Homo sapiens

234 known processes

TEK

TEK tyrosine kinase, endothelial

(Aliases: TIE2,CD202B,VMCM,TIE-2,VMCM1)

TEK biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
heparin metabolic process GO:0030202 1 1.000
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 1.000
negative regulation of positive chemotaxis GO:0050928 1 1.000
skeletal muscle satellite cell proliferation GO:0014841 1 1.000
tie signaling pathway GO:0048014 3 1.000
positive regulation of blood vessel endothelial cell migration GO:0043536 16 1.000
sprouting angiogenesis GO:0002040 29 1.000
positive regulation of vasoconstriction GO:0045907 3 1.000
regulation of satellite cell proliferation GO:0014842 1 1.000
sulfur compound biosynthetic process GO:0044272 38 1.000
regulation of skeletal muscle cell proliferation GO:0014857 1 1.000
positive regulation of endothelial cell migration GO:0010595 39 1.000
regulation of heterotypic cell cell adhesion GO:0034114 14 1.000
elastic fiber assembly GO:0048251 3 1.000
striated muscle cell proliferation GO:0014855 7 1.000
regulation of receptor internalization GO:0002090 15 0.999
positive regulation of heterotypic cell cell adhesion GO:0034116 8 0.999
positive regulation of receptor internalization GO:0002092 12 0.999
negative regulation of vasculature development GO:1901343 43 0.998
positive regulation of exocytosis GO:0045921 35 0.998
regulation of endothelial cell migration GO:0010594 67 0.998
complement activation lectin pathway GO:0001867 7 0.998
mucopolysaccharide metabolic process GO:1903510 27 0.998
muscle cell proliferation GO:0033002 35 0.998
endothelial cell migration GO:0043542 86 0.996
receptor internalization GO:0031623 43 0.996
cell matrix adhesion GO:0007160 85 0.995
sulfur compound metabolic process GO:0006790 101 0.995
regulation of blood vessel size GO:0050880 18 0.995
positive regulation of epithelial cell migration GO:0010634 55 0.994
regulation of blood circulation GO:1903522 59 0.994
complement activation GO:0006956 19 0.993
regulation of erk1 and erk2 cascade GO:0070372 99 0.993
heterotypic cell cell adhesion GO:0034113 28 0.992
positive regulation of cell motility GO:2000147 177 0.992
negative regulation of epithelial cell migration GO:0010633 38 0.992
regulation of multicellular organismal metabolic process GO:0044246 17 0.991
blood coagulation GO:0007596 76 0.991
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.990
Mouse
regulation of chemotaxis GO:0050920 74 0.990
positive regulation of protein kinase b signaling GO:0051897 42 0.989
regulation of exocytosis GO:0017157 46 0.988
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.988
coagulation GO:0050817 78 0.987
tissue migration GO:0090130 119 0.986
regulation of cellular amine metabolic process GO:0033238 11 0.986
positive regulation of cellular amine metabolic process GO:0033240 7 0.986
skeletal muscle cell proliferation GO:0014856 1 0.985
regulation of collagen metabolic process GO:0010712 15 0.984
negative regulation of blood vessel morphogenesis GO:2000181 41 0.984
negative regulation of angiogenesis GO:0016525 39 0.982
hemostasis GO:0007599 76 0.982
negative regulation of vascular permeability GO:0043116 7 0.981
cellular amino acid metabolic process GO:0006520 116 0.981
response to calcium ion GO:0051592 46 0.981
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.981
multicellular organismal metabolic process GO:0044236 34 0.980
erk1 and erk2 cascade GO:0070371 104 0.980
exocytosis GO:0006887 71 0.979
positive regulation of cell migration GO:0030335 172 0.978
cellular amine metabolic process GO:0044106 41 0.974
endothelial cell apoptotic process GO:0072577 26 0.973
Mouse
regulation of cell cell adhesion GO:0022407 57 0.973
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.972
positive regulation of mapk cascade GO:0043410 190 0.972
blood vessel endothelial cell migration GO:0043534 42 0.972
response to uv b GO:0010224 10 0.971
negative regulation of cell migration GO:0030336 102 0.970
regulation of blood vessel endothelial cell migration GO:0043535 30 0.970
positive regulation of protein transport GO:0051222 135 0.970
Mouse
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.969
epithelium migration GO:0090132 119 0.968
vasoconstriction GO:0042310 11 0.967
multicellular organismal macromolecule metabolic process GO:0044259 29 0.966
single organismal cell cell adhesion GO:0016337 148 0.966
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.963
regulation of body fluid levels GO:0050878 99 0.963
blood vessel development GO:0001568 172 0.963
positive regulation of locomotion GO:0040017 186 0.961
vascular process in circulatory system GO:0003018 29 0.961
single organism cell adhesion GO:0098602 179 0.961
regulation of epithelial cell migration GO:0010632 93 0.960
regulation of cell adhesion GO:0030155 166 0.958
circulatory system process GO:0003013 113 0.957
regulation of tube size GO:0035150 18 0.957
regulation of angiogenesis GO:0045765 92 0.956
angiogenesis GO:0001525 147 0.955
platelet activation GO:0030168 44 0.955
regulation of protein secretion GO:0050708 86 0.953
Mouse
positive regulation of kinase activity GO:0033674 204 0.949
organonitrogen compound biosynthetic process GO:1901566 200 0.949
negative regulation of cellular component movement GO:0051271 106 0.948
regulation of vasculature development GO:1901342 97 0.946
negative regulation of locomotion GO:0040013 118 0.946
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.946
regulation of cellular ketone metabolic process GO:0010565 50 0.945
positive regulation of cell cell adhesion GO:0022409 22 0.945
humoral immune response GO:0006959 49 0.945
regulation of positive chemotaxis GO:0050926 14 0.944
heparin biosynthetic process GO:0030210 1 0.943
signal transduction by phosphorylation GO:0023014 297 0.942
negative regulation of cell adhesion GO:0007162 64 0.942
regulation of cellular amino acid metabolic process GO:0006521 6 0.940
regulation of cell motility GO:2000145 299 0.937
negative regulation of cell motility GO:2000146 104 0.935
cellular response to uv GO:0034644 32 0.934
positive regulation of protein kinase activity GO:0045860 190 0.934
positive regulation of blood circulation GO:1903524 12 0.933
regulation of system process GO:0044057 101 0.932
regulation of vascular permeability GO:0043114 11 0.929
positive regulation of phosphorylation GO:0042327 394 0.928
regulation of cell migration GO:0030334 289 0.928
activation of protein kinase activity GO:0032147 90 0.927
peptidyl tyrosine phosphorylation GO:0018108 170 0.926
platelet aggregation GO:0070527 32 0.925
regulation of hormone levels GO:0010817 125 0.925
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.924
cell substrate adhesion GO:0031589 132 0.923
negative regulation of blood vessel endothelial cell migration GO:0043537 16 0.921
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.921
cell activation GO:0001775 213 0.919
aminoglycan biosynthetic process GO:0006023 29 0.917
positive regulation of secretion by cell GO:1903532 108 0.917
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.917
negative regulation of cell death GO:0060548 345 0.913
Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.911
response to decreased oxygen levels GO:0036293 96 0.910
Rat
positive regulation of cell adhesion GO:0045785 84 0.909
vasculature development GO:0001944 181 0.905
negative regulation of endothelial cell migration GO:0010596 29 0.899
cellular response to decreased oxygen levels GO:0036294 51 0.896
regulation of behavior GO:0050795 82 0.893
regulation of mapk cascade GO:0043408 262 0.891
fibril organization GO:0097435 10 0.890
protein localization to cell surface GO:0034394 28 0.889
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.888
peptide secretion GO:0002790 51 0.886
blood circulation GO:0008015 113 0.886
peptidyl tyrosine modification GO:0018212 170 0.880
ameboidal type cell migration GO:0001667 135 0.877
activation of immune response GO:0002253 114 0.875
epithelial cell migration GO:0010631 119 0.874
amine metabolic process GO:0009308 44 0.874
circulatory system development GO:0072359 262 0.873
regulation of secretion by cell GO:1903530 177 0.872
Mouse
mapk cascade GO:0000165 288 0.868
negative regulation of developmental process GO:0051093 247 0.868
regulation of protein localization GO:0032880 296 0.864
Mouse
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.863
collagen metabolic process GO:0032963 28 0.863
protein modification by small protein conjugation GO:0032446 342 0.862
enzyme linked receptor protein signaling pathway GO:0007167 303 0.862
positive regulation of cellular component organization GO:0051130 376 0.860
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.858
protein kinase b signaling GO:0043491 69 0.855
positive chemotaxis GO:0050918 33 0.852
blood vessel morphogenesis GO:0048514 162 0.845
regulation of protein ubiquitination GO:0031396 95 0.844
immune effector process GO:0002252 159 0.843
Mouse
response to hypoxia GO:0001666 96 0.840
Rat
positive regulation of developmental process GO:0051094 314 0.838
response to metal ion GO:0010038 84 0.837
negative regulation of apoptotic process GO:0043066 316 0.836
Mouse
negative regulation of response to external stimulus GO:0032102 83 0.835
protein ubiquitination GO:0016567 314 0.833
cell adhesion GO:0007155 325 0.831
secretion GO:0046903 254 0.830
Mouse
regulation of vasoconstriction GO:0019229 5 0.830
positive regulation of hormone secretion GO:0046887 25 0.829
anatomical structure formation involved in morphogenesis GO:0048646 284 0.828
signal release GO:0023061 70 0.825
negative regulation of multicellular organismal process GO:0051241 317 0.824
regulation of establishment of protein localization GO:0070201 242 0.820
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 97 0.816
protein polymerization GO:0051258 71 0.815
biological adhesion GO:0022610 331 0.815
cellular response to oxygen levels GO:0071453 55 0.814
cellular ketone metabolic process GO:0042180 80 0.810
peptide transport GO:0015833 74 0.806
glomerulus development GO:0032835 15 0.806
regulation of cellular component movement GO:0051270 334 0.806
peptide hormone secretion GO:0030072 50 0.805
cardiovascular system development GO:0072358 262 0.802
homotypic cell cell adhesion GO:0034109 47 0.801
regulation of endothelial cell apoptotic process GO:2000351 24 0.800
Mouse
cellular protein complex assembly GO:0043623 188 0.800
cellular response to hypoxia GO:0071456 51 0.793
aminoglycan metabolic process GO:0006022 39 0.789
positive regulation of immune system process GO:0002684 283 0.787
Mouse
receptor metabolic process GO:0043112 81 0.785
negative regulation of behavior GO:0048521 15 0.767
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.752
regulation of secretion GO:0051046 194 0.748
Mouse
response to light stimulus GO:0009416 87 0.746
hormone transport GO:0009914 68 0.738
positive regulation of cellular component movement GO:0051272 181 0.735
taxis GO:0042330 157 0.731
regulation of apoptotic signaling pathway GO:2001233 175 0.728
cell cell signaling GO:0007267 155 0.726
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.723
amide transport GO:0042886 76 0.723
apoptotic signaling pathway GO:0097190 268 0.717
system process GO:0003008 349 0.712
negative regulation of programmed cell death GO:0043069 321 0.710
Mouse
chemotaxis GO:0006935 157 0.710
response to inorganic substance GO:0010035 127 0.701
cellular response to radiation GO:0071478 65 0.697
protein secretion GO:0009306 98 0.696
Mouse
regulation of vesicle mediated transport GO:0060627 130 0.694
cellular macromolecular complex assembly GO:0034622 324 0.689
cellular response to abiotic stimulus GO:0071214 117 0.679
positive regulation of protein ubiquitination GO:0031398 53 0.674
response to oxygen levels GO:0070482 100 0.668
Rat
positive regulation of peptide hormone secretion GO:0090277 15 0.662
regulation of transferase activity GO:0051338 355 0.659
wound healing GO:0042060 115 0.647
kidney development GO:0001822 53 0.643
glycosaminoglycan metabolic process GO:0030203 35 0.634
vesicle mediated transport GO:0016192 371 0.634
regulation of anatomical structure morphogenesis GO:0022603 286 0.633
positive regulation of endocytosis GO:0045807 42 0.631
regulation of locomotion GO:0040012 329 0.628
extracellular fibril organization GO:0043206 7 0.610
negative regulation of chemotaxis GO:0050922 13 0.603
positive regulation of peptide secretion GO:0002793 15 0.599
extracellular matrix organization GO:0030198 41 0.597
inositol lipid mediated signaling GO:0048017 55 0.586
extracellular structure organization GO:0043062 41 0.580
nitrogen compound transport GO:0071705 191 0.579
defense response GO:0006952 315 0.572
regulation of peptide secretion GO:0002791 42 0.571
regulation of endocytosis GO:0030100 72 0.558
regulation of peptide transport GO:0090087 62 0.538
protein activation cascade GO:0072376 22 0.537
cellular response to light stimulus GO:0071482 34 0.527
response to lipid GO:0033993 206 0.521
Mouse Rat
response to radiation GO:0009314 151 0.514
response to wounding GO:0009611 168 0.500
cell type specific apoptotic process GO:0097285 125 0.500
Mouse
regulation of response to external stimulus GO:0032101 222 0.492
regeneration GO:0031099 4 0.488
Rat
regulation of protein transport GO:0051223 213 0.488
Mouse
hormone secretion GO:0046879 65 0.484
regulation of anatomical structure size GO:0090066 101 0.477
response to uv GO:0009411 73 0.476
response to abiotic stimulus GO:0009628 336 0.453
Rat
positive regulation of secretion GO:0051047 116 0.445
Mouse
regulation of immune response GO:0050776 201 0.433
Mouse
protein import into nucleus GO:0006606 104 0.430
Mouse
positive regulation of receptor mediated endocytosis GO:0048260 21 0.429
peptidyl serine modification GO:0018209 106 0.424
Mouse
peptidyl serine phosphorylation GO:0018105 101 0.406
Mouse
behavior GO:0007610 112 0.404
glycosaminoglycan biosynthetic process GO:0006024 27 0.398
phosphatidylinositol mediated signaling GO:0048015 55 0.394
regulation of receptor mediated endocytosis GO:0048259 32 0.387
innate immune response GO:0045087 178 0.384
regulation of kinase activity GO:0043549 314 0.383
response to organic cyclic compound GO:0014070 204 0.358
Rat
hemopoiesis GO:0030097 180 0.348
Mouse
single organism nuclear import GO:1902593 104 0.346
Mouse
secretion by cell GO:0032940 226 0.336
Mouse
positive regulation of transferase activity GO:0051347 227 0.333
uv protection GO:0009650 5 0.331
protein targeting GO:0006605 187 0.323
Mouse
negative regulation of cell substrate adhesion GO:0010812 24 0.322
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.319
regulation of hormone secretion GO:0046883 57 0.313
positive regulation of transport GO:0051050 336 0.302
Mouse
kidney vasculature development GO:0061440 7 0.298
positive regulation of angiogenesis GO:0045766 51 0.298
cellular response to uv b GO:0071493 6 0.296
protein oligomerization GO:0051259 173 0.286
immune response GO:0006955 307 0.282
Mouse
endocytosis GO:0006897 159 0.281
regulation of peptidyl serine phosphorylation GO:0033135 50 0.270
Mouse
regulation of adherens junction organization GO:1903391 21 0.268
cell development GO:0048468 328 0.259
single organism cellular localization GO:1902580 332 0.256
Mouse
receptor mediated endocytosis GO:0006898 84 0.250
response to cytokine GO:0034097 232 0.248
cell cell junction organization GO:0045216 69 0.247
protein import GO:0017038 130 0.243
Mouse
regulation of peptide hormone secretion GO:0090276 41 0.238
negative regulation of protein phosphorylation GO:0001933 140 0.232
cytokine production GO:0001816 247 0.231
Mouse
female gonad development GO:0008585 10 0.230
regulation of protein targeting GO:1903533 91 0.229
Mouse
negative regulation of protein secretion GO:0050709 29 0.225
glomerulus vasculature development GO:0072012 6 0.223
regulation of cytokine production involved in immune response GO:0002718 22 0.223
Mouse
positive regulation of focal adhesion assembly GO:0051894 11 0.220
urogenital system development GO:0001655 65 0.219
regulation of cytokine production GO:0001817 232 0.211
Mouse
regulation of intracellular protein transport GO:0033157 123 0.204
Mouse
motor neuron axon guidance GO:0008045 2 0.202
hematopoietic or lymphoid organ development GO:0048534 186 0.202
Mouse
protein localization to organelle GO:0033365 280 0.195
Mouse
response to steroid hormone GO:0048545 80 0.194
Rat
regulation of protein localization to nucleus GO:1900180 85 0.193
Mouse
regulation of protein kinase activity GO:0045859 289 0.185
i kappab kinase nf kappab signaling GO:0007249 166 0.183
ovulation cycle GO:0042698 9 0.180
protein autophosphorylation GO:0046777 123 0.176
cytoplasmic transport GO:0016482 379 0.174
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.173
negative regulation of phosphorus metabolic process GO:0010563 267 0.173
negative regulation of cytokine production GO:0001818 82 0.168
nuclear import GO:0051170 106 0.168
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.164
regulation of cytoplasmic transport GO:1903649 149 0.159
Mouse
response to estrogen GO:0043627 47 0.149
Rat
actin filament based process GO:0030029 224 0.144
cellular response to endogenous stimulus GO:0071495 336 0.144
regulation of immune effector process GO:0002697 91 0.142
Mouse
nucleocytoplasmic transport GO:0006913 176 0.141
Mouse
negative regulation of protein modification process GO:0031400 200 0.141
negative regulation of secretion GO:0051048 58 0.141
negative regulation of protein metabolic process GO:0051248 391 0.140
negative regulation of phosphorylation GO:0042326 174 0.138
nuclear transport GO:0051169 179 0.138
Mouse
lipid metabolic process GO:0006629 381 0.137
cell junction organization GO:0034330 79 0.132
negative regulation of cellular protein metabolic process GO:0032269 353 0.130
focal adhesion assembly GO:0048041 30 0.127
regulation of intracellular transport GO:0032386 195 0.125
Mouse
positive regulation of map kinase activity GO:0043406 80 0.121
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.120
Mouse
ovarian follicle development GO:0001541 5 0.120
cytokine mediated signaling pathway GO:0019221 109 0.117
regulation of protein serine threonine kinase activity GO:0071900 179 0.115
negative regulation of immune system process GO:0002683 136 0.107
protein localization to nucleus GO:0034504 136 0.107
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.105
extracellular matrix assembly GO:0085029 5 0.103
regulation of tumor necrosis factor production GO:0032680 43 0.099
response to growth factor GO:0070848 205 0.093
regulation of protein binding GO:0043393 66 0.092
positive regulation of cellular component biogenesis GO:0044089 158 0.089
cellular lipid metabolic process GO:0044255 303 0.089
negative regulation of secretion by cell GO:1903531 52 0.088
regulation of production of molecular mediator of immune response GO:0002700 25 0.088
Mouse
regulation of neuron apoptotic process GO:0043523 35 0.086
response to nutrient levels GO:0031667 81 0.085
actin cytoskeleton organization GO:0030036 207 0.084
negative regulation of immune response GO:0050777 40 0.081
regulation of protein import into nucleus GO:0042306 78 0.080
Mouse
negative regulation of neuron apoptotic process GO:0043524 23 0.078
nerve development GO:0021675 4 0.078
nucleoside phosphate catabolic process GO:1901292 412 0.077
regulation of lipid metabolic process GO:0019216 96 0.077
development of primary female sexual characteristics GO:0046545 10 0.075
ovulation cycle process GO:0022602 9 0.075
organophosphate catabolic process GO:0046434 430 0.074
regulation of cell differentiation GO:0045595 393 0.073
protein homooligomerization GO:0051260 100 0.072
cell substrate junction assembly GO:0007044 35 0.071
regulation of neuron death GO:1901214 56 0.069
positive regulation of hydrolase activity GO:0051345 331 0.067
negative regulation of production of molecular mediator of immune response GO:0002701 13 0.067
neuron apoptotic process GO:0051402 39 0.067
glycosyl compound catabolic process GO:1901658 413 0.066
ion transmembrane transport GO:0034220 338 0.066
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.065
purine nucleoside triphosphate catabolic process GO:0009146 392 0.065
nephron development GO:0072006 30 0.065
regulation of actin cytoskeleton organization GO:0032956 116 0.063
response to extracellular stimulus GO:0009991 85 0.062
angiogenesis involved in wound healing GO:0060055 4 0.062
tumor necrosis factor production GO:0032640 43 0.061
lung alveolus development GO:0048286 4 0.061
regulation of nucleotide metabolic process GO:0006140 269 0.061
cell projection organization GO:0030030 252 0.060
peripheral nervous system development GO:0007422 2 0.059
leukocyte chemotaxis GO:0030595 76 0.058
small gtpase mediated signal transduction GO:0007264 78 0.056
immune system development GO:0002520 195 0.055
Mouse
response to nutrient GO:0007584 20 0.054
embryo development GO:0009790 123 0.053
dephosphorylation GO:0016311 209 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.051
regulation of cell matrix adhesion GO:0001952 42 0.050
negative regulation of protein localization to nucleus GO:1900181 34 0.050
regulation of map kinase activity GO:0043405 108 0.050
purine ribonucleoside catabolic process GO:0046130 398 0.049
adherens junction organization GO:0034332 36 0.049
negative regulation of intracellular transport GO:0032387 60 0.048
positive regulation of cell matrix adhesion GO:0001954 23 0.048
purine nucleoside triphosphate metabolic process GO:0009144 412 0.046
positive regulation of cell proliferation GO:0008284 301 0.046
reproductive system development GO:0061458 56 0.045
purine nucleoside catabolic process GO:0006152 398 0.045
regulation of cell junction assembly GO:1901888 29 0.045
transmembrane transport GO:0055085 399 0.044
regulation of wound healing GO:0061041 56 0.044
regulation of cell substrate adhesion GO:0010810 68 0.044
negative regulation of blood coagulation GO:0030195 22 0.044
cellular response to nitrogen compound GO:1901699 144 0.044
purine ribonucleotide catabolic process GO:0009154 404 0.043
renal system development GO:0072001 63 0.043
negative regulation of cell proliferation GO:0008285 228 0.042
lipid biosynthetic process GO:0008610 177 0.042
cellular response to hormone stimulus GO:0032870 125 0.041
positive regulation of cell differentiation GO:0045597 211 0.040
negative regulation of immune effector process GO:0002698 38 0.040
reproductive structure development GO:0048608 55 0.040
negative regulation of protein import into nucleus GO:0042308 30 0.040
leukocyte activation GO:0045321 164 0.040
ras protein signal transduction GO:0007265 73 0.040
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.039
extrinsic apoptotic signaling pathway GO:0097191 119 0.038
plasma membrane fusion GO:0045026 2 0.038
response to hormone GO:0009725 175 0.038
Rat
cytokine production involved in immune response GO:0002367 27 0.038
Mouse
regulation of cytoskeleton organization GO:0051493 177 0.037
central nervous system development GO:0007417 123 0.036
cellular divalent inorganic cation homeostasis GO:0072503 128 0.036
myeloid leukocyte migration GO:0097529 62 0.036
carbohydrate metabolic process GO:0005975 207 0.036
substrate adhesion dependent cell spreading GO:0034446 41 0.035
oogenesis GO:0048477 2 0.035
regulation of cell cycle GO:0051726 393 0.035
ossification GO:0001503 121 0.034
Rat
stress activated protein kinase signaling cascade GO:0031098 94 0.034
divalent metal ion transport GO:0070838 152 0.033
cellular response to cytokine stimulus GO:0071345 181 0.033
regulation of endothelial cell proliferation GO:0001936 56 0.033
post embryonic development GO:0009791 2 0.033
tissue morphogenesis GO:0048729 96 0.033
positive regulation of cell substrate adhesion GO:0010811 37 0.033
regulation of dna metabolic process GO:0051052 153 0.033
negative regulation of protein transport GO:0051224 75 0.032
reactive nitrogen species metabolic process GO:2001057 3 0.032
cellular response to oxygen containing compound GO:1901701 276 0.032
cyclic nucleotide metabolic process GO:0009187 82 0.032
reactive oxygen species metabolic process GO:0072593 75 0.032
patterning of blood vessels GO:0001569 2 0.032
single organism reproductive process GO:0044702 98 0.031
epithelium development GO:0060429 227 0.031
guanosine containing compound metabolic process GO:1901068 244 0.031
divalent inorganic cation transport GO:0072511 158 0.031
membrane organization GO:0061024 292 0.031
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
cell chemotaxis GO:0060326 112 0.030
establishment of protein localization to organelle GO:0072594 172 0.030
Mouse
determination of adult lifespan GO:0008340 2 0.030
protein targeting to nucleus GO:0044744 104 0.030
Mouse
divalent inorganic cation homeostasis GO:0072507 136 0.030
female gamete generation GO:0007292 2 0.030
response to vitamin GO:0033273 13 0.030
intracellular protein transport GO:0006886 270 0.029
Mouse
smooth muscle cell proliferation GO:0048659 28 0.029
regulation of cellular component biogenesis GO:0044087 281 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
mitotic cell cycle process GO:1903047 286 0.029
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.029
regulation of smooth muscle cell proliferation GO:0048660 28 0.029
multicellular organismal aging GO:0010259 3 0.029
nervous system development GO:0007399 293 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.028
gtp metabolic process GO:0046039 239 0.028
regulation of endopeptidase activity GO:0052548 170 0.028
epithelial cell differentiation GO:0030855 141 0.028
organic hydroxy compound metabolic process GO:1901615 147 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
memory GO:0007613 3 0.027
lymphocyte activation GO:0046649 133 0.027
segmentation GO:0035282 4 0.026
blood vessel maturation GO:0001955 1 0.026
cell junction assembly GO:0034329 67 0.026
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.026
positive regulation of cell death GO:0010942 263 0.026
cellular response to organic cyclic compound GO:0071407 127 0.026
reactive oxygen species biosynthetic process GO:1903409 4 0.026
positive regulation of epithelial cell proliferation GO:0050679 65 0.026
vasculogenesis GO:0001570 8 0.026
Mouse
single organism membrane organization GO:0044802 268 0.026
negative regulation of cytokine production involved in immune response GO:0002719 13 0.026
protein catabolic process GO:0030163 325 0.025
positive regulation of lipid kinase activity GO:0090218 13 0.025
chordate embryonic development GO:0043009 34 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
regulation of actin filament based process GO:0032970 141 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.025
salivary gland morphogenesis GO:0007435 4 0.025
positive regulation of organelle organization GO:0010638 195 0.025
protein localization to membrane GO:0072657 160 0.025
neuron death GO:0070997 65 0.025
cellular response to dna damage stimulus GO:0006974 379 0.024
cardiac muscle cell contraction GO:0086003 4 0.024

TEK disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.049
disease of cellular proliferation DOID:14566 174 0.049
organ system cancer DOID:0050686 164 0.028