Homo sapiens

97 known processes

SPEN

spen homolog, transcriptional regulator (Drosophila)

(Aliases: KIAA0929,HIAA0929,MINT,RBM15C,SHARP)

SPEN biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 1.000
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003256 3 0.988
secondary heart field specification GO:0003139 2 0.945
nephric duct development GO:0072176 4 0.929
cardiac muscle cell fate commitment GO:0060923 4 0.853
regulation of wnt signaling pathway involved in heart development GO:0003307 3 0.841
positive regulation of cardiac muscle cell proliferation GO:0060045 2 0.803
chromatin organization GO:0006325 351 0.777
chromatin modification GO:0016568 298 0.764
positive regulation of cardiac muscle cell differentiation GO:2000727 4 0.757
heart formation GO:0060914 2 0.744
ventricular trabecula myocardium morphogenesis GO:0003222 1 0.733
glomerular visceral epithelial cell differentiation GO:0072112 4 0.631
regulation of heart morphogenesis GO:2000826 4 0.612
cardiovascular system development GO:0072358 262 0.597
segmentation GO:0035282 4 0.574
Fly
cellular component morphogenesis GO:0032989 314 0.572
Fly
covalent chromatin modification GO:0016569 254 0.545
regulation of cell differentiation GO:0045595 393 0.537
regulation of cell cycle process GO:0010564 266 0.491
regulation of cardiac muscle cell differentiation GO:2000725 7 0.485
specification of organ identity GO:0010092 3 0.466
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.450
Fly
cardiac left ventricle morphogenesis GO:0003214 6 0.449
regulation of cell cycle GO:0051726 393 0.442
heart field specification GO:0003128 2 0.439
lung cell differentiation GO:0060479 1 0.424
blastoderm segmentation GO:0007350 2 0.401
histone modification GO:0016570 251 0.397
long term memory GO:0007616 2 0.393
cardiac muscle cell myoblast differentiation GO:0060379 5 0.383
growth GO:0040007 202 0.358
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.353
positive regulation of developmental process GO:0051094 314 0.344
organ formation GO:0048645 3 0.343
female gamete generation GO:0007292 2 0.326
glial cell migration GO:0008347 4 0.323
Fly
pituitary gland development GO:0021983 2 0.307
blood vessel morphogenesis GO:0048514 162 0.297
regulation of mitotic cell cycle GO:0007346 189 0.297
lung epithelial cell differentiation GO:0060487 1 0.287
memory GO:0007613 3 0.282
cell activation GO:0001775 213 0.263
hair follicle maturation GO:0048820 3 0.262
sebaceous gland development GO:0048733 1 0.261
wnt signaling pathway GO:0016055 156 0.260
Fly
somatic stem cell maintenance GO:0035019 4 0.252
blood vessel development GO:0001568 172 0.242
enzyme linked receptor protein signaling pathway GO:0007167 303 0.240
Fly
post embryonic development GO:0009791 2 0.236
Fly
organ morphogenesis GO:0009887 147 0.231
Fly
regulation of mitotic cell cycle phase transition GO:1901990 118 0.224
cardiac conduction system development GO:0003161 2 0.223
i kappab phosphorylation GO:0007252 7 0.221
cell development GO:0048468 328 0.211
pronephric nephron development GO:0039019 1 0.207
hair cell differentiation GO:0035315 2 0.200
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.200
somitogenesis GO:0001756 2 0.190
positive regulation of cell proliferation GO:0008284 301 0.187
regulation of heart growth GO:0060420 4 0.182
generation of neurons GO:0048699 152 0.179
regulation of anatomical structure morphogenesis GO:0022603 286 0.179
positive regulation of muscle cell differentiation GO:0051149 15 0.178
myeloid dendritic cell differentiation GO:0043011 3 0.177
oogenesis GO:0048477 2 0.172
response to oxygen containing compound GO:1901700 369 0.164
cell cycle phase transition GO:0044770 173 0.164
regulation of cardiac muscle cell proliferation GO:0060043 4 0.163
aortic valve development GO:0003176 3 0.163
embryonic placenta development GO:0001892 1 0.157
vasculature development GO:0001944 181 0.156
circulatory system development GO:0072359 262 0.156
mitotic cell cycle phase transition GO:0044772 162 0.153
lung epithelium development GO:0060428 7 0.152
endocardial cushion development GO:0003197 3 0.151
positive regulation of striated muscle cell differentiation GO:0051155 9 0.147
mitotic cell cycle GO:0000278 326 0.146
defense response GO:0006952 315 0.144
Fly
regulation of cell proliferation involved in heart morphogenesis GO:2000136 1 0.143
mrna metabolic process GO:0016071 175 0.142
Human
system process GO:0003008 349 0.140
epithelial cell fate commitment GO:0072148 3 0.139
positive regulation of mitotic cell cycle GO:0045931 60 0.139
neuron differentiation GO:0030182 138 0.136
Fly
myeloid cell differentiation GO:0030099 117 0.134
epithelium development GO:0060429 227 0.134
Fly
positive regulation of cardiac muscle tissue growth GO:0055023 2 0.131
pronephros development GO:0048793 2 0.131
cardiac right ventricle formation GO:0003219 1 0.130
positive regulation of cell fate commitment GO:0010455 2 0.129
notch signaling pathway GO:0007219 31 0.129
response to external biotic stimulus GO:0043207 261 0.129
Fly
heart development GO:0007507 95 0.128
hair cycle GO:0042633 28 0.128
aorta morphogenesis GO:0035909 1 0.127
negative regulation of transport GO:0051051 176 0.125
behavior GO:0007610 112 0.125
positive regulation of cell cycle process GO:0090068 106 0.124
tube morphogenesis GO:0035239 95 0.123
regulation of cellular amine metabolic process GO:0033238 11 0.121
positive regulation of organ growth GO:0046622 2 0.121
nervous system development GO:0007399 293 0.120
i kappab kinase nf kappab signaling GO:0007249 166 0.119
cardiac right ventricle morphogenesis GO:0003215 3 0.119
spinal cord development GO:0021510 4 0.117
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.115
organelle fission GO:0048285 149 0.115
aortic valve morphogenesis GO:0003180 3 0.115
myeloid dendritic cell activation GO:0001773 4 0.114
cellular response to dna damage stimulus GO:0006974 379 0.114
neurological system process GO:0050877 163 0.112
cardiac muscle cell differentiation GO:0055007 15 0.106
tube development GO:0035295 125 0.103
g1 s transition of mitotic cell cycle GO:0000082 78 0.102
regulation of cellular amino acid metabolic process GO:0006521 6 0.101
cell morphogenesis GO:0000902 296 0.101
Fly
cell projection organization GO:0030030 252 0.100
Fly
cardiac ventricle formation GO:0003211 2 0.100
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.099
glomerular epithelial cell differentiation GO:0072311 5 0.099
methylation GO:0032259 106 0.097
negative regulation of multicellular organismal process GO:0051241 317 0.095
angiogenesis GO:0001525 147 0.094
regulation of cell division GO:0051302 116 0.094
hematopoietic or lymphoid organ development GO:0048534 186 0.092
cardiac muscle tissue development GO:0048738 39 0.092
regulation of cell cycle g1 s phase transition GO:1902806 42 0.092
bmp signaling pathway GO:0030509 49 0.090
cell morphogenesis involved in differentiation GO:0000904 144 0.090
Fly
negative regulation of apoptotic process GO:0043066 316 0.090
protein dna complex subunit organization GO:0071824 80 0.088
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.088
ephrin receptor signaling pathway GO:0048013 15 0.088
mesodermal cell fate specification GO:0007501 2 0.087
inflammatory response GO:0006954 79 0.087
regulation of cell cycle phase transition GO:1901987 126 0.087
central nervous system development GO:0007417 123 0.086
forebrain development GO:0030900 26 0.085
anatomical structure maturation GO:0071695 9 0.085
internal protein amino acid acetylation GO:0006475 101 0.084
regulation of small gtpase mediated signal transduction GO:0051056 156 0.084
histone lysine methylation GO:0034968 50 0.084
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 6 0.083
neural tube formation GO:0001841 3 0.082
mapk cascade GO:0000165 288 0.081
cellular response to organic cyclic compound GO:0071407 127 0.080
humoral immune response GO:0006959 49 0.080
cell cycle g1 s phase transition GO:0044843 80 0.079
embryo development GO:0009790 123 0.079
regulation of response to external stimulus GO:0032101 222 0.079
pericardium development GO:0060039 2 0.079
positive regulation of wnt signaling pathway GO:0030177 54 0.078
Fly
keratinocyte differentiation GO:0030216 36 0.078
immune response GO:0006955 307 0.078
intracellular protein transport GO:0006886 270 0.077
determination of adult lifespan GO:0008340 2 0.077
negative regulation of cell proliferation GO:0008285 228 0.076
regulation of meiosis GO:0040020 3 0.075
regulation of bmp signaling pathway GO:0030510 27 0.074
neurogenesis GO:0022008 169 0.074
peptidyl lysine acetylation GO:0018394 101 0.072
negative regulation of endothelial cell chemotaxis GO:2001027 4 0.071
chemotaxis GO:0006935 157 0.071
Fly
glomerular epithelium development GO:0072010 7 0.071
response to biotic stimulus GO:0009607 276 0.070
Fly
heart trabecula morphogenesis GO:0061384 1 0.070
negative regulation of cell death GO:0060548 345 0.070
amine metabolic process GO:0009308 44 0.070
cytoplasmic transport GO:0016482 379 0.069
histone acetylation GO:0016573 93 0.069
negative regulation of chromatin silencing GO:0031936 4 0.069
cellular amine metabolic process GO:0044106 41 0.068
hemopoiesis GO:0030097 180 0.068
defense response to bacterium GO:0042742 63 0.065
defense response to other organism GO:0098542 129 0.064
Fly
negative regulation of cell differentiation GO:0045596 171 0.063
positive regulation of cell cycle GO:0045787 140 0.063
cellular ketone metabolic process GO:0042180 80 0.062
cell division GO:0051301 168 0.062
glomerulus development GO:0032835 15 0.061
response to bacterium GO:0009617 144 0.061
endocardium development GO:0003157 2 0.061
mitral valve development GO:0003174 3 0.061
reproductive process GO:0022414 106 0.061
histone h3 acetylation GO:0043966 45 0.061
response to lipid GO:0033993 206 0.061
neuron fate commitment GO:0048663 2 0.060
secretion by cell GO:0032940 226 0.060
positive regulation of jak stat cascade GO:0046427 35 0.059
secretion GO:0046903 254 0.059
regulation of nuclear division GO:0051783 65 0.059
regulation of ossification GO:0030278 58 0.059
leukocyte differentiation GO:0002521 98 0.058
blood vessel remodeling GO:0001974 2 0.058
heart morphogenesis GO:0003007 48 0.057
negative regulation of gliogenesis GO:0014014 3 0.057
vesicle mediated transport GO:0016192 371 0.057
neuromuscular junction development GO:0007528 3 0.056
regulation of growth GO:0040008 165 0.056
respiratory tube development GO:0030323 20 0.055
neuroblast proliferation GO:0007405 4 0.055
epithelial cell differentiation involved in kidney development GO:0035850 9 0.055
immune system development GO:0002520 195 0.055
cellular amino acid metabolic process GO:0006520 116 0.054
negative regulation of programmed cell death GO:0043069 321 0.054
myeloid leukocyte differentiation GO:0002573 60 0.054
cytokine production GO:0001816 247 0.053
adult locomotory behavior GO:0008344 1 0.053
mrna processing GO:0006397 133 0.052
Human
nucleocytoplasmic transport GO:0006913 176 0.052
nucleosome organization GO:0034728 66 0.052
cellular response to oxygen containing compound GO:1901701 276 0.051
photoreceptor cell differentiation GO:0046530 2 0.051
response to growth factor GO:0070848 205 0.051
pattern specification process GO:0007389 43 0.051
Fly
cellular macromolecular complex assembly GO:0034622 324 0.050
cell fate commitment involved in pattern specification GO:0060581 1 0.050
ras protein signal transduction GO:0007265 73 0.050
synaptic transmission GO:0007268 61 0.050
cognition GO:0050890 43 0.050
peptidyl lysine modification GO:0018205 144 0.049
associative learning GO:0008306 1 0.049
regulation of muscle cell differentiation GO:0051147 31 0.049
visual learning GO:0008542 1 0.049
regulation of gene expression epigenetic GO:0040029 73 0.049
wnt signaling pathway involved in heart development GO:0003306 5 0.049
regulation of cellular ketone metabolic process GO:0010565 50 0.048
locomotory behavior GO:0007626 1 0.048
multicellular organismal aging GO:0010259 3 0.047
dna repair GO:0006281 198 0.047
ossification GO:0001503 121 0.047
positive regulation of cell differentiation GO:0045597 211 0.047
coronary vasculature development GO:0060976 2 0.047
cardiac chamber formation GO:0003207 2 0.047
regulation of pro b cell differentiation GO:2000973 1 0.047
epithelial cell differentiation GO:0030855 141 0.046
Fly
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.046
negative regulation of phosphate metabolic process GO:0045936 267 0.046
lateral mesoderm development GO:0048368 1 0.046
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.045
neuron projection development GO:0031175 106 0.045
Fly
microtubule based process GO:0007017 210 0.045
cerebellum development GO:0021549 2 0.045
endothelial cell fate commitment GO:0060839 3 0.044
histone h3 k27 demethylation GO:0071557 3 0.044
b cell activation GO:0042113 33 0.044
signal transduction by phosphorylation GO:0023014 297 0.044
anatomical structure formation involved in morphogenesis GO:0048646 284 0.044
positive regulation of heart growth GO:0060421 2 0.043
renal filtration cell differentiation GO:0061318 4 0.043
negative regulation of secretion by cell GO:1903531 52 0.042
cardiocyte differentiation GO:0035051 23 0.042
chordate embryonic development GO:0043009 34 0.042
biological adhesion GO:0022610 331 0.042
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.041
positive regulation of cellular component organization GO:0051130 376 0.041
regulation of wnt signaling pathway GO:0030111 123 0.041
Fly
canonical wnt signaling pathway GO:0060070 116 0.041
negative regulation of intracellular signal transduction GO:1902532 183 0.041
cell fate determination GO:0001709 3 0.041
Fly
protein ubiquitination GO:0016567 314 0.040
epidermal cell differentiation GO:0009913 45 0.040
Fly
stem cell division GO:0017145 2 0.040
positive regulation of cellular amine metabolic process GO:0033240 7 0.039
negative regulation of ossification GO:0030279 21 0.039
embryonic organ development GO:0048568 36 0.039
skeletal system development GO:0001501 79 0.039
stem cell development GO:0048864 69 0.039
mesodermal cell fate commitment GO:0001710 2 0.038
lung development GO:0030324 20 0.038
regulation of cardiac muscle tissue growth GO:0055021 4 0.038
negative regulation of phosphorylation GO:0042326 174 0.037
protein modification by small protein conjugation GO:0032446 342 0.037
negative regulation of catalytic activity GO:0043086 335 0.037
molting cycle GO:0042303 28 0.037
protein secretion GO:0009306 98 0.036
neuron development GO:0048666 113 0.036
Fly
negative regulation of protein metabolic process GO:0051248 391 0.036
morphogenesis of embryonic epithelium GO:0016331 4 0.035
leukocyte activation GO:0045321 164 0.035
embryonic camera type eye development GO:0031076 2 0.035
negative regulation of organelle organization GO:0010639 126 0.035
striated muscle tissue development GO:0014706 59 0.035
primary neural tube formation GO:0014020 3 0.034
head development GO:0060322 108 0.034
neuron projection morphogenesis GO:0048812 50 0.034
Fly
venous blood vessel development GO:0060841 2 0.034
positive regulation of growth GO:0045927 58 0.034
cardiac vascular smooth muscle cell differentiation GO:0060947 2 0.034
compound eye development GO:0048749 1 0.033
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.033
protein acylation GO:0043543 138 0.033
cellular macromolecule catabolic process GO:0044265 380 0.033
ribonucleoside monophosphate metabolic process GO:0009161 187 0.033
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.033
Fly
internal peptidyl lysine acetylation GO:0018393 97 0.033
embryonic camera type eye morphogenesis GO:0048596 2 0.032
peripheral nervous system development GO:0007422 2 0.032
Fly
negative regulation of cellular amine metabolic process GO:0033239 3 0.032
regulation of cellular response to stress GO:0080135 244 0.032
positive regulation of protein phosphorylation GO:0001934 313 0.032
response to other organism GO:0051707 261 0.032
Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.032
hair follicle development GO:0001942 11 0.031
regulation of mapk cascade GO:0043408 262 0.031
hair cycle process GO:0022405 12 0.031
embryonic epithelial tube formation GO:0001838 4 0.031
inflammatory response to antigenic stimulus GO:0002437 4 0.031
negative regulation of glial cell proliferation GO:0060253 2 0.031
response to organic cyclic compound GO:0014070 204 0.030
myoblast differentiation GO:0045445 21 0.030
chromatin assembly or disassembly GO:0006333 78 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
regulation of endodermal cell fate specification GO:0042663 1 0.030
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.030
regulation of synaptic plasticity GO:0048167 3 0.030
regulation of mitosis GO:0007088 63 0.029
regulation of glial cell proliferation GO:0060251 4 0.029
mesenchyme development GO:0060485 59 0.029
taxis GO:0042330 157 0.029
Fly
cytokine secretion GO:0050663 64 0.029
muscle cell fate commitment GO:0042693 4 0.029
nucleosome assembly GO:0006334 50 0.029
spermatid differentiation GO:0048515 4 0.029
microtubule cytoskeleton organization GO:0000226 176 0.029
ventral spinal cord development GO:0021517 1 0.029
regulation of protein transport GO:0051223 213 0.029
macromolecule methylation GO:0043414 97 0.029
myeloid leukocyte activation GO:0002274 34 0.028
artery morphogenesis GO:0048844 7 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
anterior posterior axis specification embryo GO:0008595 2 0.028
mesenchymal cell differentiation GO:0048762 52 0.028
forebrain generation of neurons GO:0021872 3 0.028
aorta development GO:0035904 2 0.028
regulation of neuron differentiation GO:0045664 70 0.028
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.027
regulation of protein localization GO:0032880 296 0.027
erbb signaling pathway GO:0038127 44 0.027
Fly
visual behavior GO:0007632 2 0.027
respiratory system development GO:0060541 22 0.027
protein localization to organelle GO:0033365 280 0.027
distal tubule development GO:0072017 4 0.026
urogenital system development GO:0001655 65 0.026
protein alkylation GO:0008213 74 0.026
histone methylation GO:0016571 60 0.026
cell part morphogenesis GO:0032990 137 0.026
Fly
determination of bilateral symmetry GO:0009855 15 0.026
organ growth GO:0035265 12 0.025
positive regulation of neural precursor cell proliferation GO:2000179 2 0.025
nerve development GO:0021675 4 0.025
demethylation GO:0070988 37 0.025
motor neuron axon guidance GO:0008045 2 0.025
positive regulation of neurogenesis GO:0050769 49 0.025
protein methylation GO:0006479 74 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
double strand break repair GO:0006302 101 0.024
morphogenesis of an epithelium GO:0002009 60 0.024
Fly
glycerolipid metabolic process GO:0046486 107 0.024
negative regulation of mapk cascade GO:0043409 56 0.024
tissue regeneration GO:0042246 3 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
cell proliferation in forebrain GO:0021846 1 0.024
sensory perception of pain GO:0019233 4 0.024
mesoderm development GO:0007498 14 0.023
regulation of chromatin organization GO:1902275 56 0.023
cell substrate adhesion GO:0031589 132 0.023
actin filament based process GO:0030029 224 0.023
jak stat cascade GO:0007259 46 0.023
regulation of canonical wnt signaling pathway GO:0060828 88 0.023
regulation of myotube differentiation GO:0010830 18 0.023
regulation of astrocyte differentiation GO:0048710 3 0.023
cell projection morphogenesis GO:0048858 129 0.023
Fly
sensory organ development GO:0007423 52 0.023
Fly
kidney epithelium development GO:0072073 25 0.023
rna splicing GO:0008380 131 0.022
Human
striated muscle cell differentiation GO:0051146 43 0.022
intracellular receptor signaling pathway GO:0030522 104 0.022
mesenchymal cell development GO:0014031 50 0.022
histone h3 k36 demethylation GO:0070544 5 0.022
negative regulation of chromosome organization GO:2001251 48 0.022
regulation of endothelial cell differentiation GO:0045601 4 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
mitotic cell cycle process GO:1903047 286 0.022
negative regulation of cell cycle GO:0045786 193 0.022
regulation of jak stat cascade GO:0046425 44 0.022
endocrine system development GO:0035270 26 0.022
nuclear division GO:0000280 128 0.022
nuclear transport GO:0051169 179 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
proteasomal protein catabolic process GO:0010498 176 0.022
startle response GO:0001964 3 0.021
embryonic hindlimb morphogenesis GO:0035116 2 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
lymphocyte activation GO:0046649 133 0.021
histone demethylation GO:0016577 15 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
response to steroid hormone GO:0048545 80 0.021
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.020
muscle tissue morphogenesis GO:0060415 19 0.020
regulation of histone modification GO:0031056 47 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
regulation of striated muscle tissue development GO:0016202 26 0.020
negative regulation of developmental process GO:0051093 247 0.020
cell adhesion GO:0007155 325 0.020
regulation of cellular component biogenesis GO:0044087 281 0.020
protein targeting GO:0006605 187 0.020
single organism reproductive process GO:0044702 98 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
cell type specific apoptotic process GO:0097285 125 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
regulation of membrane potential GO:0042391 95 0.019
cell matrix adhesion GO:0007160 85 0.019
cell proliferation involved in heart morphogenesis GO:0061323 1 0.019
embryonic eye morphogenesis GO:0048048 2 0.019
epidermis development GO:0008544 59 0.019
Fly
regulation of odontogenesis GO:0042481 4 0.019
response to alcohol GO:0097305 64 0.019
positive regulation of cell cycle phase transition GO:1901989 22 0.019
negative regulation of protein modification process GO:0031400 200 0.018
muscle tissue development GO:0060537 62 0.018
protein deubiquitination GO:0016579 79 0.018
heart valve formation GO:0003188 2 0.018
metencephalon development GO:0022037 2 0.018
single organism behavior GO:0044708 28 0.018
determination of left right asymmetry in lateral mesoderm GO:0003140 1 0.018
hindbrain development GO:0030902 3 0.018
regulation of developmental growth GO:0048638 30 0.018
cellular lipid metabolic process GO:0044255 303 0.018
regulation of chromosome organization GO:0033044 103 0.018
chromatin remodeling GO:0006338 55 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
protein demethylation GO:0006482 17 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
forebrain neuron differentiation GO:0021879 3 0.018
response to wounding GO:0009611 168 0.018
muscle structure development GO:0061061 98 0.018
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.018
positive regulation of organelle organization GO:0010638 195 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.017
tissue morphogenesis GO:0048729 96 0.017
Fly
negative regulation of glial cell differentiation GO:0045686 1 0.017
mitotic nuclear division GO:0007067 119 0.017
neural tube closure GO:0001843 3 0.017
ventricular cardiac muscle tissue development GO:0003229 14 0.017
purine ribonucleoside metabolic process GO:0046128 437 0.017
cell fate commitment GO:0045165 27 0.017
Fly
regulation of cardiac muscle tissue development GO:0055024 13 0.017
nuclear export GO:0051168 69 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
positive regulation of cell development GO:0010720 92 0.017
protein modification by small protein removal GO:0070646 92 0.017
endothelial cell differentiation GO:0045446 26 0.017
anterior posterior axis specification GO:0009948 2 0.017
skin development GO:0043588 76 0.017
Fly
interleukin 4 production GO:0032633 7 0.017
regulation of nucleocytoplasmic transport GO:0046822 98 0.017
regulation of mrna metabolic process GO:1903311 53 0.017
Human
regulation of organ morphogenesis GO:2000027 24 0.017
lipid metabolic process GO:0006629 381 0.017
behavioral response to ethanol GO:0048149 2 0.017
positive regulation of phosphorylation GO:0042327 394 0.016
spermatid development GO:0007286 4 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
glycerophospholipid metabolic process GO:0006650 84 0.016
positive regulation of gastrulation GO:2000543 2 0.016
sprouting angiogenesis GO:0002040 29 0.016
cardiac muscle cell proliferation GO:0060038 6 0.016
nitrogen compound transport GO:0071705 191 0.016
regulation of leukocyte differentiation GO:1902105 61 0.016
glomerular mesangial cell differentiation GO:0072008 2 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.016
renal system development GO:0072001 63 0.016
nucleotide catabolic process GO:0009166 408 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
regulation of mesodermal cell fate specification GO:0042661 2 0.016
regulation of response to dna damage stimulus GO:2001020 94 0.016
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
reproductive system development GO:0061458 56 0.016
embryonic hemopoiesis GO:0035162 4 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
regulation of cell development GO:0060284 161 0.015
regulation of chromatin modification GO:1903308 51 0.015

SPEN disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.019
sensory system disease DOID:0050155 203 0.018
eye and adnexa disease DOID:1492 150 0.018
nervous system disease DOID:863 431 0.018
eye disease DOID:5614 149 0.018
heart disease DOID:114 68 0.016
cardiovascular system disease DOID:1287 106 0.016