Homo sapiens

0 known processes

TCP1

t-complex 1

(Aliases: TCP-1-alpha,CCT1,CCT-alpha,D6S230E,CCTa)

TCP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell recognition GO:0009988 4 1.000
Mouse
protein folding GO:0006457 38 1.000
Yeast
binding of sperm to zona pellucida GO:0007339 3 1.000
Mouse
sperm egg recognition GO:0035036 3 1.000
Mouse
establishment or maintenance of neuroblast polarity GO:0045196 1 0.997
spindle assembly involved in mitosis GO:0090307 12 0.996
Fly
asymmetric neuroblast division GO:0055059 1 0.996
post embryonic development GO:0009791 2 0.993
Worm
neuroblast division GO:0055057 1 0.992
neuronal stem cell division GO:0036445 1 0.980
regulation of proteasomal protein catabolic process GO:0061136 87 0.970
regulation of mitotic sister chromatid separation GO:0010965 27 0.941
mitochondrion organization GO:0007005 156 0.940
regulation of neuroblast proliferation GO:1902692 3 0.928
toxin transport GO:1901998 4 0.911
Mouse
organelle assembly GO:0070925 176 0.883
Fly
embryo development GO:0009790 123 0.867
Worm
single fertilization GO:0007338 11 0.865
Mouse
protein processing GO:0016485 226 0.851
fertilization GO:0009566 12 0.818
Mouse
mitotic nuclear division GO:0007067 119 0.805
Fly
negative regulation of protein maturation GO:1903318 142 0.781
neuroblast proliferation GO:0007405 4 0.772
determination of adult lifespan GO:0008340 2 0.767
negative regulation of cellular component organization GO:0051129 235 0.744
de novo protein folding GO:0006458 2 0.743
protein localization to organelle GO:0033365 280 0.740
organelle fission GO:0048285 149 0.729
Fly
regulation of cell cycle GO:0051726 393 0.721
mitotic cell cycle GO:0000278 326 0.717
Fly
mitotic cell cycle process GO:1903047 286 0.713
Fly
mitotic spindle organization GO:0007052 27 0.693
Fly
microtubule based process GO:0007017 210 0.691
Fly
cell development GO:0048468 328 0.684
negative regulation of multicellular organismal process GO:0051241 317 0.678
microtubule cytoskeleton organization GO:0000226 176 0.663
Fly
microtubule organizing center organization GO:0031023 62 0.628
negative regulation of neural precursor cell proliferation GO:2000178 1 0.619
mitochondrial transport GO:0006839 60 0.586
negative regulation of cytokinesis GO:0032466 3 0.571
spindle assembly GO:0051225 29 0.555
Fly
asymmetric stem cell division GO:0098722 1 0.550
regulation of proteolysis GO:0030162 293 0.538
multicellular organismal aging GO:0010259 3 0.537
cytoskeleton dependent cytokinesis GO:0061640 22 0.526
positive regulation of hydrolase activity GO:0051345 331 0.489
regulation of protein localization GO:0032880 296 0.486
regulation of locomotion GO:0040012 329 0.484
protein refolding GO:0042026 14 0.462
oogenesis GO:0048477 2 0.461
proteasomal protein catabolic process GO:0010498 176 0.459
negative regulation of stem cell proliferation GO:2000647 3 0.451
negative regulation of neurogenesis GO:0050768 26 0.448
regulation of cell cycle checkpoint GO:1901976 21 0.427
single organism cellular localization GO:1902580 332 0.406
reproductive process GO:0022414 106 0.364
Mouse Worm
system process GO:0003008 349 0.364
single organism membrane organization GO:0044802 268 0.316
spindle organization GO:0007051 53 0.301
Fly
negative regulation of catabolic process GO:0009895 104 0.297
cellular macromolecule catabolic process GO:0044265 380 0.294
metaphase anaphase transition of cell cycle GO:0044784 21 0.293
response to endoplasmic reticulum stress GO:0034976 49 0.288
negative regulation of cell development GO:0010721 48 0.287
female gamete generation GO:0007292 2 0.274
negative regulation of cell proliferation GO:0008285 228 0.273
spermatid development GO:0007286 4 0.262
cellular protein catabolic process GO:0044257 261 0.259
circulatory system development GO:0072359 262 0.253
centrosome organization GO:0051297 58 0.251
chaperone mediated protein folding requiring cofactor GO:0051085 1 0.246
reproduction GO:0000003 63 0.243
Mouse Worm
g2 m transition of mitotic cell cycle GO:0000086 41 0.241
positive regulation of apoptotic process GO:0043065 246 0.237
regulation of meiotic cell cycle GO:0051445 4 0.234
nuclear division GO:0000280 128 0.231
Fly
negative regulation of protein metabolic process GO:0051248 391 0.230
multicellular organismal reproductive process GO:0048609 40 0.226
negative regulation of mitotic cell cycle GO:0045930 102 0.224
response to nitrogen compound GO:1901698 184 0.219
neurogenesis GO:0022008 169 0.215
chaperone cofactor dependent protein refolding GO:0070389 4 0.214
protein catabolic process GO:0030163 325 0.212
protein polymerization GO:0051258 71 0.205
mitotic sister chromatid separation GO:0051306 18 0.204
developmental process involved in reproduction GO:0003006 66 0.202
Worm
protein dephosphorylation GO:0006470 81 0.201
regulation of mitotic cell cycle GO:0007346 189 0.191
de novo posttranslational protein folding GO:0051084 2 0.191
head development GO:0060322 108 0.189
multicellular organism reproduction GO:0032504 42 0.188
vesicle mediated transport GO:0016192 371 0.187
Worm Fly
cell type specific apoptotic process GO:0097285 125 0.186
Mouse
generation of neurons GO:0048699 152 0.176
regulation of neurogenesis GO:0050767 82 0.174
negative regulation of programmed cell death GO:0043069 321 0.173
regulation of mitosis GO:0007088 63 0.171
single organism reproductive process GO:0044702 98 0.169
Mouse Worm
spermatid differentiation GO:0048515 4 0.160
spindle assembly checkpoint GO:0071173 17 0.156
protein localization to mitochondrion GO:0070585 25 0.156
behavior GO:0007610 112 0.156
cellular component morphogenesis GO:0032989 314 0.155
regulation of cell development GO:0060284 161 0.152
regulation of stem cell proliferation GO:0072091 15 0.149
mitotic cell cycle checkpoint GO:0007093 68 0.148
negative regulation of developmental process GO:0051093 247 0.147
cellular protein complex assembly GO:0043623 188 0.145
regulation of meiosis GO:0040020 3 0.143
regulation of cell cycle process GO:0010564 266 0.136
transmembrane transport GO:0055085 399 0.135
response to organic cyclic compound GO:0014070 204 0.133
negative regulation of cell cycle process GO:0010948 121 0.133
cellular macromolecular complex assembly GO:0034622 324 0.133
negative regulation of apoptotic process GO:0043066 316 0.132
oocyte differentiation GO:0009994 2 0.129
wnt signaling pathway GO:0016055 156 0.127
nervous system development GO:0007399 293 0.127
intracellular protein transport GO:0006886 270 0.125
multi organism reproductive process GO:0044703 54 0.124
Mouse
protein maturation GO:0051604 233 0.124
taxis GO:0042330 157 0.123
embryo development ending in birth or egg hatching GO:0009792 34 0.114
Worm
establishment of protein localization to mitochondrion GO:0072655 22 0.114
negative regulation of cell death GO:0060548 345 0.112
meiotic nuclear division GO:0007126 10 0.107
cell morphogenesis involved in differentiation GO:0000904 144 0.106
aging GO:0007568 66 0.104
locomotory behavior GO:0007626 1 0.103
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.103
protein targeting GO:0006605 187 0.101
response to alkaloid GO:0043279 20 0.099
cellular response to cytokine stimulus GO:0071345 181 0.094
somatic stem cell division GO:0048103 1 0.094
centrosome cycle GO:0007098 32 0.094
cell recognition GO:0008037 9 0.093
Mouse
centriole replication GO:0007099 13 0.091
actin filament based process GO:0030029 224 0.090
dephosphorylation GO:0016311 209 0.089
negative regulation of protein processing GO:0010955 142 0.088
protein targeting to mitochondrion GO:0006626 19 0.086
centrosome duplication GO:0051298 28 0.086
reproductive system development GO:0061458 56 0.083
Worm
sex differentiation GO:0007548 45 0.082
Worm
protein stabilization GO:0050821 64 0.081
regulation of mitotic cell cycle phase transition GO:1901990 118 0.078
negative regulation of cell differentiation GO:0045596 171 0.078
microtubule polymerization or depolymerization GO:0031109 37 0.077
endocytosis GO:0006897 159 0.077
Worm Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.075
oxidation reduction process GO:0055114 396 0.074
sister chromatid segregation GO:0000819 54 0.074
posttranscriptional regulation of gene expression GO:0010608 213 0.073
response to virus GO:0009615 126 0.072
divalent inorganic cation transport GO:0072511 158 0.072
modification dependent macromolecule catabolic process GO:0043632 212 0.072
detection of stimulus GO:0051606 85 0.071
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.070
Fly
cardiovascular system development GO:0072358 262 0.065
oocyte development GO:0048599 1 0.064
response to abiotic stimulus GO:0009628 336 0.064
protein import GO:0017038 130 0.063
cell morphogenesis GO:0000902 296 0.063
regulation of transferase activity GO:0051338 355 0.061
modification dependent protein catabolic process GO:0019941 209 0.061
response to interleukin 1 GO:0070555 47 0.061
regulation of cell division GO:0051302 116 0.060
neuron development GO:0048666 113 0.059
regeneration GO:0031099 4 0.059
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 8 0.058
growth GO:0040007 202 0.058
negative regulation of nervous system development GO:0051961 28 0.058
response to oxygen containing compound GO:1901700 369 0.058
neuron differentiation GO:0030182 138 0.057
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.057
regulation of binding GO:0051098 111 0.057
neuromuscular junction development GO:0007528 3 0.056
anatomical structure formation involved in morphogenesis GO:0048646 284 0.056
response to inorganic substance GO:0010035 127 0.055
regulation of peptidase activity GO:0052547 180 0.054
establishment of protein localization to organelle GO:0072594 172 0.054
regulation of ion transport GO:0043269 189 0.053
membrane organization GO:0061024 292 0.052
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.051
single organism behavior GO:0044708 28 0.051
meiotic cell cycle GO:0051321 13 0.051
response to organonitrogen compound GO:0010243 156 0.050
gamete generation GO:0007276 25 0.050
regulation of cell cycle phase transition GO:1901987 126 0.049
regulation of cellular component biogenesis GO:0044087 281 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.048
negative regulation of phosphate metabolic process GO:0045936 267 0.048
cell projection morphogenesis GO:0048858 129 0.047
sexual reproduction GO:0019953 37 0.045
Mouse
positive regulation of programmed cell death GO:0043068 249 0.045
negative regulation of organelle organization GO:0010639 126 0.045
pattern specification process GO:0007389 43 0.045
regulation of cell migration GO:0030334 289 0.044
lipid metabolic process GO:0006629 381 0.043
chromatin modification GO:0016568 298 0.042
meiotic cell cycle process GO:1903046 8 0.042
negative regulation of binding GO:0051100 57 0.042
mitochondrial membrane organization GO:0007006 40 0.042
mitotic sister chromatid segregation GO:0000070 53 0.041
negative regulation of neuron apoptotic process GO:0043524 23 0.040
meiotic chromosome segregation GO:0045132 4 0.040
regulation of cellular protein catabolic process GO:1903362 96 0.039
positive regulation of developmental process GO:0051094 314 0.039
cytoplasmic transport GO:0016482 379 0.039
regulation of protein kinase activity GO:0045859 289 0.038
protein import into mitochondrial matrix GO:0030150 1 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.038
negative regulation of cell cycle GO:0045786 193 0.038
cellular response to interleukin 1 GO:0071347 35 0.037
regulation of cellular response to stress GO:0080135 244 0.037
cation transport GO:0006812 331 0.037
regulation of cell differentiation GO:0045595 393 0.037
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.037
spermatogenesis GO:0007283 22 0.037
positive regulation of cell death GO:0010942 263 0.037
anterior posterior axis specification GO:0009948 2 0.037
regulation of nervous system development GO:0051960 88 0.036
cell cycle checkpoint GO:0000075 117 0.035
atp metabolic process GO:0046034 176 0.035
adult behavior GO:0030534 18 0.035
behavioral response to nicotine GO:0035095 5 0.034
regulation of protein catabolic process GO:0042176 155 0.034
covalent chromatin modification GO:0016569 254 0.033
regulation of protein localization to nucleus GO:1900180 85 0.033
angiogenesis GO:0001525 147 0.033
energy reserve metabolic process GO:0006112 22 0.033
receptor mediated endocytosis GO:0006898 84 0.033
Worm
nucleotide catabolic process GO:0009166 408 0.032
central nervous system development GO:0007417 123 0.032
segmentation GO:0035282 4 0.032
positive regulation of dna metabolic process GO:0051054 73 0.032
neurological system process GO:0050877 163 0.032
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.031
response to wounding GO:0009611 168 0.031
apoptotic signaling pathway GO:0097190 268 0.031
viral life cycle GO:0019058 132 0.030
negative regulation of protein catabolic process GO:0042177 59 0.030
neuron projection development GO:0031175 106 0.030
response to topologically incorrect protein GO:0035966 29 0.030
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.030
protein localization to membrane GO:0072657 160 0.030
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.028
tissue regeneration GO:0042246 3 0.028
positive regulation of cell cycle GO:0045787 140 0.028
neuron death GO:0070997 65 0.028
protein localization to nucleus GO:0034504 136 0.028
spindle checkpoint GO:0031577 26 0.027
generation of precursor metabolites and energy GO:0006091 68 0.027
chaperone mediated protein complex assembly GO:0051131 9 0.027
actin cytoskeleton organization GO:0030036 207 0.026
positive regulation of proteolysis GO:0045862 142 0.025
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
regulation of translational initiation in response to stress GO:0043558 1 0.025
regulation of dephosphorylation GO:0035303 96 0.025
negative regulation of protein phosphorylation GO:0001933 140 0.025
metal ion transport GO:0030001 272 0.025
dna integrity checkpoint GO:0031570 71 0.025
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.025
trna metabolic process GO:0006399 35 0.025
cytokinesis GO:0000910 96 0.025
regulation of small gtpase mediated signal transduction GO:0051056 156 0.024
positive regulation of peptidase activity GO:0010952 88 0.024
carbohydrate metabolic process GO:0005975 207 0.024
response to temperature stimulus GO:0009266 22 0.024
intracellular protein transmembrane transport GO:0065002 24 0.024
regulation of endopeptidase activity GO:0052548 170 0.023
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
activation of immune response GO:0002253 114 0.023
cellular response to metal ion GO:0071248 43 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.023
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.022
biological phase GO:0044848 5 0.022
ossification GO:0001503 121 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
negative regulation of chromosome organization GO:2001251 48 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
establishment of organelle localization GO:0051656 59 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.020
positive regulation of secretion GO:0051047 116 0.020
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.020
negative regulation of protein modification process GO:0031400 200 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
muscle cell differentiation GO:0042692 63 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
Mouse
apoptotic mitochondrial changes GO:0008637 57 0.018
axonogenesis GO:0007409 31 0.018
negative regulation of proteolysis GO:0045861 132 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
memory GO:0007613 3 0.018
innate immune response GO:0045087 178 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
chordate embryonic development GO:0043009 34 0.018
chromosome separation GO:0051304 23 0.018
cellular carbohydrate metabolic process GO:0044262 84 0.018
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.018
response to light stimulus GO:0009416 87 0.018
interspecies interaction between organisms GO:0044419 156 0.017
Mouse
blastoderm segmentation GO:0007350 2 0.017
establishment of protein localization to membrane GO:0090150 121 0.017
zymogen activation GO:0031638 70 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
response to external biotic stimulus GO:0043207 261 0.017
synaptic transmission GO:0007268 61 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
gonad development GO:0008406 34 0.017
Worm
response to steroid hormone GO:0048545 80 0.017
regulation of membrane potential GO:0042391 95 0.017
brain development GO:0007420 97 0.017
adult locomotory behavior GO:0008344 1 0.017
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
regulation of dna metabolic process GO:0051052 153 0.016
wound healing GO:0042060 115 0.016
positive regulation of mitotic cell cycle GO:0045931 60 0.016
hindbrain development GO:0030902 3 0.016
positive regulation of dna repair GO:0045739 25 0.016
regulation of immune response GO:0050776 201 0.016
cell adhesion GO:0007155 325 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
trachea development GO:0060438 1 0.016
cell fate commitment GO:0045165 27 0.016
epithelial to mesenchymal transition GO:0001837 48 0.016
negative regulation of transferase activity GO:0051348 124 0.015
negative regulation of chromosome segregation GO:0051985 18 0.015
ras protein signal transduction GO:0007265 73 0.015
sensory organ development GO:0007423 52 0.015
calcium ion transport GO:0006816 147 0.015
cell part morphogenesis GO:0032990 137 0.015
response to decreased oxygen levels GO:0036293 96 0.015
cellular amino acid metabolic process GO:0006520 116 0.015
response to lipid GO:0033993 206 0.015
maintenance of location GO:0051235 112 0.015
regulation of kinase activity GO:0043549 314 0.015
mesenchyme development GO:0060485 59 0.015
cellular amine metabolic process GO:0044106 41 0.015
autophagy GO:0006914 88 0.015
negative regulation of growth GO:0045926 97 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
reproductive structure development GO:0048608 55 0.014
Worm
regulation of nuclear division GO:0051783 65 0.014
viral process GO:0016032 146 0.014
cell cycle g2 m phase transition GO:0044839 43 0.014
stem cell differentiation GO:0048863 93 0.014
positive regulation of protein transport GO:0051222 135 0.014
purine containing compound catabolic process GO:0072523 411 0.013
neuron apoptotic process GO:0051402 39 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
regulation of protein binding GO:0043393 66 0.013
positive regulation of catabolic process GO:0009896 310 0.013
regulation of growth GO:0040008 165 0.013
central nervous system neuron development GO:0021954 7 0.013
macromolecule methylation GO:0043414 97 0.012
developmental maturation GO:0021700 28 0.012
response to heat GO:0009408 21 0.012
negative regulation of cell growth GO:0030308 83 0.012
negative regulation of neuron death GO:1901215 32 0.012
cognition GO:0050890 43 0.012
regulation of cell motility GO:2000145 299 0.012
organelle disassembly GO:1903008 9 0.012
response to unfolded protein GO:0006986 24 0.012
positive regulation of protein catabolic process GO:0045732 75 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
positive regulation of cytokine production GO:0001819 167 0.011
regulation of cell cycle g2 m phase transition GO:1902749 22 0.011
germ cell development GO:0007281 8 0.011
cell projection organization GO:0030030 252 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
regulation of response to external stimulus GO:0032101 222 0.011
regulation of protein processing GO:0070613 150 0.011
dna recombination GO:0006310 77 0.011
meiotic cell cycle checkpoint GO:0033313 1 0.011
positive regulation of cell development GO:0010720 92 0.011
cell growth GO:0016049 160 0.011
biological adhesion GO:0022610 331 0.011
endomembrane system organization GO:0010256 196 0.010
developmental growth GO:0048589 48 0.010
negative regulation of dna repair GO:0045738 8 0.010

TCP1 disease predictions

Disease DO term ID Size Probability Func Analog Org