of amyloid precursor protein catabolic process GO:1902992 4 0.306
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.297
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.292
protein localization to lysosome GO:0061462 11 0.228
Human
establishment of protein localization to organelle GO:0072594 172 0.216
Human
response to nerve growth factor GO:1990089 6 0.208
intracellular protein transport GO:0006886 270 0.190
Human
neurotrophin trk receptor signaling pathway GO:0048011 4 0.189
ribonucleoside catabolic process GO:0042454 406 0.187
positive regulation of catabolic process GO:0009896 310 0.183
Human
ras protein signal transduction GO:0007265 73 0.170
purine nucleoside triphosphate metabolic process GO:0009144 412 0.168
regulation of kinase activity GO:0043549 314 0.165
response to oxygen containing compound GO:1901700 369 0.157
regulation of amyloid precursor protein catabolic process GO:1902991 9 0.153
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.151
negative regulation of protein processing GO:0010955 142 0.151
Human
muscle cell migration GO:0014812 19 0.149
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.149
positive regulation of protein catabolic process GO:0045732 75 0.144
Human
beta amyloid formation GO:0034205 7 0.143
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.140
negative regulation of protein metabolic process GO:0051248 391 0.140
Human
negative regulation of cellular component organization GO:0051129 235 0.136
Human
positive regulation of transferase activity GO:0051347 227 0.135
purine ribonucleoside catabolic process GO:0046130 398 0.134
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.133
regulation of locomotion GO:0040012 329 0.132
Human
vacuolar transport GO:0007034 34 0.131
negative regulation of catalytic activity GO:0043086 335 0.129
purine nucleotide catabolic process GO:0006195 405 0.126
negative regulation of cellular protein metabolic process GO:0032269 353 0.123
Human
regulation of protein transport GO:0051223 213 0.120
Human
regulation of establishment of protein localization GO:0070201 242 0.118
Human
protein maturation GO:0051604 233 0.116
Human
negative regulation of peptidase activity GO:0010466 91 0.112
Human
signal transduction by phosphorylation GO:0023014 297 0.110
purine ribonucleotide catabolic process GO:0009154 404 0.109
negative regulation of beta amyloid formation GO:1902430 3 0.109
Human
regulation of peptidase activity GO:0052547 180 0.109
Human
regulation of cellular component biogenesis GO:0044087 281 0.105
Human
regulation of proteolysis GO:0030162 293 0.104
Human
apoptotic signaling pathway GO:0097190 268 0.103
secretion GO:0046903 254 0.103
regulation of cell motility GO:2000145 299 0.100
Human
vesicle mediated transport GO:0016192 371 0.099
regulation of protein maturation GO:1903317 150 0.099
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.099
regulation of transferase activity GO:0051338 355 0.096
response to growth factor GO:0070848 205 0.094
small gtpase mediated signal transduction GO:0007264 78 0.094
protein localization to vacuole GO:0072665 11 0.094
Human
regulation of cytoplasmic transport GO:1903649 149 0.092
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.091
glucose transport GO:0015758 30 0.091
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.088
nucleoside catabolic process GO:0009164 408 0.087
nucleoside triphosphate catabolic process GO:0009143 394 0.087
cellular amino acid metabolic process GO:0006520 116 0.086
negative regulation of proteolysis GO:0045861 132 0.084
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.083
negative regulation of hydrolase activity GO:0051346 182 0.083
protein processing GO:0016485 226 0.083
Human
mapk cascade GO:0000165 288 0.082
protein targeting to golgi GO:0000042 3 0.080
Human
negative regulation of cell death GO:0060548 345 0.079
regulation of nucleotide metabolic process GO:0006140 269 0.078
endocytic recycling GO:0032456 12 0.077
Human
purine nucleoside catabolic process GO:0006152 398 0.077
negative regulation of lipoprotein lipase activity GO:0051005 5 0.076
monosaccharide transport GO:0015749 32 0.075
peptide metabolic process GO:0006518 51 0.074
Human
macromolecule glycosylation GO:0043413 63 0.073
positive regulation of hydrolase activity GO:0051345 331 0.073
protein localization to organelle GO:0033365 280 0.072
Human
amyloid precursor protein metabolic process GO:0042982 17 0.072
Human
glycosyl compound catabolic process GO:1901658 413 0.071
regulation of protein kinase activity GO:0045859 289 0.071
positive regulation of protein transport GO:0051222 135 0.069
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.068
endosomal transport GO:0016197 129 0.067
maintenance of protein location in cell GO:0032507 56 0.066
Human
purine ribonucleoside metabolic process GO:0046128 437 0.065
regulation of cell development GO:0060284 161 0.064
cellular response to growth factor stimulus GO:0071363 197 0.064
negative regulation of endopeptidase activity GO:0010951 84 0.064
Human
amine metabolic process GO:0009308 44 0.063
negative regulation of cell differentiation GO:0045596 171 0.062
intra golgi vesicle mediated transport GO:0006891 8 0.062
Human
nucleoside phosphate catabolic process GO:1901292 412 0.062
inclusion body assembly GO:0070841 17 0.061
protein catabolic process GO:0030163 325 0.061
Human
negative regulation of protein modification process GO:0031400 200 0.060
glycoprotein metabolic process GO:0009100 110 0.060
amyloid precursor protein catabolic process GO:0042987 12 0.059
Human
gtp metabolic process GO:0046039 239 0.059
glucose import GO:0046323 24 0.059
cellular ketone metabolic process GO:0042180 80 0.058
regulation of cell differentiation GO:0045595 393 0.058
golgi vesicle transport GO:0048193 80 0.057
protein targeting to vacuole GO:0006623 8 0.056
Human
chemical homeostasis GO:0048878 306 0.056
cellular amine metabolic process GO:0044106 41 0.055
protein glycosylation GO:0006486 62 0.055
regulation of vesicle mediated transport GO:0060627 130 0.055
Human
post embryonic development GO:0009791 2 0.055
regulation of cellular amine metabolic process GO:0033238 11 0.055
regulation of map kinase activity GO:0043405 108 0.054
negative regulation of multicellular organismal process GO:0051241 317 0.053
protein oligomerization GO:0051259 173 0.053
Human
single organism carbohydrate metabolic process GO:0044723 193 0.053
regulation of protein catabolic process GO:0042176 155 0.053
Human
response to peptide GO:1901652 65 0.053
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.052
g protein coupled receptor signaling pathway GO:0007186 207 0.052
negative regulation of inclusion body assembly GO:0090084 9 0.051
female gamete generation GO:0007292 2 0.050
regulation of gtp catabolic process GO:0033124 180 0.049
cellular macromolecular complex assembly GO:0034622 324 0.049
regulation of cell migration GO:0030334 289 0.049
Human
extrinsic apoptotic signaling pathway GO:0097191 119 0.048
single organism membrane organization GO:0044802 268 0.048
positive regulation of cellular amine metabolic process GO:0033240 7 0.048
secretion by cell GO:0032940 226 0.048
nucleotide catabolic process GO:0009166 408 0.047
regulation of nervous system development GO:0051960 88 0.047
regulation of mapk cascade GO:0043408 262 0.046
regulation of ras protein signal transduction GO:0046578 155 0.046
positive regulation of transport GO:0051050 336 0.046
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.046
regulation of cellular ketone metabolic process GO:0010565 50 0.044
positive regulation of intracellular transport GO:0032388 104 0.044
Human
response to organonitrogen compound GO:0010243 156 0.043
regulation of inclusion body assembly GO:0090083 13 0.043
negative regulation of protein phosphorylation GO:0001933 140 0.043
response to nitrogen compound GO:1901698 184 0.042
regulation of anatomical structure morphogenesis GO:0022603 286 0.042
positive regulation of cytoplasmic transport GO:1903651 82 0.041
Human
regulation of beta amyloid formation GO:1902003 7 0.041
Human
negative regulation of protein oligomerization GO:0032460 8 0.040
Human
establishment of protein localization to golgi GO:0072600 4 0.040
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.040
lipid metabolic process GO:0006629 381 0.040
regulation of synaptic plasticity GO:0048167 3 0.039
maintenance of location in cell GO:0051651 62 0.038
Human
guanosine containing compound catabolic process GO:1901069 239 0.037
er to golgi vesicle mediated transport GO:0006888 19 0.037
Human
maintenance of location GO:0051235 112 0.037
Human
guanosine containing compound metabolic process GO:1901068 244 0.037
negative regulation of protein maturation GO:1903318 142 0.036
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.036
negative regulation of mapk cascade GO:0043409 56 0.036
purine containing compound catabolic process GO:0072523 411 0.035
organophosphate catabolic process GO:0046434 430 0.035
regulation of intracellular transport GO:0032386 195 0.034
Human
cation transport GO:0006812 331 0.034
cell morphogenesis GO:0000902 296 0.034
maintenance of protein location GO:0045185 57 0.034
Human
negative regulation of transferase activity GO:0051348 124 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
neuron death GO:0070997 65 0.033
generation of neurons GO:0048699 152 0.033
regulation of protein processing GO:0070613 150 0.033
Human
negative regulation of protein complex assembly GO:0031333 43 0.033
Human
nervous system development GO:0007399 293 0.033
determination of adult lifespan GO:0008340 2 0.033
negative regulation of developmental process GO:0051093 247 0.033
ion homeostasis GO:0050801 230 0.033
negative regulation of phosphorylation GO:0042326 174 0.032
regulation of nucleotide catabolic process GO:0030811 205 0.032
negative regulation of map kinase activity GO:0043407 27 0.032
cell adhesion GO:0007155 325 0.032
oogenesis GO:0048477 2 0.032
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
smooth muscle cell migration GO:0014909 18 0.031
Human
cation homeostasis GO:0055080 189 0.031
negative regulation of binding GO:0051100 57 0.031
Human
cellular chemical homeostasis GO:0055082 180 0.031
carbohydrate metabolic process GO:0005975 207 0.031
cell projection organization GO:0030030 252 0.030
regulation of neuron death GO:1901214 56 0.030
negative regulation of programmed cell death GO:0043069 321 0.029
positive regulation of organelle organization GO:0010638 195 0.029
actin filament based process GO:0030029 224 0.029
cell development GO:0048468 328 0.028
neurotransmitter secretion GO:0007269 4 0.028
single organism cellular localization GO:1902580 332 0.028
Human
vesicle organization GO:0016050 62 0.028
positive regulation of nucleotide metabolic process GO:0045981 230 0.028
carbohydrate derivative biosynthetic process GO:1901137 207 0.028
protein modification by small protein conjugation GO:0032446 342 0.028
positive regulation of cellular component organization GO:0051130 376 0.027
organonitrogen compound biosynthetic process GO:1901566 200 0.027
positive regulation of gtpase activity GO:0043547 166 0.027
ion transmembrane transport GO:0034220 338 0.027
dephosphorylation GO:0016311 209 0.027
negative regulation of protein kinase activity GO:0006469 98 0.027
negative regulation of cellular amine metabolic process GO:0033239 3 0.027
multicellular organismal aging GO:0010259 3 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
ribonucleotide catabolic process GO:0009261 405 0.026
neuromuscular junction development GO:0007528 3 0.026
regulation of cytoskeleton organization GO:0051493 177 0.026
rho protein signal transduction GO:0007266 26 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
actin cytoskeleton organization GO:0030036 207 0.025
reactive oxygen species metabolic process GO:0072593 75 0.025
gtp catabolic process GO:0006184 237 0.025
muscle cell differentiation GO:0042692 63 0.025
toxin transport GO:1901998 4 0.025
glycosylation GO:0070085 71 0.025
regulation of ras gtpase activity GO:0032318 128 0.025
positive regulation of cell proliferation GO:0008284 301 0.024
cellular metal ion homeostasis GO:0006875 146 0.024
oocyte differentiation GO:0009994 2 0.024
biological adhesion GO:0022610 331 0.023
cellular component morphogenesis GO:0032989 314 0.023
negative regulation of protein binding GO:0032091 35 0.023
Human
anion transport GO:0006820 161 0.023
memory GO:0007613 3 0.023
cellular amide metabolic process GO:0043603 69 0.023
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
beta amyloid metabolic process GO:0050435 12 0.023
Human
metal ion transport GO:0030001 272 0.023
carbohydrate transport GO:0008643 37 0.022
cellular ion homeostasis GO:0006873 168 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
hemopoiesis GO:0030097 180 0.022
endocytosis GO:0006897 159 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
positive regulation of ras gtpase activity GO:0032320 117 0.021
immune system development GO:0002520 195 0.021
sensory perception of pain GO:0019233 4 0.021
regulation of ion transport GO:0043269 189 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
response to abiotic stimulus GO:0009628 336 0.021
negative regulation of kinase activity GO:0033673 106 0.021
organic acid biosynthetic process GO:0016053 97 0.020
neurogenesis GO:0022008 169 0.020
locomotory behavior GO:0007626 1 0.020
cellular cation homeostasis GO:0030003 163 0.020
cell division GO:0051301 168 0.020
endomembrane system organization GO:0010256 196 0.020
establishment of protein localization to vacuole GO:0072666 8 0.020
Human
positive regulation of synaptic transmission GO:0050806 4 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
regulation of actin filament based process GO:0032970 141 0.020
mitotic cell cycle GO:0000278 326 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
small molecule biosynthetic process GO:0044283 157 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.019
response to hormone GO:0009725 175 0.019
regeneration GO:0031099 4 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
membrane organization GO:0061024 292 0.019
regulation of actin cytoskeleton organization GO:0032956 116 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
Human
positive regulation of cell differentiation GO:0045597 211 0.019
system process GO:0003008 349 0.019
muscle structure development GO:0061061 98 0.019
response to axon injury GO:0048678 1 0.019
glycerolipid metabolic process GO:0046486 107 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.018
cell cell signaling GO:0007267 155 0.018
sequestering of calcium ion GO:0051208 17 0.018
regulation of neurotransmitter secretion GO:0046928 3 0.018
oocyte development GO:0048599 1 0.018
enzyme linked receptor protein signaling pathway GO:0007167 303 0.018
neuronal stem cell division GO:0036445 1 0.018
stem cell division GO:0017145 2 0.018
peripheral nervous system development GO:0007422 2 0.018
cardiac muscle cell contraction GO:0086003 4 0.018
blastoderm segmentation GO:0007350 2 0.018
regulation of reactive oxygen species metabolic process GO:2000377 41 0.018
spermatid differentiation GO:0048515 4 0.018
positive regulation of cytoskeleton organization GO:0051495 83 0.018
transmembrane transport GO:0055085 399 0.018
regulation of gtpase activity GO:0043087 180 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
regulation of cellular component movement GO:0051270 334 0.017
Human
protein ubiquitination GO:0016567 314 0.017
chromatin modification GO:0016568 298 0.017
atp metabolic process GO:0046034 176 0.017
lysosomal transport GO:0007041 33 0.017
cellular lipid metabolic process GO:0044255 303 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
neuroblast proliferation GO:0007405 4 0.017
atp catabolic process GO:0006200 157 0.017
regulation of neurogenesis GO:0050767 82 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
cellular homeostasis GO:0019725 196 0.016
cell projection assembly GO:0030031 126 0.016
somatic stem cell division GO:0048103 1 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
metal ion homeostasis GO:0055065 169 0.016
synaptic transmission GO:0007268 61 0.016
chemotaxis GO:0006935 157 0.016
regulation of chemotaxis GO:0050920 74 0.016
microtubule based process GO:0007017 210 0.016
regulation of metal ion transport GO:0010959 120 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
cation transmembrane transport GO:0098655 238 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
sequestering of metal ion GO:0051238 24 0.015
nitrogen compound transport GO:0071705 191 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
anterior posterior axis specification GO:0009948 2 0.015
positive regulation of kinase activity GO:0033674 204 0.015
cell growth GO:0016049 160 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
developmental programmed cell death GO:0010623 3 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
response to fungus GO:0009620 4 0.015
protein targeting to lysosome GO:0006622 8 0.015
Human
monovalent inorganic cation transport GO:0015672 128 0.015
regulation of cellular response to growth factor stimulus GO:0090287 76 0.015
taxis GO:0042330 157 0.015
long term memory GO:0007616 2 0.015
regulation of receptor mediated endocytosis GO:0048259 32 0.015
actin mediated cell contraction GO:0070252 12 0.014
phospholipid metabolic process GO:0006644 99 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
peptidyl serine modification GO:0018209 106 0.014
positive regulation of cell death GO:0010942 263 0.014
adult locomotory behavior GO:0008344 1 0.014
positive regulation of cell motility GO:2000147 177 0.014
regulation of cellular response to stress GO:0080135 244 0.014
monocarboxylic acid biosynthetic process GO:0072330 67 0.014
organ formation GO:0048645 3 0.014
regulation of protein complex assembly GO:0043254 147 0.014
Human
alcohol metabolic process GO:0006066 114 0.014
sensory perception GO:0007600 103 0.014
regulation of cell projection organization GO:0031344 107 0.014
positive regulation of neural precursor cell proliferation GO:2000179 2 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
plasma membrane organization GO:0007009 115 0.014
protein targeting GO:0006605 187 0.014
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
urea metabolic process GO:0019627 3 0.014
rac protein signal transduction GO:0016601 12 0.014
regulation of homeostatic process GO:0032844 121 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
actin filament organization GO:0007015 128 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
retrograde transport vesicle recycling within golgi GO:0000301 3 0.014
Human
reactive oxygen species biosynthetic process GO:1903409 4 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
cell part morphogenesis GO:0032990 137 0.013
cofactor metabolic process GO:0051186 87 0.013
regulation of cell adhesion GO:0030155 166 0.013
cardiovascular system development GO:0072358 262 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
hematopoietic stem cell differentiation GO:0060218 4 0.013
response to inorganic substance GO:0010035 127 0.013
asymmetric neuroblast division GO:0055059 1 0.013
negative regulation of neuron death GO:1901215 32 0.013
axon cargo transport GO:0008088 2 0.013
circulatory system development GO:0072359 262 0.013
vasculature development GO:0001944 181 0.013
regulation of endocytosis GO:0030100 72 0.013
mating GO:0007618 1 0.013
rab protein signal transduction GO:0032482 4 0.013
motor neuron axon guidance GO:0008045 2 0.013
regulation of dephosphorylation GO:0035303 96 0.013
hindbrain development GO:0030902 3 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
positive regulation of behavior GO:0048520 60 0.013
regulation of growth GO:0040008 165 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
divalent metal ion transport GO:0070838 152 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
ribonucleoside monophosphate catabolic process GO:0009158 158 0.013
visual behavior GO:0007632 2 0.013
cardiac muscle contraction GO:0060048 34 0.013
histone modification GO:0016570 251 0.013
circadian behavior GO:0048512 2 0.013
neuroblast division GO:0055057 1 0.013
regulation of response to external stimulus GO:0032101 222 0.013
golgi to endosome transport GO:0006895 7 0.013
asymmetric stem cell division GO:0098722 1 0.013
calcium ion transmembrane transport GO:0070588 76 0.013
glycerophospholipid metabolic process GO:0006650 84 0.013
neuron differentiation GO:0030182 138 0.013
regulation of cytokine production GO:0001817 232 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
response to external biotic stimulus GO:0043207 261 0.013
salivary gland morphogenesis GO:0007435 4 0.013
cellular protein complex assembly GO:0043623 188 0.012
sulfur compound metabolic process GO:0006790 101 0.012
positive regulation of protein exit from endoplasmic reticulum GO:0070863 4 0.012
Human
activation of protein kinase activity GO:0032147 90 0.012
striated muscle contraction GO:0006941 52 0.012
rhythmic behavior GO:0007622 2 0.012
inner ear morphogenesis GO:0042472 4 0.012
protein autophosphorylation GO:0046777 123 0.012
neuron development GO:0048666 113 0.012
regulation of plasma lipoprotein particle levels GO:0097006 32 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
regulation of protein localization GO:0032880 296 0.012
Human
collateral sprouting GO:0048668 2 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
actin filament polymerization GO:0030041 45 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
spermatid development GO:0007286 4 0.012
establishment of planar polarity GO:0001736 3 0.012
cell projection morphogenesis GO:0048858 129 0.012
epithelial cell differentiation GO:0030855 141 0.012
cell cycle phase transition GO:0044770 173 0.012
rna interference GO:0016246 4 0.012
small molecule catabolic process GO:0044282 92 0.012
thymus development GO:0048538 3 0.012
regulation of exocytosis GO:0017157 46 0.012
autophagy GO:0006914 88 0.012
tripartite regional subdivision GO:0007351 2 0.012
negative regulation of nervous system development GO:0051961 28 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
regulation of phosphatase activity GO:0010921 81 0.011
copper ion homeostasis GO:0055070 3 0.011
positive regulation of collateral sprouting GO:0048672 2 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
defense response GO:0006952 315 0.011
compound eye development GO:0048749 1 0.011
epidermis morphogenesis GO:0048730 3 0.011
protein localization to plasma membrane GO:0072659 93 0.011
organ morphogenesis GO:0009887 147 0.011
organelle assembly GO:0070925 176 0.011
dicarboxylic acid biosynthetic process GO:0043650 4 0.011
regulation of lipase activity GO:0060191 37 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
positive regulation of developmental process GO:0051094 314 0.011
regulation of angiogenesis GO:0045765 92 0.011
regulation of peptidyl serine phosphorylation GO:0033135 50 0.011
rna processing GO:0006396 255 0.011
regulation of ion transmembrane transport GO:0034765 132 0.011
associative learning GO:0008306 1 0.011
l amino acid import GO:0043092 4 0.011
nucleus localization GO:0051647 1 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
regulation of anatomical structure size GO:0090066 101 0.011
negative regulation of catabolic process GO:0009895 104 0.011
regulation of secretion GO:0051046 194 0.011
tissue regeneration GO:0042246 3 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
muscle contraction GO:0006936 73 0.011
somatic muscle development GO:0007525 1 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
organic anion transport GO:0015711 103 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011

SORT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.385
Human
nervous system disease DOID:863 431 0.385
Human
tauopathy DOID:680 16 0.270
Human
neurodegenerative disease DOID:1289 102 0.270
Human
cancer DOID:162 167 0.113
disease of cellular proliferation DOID:14566 174 0.113
organ system cancer DOID:0050686 164 0.113
disease of mental health DOID:150 70 0.094
Human
cognitive disorder DOID:1561 29 0.094
Human
dementia DOID:1307 19 0.049
Human
alzheimer s disease DOID:10652 16 0.049
Human
disease of metabolism DOID:0014667 295 0.041
gastrointestinal system cancer DOID:3119 52 0.040
inherited metabolic disorder DOID:655 242 0.030
muscular disease DOID:0080000 114 0.019
musculoskeletal system disease DOID:17 223 0.019
muscle tissue disease DOID:66 113 0.019
neuropathy DOID:870 52 0.017
cardiovascular system disease DOID:1287 106 0.017
myopathy DOID:423 104 0.016
immune system disease DOID:2914 155 0.016
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
retinal disease DOID:5679 118 0.011