Homo sapiens

0 known processes

TCEB1

transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)

(Aliases: SIII)

TCEB1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.986
regulation of proteasomal protein catabolic process GO:0061136 87 0.975
cellular macromolecule catabolic process GO:0044265 380 0.973
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.968
positive regulation of catabolic process GO:0009896 310 0.963
protein modification by small protein conjugation GO:0032446 342 0.960
modification dependent protein catabolic process GO:0019941 209 0.958
cellular protein catabolic process GO:0044257 261 0.930
protein catabolic process GO:0030163 325 0.928
proteasomal protein catabolic process GO:0010498 176 0.918
cellular amine metabolic process GO:0044106 41 0.911
regulation of cellular amino acid metabolic process GO:0006521 6 0.899
positive regulation of proteolysis GO:0045862 142 0.898
regulation of cellular protein catabolic process GO:1903362 96 0.892
cell development GO:0048468 328 0.863
Fly
ubiquitin dependent protein catabolic process GO:0006511 206 0.855
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.855
post embryonic development GO:0009791 2 0.847
Worm Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.828
regulation of cell cycle GO:0051726 393 0.822
Worm
positive regulation of protein catabolic process GO:0045732 75 0.820
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.815
regulation of protein catabolic process GO:0042176 155 0.767
nervous system development GO:0007399 293 0.630
Fly
cyclin catabolic process GO:0008054 6 0.624
positive regulation of cellular protein catabolic process GO:1903364 37 0.594
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.539
cellular response to oxygen containing compound GO:1901701 276 0.534
modification dependent macromolecule catabolic process GO:0043632 212 0.531
amine metabolic process GO:0009308 44 0.517
regulation of transferase activity GO:0051338 355 0.513
negative regulation of jak stat cascade GO:0046426 4 0.501
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.466
segmentation GO:0035282 4 0.444
Worm
meiotic chromosome segregation GO:0045132 4 0.404
Worm
microtubule based movement GO:0007018 32 0.386
Worm
regulation of cell cycle process GO:0010564 266 0.385
Worm
female gamete generation GO:0007292 2 0.381
regulation of cellular amine metabolic process GO:0033238 11 0.372
positive regulation of cellular catabolic process GO:0031331 284 0.363
reproductive system development GO:0061458 56 0.361
regulation of cellular ketone metabolic process GO:0010565 50 0.357
protein ubiquitination GO:0016567 314 0.354
regulation of ligase activity GO:0051340 29 0.338
establishment of nucleus localization GO:0040023 1 0.334
regulation of kinase activity GO:0043549 314 0.331
behavior GO:0007610 112 0.327
cellular response to organonitrogen compound GO:0071417 124 0.314
neurogenesis GO:0022008 169 0.310
Fly
mitotic sister chromatid segregation GO:0000070 53 0.306
regulation of proteolysis GO:0030162 293 0.295
regulation of ubiquitin protein transferase activity GO:0051438 28 0.295
positive regulation of hormone biosynthetic process GO:0046886 4 0.291
sister chromatid segregation GO:0000819 54 0.291
Worm
negative regulation of cellular amine metabolic process GO:0033239 3 0.277
negative regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061428 4 0.263
mitotic cell cycle process GO:1903047 286 0.251
multicellular organismal aging GO:0010259 3 0.249
erbb signaling pathway GO:0038127 44 0.245
negative regulation of catalytic activity GO:0043086 335 0.235
epithelial cell migration GO:0010631 119 0.230
regulation of mitotic cell cycle GO:0007346 189 0.229
Worm
embryo development GO:0009790 123 0.225
Worm
regulation of meiotic cell cycle GO:0051445 4 0.209
Worm
cellular response to hormone stimulus GO:0032870 125 0.209
protein targeting GO:0006605 187 0.199
negative regulation of protein kinase activity GO:0006469 98 0.187
positive regulation of meiotic cell cycle GO:0051446 2 0.185
Worm
regulation of cell division GO:0051302 116 0.185
Worm
ameboidal type cell migration GO:0001667 135 0.182
nuclear migration GO:0007097 1 0.179
single organism cellular localization GO:1902580 332 0.179
single organism reproductive process GO:0044702 98 0.175
regulation of protein kinase activity GO:0045859 289 0.164
developmental process involved in reproduction GO:0003006 66 0.164
cell cycle checkpoint GO:0000075 117 0.163
cellular protein complex assembly GO:0043623 188 0.162
negative regulation of protein metabolic process GO:0051248 391 0.158
organ formation GO:0048645 3 0.157
regulation of cellular component biogenesis GO:0044087 281 0.156
cell morphogenesis GO:0000902 296 0.150
Fly
negative regulation of kinase activity GO:0033673 106 0.146
response to lipid GO:0033993 206 0.145
determination of adult lifespan GO:0008340 2 0.142
cellular ketone metabolic process GO:0042180 80 0.134
cellular amino acid metabolic process GO:0006520 116 0.134
negative regulation of mitotic cell cycle GO:0045930 102 0.133
regulation of apoptotic signaling pathway GO:2001233 175 0.132
response to hormone GO:0009725 175 0.129
cellular response to peptide hormone stimulus GO:0071375 56 0.124
response to steroid hormone GO:0048545 80 0.124
nucleus localization GO:0051647 1 0.121
embryo development ending in birth or egg hatching GO:0009792 34 0.119
Worm
cellular macromolecular complex assembly GO:0034622 324 0.118
anterior posterior axis specification embryo GO:0008595 2 0.117
Worm
regulation of sister chromatid segregation GO:0033045 27 0.116
Worm
anterior posterior axis specification GO:0009948 2 0.112
Worm
organelle localization GO:0051640 84 0.110
Worm
single fertilization GO:0007338 11 0.106
cellular response to peptide GO:1901653 59 0.106
growth GO:0040007 202 0.106
oogenesis GO:0048477 2 0.104
response to peptide GO:1901652 65 0.103
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.101
response to estradiol GO:0032355 23 0.100
oocyte differentiation GO:0009994 2 0.098
cellular response to nitrogen compound GO:1901699 144 0.098
positive regulation of cellular component biogenesis GO:0044089 158 0.093
microtubule based process GO:0007017 210 0.090
Worm
neuron differentiation GO:0030182 138 0.087
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.085
reproductive process GO:0022414 106 0.084
negative regulation of apoptotic process GO:0043066 316 0.083
tissue migration GO:0090130 119 0.081
establishment of protein localization to organelle GO:0072594 172 0.080
cullin deneddylation GO:0010388 9 0.080
cytoplasmic transport GO:0016482 379 0.077
regulation of epidermal growth factor activated receptor activity GO:0007176 14 0.075
gonad development GO:0008406 34 0.072
negative regulation of receptor activity GO:2000272 15 0.072
growth hormone receptor signaling pathway GO:0060396 10 0.070
regulation of protein ubiquitination GO:0031396 95 0.069
stem cell differentiation GO:0048863 93 0.069
response to organic cyclic compound GO:0014070 204 0.068
reproductive structure development GO:0048608 55 0.066
protein localization to organelle GO:0033365 280 0.066
mitotic sister chromatid separation GO:0051306 18 0.065
regulation of cellular response to stress GO:0080135 244 0.064
negative regulation of programmed cell death GO:0043069 321 0.064
regulation of mitotic sister chromatid segregation GO:0033047 27 0.064
Worm
actin filament based process GO:0030029 224 0.063
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.063
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.062
positive regulation of developmental process GO:0051094 314 0.061
positive regulation of kinase activity GO:0033674 204 0.060
protein import into mitochondrial matrix GO:0030150 1 0.060
multicellular organism reproduction GO:0032504 42 0.059
protein targeting to nucleus GO:0044744 104 0.059
establishment of organelle localization GO:0051656 59 0.058
Worm
purine nucleoside triphosphate metabolic process GO:0009144 412 0.058
neural crest cell development GO:0014032 3 0.057
regulation of protein stability GO:0031647 87 0.056
chemical homeostasis GO:0048878 306 0.056
blastoderm segmentation GO:0007350 2 0.054
Worm
posttranscriptional regulation of gene expression GO:0010608 213 0.054
response to abiotic stimulus GO:0009628 336 0.053
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.053
regulation of locomotion GO:0040012 329 0.052
organelle fission GO:0048285 149 0.052
Worm
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 9 0.051
intracellular protein transport GO:0006886 270 0.051
cell division GO:0051301 168 0.050
aging GO:0007568 66 0.050
regulation of nuclear division GO:0051783 65 0.050
Worm
neuron projection morphogenesis GO:0048812 50 0.049
Fly
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.049
neuromuscular junction development GO:0007528 3 0.048
mitotic cell cycle checkpoint GO:0007093 68 0.048
protein import into nucleus GO:0006606 104 0.048
alcohol metabolic process GO:0006066 114 0.048
cellular component morphogenesis GO:0032989 314 0.047
Fly
tripartite regional subdivision GO:0007351 2 0.047
Worm
response to growth hormone GO:0060416 11 0.047
multicellular organismal reproductive process GO:0048609 40 0.047
sex differentiation GO:0007548 45 0.047
protein modification by small protein removal GO:0070646 92 0.046
cytokine production GO:0001816 247 0.045
regulation of protein tyrosine kinase activity GO:0061097 36 0.045
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
actin cytoskeleton organization GO:0030036 207 0.043
cell type specific apoptotic process GO:0097285 125 0.042
meiosis i GO:0007127 4 0.042
stem cell development GO:0048864 69 0.041
negative regulation of phosphate metabolic process GO:0045936 267 0.041
fertilization GO:0009566 12 0.041
response to alcohol GO:0097305 64 0.041
response to peptide hormone GO:0043434 61 0.040
positive regulation of transferase activity GO:0051347 227 0.040
cytokinesis GO:0000910 96 0.039
circulatory system development GO:0072359 262 0.038
single organism nuclear import GO:1902593 104 0.038
neuron development GO:0048666 113 0.038
Fly
peptidyl tyrosine modification GO:0018212 170 0.037
stress activated protein kinase signaling cascade GO:0031098 94 0.037
negative regulation of protein phosphorylation GO:0001933 140 0.037
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.037
response to oxygen containing compound GO:1901700 369 0.036
organic hydroxy compound metabolic process GO:1901615 147 0.036
response to organonitrogen compound GO:0010243 156 0.035
response to nitrogen compound GO:1901698 184 0.035
epithelium migration GO:0090132 119 0.035
organ morphogenesis GO:0009887 147 0.035
Fly
dna integrity checkpoint GO:0031570 71 0.035
positive regulation of cytokine production GO:0001819 167 0.035
mitotic dna integrity checkpoint GO:0044774 30 0.034
negative regulation of intracellular signal transduction GO:1902532 183 0.034
positive regulation of programmed cell death GO:0043068 249 0.034
guanosine containing compound metabolic process GO:1901068 244 0.034
regulation of mitotic cell cycle phase transition GO:1901990 118 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.033
positive regulation of protein kinase activity GO:0045860 190 0.033
enzyme linked receptor protein signaling pathway GO:0007167 303 0.033
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.032
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
secretion GO:0046903 254 0.031
glial cell migration GO:0008347 4 0.031
protein maturation GO:0051604 233 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
positive regulation of phosphorylation GO:0042327 394 0.030
cell cell signaling involved in cell fate commitment GO:0045168 5 0.030
reproduction GO:0000003 63 0.030
Worm
chromosome segregation GO:0007059 114 0.030
Worm
stress activated mapk cascade GO:0051403 93 0.029
exosomal secretion GO:1990182 15 0.029
regulation of jak stat cascade GO:0046425 44 0.029
development of primary sexual characteristics GO:0045137 35 0.029
epidermal growth factor receptor signaling pathway GO:0007173 39 0.028
positive regulation of protein phosphorylation GO:0001934 313 0.028
negative regulation of protein modification process GO:0031400 200 0.028
regulation of cell development GO:0060284 161 0.028
positive regulation of apoptotic process GO:0043065 246 0.028
golgi vesicle transport GO:0048193 80 0.027
cell projection morphogenesis GO:0048858 129 0.027
Fly
cellular response to endogenous stimulus GO:0071495 336 0.027
mitotic nuclear division GO:0007067 119 0.027
response to estrogen GO:0043627 47 0.026
cell fate determination GO:0001709 3 0.026
lipid biosynthetic process GO:0008610 177 0.026
blood vessel morphogenesis GO:0048514 162 0.026
negative regulation of phosphorylation GO:0042326 174 0.025
locomotory behavior GO:0007626 1 0.025
regulation of receptor activity GO:0010469 47 0.025
chemotaxis GO:0006935 157 0.024
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.024
vasculature development GO:0001944 181 0.024
taxis GO:0042330 157 0.024
response to bacterium GO:0009617 144 0.024
protein localization to nucleus GO:0034504 136 0.024
organelle assembly GO:0070925 176 0.024
memory GO:0007613 3 0.024
regulation of meiosis GO:0040020 3 0.024
generation of neurons GO:0048699 152 0.023
Fly
response to inorganic substance GO:0010035 127 0.023
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.023
cell death in response to oxidative stress GO:0036473 29 0.023
cellular response to hypoxia GO:0071456 51 0.023
hindbrain development GO:0030902 3 0.023
negative regulation of developmental process GO:0051093 247 0.023
regulation of mitosis GO:0007088 63 0.022
Worm
regionalization GO:0003002 29 0.022
Worm Fly
regulation of nucleotide metabolic process GO:0006140 269 0.022
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.021
activation of janus kinase activity GO:0042976 7 0.021
negative regulation of cellular protein catabolic process GO:1903363 38 0.021
regulation of map kinase activity GO:0043405 108 0.021
negative regulation of cell cycle GO:0045786 193 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
ribonucleoprotein complex assembly GO:0022618 78 0.020
regulation of cytokine secretion GO:0050707 57 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.020
mitotic cell cycle phase transition GO:0044772 162 0.019
negative regulation of transferase activity GO:0051348 124 0.019
regulation of protein transport GO:0051223 213 0.019
neural crest cell migration GO:0001755 2 0.019
long term memory GO:0007616 2 0.019
cellular response to growth hormone stimulus GO:0071378 10 0.019
regulation of erbb signaling pathway GO:1901184 27 0.019
mitotic cell cycle GO:0000278 326 0.018
regulation of cellular component movement GO:0051270 334 0.018
blood vessel development GO:0001568 172 0.018
organonitrogen compound biosynthetic process GO:1901566 200 0.018
cell projection organization GO:0030030 252 0.018
Fly
cellular homeostasis GO:0019725 196 0.018
activation of protein kinase activity GO:0032147 90 0.018
negative regulation of cell death GO:0060548 345 0.017
transmembrane transport GO:0055085 399 0.017
regulation of activation of jak2 kinase activity GO:0010534 5 0.017
regulation of mitotic spindle checkpoint GO:1903504 8 0.017
chromosome separation GO:0051304 23 0.017
autophagy GO:0006914 88 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
nuclear import GO:0051170 106 0.017
mesenchymal cell development GO:0014031 50 0.017
hemopoiesis GO:0030097 180 0.016
negative regulation of protein tyrosine kinase activity GO:0061099 13 0.016
regulation of anatomical structure size GO:0090066 101 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
negative regulation of protein catabolic process GO:0042177 59 0.016
establishment of chromosome localization GO:0051303 20 0.016
Worm
regulation of protein localization GO:0032880 296 0.016
glycerophospholipid metabolic process GO:0006650 84 0.016
nls bearing protein import into nucleus GO:0006607 2 0.016
cytokine secretion GO:0050663 64 0.015
protein secretion GO:0009306 98 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
regulation of secretion by cell GO:1903530 177 0.015
system process GO:0003008 349 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
neuron projection development GO:0031175 106 0.015
Fly
sexual reproduction GO:0019953 37 0.015
thymocyte apoptotic process GO:0070242 2 0.015
negative regulation of proteolysis GO:0045861 132 0.015
inflammatory response GO:0006954 79 0.015
negative regulation of epidermal growth factor activated receptor activity GO:0007175 6 0.015
stem cell division GO:0017145 2 0.015
nuclear transport GO:0051169 179 0.015
protein import GO:0017038 130 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
response to external biotic stimulus GO:0043207 261 0.014
protein polyubiquitination GO:0000209 110 0.014
secretion by cell GO:0032940 226 0.014
cell cycle phase transition GO:0044770 173 0.014
Worm
multi organism reproductive process GO:0044703 54 0.014
actin filament organization GO:0007015 128 0.014
striated muscle tissue development GO:0014706 59 0.014
neurotransmitter gated ion channel clustering GO:0072578 1 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
small molecule biosynthetic process GO:0044283 157 0.013
nucleotide catabolic process GO:0009166 408 0.013
jnk cascade GO:0007254 80 0.013
protein polymerization GO:0051258 71 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
response to other organism GO:0051707 261 0.013
multicellular organismal response to stress GO:0033555 1 0.013
mitochondrion organization GO:0007005 156 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
mitotic g2 m transition checkpoint GO:0044818 9 0.013
regulation of mitotic sister chromatid separation GO:0010965 27 0.012
Worm
single organism behavior GO:0044708 28 0.012
positive regulation of nervous system development GO:0051962 54 0.012
regulation of neuron death GO:1901214 56 0.012
epithelial cell development GO:0002064 34 0.012
negative regulation of thymocyte apoptotic process GO:0070244 1 0.012
hemoglobin metabolic process GO:0020027 3 0.012
phospholipid biosynthetic process GO:0008654 44 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
g2 m transition of mitotic cell cycle GO:0000086 41 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
response to virus GO:0009615 126 0.011
regulation of response to external stimulus GO:0032101 222 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.011
Fly
epithelium development GO:0060429 227 0.011
organophosphate catabolic process GO:0046434 430 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
spindle organization GO:0007051 53 0.011
regulation of cytokine production GO:0001817 232 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
nitrogen compound transport GO:0071705 191 0.011
regulation of chromosome segregation GO:0051983 44 0.011
Worm
response to activity GO:0014823 0 0.011
gtp catabolic process GO:0006184 237 0.011
developmental growth GO:0048589 48 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
meiotic nuclear division GO:0007126 10 0.011
Worm
signal transduction by phosphorylation GO:0023014 297 0.011
cell chemotaxis GO:0060326 112 0.011
negative regulation of immune response GO:0050777 40 0.011
glycosyl compound catabolic process GO:1901658 413 0.010
response to oxygen levels GO:0070482 100 0.010
regulation of actin cytoskeleton organization GO:0032956 116 0.010
regulation of actin filament based process GO:0032970 141 0.010
positive regulation of cell development GO:0010720 92 0.010
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 7 0.010

TCEB1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cell type benign neoplasm DOID:0060084 10 0.139
phaeochromocytoma DOID:0050771 8 0.139
benign neoplasm DOID:0060072 18 0.139
disease of cellular proliferation DOID:14566 174 0.139
inherited metabolic disorder DOID:655 242 0.092
disease of metabolism DOID:0014667 295 0.092
cancer DOID:162 167 0.063
organ system cancer DOID:0050686 164 0.047
urinary system cancer DOID:3996 15 0.047
renal carcinoma DOID:4451 8 0.047
kidney cancer DOID:263 11 0.047
developmental disorder of mental health DOID:0060037 29 0.028
disease of mental health DOID:150 70 0.028
renal cell carcinoma DOID:4450 8 0.023