Homo sapiens

66 known processes

SREBF1

sterol regulatory element binding transcription factor 1

(Aliases: SREBP1,SREBP-1c,bHLHd1)

SREBF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal aging GO:0010259 3 0.255
Worm
post embryonic development GO:0009791 2 0.228
Worm
lipid metabolic process GO:0006629 381 0.204
Mouse Rat Worm
regulation of cell differentiation GO:0045595 393 0.173
lipid localization GO:0010876 106 0.164
Human Worm
long chain fatty acid metabolic process GO:0001676 30 0.136
positive regulation of developmental process GO:0051094 314 0.132
Worm
response to other organism GO:0051707 261 0.089
regulation of apoptotic signaling pathway GO:2001233 175 0.086
histone acetylation GO:0016573 93 0.086
lipid biosynthetic process GO:0008610 177 0.086
Mouse
internal protein amino acid acetylation GO:0006475 101 0.082
apoptotic signaling pathway GO:0097190 268 0.081
cellular protein complex assembly GO:0043623 188 0.081
cellular lipid metabolic process GO:0044255 303 0.080
Mouse
negative regulation of calcium ion import GO:0090281 1 0.078
organic acid biosynthetic process GO:0016053 97 0.074
protein catabolic process GO:0030163 325 0.073
monocarboxylic acid metabolic process GO:0032787 185 0.073
Mouse
protein deubiquitination GO:0016579 79 0.072
determination of adult lifespan GO:0008340 2 0.072
Worm
organic hydroxy compound transport GO:0015850 63 0.071
Human
transmembrane transport GO:0055085 399 0.070
sterol transport GO:0015918 39 0.069
Human
regulation of cellular component biogenesis GO:0044087 281 0.068
regulation of protein complex assembly GO:0043254 147 0.067
chemical homeostasis GO:0048878 306 0.066
regulation of growth GO:0040008 165 0.064
Worm
nervous system development GO:0007399 293 0.063
morphogenesis of embryonic epithelium GO:0016331 4 0.063
regulation of cellular ketone metabolic process GO:0010565 50 0.062
Mouse
fatty acid metabolic process GO:0006631 115 0.061
Mouse
small molecule biosynthetic process GO:0044283 157 0.061
Mouse
locomotory behavior GO:0007626 1 0.060
mating GO:0007618 1 0.059
protein acylation GO:0043543 138 0.057
negative regulation of phosphate metabolic process GO:0045936 267 0.057
posttranscriptional regulation of gene expression GO:0010608 213 0.056
positive regulation of protein complex assembly GO:0031334 86 0.056
amine metabolic process GO:0009308 44 0.056
regulation of cholesterol homeostasis GO:2000188 2 0.055
regulation of immune response GO:0050776 201 0.054
cellular ketone metabolic process GO:0042180 80 0.052
Mouse
oogenesis GO:0048477 2 0.052
protein modification by small protein conjugation GO:0032446 342 0.051
positive regulation of organelle organization GO:0010638 195 0.051
Mouse
histone modification GO:0016570 251 0.050
Mouse
organic anion transport GO:0015711 103 0.049
response to abiotic stimulus GO:0009628 336 0.049
Worm
mitotic cell cycle GO:0000278 326 0.049
organonitrogen compound biosynthetic process GO:1901566 200 0.049
cellular amine metabolic process GO:0044106 41 0.048
protein polymerization GO:0051258 71 0.048
response to external biotic stimulus GO:0043207 261 0.048
regulation of interleukin 2 secretion GO:1900040 2 0.048
internal peptidyl lysine acetylation GO:0018393 97 0.048
monocarboxylic acid biosynthetic process GO:0072330 67 0.046
regulation of anatomical structure size GO:0090066 101 0.046
steroid metabolic process GO:0008202 94 0.046
Mouse Rat
sterol homeostasis GO:0055092 28 0.045
actin polymerization or depolymerization GO:0008154 56 0.045
fatty acid biosynthetic process GO:0006633 46 0.045
response to hormone GO:0009725 175 0.045
Mouse Rat
regulation of cellular component size GO:0032535 82 0.045
negative regulation of cell differentiation GO:0045596 171 0.044
regulation of response to external stimulus GO:0032101 222 0.044
anion transport GO:0006820 161 0.043
regulation of cellular amine metabolic process GO:0033238 11 0.043
embryonic epithelial tube formation GO:0001838 4 0.043
negative regulation of cell cycle GO:0045786 193 0.043
negative regulation of transport GO:0051051 176 0.042
Human Mouse
peptidyl lysine modification GO:0018205 144 0.042
viral life cycle GO:0019058 132 0.041
protein acetylation GO:0006473 116 0.041
cellular macromolecule catabolic process GO:0044265 380 0.041
vesicle mediated transport GO:0016192 371 0.041
metal ion transport GO:0030001 272 0.041
positive regulation of cellular component organization GO:0051130 376 0.041
Mouse
interspecies interaction between organisms GO:0044419 156 0.041
protein processing GO:0016485 226 0.041
regulation of defense response GO:0031347 154 0.040
response to bacterium GO:0009617 144 0.040
regulation of cell cycle process GO:0010564 266 0.040
defense response to other organism GO:0098542 129 0.040
regulation of intracellular transport of viral material GO:1901252 2 0.039
positive regulation of cytokine production GO:0001819 167 0.039
negative regulation of phosphorylation GO:0042326 174 0.038
female gamete generation GO:0007292 2 0.038
mapk cascade GO:0000165 288 0.037
regulation of hormone levels GO:0010817 125 0.037
Mouse
cellular macromolecular complex assembly GO:0034622 324 0.036
endomembrane system organization GO:0010256 196 0.036
cholesterol homeostasis GO:0042632 28 0.036
positive regulation of phosphorylation GO:0042327 394 0.036
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.035
response to oxygen levels GO:0070482 100 0.035
Worm
cellular amino acid metabolic process GO:0006520 116 0.035
negative regulation of protein modification process GO:0031400 200 0.035
peptidyl lysine acetylation GO:0018394 101 0.034
long chain fatty acid biosynthetic process GO:0042759 4 0.034
response to oxygen containing compound GO:1901700 369 0.033
Mouse Rat
actin filament organization GO:0007015 128 0.033
lipid transport GO:0006869 90 0.033
Human
adult locomotory behavior GO:0008344 1 0.032
regulation of nucleoside metabolic process GO:0009118 209 0.032
viral gene expression GO:0019080 35 0.032
regulation of neural precursor cell proliferation GO:2000177 4 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.031
regulation of protein polymerization GO:0032271 63 0.031
membrane organization GO:0061024 292 0.031
carbohydrate metabolic process GO:0005975 207 0.031
divalent metal ion transport GO:0070838 152 0.030
viral transcription GO:0019083 35 0.030
cytoplasmic transport GO:0016482 379 0.030
single organism membrane organization GO:0044802 268 0.030
cellular response to nutrient levels GO:0031669 69 0.030
Mouse Rat
negative regulation of protein metabolic process GO:0051248 391 0.030
regulation of cytokine production GO:0001817 232 0.030
positive regulation of cell cycle GO:0045787 140 0.030
positive regulation of lipid storage GO:0010884 10 0.030
Human Worm
positive regulation of cellular component biogenesis GO:0044089 158 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
neural tube formation GO:0001841 3 0.028
cell cycle arrest GO:0007050 71 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
regulation of protein localization GO:0032880 296 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.028
regulation of ion transmembrane transport GO:0034765 132 0.028
adaptive immune response GO:0002250 49 0.027
cholesterol transport GO:0030301 39 0.027
Human
neuroblast proliferation GO:0007405 4 0.027
negative regulation of developmental process GO:0051093 247 0.027
modification dependent protein catabolic process GO:0019941 209 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.027
single organism carbohydrate metabolic process GO:0044723 193 0.027
carbohydrate derivative biosynthetic process GO:1901137 207 0.027
regulation of cell development GO:0060284 161 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
negative regulation of catabolic process GO:0009895 104 0.027
photoreceptor cell differentiation GO:0046530 2 0.027
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.027
ion transmembrane transport GO:0034220 338 0.026
microtubule based process GO:0007017 210 0.026
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.026
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.025
primary neural tube formation GO:0014020 3 0.025
cell morphogenesis GO:0000902 296 0.025
regulation of ion transport GO:0043269 189 0.025
response to biotic stimulus GO:0009607 276 0.025
mitotic cell cycle process GO:1903047 286 0.025
innate immune response GO:0045087 178 0.025
negative regulation of immune system process GO:0002683 136 0.025
carbon catabolite activation of transcription GO:0045991 3 0.025
organic hydroxy compound metabolic process GO:1901615 147 0.025
Mouse Rat
response to low density lipoprotein particle GO:0055098 4 0.024
Human
regulation of response to biotic stimulus GO:0002831 55 0.024
cardiovascular system development GO:0072358 262 0.024
protein oligomerization GO:0051259 173 0.024
peripheral nervous system development GO:0007422 2 0.024
entry into host GO:0044409 25 0.024
lung alveolus development GO:0048286 4 0.024
maintenance of location GO:0051235 112 0.024
Human Worm
actin filament based process GO:0030029 224 0.024
interleukin 2 secretion GO:0070970 3 0.024
regulation of cell growth GO:0001558 135 0.024
embryo development GO:0009790 123 0.024
Worm
negative regulation of wnt signaling pathway GO:0030178 69 0.024
blastoderm segmentation GO:0007350 2 0.024
myeloid cell differentiation GO:0030099 117 0.023
regulation of protein deubiquitination GO:0090085 4 0.023
steroid biosynthetic process GO:0006694 46 0.023
Mouse
positive regulation of immune system process GO:0002684 283 0.023
secretion by cell GO:0032940 226 0.023
Mouse
response to cytokine GO:0034097 232 0.023
regulation of metal ion transport GO:0010959 120 0.023
hematopoietic or lymphoid organ development GO:0048534 186 0.022
response to decreased oxygen levels GO:0036293 96 0.022
Worm
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.022
positive regulation of locomotion GO:0040017 186 0.022
regulation of proteolysis GO:0030162 293 0.022
defense response GO:0006952 315 0.022
protein maturation GO:0051604 233 0.022
cholesterol metabolic process GO:0008203 28 0.022
Mouse Rat
segmentation GO:0035282 4 0.022
regulation of secretion by cell GO:1903530 177 0.022
Mouse
regulation of homeostatic process GO:0032844 121 0.022
neurogenesis GO:0022008 169 0.022
cytokine production GO:0001816 247 0.022
response to extracellular stimulus GO:0009991 85 0.022
Mouse Rat
growth GO:0040007 202 0.021
Worm
regulation of cell cycle GO:0051726 393 0.021
negative regulation of kinase activity GO:0033673 106 0.021
regulation of actin filament based process GO:0032970 141 0.021
lipid homeostasis GO:0055088 39 0.021
monosaccharide metabolic process GO:0005996 74 0.021
immune response GO:0006955 307 0.021
positive regulation of actin filament polymerization GO:0030838 38 0.021
viral process GO:0016032 146 0.021
memory GO:0007613 3 0.021
regulation of protein kinase activity GO:0045859 289 0.021
endocytosis GO:0006897 159 0.021
positive regulation of cell death GO:0010942 263 0.020
cellular response to cytokine stimulus GO:0071345 181 0.020
response to organonitrogen compound GO:0010243 156 0.020
Mouse Rat
protein secretion GO:0009306 98 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
regulation of immune effector process GO:0002697 91 0.020
oocyte development GO:0048599 1 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
negative regulation of proteolysis GO:0045861 132 0.020
response to nutrient levels GO:0031667 81 0.020
Mouse Rat
defense response to virus GO:0051607 71 0.020
actin cytoskeleton organization GO:0030036 207 0.020
histone h4 acetylation GO:0043967 47 0.020
cellular response to extracellular stimulus GO:0031668 72 0.020
Mouse Rat
circadian behavior GO:0048512 2 0.019
negative regulation of transferase activity GO:0051348 124 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
regulation of transferase activity GO:0051338 355 0.019
neuromuscular junction development GO:0007528 3 0.019
lipid catabolic process GO:0016042 84 0.019
regulation of protein maturation GO:1903317 150 0.019
glycerolipid metabolic process GO:0046486 107 0.019
Mouse
i kappab kinase nf kappab signaling GO:0007249 166 0.019
cellular carbohydrate metabolic process GO:0044262 84 0.019
negative regulation of growth GO:0045926 97 0.019
hindbrain development GO:0030902 3 0.019
regulation of mapk cascade GO:0043408 262 0.019
regulation of neuroblast proliferation GO:1902692 3 0.019
negative regulation of cell development GO:0010721 48 0.019
regulation of locomotion GO:0040012 329 0.019
positive regulation of viral entry into host cell GO:0046598 3 0.019
regulation of actin filament length GO:0030832 56 0.018
negative regulation of multi organism process GO:0043901 92 0.018
cell development GO:0048468 328 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
multi organism metabolic process GO:0044033 41 0.018
neuron projection development GO:0031175 106 0.018
response to virus GO:0009615 126 0.018
cellular response to external stimulus GO:0071496 111 0.018
Mouse Rat
gonad development GO:0008406 34 0.018
Worm
regulation of cellular response to stress GO:0080135 244 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
negative regulation of cell proliferation GO:0008285 228 0.018
regulation of kinase activity GO:0043549 314 0.018
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.018
chromatin organization GO:0006325 351 0.018
Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
regulation of cellular protein catabolic process GO:1903362 96 0.018
regulation of gene expression epigenetic GO:0040029 73 0.018
response to glucagon GO:0033762 1 0.018
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
stem cell development GO:0048864 69 0.017
syncytium formation by plasma membrane fusion GO:0000768 2 0.017
negative regulation of protein deubiquitination GO:0090086 3 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
inner ear morphogenesis GO:0042472 4 0.017
regulation of actin cytoskeleton organization GO:0032956 116 0.017
ribose phosphate biosynthetic process GO:0046390 82 0.017
g protein coupled receptor signaling pathway GO:0007186 207 0.017
response to hypoxia GO:0001666 96 0.017
regulation of innate immune response GO:0045088 97 0.017
protein ubiquitination GO:0016567 314 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
nucleotide catabolic process GO:0009166 408 0.017
single organism cellular localization GO:1902580 332 0.017
cytokine secretion GO:0050663 64 0.017
hormone metabolic process GO:0042445 61 0.017
protein targeting to nucleus GO:0044744 104 0.017
rhythmic behavior GO:0007622 2 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
carboxylic acid biosynthetic process GO:0046394 97 0.017
protein localization to organelle GO:0033365 280 0.017
somatic muscle development GO:0007525 1 0.017
negative regulation of ion transmembrane transport GO:0034766 26 0.017
ribonucleotide biosynthetic process GO:0009260 81 0.016
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.016
central nervous system development GO:0007417 123 0.016
skin development GO:0043588 76 0.016
oocyte differentiation GO:0009994 2 0.016
dephosphorylation GO:0016311 209 0.016
myoblast fusion GO:0007520 1 0.016
pattern recognition receptor signaling pathway GO:0002221 48 0.016
apoptotic mitochondrial changes GO:0008637 57 0.016
intracellular protein transport GO:0006886 270 0.016
positive regulation of catabolic process GO:0009896 310 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
cell projection morphogenesis GO:0048858 129 0.016
organophosphate ester transport GO:0015748 32 0.016
histone h3 acetylation GO:0043966 45 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
oxidation reduction process GO:0055114 396 0.016
sulfur compound metabolic process GO:0006790 101 0.016
extrinsic apoptotic signaling pathway GO:0097191 119 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
wnt signaling pathway GO:0016055 156 0.015
tripartite regional subdivision GO:0007351 2 0.015
negative regulation of protein maturation GO:1903318 142 0.015
regulation of adaptive immune response GO:0002819 33 0.015
organophosphate catabolic process GO:0046434 430 0.015
organ formation GO:0048645 3 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
regulation of nervous system development GO:0051960 88 0.015
protein polyubiquitination GO:0000209 110 0.015
negative regulation of protein transport GO:0051224 75 0.015
lipid modification GO:0030258 84 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
aging GO:0007568 66 0.015
Rat Worm
regulation of lipid transport GO:0032368 44 0.015
Human
mitotic cell cycle phase transition GO:0044772 162 0.015
protein import GO:0017038 130 0.015
lipid storage GO:0019915 28 0.015
Human Worm
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
reproductive process GO:0022414 106 0.015
Worm
cellular response to lipopolysaccharide GO:0071222 57 0.015
nuclear migration GO:0007097 1 0.015
negative regulation of secretion GO:0051048 58 0.015
Mouse
cell part morphogenesis GO:0032990 137 0.015
cell cycle phase transition GO:0044770 173 0.015
regulation of calcium ion transport GO:0051924 79 0.015
response to nitrogen compound GO:1901698 184 0.015
Mouse Rat
inorganic cation transmembrane transport GO:0098662 194 0.015
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.015
response to starvation GO:0042594 59 0.015
Mouse Rat
receptor mediated endocytosis GO:0006898 84 0.015
cellular response to molecule of bacterial origin GO:0071219 62 0.014
mitochondrion organization GO:0007005 156 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
negative regulation of cell death GO:0060548 345 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
system process GO:0003008 349 0.014
Mouse
establishment of protein localization to organelle GO:0072594 172 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
Human Mouse
positive regulation of cell differentiation GO:0045597 211 0.014
growth of symbiont in host GO:0044117 1 0.014
calcium ion transport GO:0006816 147 0.014
canonical wnt signaling pathway GO:0060070 116 0.014
retrograde transport endosome to golgi GO:0042147 45 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.014
negative regulation of growth of symbiont in host GO:0044130 1 0.014
hemopoiesis GO:0030097 180 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
protein modification by small protein removal GO:0070646 92 0.014
cholesterol efflux GO:0033344 28 0.014
Human
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.014
response to lipopolysaccharide GO:0032496 70 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
ras protein signal transduction GO:0007265 73 0.014
movement in host environment GO:0052126 25 0.014
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
Mouse
morphogenesis of a polarized epithelium GO:0001738 3 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
glucose metabolic process GO:0006006 45 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
cellular amide metabolic process GO:0043603 69 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
regulation of myeloid cell differentiation GO:0045637 81 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
cellular lipid catabolic process GO:0044242 65 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
spermatid development GO:0007286 4 0.014
negative regulation of protein processing GO:0010955 142 0.014
organic hydroxy compound biosynthetic process GO:1901617 71 0.014
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.014
Mouse Rat
regulation of cell cycle phase transition GO:1901987 126 0.014
positive regulation of response to external stimulus GO:0032103 88 0.014
establishment of protein localization to membrane GO:0090150 121 0.013
axis elongation GO:0003401 4 0.013
cellular response to lipid GO:0071396 127 0.013
Rat
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
positive regulation of growth GO:0045927 58 0.013
Worm
negative regulation of cytokine production GO:0001818 82 0.013
alcohol biosynthetic process GO:0046165 52 0.013
Mouse
covalent chromatin modification GO:0016569 254 0.013
Mouse
purine nucleotide catabolic process GO:0006195 405 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
protein localization to membrane GO:0072657 160 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
cytokinesis GO:0000910 96 0.013
viral release from host cell GO:0019076 21 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
negative regulation of protein catabolic process GO:0042177 59 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
nucleus localization GO:0051647 1 0.013
regulation of neurogenesis GO:0050767 82 0.013
regulation of lipid biosynthetic process GO:0046890 47 0.013
Mouse
regulation of protein ubiquitination GO:0031396 95 0.013
epidermis morphogenesis GO:0048730 3 0.013
neurological system process GO:0050877 163 0.013
macroautophagy GO:0016236 39 0.013
positive regulation of neural precursor cell proliferation GO:2000179 2 0.013
response to hyperoxia GO:0055093 4 0.013
response to lipid GO:0033993 206 0.013
Rat
regulation of protein catabolic process GO:0042176 155 0.013
spermatid differentiation GO:0048515 4 0.013
cation transmembrane transport GO:0098655 238 0.013
plasma membrane organization GO:0007009 115 0.013
osteoblast differentiation GO:0001649 92 0.013
metencephalon development GO:0022037 2 0.013
tube closure GO:0060606 3 0.013
sex differentiation GO:0007548 45 0.013
Worm
regulation of feeding behavior GO:0060259 3 0.013
g1 s transition of mitotic cell cycle GO:0000082 78 0.013
entry into other organism involved in symbiotic interaction GO:0051828 25 0.013
ion homeostasis GO:0050801 230 0.013
heart formation GO:0060914 2 0.013
multi organism reproductive process GO:0044703 54 0.012
activation of immune response GO:0002253 114 0.012
cell projection organization GO:0030030 252 0.012
hexose metabolic process GO:0019318 55 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
negative regulation of locomotion GO:0040013 118 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regulation of binding GO:0051098 111 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.012
phospholipid metabolic process GO:0006644 99 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
establishment of nucleus localization GO:0040023 1 0.012
vesicle organization GO:0016050 62 0.012
secretion GO:0046903 254 0.012
Mouse
fat cell differentiation GO:0045444 32 0.012
somatic stem cell maintenance GO:0035019 4 0.012
embryonic placenta development GO:0001892 1 0.012
positive regulation of immune effector process GO:0002699 40 0.012
small molecule catabolic process GO:0044282 92 0.012
response to inorganic substance GO:0010035 127 0.012
thymus development GO:0048538 3 0.012
ossification GO:0001503 121 0.012
cellular response to oxygen levels GO:0071453 55 0.012
growth of symbiont involved in interaction with host GO:0044116 2 0.012
purine ribonucleotide biosynthetic process GO:0009152 79 0.012
neural tube closure GO:0001843 3 0.012
negative regulation of cholesterol transport GO:0032375 8 0.012
Human
nucleoside phosphate biosynthetic process GO:1901293 109 0.012
negative regulation of transmembrane transport GO:0034763 29 0.012
regulation of multi organism process GO:0043900 157 0.012
specification of organ identity GO:0010092 3 0.012
amide biosynthetic process GO:0043604 15 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
calcium ion import GO:0070509 23 0.012
response to increased oxygen levels GO:0036296 4 0.012
heart development GO:0007507 95 0.012
response to metal ion GO:0010038 84 0.012
somitogenesis GO:0001756 2 0.012
cation transport GO:0006812 331 0.012
developmental process involved in reproduction GO:0003006 66 0.012
Worm
regulation of phosphatase activity GO:0010921 81 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
circulatory system process GO:0003013 113 0.011
Mouse
dna repair GO:0006281 198 0.011
rna interference GO:0016246 4 0.011
positive regulation of defense response GO:0031349 87 0.011

SREBF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.073
inherited metabolic disorder DOID:655 242 0.061
nervous system disease DOID:863 431 0.037
neuropathy DOID:870 52 0.037
muscular disease DOID:0080000 114 0.033
musculoskeletal system disease DOID:17 223 0.033
neuromuscular disease DOID:440 38 0.027
myopathy DOID:423 104 0.024
muscle tissue disease DOID:66 113 0.024
charcot marie tooth disease DOID:10595 33 0.021
central nervous system disease DOID:331 186 0.018
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
cardiovascular system disease DOID:1287 106 0.015
sensory system disease DOID:0050155 203 0.014
muscular dystrophy DOID:9884 51 0.014
organ system cancer DOID:0050686 164 0.013
emery dreifuss muscular dystrophy DOID:11726 6 0.012
carbohydrate metabolic disorder DOID:2978 55 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
connective tissue disease DOID:65 109 0.012
neurodegenerative disease DOID:1289 102 0.012
congenital muscular dystrophy DOID:0050557 22 0.012
heart disease DOID:114 68 0.012