Homo sapiens

75 known processes

TERF2

telomeric repeat binding factor 2

(Aliases: TRF2,TRBF2)

TERF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of telomere maintenance GO:0032205 9 1.000
telomere maintenance GO:0000723 32 1.000
telomere capping GO:0016233 5 1.000
regulation of telomere maintenance GO:0032204 13 1.000
protein localization to chromosome telomeric region GO:0070198 6 0.999
telomere maintenance via telomere lengthening GO:0010833 9 0.998
Human
negative regulation of chromosome organization GO:2001251 48 0.988
telomere organization GO:0032200 33 0.987
negative regulation of telomere maintenance via telomerase GO:0032211 5 0.983
Human
cellular response to dna damage stimulus GO:0006974 379 0.969
negative regulation of dna metabolic process GO:0051053 57 0.966
negative regulation of homeostatic process GO:0032845 59 0.963
anatomical structure homeostasis GO:0060249 100 0.960
protein localization to chromosome GO:0034502 30 0.934
dna recombination GO:0006310 77 0.926
double strand break repair via single strand annealing GO:0045002 4 0.911
positive regulation of telomere maintenance GO:0032206 4 0.908
Mouse
protection from non homologous end joining at telomere GO:0031848 3 0.904
regulation of homeostatic process GO:0032844 121 0.835
regulation of chromosome organization GO:0033044 103 0.834
negative regulation of organelle organization GO:0010639 126 0.801
regulation of dna metabolic process GO:0051052 153 0.792
dna replication GO:0006260 116 0.747
Human
double strand break repair via homologous recombination GO:0000724 50 0.740
nucleotide excision repair dna incision GO:0033683 7 0.714
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.711
regulation of telomere maintenance via telomerase GO:0032210 6 0.626
Human
chromatin modification GO:0016568 298 0.578
Human
negative regulation of glycoprotein metabolic process GO:1903019 8 0.571
regeneration GO:0031099 4 0.537
negative regulation of dna replication GO:0008156 29 0.532
Human
dna conformation change GO:0071103 113 0.515
cell cycle checkpoint GO:0000075 117 0.498
Human
dna biosynthetic process GO:0071897 40 0.497
Human
cellular carbohydrate metabolic process GO:0044262 84 0.465
double strand break repair GO:0006302 101 0.460
positive regulation of dna metabolic process GO:0051054 73 0.436
Mouse
protein localization to organelle GO:0033365 280 0.412
negative regulation of glycoprotein biosynthetic process GO:0010561 5 0.400
chromatin organization GO:0006325 351 0.354
Human
dna double strand break processing GO:0000729 10 0.337
negative regulation of cellular protein metabolic process GO:0032269 353 0.335
Human
negative regulation of cellular component organization GO:0051129 235 0.306
protein glycosylation GO:0006486 62 0.297
segmentation GO:0035282 4 0.296
negative regulation of apoptotic process GO:0043066 316 0.259
rna dependent dna replication GO:0006278 16 0.240
Human
negative regulation of protein metabolic process GO:0051248 391 0.236
Human
recombinational repair GO:0000725 50 0.229
tissue regeneration GO:0042246 3 0.227
macromolecule glycosylation GO:0043413 63 0.224
positive regulation of organelle organization GO:0010638 195 0.202
Human Mouse
cellular response to endogenous stimulus GO:0071495 336 0.195
glycoprotein metabolic process GO:0009100 110 0.181
carbohydrate derivative biosynthetic process GO:1901137 207 0.171
response to biotic stimulus GO:0009607 276 0.161
dna repair GO:0006281 198 0.158
regulation of carbohydrate metabolic process GO:0006109 54 0.148
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.137
negative regulation of epithelial cell proliferation GO:0050680 48 0.134
telomere assembly GO:0032202 5 0.130
non recombinational repair GO:0000726 14 0.127
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.126
Human
ribonucleotide catabolic process GO:0009261 405 0.125
cellular macromolecule catabolic process GO:0044265 380 0.114
Human
intracellular protein transport GO:0006886 270 0.107
dna geometric change GO:0032392 32 0.105
positive regulation of hydrolase activity GO:0051345 331 0.098
purine ribonucleotide catabolic process GO:0009154 404 0.097
mitotic nuclear division GO:0007067 119 0.094
Human
positive regulation of chromosome organization GO:2001252 41 0.093
Mouse
mitotic cell cycle phase transition GO:0044772 162 0.093
Human
g2 m transition of mitotic cell cycle GO:0000086 41 0.091
Human
cellular amino acid metabolic process GO:0006520 116 0.091
nucleoside triphosphate metabolic process GO:0009141 422 0.090
modification dependent protein catabolic process GO:0019941 209 0.090
Human
meiotic chromosome segregation GO:0045132 4 0.089
glycoprotein biosynthetic process GO:0009101 91 0.086
dna catabolic process exonucleolytic GO:0000738 17 0.085
detection of muramyl dipeptide GO:0032498 1 0.085
replicative cell aging GO:0001302 3 0.085
Human
nucleotide excision repair GO:0006289 31 0.083
organelle fission GO:0048285 149 0.081
Human
protein dna complex subunit organization GO:0071824 80 0.080
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.080
dna dependent dna replication GO:0006261 44 0.080
mitochondrion organization GO:0007005 156 0.080
ribonucleoside triphosphate catabolic process GO:0009203 391 0.079
dna duplex unwinding GO:0032508 30 0.076
purine nucleotide catabolic process GO:0006195 405 0.074
negative regulation of carbohydrate metabolic process GO:0045912 20 0.072
negative regulation of proteolysis GO:0045861 132 0.071
Human
response to radiation GO:0009314 151 0.071
regulation of cellular amino acid metabolic process GO:0006521 6 0.070
negative regulation of multicellular organismal process GO:0051241 317 0.068
growth GO:0040007 202 0.068
regulation of proteolysis GO:0030162 293 0.068
Human
regulation of growth rate GO:0040009 1 0.067
nucleotide catabolic process GO:0009166 408 0.067
negative regulation of programmed cell death GO:0043069 321 0.066
protein adp ribosylation GO:0006471 9 0.066
carbohydrate metabolic process GO:0005975 207 0.066
actin filament based process GO:0030029 224 0.064
cell type specific apoptotic process GO:0097285 125 0.064
negative regulation of cell cycle process GO:0010948 121 0.064
Human
nuclear transport GO:0051169 179 0.064
response to wounding GO:0009611 168 0.063
dna synthesis involved in dna repair GO:0000731 6 0.063
positive regulation of dna replication GO:0045740 35 0.062
positive regulation of cellular amine metabolic process GO:0033240 7 0.061
cellular amine metabolic process GO:0044106 41 0.061
protein maturation GO:0051604 233 0.060
Human
response to oxidative stress GO:0006979 121 0.060
protein oligomerization GO:0051259 173 0.059
Human
histone modification GO:0016570 251 0.056
cellular response to abiotic stimulus GO:0071214 117 0.054
negative regulation of developmental process GO:0051093 247 0.054
glycosyl compound catabolic process GO:1901658 413 0.054
hematopoietic or lymphoid organ development GO:0048534 186 0.054
response to oxygen containing compound GO:1901700 369 0.054
regulation of glycoprotein biosynthetic process GO:0010559 14 0.053
reciprocal dna recombination GO:0035825 4 0.053
positive regulation of telomerase activity GO:0051973 4 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.052
epithelial cell proliferation GO:0050673 128 0.051
nucleoside phosphate catabolic process GO:1901292 412 0.051
determination of adult lifespan GO:0008340 2 0.050
post embryonic development GO:0009791 2 0.050
amine metabolic process GO:0009308 44 0.049
single organism cellular localization GO:1902580 332 0.049
cellular ketone metabolic process GO:0042180 80 0.048
dna catabolic process endonucleolytic GO:0000737 37 0.047
reciprocal meiotic recombination GO:0007131 4 0.046
covalent chromatin modification GO:0016569 254 0.046
regulation of growth GO:0040008 165 0.046
regulation of cell division GO:0051302 116 0.046
Human
response to uv GO:0009411 73 0.045
response to ionizing radiation GO:0010212 65 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
single organism carbohydrate metabolic process GO:0044723 193 0.043
cellular response to nitrogen compound GO:1901699 144 0.043
modification dependent macromolecule catabolic process GO:0043632 212 0.043
Human
regulation of protein glycosylation GO:0060049 6 0.041
positive regulation of immune system process GO:0002684 283 0.041
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
multicellular organismal aging GO:0010259 3 0.040
response to external biotic stimulus GO:0043207 261 0.039
chromosome separation GO:0051304 23 0.039
Human
negative regulation of telomerase activity GO:0051974 6 0.039
Human
negative regulation of protein maturation GO:1903318 142 0.038
Human
regulation of cell cycle process GO:0010564 266 0.036
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.036
regulation of binding GO:0051098 111 0.036
protein alkylation GO:0008213 74 0.036
protein dna complex assembly GO:0065004 64 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.035
embryonic appendage morphogenesis GO:0035113 9 0.034
dna packaging GO:0006323 77 0.034
negative regulation of cell proliferation GO:0008285 228 0.034
ribonucleoside catabolic process GO:0042454 406 0.034
rho protein signal transduction GO:0007266 26 0.033
positive regulation of lymphocyte activation GO:0051251 73 0.033
regulation of dna replication GO:0006275 68 0.033
Human
glycosylation GO:0070085 71 0.032
nucleoside monophosphate metabolic process GO:0009123 191 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.032
positive regulation of programmed cell death GO:0043068 249 0.031
Human
oocyte development GO:0048599 1 0.031
anterior posterior axis specification embryo GO:0008595 2 0.031
negative regulation of cell death GO:0060548 345 0.031
secretion GO:0046903 254 0.030
regulation of cell cycle GO:0051726 393 0.030
Human
regulation of protein maturation GO:1903317 150 0.030
Human
oocyte differentiation GO:0009994 2 0.030
purine containing compound catabolic process GO:0072523 411 0.030
response to abiotic stimulus GO:0009628 336 0.030
positive regulation of developmental process GO:0051094 314 0.029
cellular response to radiation GO:0071478 65 0.029
response to lipid GO:0033993 206 0.029
negative regulation of cellular catabolic process GO:0031330 83 0.029
Human
response to organic cyclic compound GO:0014070 204 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
actin cytoskeleton organization GO:0030036 207 0.029
regulation of mitotic cell cycle GO:0007346 189 0.029
Human
limb morphogenesis GO:0035108 16 0.029
cytoplasmic transport GO:0016482 379 0.029
protein import GO:0017038 130 0.029
meiosis i GO:0007127 4 0.028
morphogenesis of embryonic epithelium GO:0016331 4 0.028
mitotic cell cycle process GO:1903047 286 0.028
Human
cellular response to starvation GO:0009267 58 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
regulation of protein catabolic process GO:0042176 155 0.027
Human
cellular response to organic cyclic compound GO:0071407 127 0.027
negative regulation of cellular protein catabolic process GO:1903363 38 0.027
Human
wound healing GO:0042060 115 0.027
purine nucleoside monophosphate metabolic process GO:0009126 186 0.026
protein processing GO:0016485 226 0.026
Human
response to dna integrity checkpoint signaling GO:0072402 4 0.026
telomere maintenance via recombination GO:0000722 4 0.026
cell activation GO:0001775 213 0.026
nucleoside catabolic process GO:0009164 408 0.026
negative regulation of t cell apoptotic process GO:0070233 4 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
nucleoside monophosphate catabolic process GO:0009125 159 0.025
protein catabolic process GO:0030163 325 0.025
Human
dna catabolic process GO:0006308 49 0.025
purine nucleoside monophosphate catabolic process GO:0009128 158 0.025
epidermis morphogenesis GO:0048730 3 0.025
protein import into nucleus GO:0006606 104 0.024
histone methylation GO:0016571 60 0.024
regulation of secretion GO:0051046 194 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
response to cell cycle checkpoint signaling GO:0072396 4 0.024
cell aging GO:0007569 52 0.024
Human
regulation of protein processing GO:0070613 150 0.024
Human
positive regulation of cellular catabolic process GO:0031331 284 0.024
rna processing GO:0006396 255 0.023
regulation of response to dna damage stimulus GO:2001020 94 0.023
response to dna damage checkpoint signaling GO:0072423 4 0.023
regulation of cell differentiation GO:0045595 393 0.023
regulation of response to external stimulus GO:0032101 222 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
positive regulation of apoptotic process GO:0043065 246 0.023
Human
regulation of cytoskeleton organization GO:0051493 177 0.022
Human
regulation of rho protein signal transduction GO:0035023 79 0.022
regulation of helicase activity GO:0051095 8 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
chemical homeostasis GO:0048878 306 0.022
detection of stimulus GO:0051606 85 0.022
immune system development GO:0002520 195 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
Human
cytokine production GO:0001816 247 0.022
sister chromatid segregation GO:0000819 54 0.021
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
negative regulation of catabolic process GO:0009895 104 0.021
Human
cation transmembrane transport GO:0098655 238 0.021
positive regulation of cell death GO:0010942 263 0.021
Human
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
mitotic recombination GO:0006312 8 0.021
g2 dna damage checkpoint GO:0031572 26 0.020
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.020
response to organonitrogen compound GO:0010243 156 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
organophosphate catabolic process GO:0046434 430 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
response to other organism GO:0051707 261 0.020
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.020
regulation of g0 to g1 transition GO:0070316 2 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.020
regulation of protein transport GO:0051223 213 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
positive regulation of transport GO:0051050 336 0.019
reproductive process GO:0022414 106 0.019
atp catabolic process GO:0006200 157 0.019
positive regulation of leukocyte activation GO:0002696 80 0.019
vesicle mediated transport GO:0016192 371 0.019
metal ion transport GO:0030001 272 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
Human
regulation of protein localization GO:0032880 296 0.019
locomotory behavior GO:0007626 1 0.019
methylation GO:0032259 106 0.019
neuroblast proliferation GO:0007405 4 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.018
Human
response to fungus GO:0009620 4 0.018
regulation of cell cycle phase transition GO:1901987 126 0.018
Human
humoral immune response GO:0006959 49 0.018
single organism membrane organization GO:0044802 268 0.018
cellular protein catabolic process GO:0044257 261 0.018
Human
regulation of cytoplasmic transport GO:1903649 149 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
nuclear division GO:0000280 128 0.018
Human
mrna processing GO:0006397 133 0.018
regulation of cellular response to stress GO:0080135 244 0.018
neurotransmitter secretion GO:0007269 4 0.018
protein targeting to nucleus GO:0044744 104 0.018
cellular component morphogenesis GO:0032989 314 0.018
positive regulation of ras gtpase activity GO:0032320 117 0.018
skeletal system development GO:0001501 79 0.018
positive regulation of transferase activity GO:0051347 227 0.018
nuclear import GO:0051170 106 0.018
spindle checkpoint GO:0031577 26 0.017
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
regulation of peptidase activity GO:0052547 180 0.017
regulation of secretion by cell GO:1903530 177 0.017
dna damage response detection of dna damage GO:0042769 3 0.017
positive regulation of catabolic process GO:0009896 310 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.017
atp metabolic process GO:0046034 176 0.017
dephosphorylation GO:0016311 209 0.017
positive regulation of cell activation GO:0050867 81 0.017
regulation of t cell activation GO:0050863 77 0.017
gtp metabolic process GO:0046039 239 0.017
response to hormone GO:0009725 175 0.017
protein localization to membrane GO:0072657 160 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.017
developmental growth GO:0048589 48 0.017
regulation of mitotic sister chromatid separation GO:0010965 27 0.017
Human
blastoderm segmentation GO:0007350 2 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
stem cell differentiation GO:0048863 93 0.017
regulation of smooth muscle cell proliferation GO:0048660 28 0.017
regulation of establishment of protein localization GO:0070201 242 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
internal peptidyl lysine acetylation GO:0018393 97 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
Human
regulation of endopeptidase activity GO:0052548 170 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
signal transduction in response to dna damage GO:0042770 57 0.016
lens development in camera type eye GO:0002088 2 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
telomere maintenance via telomerase GO:0007004 8 0.016
Human
negative regulation of phosphorylation GO:0042326 174 0.016
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.016
positive regulation of dna binding GO:0043388 17 0.016
regulation of dna repair GO:0006282 47 0.016
gene conversion GO:0035822 1 0.016
protein homooligomerization GO:0051260 100 0.016
Human
carboxylic acid biosynthetic process GO:0046394 97 0.016
positive regulation of cytoskeleton organization GO:0051495 83 0.015
Human
reproductive structure development GO:0048608 55 0.015
mitotic spindle assembly checkpoint GO:0007094 14 0.015
Human
regulation of cytokine production GO:0001817 232 0.015
nerve development GO:0021675 4 0.015
negative regulation of protein modification process GO:0031400 200 0.015
somitogenesis GO:0001756 2 0.015
sex determination GO:0007530 3 0.015
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.015
Human
histone h3 k4 methylation GO:0051568 27 0.015
mitotic cell cycle GO:0000278 326 0.015
Human
reactive nitrogen species metabolic process GO:2001057 3 0.015
inner ear morphogenesis GO:0042472 4 0.015
regulation of transferase activity GO:0051338 355 0.015
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
regulation of hormone levels GO:0010817 125 0.015
regulation of lymphocyte activation GO:0051249 103 0.015
regulation of multi organism process GO:0043900 157 0.015
positive regulation of mononuclear cell proliferation GO:0032946 47 0.015
cellular response to ionizing radiation GO:0071479 32 0.015
regulation of gene expression epigenetic GO:0040029 73 0.015
cell growth GO:0016049 160 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
dna integrity checkpoint GO:0031570 71 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
Human
appendage development GO:0048736 23 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
regulation of protein targeting GO:1903533 91 0.014
cellular lipid metabolic process GO:0044255 303 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.014
Human
response to growth factor GO:0070848 205 0.014
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.014
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.014
cell cycle phase transition GO:0044770 173 0.014
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
positive regulation of mitosis GO:0045840 25 0.014
Human
meiotic chromosome separation GO:0051307 3 0.014
gtp catabolic process GO:0006184 237 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
response to nutrient levels GO:0031667 81 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
protein targeting GO:0006605 187 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
Human
replication fork processing GO:0031297 13 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
mitotic dna integrity checkpoint GO:0044774 30 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
response to peptide GO:1901652 65 0.013
regulation of cell development GO:0060284 161 0.013
gonad development GO:0008406 34 0.013
mitotic cell cycle checkpoint GO:0007093 68 0.013
Human
cell substrate adhesion GO:0031589 132 0.013
regulation of cellular component movement GO:0051270 334 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
Human
sensory perception of pain GO:0019233 4 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
response to nitrogen compound GO:1901698 184 0.013
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.013
Human
ribonucleoside monophosphate catabolic process GO:0009158 158 0.013
lipid biosynthetic process GO:0008610 177 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
regulation of neuroblast proliferation GO:1902692 3 0.013
nitrogen compound transport GO:0071705 191 0.013
oxidation reduction process GO:0055114 396 0.013
membrane organization GO:0061024 292 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.013
response to gamma radiation GO:0010332 14 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
small molecule biosynthetic process GO:0044283 157 0.012
base excision repair GO:0006284 21 0.012
adult locomotory behavior GO:0008344 1 0.012
protein deubiquitination GO:0016579 79 0.012
t cell activation GO:0042110 99 0.012
rab protein signal transduction GO:0032482 4 0.012
ameboidal type cell migration GO:0001667 135 0.012
mating GO:0007618 1 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
cardiac muscle contraction GO:0060048 34 0.012
regulation of membrane potential GO:0042391 95 0.012
limb development GO:0060173 23 0.012
sex differentiation GO:0007548 45 0.012
reproductive system development GO:0061458 56 0.012
appendage morphogenesis GO:0035107 16 0.012
positive regulation of secretion GO:0051047 116 0.012
organ formation GO:0048645 3 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
Human
positive regulation of immune response GO:0050778 159 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
negative regulation of transport GO:0051051 176 0.012
neural tube formation GO:0001841 3 0.012
transmembrane transport GO:0055085 399 0.012
peptide metabolic process GO:0006518 51 0.012
sleep GO:0030431 2 0.012
positive regulation of growth GO:0045927 58 0.012
ion transmembrane transport GO:0034220 338 0.012
neuromuscular junction development GO:0007528 3 0.011
regulation of intracellular transport GO:0032386 195 0.011
sequestering of metal ion GO:0051238 24 0.011
positive regulation of cytokine production GO:0001819 167 0.011
tissue migration GO:0090130 119 0.011
negative regulation of defense response GO:0031348 47 0.011
protein acylation GO:0043543 138 0.011
cellular chemical homeostasis GO:0055082 180 0.011
adipose tissue development GO:0060612 2 0.011
response to inorganic substance GO:0010035 127 0.011
secretion by cell GO:0032940 226 0.011
stem cell division GO:0017145 2 0.011
histone h3 acetylation GO:0043966 45 0.011
negative regulation of transferase activity GO:0051348 124 0.011
Human
generation of precursor metabolites and energy GO:0006091 68 0.011
smooth muscle cell proliferation GO:0048659 28 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
positive regulation of intracellular protein transport GO:0090316 76 0.011
innate immune response GO:0045087 178 0.011
tripartite regional subdivision GO:0007351 2 0.011
negative regulation of dna biosynthetic process GO:2000279 11 0.011
Human
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
hindbrain development GO:0030902 3 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
positive regulation of response to dna damage stimulus GO:2001022 43 0.011
regulation of cell adhesion GO:0030155 166 0.011
epithelial cell migration GO:0010631 119 0.011
cation transport GO:0006812 331 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.011
activation of immune response GO:0002253 114 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
regulation of gtpase activity GO:0043087 180 0.011
positive regulation of mhc class i biosynthetic process GO:0045345 4 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
negative regulation of immune system process GO:0002683 136 0.010
response to alkaloid GO:0043279 20 0.010
peptidyl lysine acetylation GO:0018394 101 0.010
regulation of viral process GO:0050792 103 0.010
positive regulation of intracellular transport GO:0032388 104 0.010
cellular amide metabolic process GO:0043603 69 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.010
sequestering of calcium ion GO:0051208 17 0.010

TERF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 26 0.174
immune system disease DOID:2914 155 0.174
aplastic anemia DOID:12449 30 0.174
bone marrow disease DOID:4961 31 0.174
anemia DOID:2355 55 0.174
hematopoietic system disease DOID:74 100 0.174
xeroderma pigmentosum DOID:0050427 8 0.060
musculoskeletal system disease DOID:17 223 0.025
nervous system disease DOID:863 431 0.024
central nervous system disease DOID:331 186 0.024
muscle tissue disease DOID:66 113 0.022
myopathy DOID:423 104 0.022
muscular disease DOID:0080000 114 0.022
neuropathy DOID:870 52 0.020
disease of mental health DOID:150 70 0.018
disease of cellular proliferation DOID:14566 174 0.018
cardiovascular system disease DOID:1287 106 0.016
heart disease DOID:114 68 0.015
disease of metabolism DOID:0014667 295 0.012
cognitive disorder DOID:1561 29 0.011
neurodegenerative disease DOID:1289 102 0.011
acquired metabolic disease DOID:0060158 58 0.011