|
covalent chromatin modification
|
GO:0016569 |
254 |
0.854
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.749
|
|
|
methylation
|
GO:0032259 |
106 |
0.678
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.635
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.566
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.525
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.400
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.347
|
|
|
histone modification
|
GO:0016570 |
251 |
0.315
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.273
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.203
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.177
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.152
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.138
|
|
|
peptidyl lysine dimethylation
|
GO:0018027 |
3 |
0.129
|
Mouse |
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.127
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.123
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.120
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.119
|
|
|
defense response
|
GO:0006952 |
315 |
0.107
|
|
|
regulation of histone h3 k27 methylation
|
GO:0061085 |
4 |
0.094
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.093
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.087
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.084
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.083
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.083
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.069
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.069
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.066
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.062
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.061
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.060
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.058
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.056
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.055
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.054
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.053
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.052
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.049
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.049
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.048
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.047
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.047
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.044
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.044
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
37 |
0.043
|
|
|
negative regulation of histone methylation
|
GO:0031061 |
6 |
0.042
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.040
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.040
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.038
|
|
|
protein dealkylation
|
GO:0008214 |
17 |
0.037
|
|
|
histone demethylation
|
GO:0016577 |
15 |
0.036
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.036
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.036
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.035
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.035
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.035
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.034
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.034
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.034
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.033
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.032
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.031
|
|
|
negative regulation of histone modification
|
GO:0031057 |
19 |
0.031
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.031
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.030
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.030
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.029
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.028
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.028
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.027
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.027
|
|
|
rna processing
|
GO:0006396 |
255 |
0.026
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.025
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.025
|
|
|
system process
|
GO:0003008 |
349 |
0.025
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.024
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.024
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.024
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.024
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.023
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.023
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.023
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.023
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.023
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.023
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.023
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.022
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.022
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.022
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.022
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.021
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.021
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.021
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.021
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.020
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.020
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.020
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.020
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.020
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.020
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.019
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.019
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.019
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.019
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.019
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.019
|
|
|
mrna transport
|
GO:0051028 |
30 |
0.019
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.019
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.018
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.018
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.018
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.018
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.018
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.018
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.018
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.018
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.018
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.018
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.018
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.017
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.017
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.017
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.017
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.017
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.016
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.016
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.016
|
|
|
ossification
|
GO:0001503 |
121 |
0.016
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.016
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.016
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.016
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.016
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.015
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.015
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.015
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.015
|
|
|
segmentation
|
GO:0035282 |
4 |
0.015
|
|
|
regulation of histone methylation
|
GO:0031060 |
16 |
0.015
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.015
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.015
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.015
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.015
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.015
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.015
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.015
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.015
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.014
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.014
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.014
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.014
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.014
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.014
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.014
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.014
|
|
|
sex determination
|
GO:0007530 |
3 |
0.014
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.014
|
Mouse |
|
oogenesis
|
GO:0048477 |
2 |
0.014
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.014
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.013
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.013
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.013
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.013
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.013
|
|
|
neuron death
|
GO:0070997 |
65 |
0.013
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.013
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.013
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.013
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.013
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.013
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.013
|
|
|
mrna export from nucleus
|
GO:0006406 |
29 |
0.012
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.012
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.012
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.012
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.012
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.012
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.012
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.012
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.012
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.012
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.012
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.012
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.012
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.012
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.012
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.012
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.012
|
|
|
neuron development
|
GO:0048666 |
113 |
0.011
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.011
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.011
|
|
|
immune response
|
GO:0006955 |
307 |
0.011
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.011
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.011
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.011
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.011
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.011
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.011
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.011
|
|
|
regeneration
|
GO:0031099 |
4 |
0.011
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.011
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.011
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.011
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.011
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.011
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.011
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.011
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.011
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.011
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.011
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.011
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.011
|
|
|
translation
|
GO:0006412 |
132 |
0.010
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.010
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.010
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.010
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.010
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.010
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.010
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.010
|
|
|
histone h3 k9 demethylation
|
GO:0033169 |
7 |
0.010
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.010
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.010
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.010
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.010
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.010
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.010
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.010
|
|
|
protein import
|
GO:0017038 |
130 |
0.010
|
|
|
memory
|
GO:0007613 |
3 |
0.010
|
|