Homo sapiens

0 known processes

TCEB2

transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)

(Aliases: ELOB,SIII)

TCEB2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
postsynaptic membrane organization GO:0001941 2 0.874
post embryonic development GO:0009791 2 0.718
Worm
ubiquitin dependent protein catabolic process GO:0006511 206 0.587
regulation of mitotic cell cycle phase transition GO:1901990 118 0.577
regulation of proteasomal protein catabolic process GO:0061136 87 0.541
negative regulation of programmed cell death GO:0043069 321 0.491
regulation of protein catabolic process GO:0042176 155 0.485
negative regulation of jak stat cascade GO:0046426 4 0.484
regulation of cellular amino acid metabolic process GO:0006521 6 0.476
modification dependent protein catabolic process GO:0019941 209 0.452
cellular macromolecule catabolic process GO:0044265 380 0.447
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.444
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.436
protein catabolic process GO:0030163 325 0.426
cellular protein catabolic process GO:0044257 261 0.421
cellular response to oxygen containing compound GO:1901701 276 0.419
protein modification by small protein conjugation GO:0032446 342 0.412
cellular amino acid metabolic process GO:0006520 116 0.400
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.385
chromosome separation GO:0051304 23 0.377
protein ubiquitination GO:0016567 314 0.373
cellular component morphogenesis GO:0032989 314 0.362
regulation of cell cycle GO:0051726 393 0.326
neurogenesis GO:0022008 169 0.298
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.282
cellular amine metabolic process GO:0044106 41 0.267
positive regulation of proteolysis GO:0045862 142 0.260
regulation of proteolysis GO:0030162 293 0.251
tripartite regional subdivision GO:0007351 2 0.243
cell projection organization GO:0030030 252 0.236
mitotic sister chromatid separation GO:0051306 18 0.236
proteasomal protein catabolic process GO:0010498 176 0.233
negative regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061428 4 0.227
organelle fission GO:0048285 149 0.226
positive regulation of catabolic process GO:0009896 310 0.225
positive regulation of protein catabolic process GO:0045732 75 0.206
regulation of actin cytoskeleton organization GO:0032956 116 0.197
regulation of cellular component biogenesis GO:0044087 281 0.197
positive regulation of meiotic cell cycle GO:0051446 2 0.192
mitotic cell cycle process GO:1903047 286 0.191
regulation of sister chromatid segregation GO:0033045 27 0.186
regulation of meiotic cell cycle GO:0051445 4 0.174
regulation of cellular protein catabolic process GO:1903362 96 0.173
embryo development ending in birth or egg hatching GO:0009792 34 0.169
Worm
segmentation GO:0035282 4 0.169
negative regulation of protein metabolic process GO:0051248 391 0.158
tissue migration GO:0090130 119 0.151
cellular response to endogenous stimulus GO:0071495 336 0.149
nuclear migration GO:0007097 1 0.148
response to lipid GO:0033993 206 0.146
actin filament based process GO:0030029 224 0.144
regulation of cell cycle phase transition GO:1901987 126 0.142
mitotic cell cycle GO:0000278 326 0.140
regulation of cellular amine metabolic process GO:0033238 11 0.140
cell cycle phase transition GO:0044770 173 0.140
cell development GO:0048468 328 0.137
regulation of cell cycle process GO:0010564 266 0.134
regulation of ligase activity GO:0051340 29 0.133
regulation of cellular ketone metabolic process GO:0010565 50 0.133
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.132
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.131
regulation of apoptotic signaling pathway GO:2001233 175 0.129
nervous system development GO:0007399 293 0.122
regulation of cell division GO:0051302 116 0.120
amine metabolic process GO:0009308 44 0.119
negative regulation of catalytic activity GO:0043086 335 0.114
negative regulation of cell death GO:0060548 345 0.113
meiotic chromosome segregation GO:0045132 4 0.113
regulation of transferase activity GO:0051338 355 0.107
positive regulation of cell cycle GO:0045787 140 0.105
peptidyl tyrosine modification GO:0018212 170 0.105
cellular ketone metabolic process GO:0042180 80 0.103
regulation of mitotic sister chromatid separation GO:0010965 27 0.099
regulation of ubiquitin protein transferase activity GO:0051438 28 0.099
multicellular organismal aging GO:0010259 3 0.096
positive regulation of arp2 3 complex mediated actin nucleation GO:2000601 5 0.095
anterior posterior axis specification embryo GO:0008595 2 0.095
mitotic sister chromatid segregation GO:0000070 53 0.095
epithelial cell migration GO:0010631 119 0.092
embryo development GO:0009790 123 0.091
Worm
regulation of mitotic cell cycle GO:0007346 189 0.091
actin cytoskeleton organization GO:0030036 207 0.090
thymocyte apoptotic process GO:0070242 2 0.090
sister chromatid segregation GO:0000819 54 0.089
epithelium migration GO:0090132 119 0.089
female gamete generation GO:0007292 2 0.088
negative regulation of developmental process GO:0051093 247 0.088
determination of adult lifespan GO:0008340 2 0.084
positive regulation of cell cycle process GO:0090068 106 0.084
regulation of nuclear division GO:0051783 65 0.084
negative regulation of wnt signaling pathway GO:0030178 69 0.082
metaphase anaphase transition of cell cycle GO:0044784 21 0.082
negative regulation of multicellular organismal process GO:0051241 317 0.081
regulation of mitotic sister chromatid segregation GO:0033047 27 0.080
modification dependent macromolecule catabolic process GO:0043632 212 0.080
positive regulation of cellular catabolic process GO:0031331 284 0.079
microtubule based movement GO:0007018 32 0.079
negative regulation of apoptotic process GO:0043066 316 0.077
regulation of anatomical structure size GO:0090066 101 0.077
cell projection morphogenesis GO:0048858 129 0.075
endothelial cell migration GO:0043542 86 0.075
blastoderm segmentation GO:0007350 2 0.073
cell morphogenesis GO:0000902 296 0.073
growth GO:0040007 202 0.070
vesicle organization GO:0016050 62 0.069
anterior posterior axis specification GO:0009948 2 0.069
response to oxygen containing compound GO:1901700 369 0.068
taxis GO:0042330 157 0.066
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.065
cardiovascular system development GO:0072358 262 0.064
circulatory system development GO:0072359 262 0.064
cytoplasmic transport GO:0016482 379 0.064
regulation of mitosis GO:0007088 63 0.063
cell part morphogenesis GO:0032990 137 0.061
regulation of lamellipodium morphogenesis GO:2000392 4 0.061
wnt signaling pathway GO:0016055 156 0.060
negative regulation of cell cycle GO:0045786 193 0.059
regulation of kinase activity GO:0043549 314 0.059
neuron development GO:0048666 113 0.059
mitotic cell cycle phase transition GO:0044772 162 0.058
regulation of protein kinase activity GO:0045859 289 0.058
response to estradiol GO:0032355 23 0.057
peptidyl tyrosine phosphorylation GO:0018108 170 0.057
cell cycle checkpoint GO:0000075 117 0.057
regulation of cell differentiation GO:0045595 393 0.057
generation of neurons GO:0048699 152 0.056
long term memory GO:0007616 2 0.054
negative regulation of phosphorus metabolic process GO:0010563 267 0.054
wound healing GO:0042060 115 0.054
negative regulation of mitotic cell cycle GO:0045930 102 0.053
regulation of protein ubiquitination GO:0031396 95 0.053
cellular response to peptide hormone stimulus GO:0071375 56 0.053
positive regulation of cellular protein catabolic process GO:1903364 37 0.052
negative regulation of phosphorylation GO:0042326 174 0.052
lipid localization GO:0010876 106 0.052
regulation of actin filament based process GO:0032970 141 0.052
negative regulation of t cell apoptotic process GO:0070233 4 0.052
establishment of nucleus localization GO:0040023 1 0.051
cellular protein complex assembly GO:0043623 188 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.051
ameboidal type cell migration GO:0001667 135 0.051
regulation of chromosome segregation GO:0051983 44 0.050
regulation of chromosome organization GO:0033044 103 0.049
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.048
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.048
negative regulation of intracellular signal transduction GO:1902532 183 0.047
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.047
nuclear division GO:0000280 128 0.046
chromosome segregation GO:0007059 114 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
positive regulation of developmental process GO:0051094 314 0.045
negative regulation of cellular amine metabolic process GO:0033239 3 0.044
regulation of reactive oxygen species metabolic process GO:2000377 41 0.043
chemotaxis GO:0006935 157 0.043
positive regulation of protein complex assembly GO:0031334 86 0.043
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.043
enzyme linked receptor protein signaling pathway GO:0007167 303 0.042
cellular lipid metabolic process GO:0044255 303 0.041
mitotic cell cycle checkpoint GO:0007093 68 0.040
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.040
negative regulation of kinase activity GO:0033673 106 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
organelle assembly GO:0070925 176 0.039
mitochondrion organization GO:0007005 156 0.038
nucleus localization GO:0051647 1 0.037
cell division GO:0051301 168 0.036
mitotic nuclear division GO:0007067 119 0.036
rna interference GO:0016246 4 0.036
inflammatory response GO:0006954 79 0.036
negative regulation of cell differentiation GO:0045596 171 0.035
blood vessel morphogenesis GO:0048514 162 0.035
protein localization to membrane GO:0072657 160 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.034
positive regulation of cellular component biogenesis GO:0044089 158 0.034
signal transduction by phosphorylation GO:0023014 297 0.034
membrane organization GO:0061024 292 0.034
negative regulation of transferase activity GO:0051348 124 0.033
intracellular protein transport GO:0006886 270 0.033
cell morphogenesis involved in differentiation GO:0000904 144 0.033
microtubule based process GO:0007017 210 0.032
vacuole organization GO:0007033 44 0.030
response to organonitrogen compound GO:0010243 156 0.030
neuron projection morphogenesis GO:0048812 50 0.030
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 7 0.030
regulation of cytoskeleton organization GO:0051493 177 0.030
negative regulation of protein phosphorylation GO:0001933 140 0.030
positive regulation of protein kinase activity GO:0045860 190 0.029
positive regulation of cellular component organization GO:0051130 376 0.029
positive regulation of nucleotide metabolic process GO:0045981 230 0.029
regulation of cell morphogenesis GO:0022604 153 0.028
posttranscriptional regulation of gene expression GO:0010608 213 0.028
cellular response to cytokine stimulus GO:0071345 181 0.028
negative regulation of cell cycle phase transition GO:1901988 89 0.028
positive regulation of kinase activity GO:0033674 204 0.028
neuron differentiation GO:0030182 138 0.027
peptidyl lysine modification GO:0018205 144 0.027
regulation of protein complex assembly GO:0043254 147 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
positive regulation of hormone biosynthetic process GO:0046886 4 0.026
neuron projection development GO:0031175 106 0.026
cellular response to organonitrogen compound GO:0071417 124 0.026
peptidyl lysine acetylation GO:0018394 101 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
negative regulation of response to external stimulus GO:0032102 83 0.026
vesicle mediated transport GO:0016192 371 0.026
negative regulation of protein modification process GO:0031400 200 0.026
protein localization to organelle GO:0033365 280 0.026
cytokine production GO:0001816 247 0.025
oogenesis GO:0048477 2 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
neuromuscular junction development GO:0007528 3 0.024
cellular response to reactive oxygen species GO:0034614 50 0.024
protein targeting GO:0006605 187 0.024
positive regulation of cell projection organization GO:0031346 64 0.024
regulation of cellular component size GO:0032535 82 0.024
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.023
regulation of cell projection organization GO:0031344 107 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.023
response to nitrogen compound GO:1901698 184 0.023
negative regulation of protein kinase activity GO:0006469 98 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
regulation of receptor activity GO:0010469 47 0.023
positive regulation of programmed cell death GO:0043068 249 0.022
mitotic dna integrity checkpoint GO:0044774 30 0.022
regulation of neuroblast proliferation GO:1902692 3 0.022
g2 m transition of mitotic cell cycle GO:0000086 41 0.022
negative regulation of receptor activity GO:2000272 15 0.021
aging GO:0007568 66 0.021
negative regulation of growth GO:0045926 97 0.021
response to peptide GO:1901652 65 0.021
cellular response to nitrogen compound GO:1901699 144 0.020
cell type specific apoptotic process GO:0097285 125 0.020
regulation of erbb signaling pathway GO:1901184 27 0.020
protein acetylation GO:0006473 116 0.020
neuroblast proliferation GO:0007405 4 0.020
regulation of protein polymerization GO:0032271 63 0.020
cellular response to peptide GO:1901653 59 0.020
dna integrity checkpoint GO:0031570 71 0.020
cellular response to lipid GO:0071396 127 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
response to organic cyclic compound GO:0014070 204 0.019
cell fate determination GO:0001709 3 0.019
actin filament organization GO:0007015 128 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
regulation of canonical wnt signaling pathway GO:0060828 88 0.018
negative regulation of actin nucleation GO:0051126 3 0.018
neurotransmitter gated ion channel clustering GO:0072578 1 0.018
immune response GO:0006955 307 0.018
meiosis i GO:0007127 4 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
regulation of body fluid levels GO:0050878 99 0.018
negative regulation of arp2 3 complex mediated actin nucleation GO:0034316 1 0.017
oxidation reduction process GO:0055114 396 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
cyclin catabolic process GO:0008054 6 0.017
spindle elongation GO:0051231 4 0.017
membrane hyperpolarization GO:0060081 1 0.017
regulation of cell growth GO:0001558 135 0.017
regulation of cellular component movement GO:0051270 334 0.016
cell chemotaxis GO:0060326 112 0.016
response to bacterium GO:0009617 144 0.016
epidermal growth factor receptor signaling pathway GO:0007173 39 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
regulation of response to external stimulus GO:0032101 222 0.016
hemopoiesis GO:0030097 180 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
memory GO:0007613 3 0.016
negative regulation of retinoic acid receptor signaling pathway GO:0048387 4 0.016
actin filament polymerization GO:0030041 45 0.016
mapk cascade GO:0000165 288 0.015
regulation of lymphocyte apoptotic process GO:0070228 15 0.015
regeneration GO:0031099 4 0.015
reproductive process GO:0022414 106 0.015
Worm
wound healing involved in inflammatory response GO:0002246 2 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
retina vasculature development in camera type eye GO:0061298 3 0.015
negative regulation of thymocyte apoptotic process GO:0070244 1 0.015
single organism reproductive process GO:0044702 98 0.015
Worm
response to peptide hormone GO:0043434 61 0.015
dna repair GO:0006281 198 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.014
regulation of map kinase activity GO:0043405 108 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
regulation of actin filament polymerization GO:0030833 50 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
response to hypoxia GO:0001666 96 0.014
regulation of actin polymerization or depolymerization GO:0008064 56 0.014
response to steroid hormone GO:0048545 80 0.014
regulation of gtpase activity GO:0043087 180 0.014
immune system development GO:0002520 195 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
regulation of epidermal growth factor activated receptor activity GO:0007176 14 0.014
protein maturation GO:0051604 233 0.014
regulation of cellular response to stress GO:0080135 244 0.014
developmental process involved in reproduction GO:0003006 66 0.013
Worm
positive regulation of gtpase activity GO:0043547 166 0.013
nuclear transport GO:0051169 179 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
negative regulation of immune system process GO:0002683 136 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
regulation of mapk cascade GO:0043408 262 0.013
actin polymerization or depolymerization GO:0008154 56 0.013
regulation of jak stat cascade GO:0046425 44 0.013
regulation of locomotion GO:0040012 329 0.013
exocytosis GO:0006887 71 0.013
hypoxia inducible factor 1alpha signaling pathway GO:0097411 3 0.013
regulation of growth GO:0040008 165 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
autophagy GO:0006914 88 0.013
cytokinesis GO:0000910 96 0.013
lymphocyte apoptotic process GO:0070227 20 0.013
cellular response to external stimulus GO:0071496 111 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
cell adhesion GO:0007155 325 0.013
gas homeostasis GO:0033483 4 0.013
regulation of cell migration GO:0030334 289 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.013
regulation of gtp catabolic process GO:0033124 180 0.012
receptor mediated endocytosis GO:0006898 84 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of cell development GO:0060284 161 0.012
defense response GO:0006952 315 0.012
regulation of cell cycle g2 m phase transition GO:1902749 22 0.012
establishment of organelle localization GO:0051656 59 0.012
protein oligomerization GO:0051259 173 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
actin filament bundle assembly GO:0051017 54 0.012
cellular cation homeostasis GO:0030003 163 0.012
axon cargo transport GO:0008088 2 0.012
positive regulation of cell cycle phase transition GO:1901989 22 0.012
copper ion homeostasis GO:0055070 3 0.012
vasculature development GO:0001944 181 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.012
maintenance of location GO:0051235 112 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
reproductive system development GO:0061458 56 0.012
Worm
positive regulation of transport GO:0051050 336 0.012
response to auditory stimulus GO:0010996 4 0.012
negative regulation of cell cycle process GO:0010948 121 0.011
response to other organism GO:0051707 261 0.011
anatomical structure homeostasis GO:0060249 100 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
organelle localization GO:0051640 84 0.011
axonogenesis GO:0007409 31 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
axon development GO:0061564 34 0.011
lamellipodium morphogenesis GO:0072673 4 0.011
hemoglobin biosynthetic process GO:0042541 3 0.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.011
positive regulation of neuroblast proliferation GO:0002052 2 0.011
tor signaling GO:0031929 39 0.011
positive regulation of secretion GO:0051047 116 0.011
cellular response to lipopolysaccharide GO:0071222 57 0.011
leukocyte activation GO:0045321 164 0.011
ribonucleotide biosynthetic process GO:0009260 81 0.011
positive regulation of organelle organization GO:0010638 195 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
erbb signaling pathway GO:0038127 44 0.010
regulation of immune response GO:0050776 201 0.010
response to wounding GO:0009611 168 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
negative regulation of proteolysis GO:0045861 132 0.010
leukocyte apoptotic process GO:0071887 31 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
t cell apoptotic process GO:0070231 12 0.010
adult locomotory behavior GO:0008344 1 0.010
regulation of membrane potential GO:0042391 95 0.010
response to decreased oxygen levels GO:0036293 96 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010

TCEB2 disease predictions

Disease DO term ID Size Probability Func Analog Org
kidney cancer DOID:263 11 0.190
urinary system cancer DOID:3996 15 0.190
nonpapillary renal cell carcinoma DOID:0050387 6 0.190
hereditary renal cell carcinoma DOID:4455 6 0.190
renal cell carcinoma DOID:4450 8 0.190
renal carcinoma DOID:4451 8 0.190
cancer DOID:162 167 0.190
disease of cellular proliferation DOID:14566 174 0.190
organ system cancer DOID:0050686 164 0.190
phaeochromocytoma DOID:0050771 8 0.015
cell type benign neoplasm DOID:0060084 10 0.015
benign neoplasm DOID:0060072 18 0.015