Homo sapiens

119 known processes

SPRY2

sprouty homolog 2 (Drosophila)

(Aliases: MGC23039,hSPRY2)

SPRY2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.829
Mouse Fly
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.816
Mouse Fly
negative regulation of cellular amine metabolic process GO:0033239 3 0.684
small gtpase mediated signal transduction GO:0007264 78 0.577
Mouse
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.571
Mouse
regulation of kinase activity GO:0043549 314 0.562
regulation of anatomical structure morphogenesis GO:0022603 286 0.514
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.505
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.489
Mouse
gtp catabolic process GO:0006184 237 0.486
Mouse
ribonucleotide catabolic process GO:0009261 405 0.447
Mouse
post embryonic development GO:0009791 2 0.440
regulation of cellular amine metabolic process GO:0033238 11 0.426
organophosphate catabolic process GO:0046434 430 0.408
Mouse
response to fibroblast growth factor GO:0071774 39 0.407
Mouse Fly
vesicle mediated transport GO:0016192 371 0.402
erk1 and erk2 cascade GO:0070371 104 0.385
regulation of cellular response to growth factor stimulus GO:0090287 76 0.385
Mouse Fly
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.377
Mouse Fly
purine ribonucleotide catabolic process GO:0009154 404 0.368
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.362
Mouse
negative regulation of map kinase activity GO:0043407 27 0.344
Mouse
negative regulation of cell death GO:0060548 345 0.342
regulation of cellular ketone metabolic process GO:0010565 50 0.342
synaptic vesicle endocytosis GO:0048488 2 0.338
ribonucleoside catabolic process GO:0042454 406 0.331
Mouse
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.324
Mouse
regulation of map kinase activity GO:0043405 108 0.314
Mouse
guanosine containing compound catabolic process GO:1901069 239 0.299
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.298
cellular response to endogenous stimulus GO:0071495 336 0.298
Mouse Fly
purine ribonucleoside catabolic process GO:0046130 398 0.280
Mouse
cellular amino acid metabolic process GO:0006520 116 0.276
negative regulation of peptidyl threonine phosphorylation GO:0010801 6 0.267
guanosine containing compound metabolic process GO:1901068 244 0.265
Mouse
peptidyl threonine phosphorylation GO:0018107 41 0.262
positive regulation of protein kinase b signaling GO:0051897 42 0.252
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.247
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.236
enzyme linked receptor protein signaling pathway GO:0007167 303 0.233
Mouse Fly
mesonephros development GO:0001823 17 0.233
purine nucleoside triphosphate metabolic process GO:0009144 412 0.231
Mouse
synaptic vesicle recycling GO:0036465 3 0.231
negative regulation of cell proliferation GO:0008285 228 0.230
Mouse
regulation of gtp catabolic process GO:0033124 180 0.221
Mouse
nucleotide catabolic process GO:0009166 408 0.194
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.186
Mouse Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.186
Mouse
circulatory system development GO:0072359 262 0.181
regulation of cellular amino acid metabolic process GO:0006521 6 0.179
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.178
Mouse
glycosyl compound catabolic process GO:1901658 413 0.175
Mouse
positive regulation of cell death GO:0010942 263 0.172
urogenital system development GO:0001655 65 0.170
gtp metabolic process GO:0046039 239 0.169
Mouse
negative regulation of mapk cascade GO:0043409 56 0.164
Mouse
immune system development GO:0002520 195 0.164
negative regulation of phosphorylation GO:0042326 174 0.159
signal transduction by phosphorylation GO:0023014 297 0.148
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.142
Mouse Fly
amine metabolic process GO:0009308 44 0.141
mapk cascade GO:0000165 288 0.141
ameboidal type cell migration GO:0001667 135 0.140
regulation of ras protein signal transduction GO:0046578 155 0.138
Mouse
purine containing compound catabolic process GO:0072523 411 0.135
Mouse
positive regulation of developmental process GO:0051094 314 0.135
nucleoside triphosphate metabolic process GO:0009141 422 0.134
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.133
ras protein signal transduction GO:0007265 73 0.131
Mouse
positive regulation of p38mapk cascade GO:1900745 8 0.129
nucleoside catabolic process GO:0009164 408 0.125
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.125
negative regulation of phosphate metabolic process GO:0045936 267 0.121
positive regulation of mapk cascade GO:0043410 190 0.120
actin filament organization GO:0007015 128 0.118
protein catabolic process GO:0030163 325 0.114
regulation of cellular component biogenesis GO:0044087 281 0.108
organ morphogenesis GO:0009887 147 0.107
Mouse Fly
cell cell signaling GO:0007267 155 0.107
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.105
anatomical structure formation involved in morphogenesis GO:0048646 284 0.105
regulation of nucleoside metabolic process GO:0009118 209 0.104
Mouse
determination of adult lifespan GO:0008340 2 0.103
regulation of protein kinase activity GO:0045859 289 0.101
peptidyl threonine modification GO:0018210 45 0.100
ribonucleoside triphosphate catabolic process GO:0009203 391 0.099
Mouse
negative regulation of kinase activity GO:0033673 106 0.099
Mouse
positive regulation of kinase activity GO:0033674 204 0.098
organ formation GO:0048645 3 0.095
regulation of locomotion GO:0040012 329 0.094
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.091
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.089
mesonephric epithelium development GO:0072163 14 0.089
regulation of transferase activity GO:0051338 355 0.089
regulation of cell differentiation GO:0045595 393 0.088
Fly
response to growth factor GO:0070848 205 0.087
Mouse Fly
cellular macromolecule catabolic process GO:0044265 380 0.086
hindbrain development GO:0030902 3 0.084
actin cytoskeleton organization GO:0030036 207 0.082
cdc42 protein signal transduction GO:0032488 4 0.080
negative regulation of programmed cell death GO:0043069 321 0.080
single organism cell adhesion GO:0098602 179 0.078
cell activation GO:0001775 213 0.077
branch elongation of an epithelium GO:0060602 3 0.075
Mouse
regulation of lymphocyte activation GO:0051249 103 0.075
multicellular organismal aging GO:0010259 3 0.075
negative regulation of apoptotic process GO:0043066 316 0.074
regulation of organ formation GO:0003156 4 0.074
immune response GO:0006955 307 0.070
eye photoreceptor cell differentiation GO:0001754 2 0.069
Fly
positive regulation of gtp catabolic process GO:0033126 166 0.067
regulation of protein serine threonine kinase activity GO:0071900 179 0.067
nucleoside phosphate catabolic process GO:1901292 412 0.067
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.066
regulation of nucleotide catabolic process GO:0030811 205 0.066
Mouse
negative regulation of transferase activity GO:0051348 124 0.066
Mouse
regulation of mapk cascade GO:0043408 262 0.065
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.064
Mouse
actin filament based process GO:0030029 224 0.063
positive regulation of jnk cascade GO:0046330 52 0.063
response to uv GO:0009411 73 0.063
neural crest cell development GO:0014032 3 0.062
negative regulation of catalytic activity GO:0043086 335 0.061
Mouse
positive regulation of locomotion GO:0040017 186 0.061
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.061
negative regulation of protein modification process GO:0031400 200 0.061
keratinization GO:0031424 2 0.061
rho protein signal transduction GO:0007266 26 0.060
single organismal cell cell adhesion GO:0016337 148 0.060
negative regulation of hydrolase activity GO:0051346 182 0.057
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.057
Mouse
epithelium development GO:0060429 227 0.057
Mouse Fly
leukocyte activation GO:0045321 164 0.055
biological adhesion GO:0022610 331 0.055
regulation of erk1 and erk2 cascade GO:0070372 99 0.054
purine nucleoside triphosphate catabolic process GO:0009146 392 0.053
Mouse
mitotic cell cycle process GO:1903047 286 0.053
Mouse
glial cell development GO:0021782 7 0.053
Fly
regulation of secretion GO:0051046 194 0.052
positive regulation of cellular component organization GO:0051130 376 0.051
organic hydroxy compound metabolic process GO:1901615 147 0.051
muscle tissue development GO:0060537 62 0.050
positive regulation of cell proliferation GO:0008284 301 0.050
purine nucleotide catabolic process GO:0006195 405 0.050
Mouse
branching morphogenesis of an epithelial tube GO:0048754 19 0.050
Mouse Fly
epithelial cell migration GO:0010631 119 0.049
muscle structure development GO:0061061 98 0.049
Fly
innate immune response GO:0045087 178 0.049
cellular response to abiotic stimulus GO:0071214 117 0.048
negative regulation of protein kinase activity GO:0006469 98 0.048
Mouse
hyperosmotic response GO:0006972 4 0.048
sequestering of extracellular ligand from receptor GO:0035581 3 0.047
pattern specification process GO:0007389 43 0.046
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.046
negative regulation of protein phosphorylation GO:0001933 140 0.046
cellular protein catabolic process GO:0044257 261 0.046
establishment of organelle localization GO:0051656 59 0.045
Mouse
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.045
Mouse Fly
neurotrophin trk receptor signaling pathway GO:0048011 4 0.044
Mouse
epithelium migration GO:0090132 119 0.044
cardiovascular system development GO:0072358 262 0.044
positive regulation of nucleotide catabolic process GO:0030813 185 0.044
response to drug GO:0042493 81 0.043
hormone metabolic process GO:0042445 61 0.043
regulation of cytoskeleton organization GO:0051493 177 0.043
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.042
natural killer cell differentiation GO:0001779 2 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.042
negative regulation of bmp signaling pathway GO:0030514 17 0.042
intrinsic apoptotic signaling pathway GO:0097193 127 0.042
mitotic cell cycle GO:0000278 326 0.041
Mouse
organ induction GO:0001759 4 0.041
regulation of proteolysis GO:0030162 293 0.041
secretion GO:0046903 254 0.041
positive regulation of apoptotic process GO:0043065 246 0.041
positive regulation of aldosterone metabolic process GO:0032346 2 0.040
metanephros development GO:0001656 16 0.040
photoreceptor cell differentiation GO:0046530 2 0.040
Fly
positive regulation of peptidase activity GO:0010952 88 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.040
cellular amine metabolic process GO:0044106 41 0.040
positive regulation of cell size GO:0045793 3 0.040
morphogenesis of embryonic epithelium GO:0016331 4 0.039
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.039
ubiquitin dependent protein catabolic process GO:0006511 206 0.039
negative regulation of camp mediated signaling GO:0043951 4 0.039
regulation of nucleotide metabolic process GO:0006140 269 0.039
Mouse
cellular ketone metabolic process GO:0042180 80 0.038
cell division GO:0051301 168 0.038
positive regulation of programmed cell death GO:0043068 249 0.038
positive regulation of cellular catabolic process GO:0031331 284 0.038
positive regulation of secretion by cell GO:1903532 108 0.037
positive regulation of rac gtpase activity GO:0032855 31 0.037
negative regulation of organelle organization GO:0010639 126 0.037
regulation of gtpase activity GO:0043087 180 0.037
Mouse
secretion by cell GO:0032940 226 0.037
nervous system development GO:0007399 293 0.037
Fly
positive regulation of synaptic transmission GO:0050806 4 0.037
regulation of cell migration GO:0030334 289 0.037
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.036
kidney development GO:0001822 53 0.036
peptidyl serine modification GO:0018209 106 0.036
response to oxygen containing compound GO:1901700 369 0.036
regulation of peptidase activity GO:0052547 180 0.036
stress fiber assembly GO:0043149 40 0.036
hair follicle morphogenesis GO:0031069 2 0.035
cell adhesion GO:0007155 325 0.034
negative regulation of cellular component organization GO:0051129 235 0.034
associative learning GO:0008306 1 0.034
regulation of jnk cascade GO:0046328 73 0.034
negative regulation of small gtpase mediated signal transduction GO:0051058 12 0.034
Mouse
regulation of small gtpase mediated signal transduction GO:0051056 156 0.034
Mouse
mesonephric tubule development GO:0072164 14 0.034
membrane organization GO:0061024 292 0.034
positive regulation of protein complex assembly GO:0031334 86 0.033
regulation of cell projection organization GO:0031344 107 0.033
behavior GO:0007610 112 0.032
sex determination GO:0007530 3 0.032
negative regulation of locomotion GO:0040013 118 0.031
cell projection organization GO:0030030 252 0.031
central nervous system development GO:0007417 123 0.031
muscle fiber development GO:0048747 16 0.031
Fly
positive regulation of cellular component biogenesis GO:0044089 158 0.031
protein kinase b signaling GO:0043491 69 0.031
regulation of epithelial cell proliferation GO:0050678 113 0.031
regeneration GO:0031099 4 0.031
cellular response to uv GO:0034644 32 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
Mouse
melanin metabolic process GO:0006582 1 0.030
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.030
spermatid development GO:0007286 4 0.030
actin filament bundle assembly GO:0051017 54 0.030
dephosphorylation GO:0016311 209 0.030
engulfment of apoptotic cell GO:0043652 2 0.029
negative regulation of cell migration GO:0030336 102 0.029
hematopoietic or lymphoid organ development GO:0048534 186 0.029
regulation of cell motility GO:2000145 299 0.029
organelle localization GO:0051640 84 0.029
Mouse
positive regulation of phosphorylation GO:0042327 394 0.029
positive regulation of catabolic process GO:0009896 310 0.029
positive regulation of nucleotide metabolic process GO:0045981 230 0.029
reproductive process GO:0022414 106 0.029
response to nitrogen compound GO:1901698 184 0.029
membrane tubulation GO:0097320 12 0.029
regulation of natural killer cell differentiation GO:0032823 2 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.028
regulation of stress fiber assembly GO:0051492 32 0.028
oxidation reduction process GO:0055114 396 0.028
cellular response to glucocorticoid stimulus GO:0071385 4 0.028
positive regulation of proteolysis GO:0045862 142 0.028
positive regulation of necrotic cell death GO:0010940 4 0.028
positive regulation of protein phosphorylation GO:0001934 313 0.028
immune effector process GO:0002252 159 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.028
kidney epithelium development GO:0072073 25 0.028
multicellular organismal response to stress GO:0033555 1 0.027
protein maturation GO:0051604 233 0.027
locomotory behavior GO:0007626 1 0.027
positive regulation of endocytosis GO:0045807 42 0.027
positive regulation of cell development GO:0010720 92 0.027
prostate gland stromal morphogenesis GO:0060741 1 0.027
response to mechanical stimulus GO:0009612 51 0.027
positive regulation of gtpase activity GO:0043547 166 0.027
cell fate determination GO:0001709 3 0.027
regulation of cell activation GO:0050865 125 0.027
regulation of stress activated mapk cascade GO:0032872 84 0.026
regulation of extracellular vesicular exosome assembly GO:1903551 4 0.026
compound eye development GO:0048749 1 0.026
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
Mouse
ureteric bud development GO:0001657 13 0.026
molting cycle GO:0042303 28 0.026
lipid metabolic process GO:0006629 381 0.025
positive regulation of cell projection organization GO:0031346 64 0.025
bmp signaling pathway GO:0030509 49 0.025
protein ubiquitination GO:0016567 314 0.025
regulation of protein catabolic process GO:0042176 155 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
epithelial tube morphogenesis GO:0060562 38 0.024
Mouse Fly
lymphocyte activation GO:0046649 133 0.024
cell chemotaxis GO:0060326 112 0.024
spermatid differentiation GO:0048515 4 0.024
regulation of bmp signaling pathway GO:0030510 27 0.024
response to organic cyclic compound GO:0014070 204 0.024
gliogenesis GO:0042063 21 0.024
Fly
arf protein signal transduction GO:0032011 0 0.024
negative regulation of interleukin 6 biosynthetic process GO:0045409 3 0.024
negative regulation of cytokine production GO:0001818 82 0.024
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.023
positive regulation of protein catabolic process GO:0045732 75 0.023
stress activated mapk cascade GO:0051403 93 0.023
myeloid cell differentiation GO:0030099 117 0.023
regulation of cell cycle process GO:0010564 266 0.023
regulation of growth GO:0040008 165 0.023
response to organonitrogen compound GO:0010243 156 0.023
ureter development GO:0072189 3 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
hormone biosynthetic process GO:0042446 22 0.022
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.022
regulation of endopeptidase activity GO:0052548 170 0.022
positive regulation of ras gtpase activity GO:0032320 117 0.022
positive regulation of cell adhesion GO:0045785 84 0.022
protein oligomerization GO:0051259 173 0.022
notch signaling pathway GO:0007219 31 0.022
nitrogen compound transport GO:0071705 191 0.022
maintenance of location GO:0051235 112 0.022
regulation of epithelial cell migration GO:0010632 93 0.022
meiosis i GO:0007127 4 0.022
cellular response to nitrogen compound GO:1901699 144 0.021
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
cell morphogenesis GO:0000902 296 0.021
regulation of arf protein signal transduction GO:0032012 1 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
Mouse
regulation of neuronal synaptic plasticity GO:0048168 1 0.021
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.021
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.021
forelimb morphogenesis GO:0035136 4 0.021
regulation of cellular component movement GO:0051270 334 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.021
activation of protein kinase activity GO:0032147 90 0.021
carbohydrate metabolic process GO:0005975 207 0.020
positive regulation of behavior GO:0048520 60 0.020
response to transforming growth factor beta GO:0071559 94 0.020
mononuclear cell proliferation GO:0032943 71 0.020
regulation of secretion by cell GO:1903530 177 0.020
cytokinesis GO:0000910 96 0.020
positive regulation of immune system process GO:0002684 283 0.020
peptidyl tyrosine dephosphorylation GO:0035335 36 0.020
regulation of cell development GO:0060284 161 0.020
Fly
cation transport GO:0006812 331 0.020
atp metabolic process GO:0046034 176 0.020
microtubule based process GO:0007017 210 0.020
Mouse
cell projection morphogenesis GO:0048858 129 0.020
response to abiotic stimulus GO:0009628 336 0.020
epithelial cell differentiation GO:0030855 141 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.020
positive regulation of secretion GO:0051047 116 0.019
ribonucleoside monophosphate metabolic process GO:0009161 187 0.019
skeletal muscle tissue development GO:0007519 24 0.019
short term memory GO:0007614 1 0.019
developmental process involved in reproduction GO:0003006 66 0.019
regulation of actin filament based process GO:0032970 141 0.019
renal system development GO:0072001 63 0.019
regulation of cytokine production GO:0001817 232 0.019
cardiac right ventricle morphogenesis GO:0003215 3 0.019
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.019
heart development GO:0007507 95 0.019
single organism reproductive process GO:0044702 98 0.019
negative regulation of immune system process GO:0002683 136 0.019
anatomical structure homeostasis GO:0060249 100 0.019
regulation of protein complex assembly GO:0043254 147 0.019
response to light stimulus GO:0009416 87 0.019
positive regulation of map kinase activity GO:0043406 80 0.019
striated muscle cell differentiation GO:0051146 43 0.018
Fly
peptidyl serine phosphorylation GO:0018105 101 0.018
cell projection assembly GO:0030031 126 0.018
negative regulation of developmental process GO:0051093 247 0.018
negative regulation of regulated secretory pathway GO:1903306 1 0.018
cytoplasmic transport GO:0016482 379 0.018
cellular component morphogenesis GO:0032989 314 0.018
positive regulation of cytokine production GO:0001819 167 0.018
endocytosis GO:0006897 159 0.018
protein secretion GO:0009306 98 0.018
limbic system development GO:0021761 3 0.018
regionalization GO:0003002 29 0.018
cytokine production GO:0001816 247 0.018
positive regulation of organelle organization GO:0010638 195 0.018
protein dephosphorylation GO:0006470 81 0.018
regulation of microtubule cytoskeleton organization GO:0070507 61 0.017
response to biotic stimulus GO:0009607 276 0.017
cellular protein complex assembly GO:0043623 188 0.017
glial cell differentiation GO:0010001 11 0.017
Fly
positive regulation of axon extension GO:0045773 4 0.017
canonical wnt signaling pathway GO:0060070 116 0.017
heart contraction GO:0060047 62 0.017
negative regulation of apoptotic signaling pathway GO:2001234 97 0.017
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.017
negative regulation of endopeptidase activity GO:0010951 84 0.017
detection of stimulus GO:0051606 85 0.017
positive regulation of leukocyte activation GO:0002696 80 0.017
regulation of dna metabolic process GO:0051052 153 0.017
response to acid chemical GO:0001101 66 0.017
dna conformation change GO:0071103 113 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
cellular response to lipid GO:0071396 127 0.017
plasma membrane organization GO:0007009 115 0.017
tube development GO:0035295 125 0.017
Mouse Fly
cell cycle phase transition GO:0044770 173 0.017
negative regulation of growth GO:0045926 97 0.017
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 7 0.016
Mouse Fly
rap protein signal transduction GO:0032486 7 0.016
formation of primary germ layer GO:0001704 42 0.016
skeletal muscle organ development GO:0060538 26 0.016
regulation of system process GO:0044057 101 0.016
axis elongation GO:0003401 4 0.016
Mouse
response to radiation GO:0009314 151 0.016
regulation of peptidyl serine phosphorylation GO:0033135 50 0.016
regulation of myeloid cell differentiation GO:0045637 81 0.016
negative regulation of cytoskeleton organization GO:0051494 45 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
cerebellum development GO:0021549 2 0.016
regulation of blood coagulation GO:0030193 42 0.016
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.016
regulation of protein processing GO:0070613 150 0.016
cellular response to toxic substance GO:0097237 4 0.016
negative regulation of monocyte differentiation GO:0045656 3 0.016
striated muscle tissue development GO:0014706 59 0.015
autophagic cell death GO:0048102 3 0.015
actin filament bundle organization GO:0061572 54 0.015
semaphorin plexin signaling pathway GO:0071526 4 0.015
regulation of anatomical structure size GO:0090066 101 0.015
hemopoiesis GO:0030097 180 0.015
neuromuscular junction development GO:0007528 3 0.015
tor signaling GO:0031929 39 0.015
mucosal immune response GO:0002385 21 0.015
cell part morphogenesis GO:0032990 137 0.015
actomyosin structure organization GO:0031032 59 0.015
regulation of glial cell differentiation GO:0045685 3 0.015
regulation of lipid metabolic process GO:0019216 96 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
cellular response to hormone stimulus GO:0032870 125 0.015
golgi vesicle transport GO:0048193 80 0.015
negative regulation of wnt signaling pathway GO:0030178 69 0.015
tissue homeostasis GO:0001894 63 0.015
regulation of actin filament bundle assembly GO:0032231 36 0.015
epithelial cell proliferation GO:0050673 128 0.015
negative regulation of cell motility GO:2000146 104 0.015
neuron fate commitment GO:0048663 2 0.015
vesicle organization GO:0016050 62 0.014
lung morphogenesis GO:0060425 6 0.014
Mouse
defense response GO:0006952 315 0.014
reproductive structure development GO:0048608 55 0.014
endosomal transport GO:0016197 129 0.014
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.014
muscle cell development GO:0055001 29 0.014
Fly
regulation of cellular protein catabolic process GO:1903362 96 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
axon regeneration GO:0031103 1 0.014
neurogenesis GO:0022008 169 0.014
Fly
metal ion transport GO:0030001 272 0.014
regulation of dendritic cell apoptotic process GO:2000668 4 0.014
negative regulation of hydrogen peroxide mediated programmed cell death GO:1901299 3 0.014
regulation of hormone metabolic process GO:0032350 14 0.014
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.014
positive regulation of hormone biosynthetic process GO:0046886 4 0.014
regulation of microtubule based process GO:0032886 74 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
Mouse
female gamete generation GO:0007292 2 0.014
lipid biosynthetic process GO:0008610 177 0.014
metanephric s shaped body morphogenesis GO:0072284 4 0.014
positive regulation of myeloid cell differentiation GO:0045639 39 0.014
prostate gland development GO:0030850 3 0.014
chromatin organization GO:0006325 351 0.014
positive regulation of leukocyte differentiation GO:1902107 37 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
positive regulation of cellular component movement GO:0051272 181 0.013
cellular response to histamine GO:0071420 3 0.013
endodermal cell fate commitment GO:0001711 4 0.013
growth GO:0040007 202 0.013
Mouse
prostate gland morphogenesis GO:0060512 1 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
keratinocyte differentiation GO:0030216 36 0.013
leukocyte proliferation GO:0070661 74 0.013

SPRY2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.214
musculoskeletal system disease DOID:17 223 0.125
neuromuscular disease DOID:440 38 0.108
nervous system disease DOID:863 431 0.108
neuropathy DOID:870 52 0.108
cancer DOID:162 167 0.059
organ system cancer DOID:0050686 164 0.059
kidney disease DOID:557 36 0.037
urinary system disease DOID:18 40 0.037
bone disease DOID:0080001 88 0.034
connective tissue disease DOID:65 109 0.034
disease of metabolism DOID:0014667 295 0.031
immune system disease DOID:2914 155 0.031
muscular disease DOID:0080000 114 0.024
muscle tissue disease DOID:66 113 0.024
cardiovascular system disease DOID:1287 106 0.021
myopathy DOID:423 104 0.019
gastrointestinal system cancer DOID:3119 52 0.017
gastrointestinal system disease DOID:77 36 0.017
phaeochromocytoma DOID:0050771 8 0.017
cell type benign neoplasm DOID:0060084 10 0.017
benign neoplasm DOID:0060072 18 0.017
central nervous system disease DOID:331 186 0.016
heart disease DOID:114 68 0.015
acquired metabolic disease DOID:0060158 58 0.015