|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.991
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.990
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.970
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.942
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.920
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.901
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.879
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.862
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.857
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.829
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.826
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.822
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.818
|
Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.813
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.787
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.768
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.766
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.707
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.707
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.699
|
|
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
2 |
0.675
|
|
|
|
positive regulation of smoothened signaling pathway
|
GO:0045880 |
4 |
0.659
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.623
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.619
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.616
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.611
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.602
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.592
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.580
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.572
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.570
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.567
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.554
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.542
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.540
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.523
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.517
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.513
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.477
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.471
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.467
|
Fly |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.463
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.451
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.418
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.394
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.383
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.358
|
Fly |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.356
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.351
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.347
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.332
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.329
|
Fly |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.329
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.323
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.308
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
2 |
0.304
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.302
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.301
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.299
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.298
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.292
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.292
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.285
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.281
|
Fly |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.279
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.267
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.267
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.259
|
|
|
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.258
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.257
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.244
|
|
|
|
cortical cytoskeleton organization
|
GO:0030865 |
9 |
0.237
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.230
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.230
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.227
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.227
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.227
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.216
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.206
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.206
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.203
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.202
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.201
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.199
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.195
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.195
|
|
|
|
apical junction assembly
|
GO:0043297 |
19 |
0.193
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.191
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.189
|
Worm |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.188
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.180
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.177
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.174
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.171
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.166
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.165
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.165
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.164
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.161
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.158
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.157
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.156
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.151
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.150
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.150
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.149
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.149
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.148
|
|
|
|
protein k29 linked deubiquitination
|
GO:0035523 |
3 |
0.147
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.146
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.145
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.144
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.143
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.140
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.140
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.135
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.134
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.130
|
Worm |
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.129
|
|
|
|
tube formation
|
GO:0035148 |
10 |
0.126
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.126
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.125
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.123
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.122
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.121
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.120
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.119
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.117
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.117
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.115
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.115
|
Fly |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.115
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.115
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.113
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.113
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.111
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.111
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.109
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.108
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.106
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.106
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.105
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.104
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.101
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.101
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.098
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.098
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.096
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.095
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.094
|
Fly |
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.091
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.091
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.091
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.088
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.087
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.085
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.085
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.085
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.084
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.083
|
|
|
|
epithelial tube formation
|
GO:0072175 |
5 |
0.081
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.081
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.080
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.080
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.079
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.079
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.078
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.074
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.074
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.073
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.073
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.073
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.073
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.071
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.071
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.070
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.070
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.069
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.069
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.069
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.069
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.067
|
Fly |
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.066
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.064
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.064
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.064
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.063
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.062
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.062
|
|
|
|
golgi localization
|
GO:0051645 |
4 |
0.061
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.061
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.061
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.060
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.060
|
Fly |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.059
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.059
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.059
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.058
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.058
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.058
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.058
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.057
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.057
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.057
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.056
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.055
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.055
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.055
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.055
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.054
|
Fly |
|
|
digestive system development
|
GO:0055123 |
75 |
0.054
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.053
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.053
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.052
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.052
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.052
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.051
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.051
|
Fly |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.051
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.051
|
Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.051
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.050
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.049
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.049
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.049
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.048
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.047
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.047
|
Worm |
|
|
epithelium development
|
GO:0060429 |
227 |
0.047
|
Fly |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.046
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.046
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.045
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.044
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.044
|
Rat |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.044
|
|
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.044
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.043
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.043
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.043
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.042
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.041
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.041
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.041
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.041
|
Worm |
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.040
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.040
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.039
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.038
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.038
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.038
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.038
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.037
|
Fly |
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.037
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.037
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.037
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.037
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.036
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.036
|
|
|
|
mating
|
GO:0007618 |
1 |
0.036
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.036
|
Fly |
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.036
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.036
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.036
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.035
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.035
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.034
|
|
|
|
centriole replication
|
GO:0007099 |
13 |
0.034
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.034
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.034
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.034
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.033
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.033
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.032
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.032
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.032
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.032
|
Worm |
|
|
secretion
|
GO:0046903 |
254 |
0.032
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.032
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.031
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.031
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.031
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.031
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.031
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.031
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.031
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.031
|
|
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.030
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.030
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.030
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.030
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.030
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.030
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.030
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.029
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.029
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.029
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.029
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.029
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.029
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.029
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.029
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.029
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.029
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.029
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.028
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.028
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.028
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.028
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.028
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.028
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.028
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.028
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.027
|
Rat |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.027
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.027
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.027
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.027
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.027
|
|
|
|
establishment of apical basal cell polarity
|
GO:0035089 |
1 |
0.027
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.026
|
Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.026
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.026
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.026
|
Fly |
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.026
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.026
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.026
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.025
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.025
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.025
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.025
|
|
|
|
negative regulation of epithelial to mesenchymal transition
|
GO:0010719 |
14 |
0.025
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.025
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.025
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.025
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.025
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.025
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.025
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.025
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.024
|
Worm |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.024
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.024
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
15 |
0.024
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.024
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.024
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.024
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.024
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.024
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.024
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.023
|
|
|
|
memory
|
GO:0007613 |
3 |
0.023
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.023
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.023
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.023
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.023
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.023
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.022
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.022
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.022
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.022
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.022
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.022
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.022
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.022
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.022
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.022
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.021
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.021
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.021
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.021
|
|
|
|
inner ear development
|
GO:0048839 |
8 |
0.021
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.021
|
|
|
|
molting cycle
|
GO:0042303 |
28 |
0.021
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.020
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.020
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.020
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.020
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.020
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.020
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.020
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.020
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.019
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.019
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.019
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.019
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.019
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.019
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.019
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.019
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.019
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.019
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.019
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.019
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.019
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.018
|
Worm |
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.018
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.018
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.018
|
|
|
|
aging
|
GO:0007568 |
66 |
0.018
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.018
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.018
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.018
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.018
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.017
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.017
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.017
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.017
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.017
|
Worm |
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
3 |
0.017
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.017
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.017
|
|
|
|
head development
|
GO:0060322 |
108 |
0.017
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.017
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.017
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.017
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.017
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.017
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.017
|
Rat |
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
18 |
0.017
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.017
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.017
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.017
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.017
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
6 |
0.016
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.016
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.016
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.016
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.016
|
|
|
|
cellular response to nerve growth factor stimulus
|
GO:1990090 |
6 |
0.016
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.016
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.016
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.016
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.016
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.016
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.016
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.016
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.016
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.016
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.016
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.016
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.016
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.015
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.015
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.015
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.015
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.015
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.015
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.015
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.015
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.015
|
|
|
|
heart induction
|
GO:0003129 |
4 |
0.015
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.015
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.015
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.015
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.015
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.015
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.015
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.015
|
Fly |
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.014
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.014
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.014
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.014
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.014
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.014
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.014
|
|
|
|
growth
|
GO:0040007 |
202 |
0.014
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.014
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.014
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.014
|
|
|
|
negative regulation of microtubule depolymerization
|
GO:0007026 |
12 |
0.014
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.014
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.014
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.014
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.014
|
|
|
|
regulation of glycoprotein metabolic process
|
GO:1903018 |
19 |
0.014
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.014
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.014
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.013
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.013
|
|
|
|
positive regulation of proteoglycan biosynthetic process
|
GO:1902730 |
3 |
0.013
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.013
|
|
|
|
negative regulation of toll like receptor 3 signaling pathway
|
GO:0034140 |
2 |
0.013
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.013
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.013
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.013
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.013
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.013
|
|
|
|
canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
|
GO:0044334 |
2 |
0.013
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.013
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.013
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.013
|
|
