Homo sapiens

48 known processes

TGM2

transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

(Aliases: TG2,TGC,G-ALPHA-h,GNAH)

TGM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of complement activation lectin pathway GO:0001869 2 0.997
regulation of macrophage chemotaxis GO:0010758 4 0.990
anatomical structure formation involved in morphogenesis GO:0048646 284 0.958
Mouse
secretion by cell GO:0032940 226 0.956
regulation of complement activation lectin pathway GO:0001868 2 0.953
negative regulation of protein activation cascade GO:2000258 7 0.916
regulation of locomotion GO:0040012 329 0.905
g protein coupled receptor signaling pathway GO:0007186 207 0.870
Rat
regulation of cell migration GO:0030334 289 0.861
chemical homeostasis GO:0048878 306 0.855
cellular response to endogenous stimulus GO:0071495 336 0.852
lipid metabolic process GO:0006629 381 0.840
circulatory system development GO:0072359 262 0.831
regulation of cell motility GO:2000145 299 0.817
regulation of peptidase activity GO:0052547 180 0.808
lipid localization GO:0010876 106 0.798
transmembrane transport GO:0055085 399 0.797
lipid biosynthetic process GO:0008610 177 0.795
positive regulation of transport GO:0051050 336 0.759
cation homeostasis GO:0055080 189 0.750
angiogenesis GO:0001525 147 0.742
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.730
cardiovascular system development GO:0072358 262 0.729
glycerolipid biosynthetic process GO:0045017 51 0.725
organic hydroxy compound transport GO:0015850 63 0.725
regulation of leukocyte migration GO:0002685 63 0.717
cyclic nucleotide metabolic process GO:0009187 82 0.689
regulation of cellular ketone metabolic process GO:0010565 50 0.685
regulation of response to external stimulus GO:0032101 222 0.683
Rat
lipid transport GO:0006869 90 0.681
secretion GO:0046903 254 0.681
regulation of proteolysis GO:0030162 293 0.673
ameboidal type cell migration GO:0001667 135 0.672
negative regulation of peptidase activity GO:0010466 91 0.657
negative regulation of protein maturation GO:1903318 142 0.656
positive regulation of locomotion GO:0040017 186 0.653
chemokine production GO:0032602 32 0.652
protein processing GO:0016485 226 0.630
positive regulation of cellular component movement GO:0051272 181 0.627
apoptotic cell clearance GO:0043277 12 0.626
regulation of chemotaxis GO:0050920 74 0.621
regulation of protein maturation GO:1903317 150 0.618
cellular amino acid metabolic process GO:0006520 116 0.610
organic hydroxy compound metabolic process GO:1901615 147 0.608
regulation of cellular component movement GO:0051270 334 0.607
positive regulation of developmental process GO:0051094 314 0.603
negative regulation of endopeptidase activity GO:0010951 84 0.600
cell development GO:0048468 328 0.595
system process GO:0003008 349 0.593
vasculature development GO:0001944 181 0.582
positive regulation of cellular component organization GO:0051130 376 0.580
positive regulation of protein phosphorylation GO:0001934 313 0.579
blood vessel development GO:0001568 172 0.579
ion homeostasis GO:0050801 230 0.568
cellular response to oxygen containing compound GO:1901701 276 0.563
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.545
positive regulation of secretion by cell GO:1903532 108 0.543
positive regulation of fibroblast migration GO:0010763 3 0.541
plasminogen activation GO:0031639 11 0.538
response to organic cyclic compound GO:0014070 204 0.536
negative regulation of complement activation GO:0045916 7 0.532
positive regulation of cytokine production GO:0001819 167 0.515
ion transmembrane transport GO:0034220 338 0.514
positive regulation of acute inflammatory response GO:0002675 2 0.508
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.491
regulation of secretion GO:0051046 194 0.476
cellular response to organic cyclic compound GO:0071407 127 0.472
glial cell migration GO:0008347 4 0.464
cytokine production GO:0001816 247 0.458
positive regulation of g protein coupled receptor protein signaling pathway GO:0045745 9 0.455
regulation of endopeptidase activity GO:0052548 170 0.454
negative regulation of developmental process GO:0051093 247 0.449
positive regulation of lipid storage GO:0010884 10 0.445
acylglycerol biosynthetic process GO:0046463 11 0.442
cellular component morphogenesis GO:0032989 314 0.440
response to oxygen containing compound GO:1901700 369 0.436
regulation of behavior GO:0050795 82 0.430
regulation of system process GO:0044057 101 0.429
receptor metabolic process GO:0043112 81 0.429
regulation of vesicle mediated transport GO:0060627 130 0.426
regulation of leukocyte chemotaxis GO:0002688 46 0.424
triglyceride biosynthetic process GO:0019432 10 0.419
positive regulation of secretion GO:0051047 116 0.419
negative regulation of protein processing GO:0010955 142 0.414
response to growth factor GO:0070848 205 0.408
regulation of ion transmembrane transport GO:0034765 132 0.407
positive regulation of angiogenesis GO:0045766 51 0.396
leukocyte migration GO:0050900 107 0.394
actin filament based process GO:0030029 224 0.390
positive regulation of b cell mediated immunity GO:0002714 4 0.378
response to organonitrogen compound GO:0010243 156 0.377
positive regulation of phosphorylation GO:0042327 394 0.375
positive regulation of endocytosis GO:0045807 42 0.375
positive regulation of cellular amine metabolic process GO:0033240 7 0.374
macrophage chemotaxis GO:0048246 10 0.372
determination of adult lifespan GO:0008340 2 0.372
regulation of angiogenesis GO:0045765 92 0.368
negative regulation of defense response GO:0031348 47 0.363
negative regulation of cell death GO:0060548 345 0.362
blood vessel morphogenesis GO:0048514 162 0.360
negative regulation of programmed cell death GO:0043069 321 0.359
post embryonic development GO:0009791 2 0.358
positive regulation of hydrolase activity GO:0051345 331 0.354
membrane organization GO:0061024 292 0.350
response to nitrogen compound GO:1901698 184 0.347
negative regulation of hydrolase activity GO:0051346 182 0.344
regulation of cytokine production GO:0001817 232 0.342
striated muscle contraction GO:0006941 52 0.341
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.340
negative regulation of proteolysis GO:0045861 132 0.336
response to wounding GO:0009611 168 0.336
Rat
regulation of lipid biosynthetic process GO:0046890 47 0.331
regulation of anatomical structure morphogenesis GO:0022603 286 0.327
positive regulation of cell motility GO:2000147 177 0.324
cellular response to growth factor stimulus GO:0071363 197 0.324
negative regulation of response to external stimulus GO:0032102 83 0.322
cellular homeostasis GO:0019725 196 0.321
single organism membrane organization GO:0044802 268 0.319
regulation of apoptotic cell clearance GO:2000425 5 0.319
negative regulation of cell motility GO:2000146 104 0.318
single organism carbohydrate metabolic process GO:0044723 193 0.313
wound healing GO:0042060 115 0.305
regulation of endocytosis GO:0030100 72 0.301
biological adhesion GO:0022610 331 0.297
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 303 0.297
regulation of cellular response to stress GO:0080135 244 0.297
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.296
negative regulation of cellular component movement GO:0051271 106 0.295
regulation of calcium ion transport GO:0051924 79 0.291
dendritic cell antigen processing and presentation GO:0002468 1 0.284
vesicle mediated transport GO:0016192 371 0.283
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.281
amine metabolic process GO:0009308 44 0.280
regulation of cellular response to growth factor stimulus GO:0090287 76 0.276
regulation of transmembrane transport GO:0034762 139 0.270
endothelial cell migration GO:0043542 86 0.269
complement activation lectin pathway GO:0001867 7 0.267
regulation of triglyceride metabolic process GO:0090207 11 0.267
regulation of protein processing GO:0070613 150 0.265
regulation of lipid storage GO:0010883 21 0.264
apoptotic signaling pathway GO:0097190 268 0.263
negative regulation of behavior GO:0048521 15 0.262
chemotaxis GO:0006935 157 0.261
metal ion transport GO:0030001 272 0.258
cytosolic calcium ion transport GO:0060401 48 0.256
cation transmembrane transport GO:0098655 238 0.254
cell substrate adhesion GO:0031589 132 0.249
response to metal ion GO:0010038 84 0.249
calcium ion transport GO:0006816 147 0.247
regulation of metal ion transport GO:0010959 120 0.246
activation of immune response GO:0002253 114 0.246
regulation of secretion by cell GO:1903530 177 0.244
negative regulation of protein metabolic process GO:0051248 391 0.243
divalent metal ion transport GO:0070838 152 0.242
endochondral bone morphogenesis GO:0060350 3 0.241
regulation of complement activation GO:0030449 8 0.239
defense response GO:0006952 315 0.231
Rat
protein localization to membrane GO:0072657 160 0.229
regulation of establishment of protein localization GO:0070201 242 0.228
negative regulation of locomotion GO:0040013 118 0.223
cellular ketone metabolic process GO:0042180 80 0.223
muscle cell development GO:0055001 29 0.222
regulation of vasculature development GO:1901342 97 0.219
maintenance of location GO:0051235 112 0.218
segmentation GO:0035282 4 0.218
embryonic viscerocranium morphogenesis GO:0048703 1 0.214
nucleoside catabolic process GO:0009164 408 0.214
muscle contraction GO:0006936 73 0.210
positive regulation of programmed cell death GO:0043068 249 0.210
striated muscle cell differentiation GO:0051146 43 0.207
epithelial cell migration GO:0010631 119 0.205
positive regulation of cell differentiation GO:0045597 211 0.200
positive regulation of proteolysis GO:0045862 142 0.200
purine ribonucleotide catabolic process GO:0009154 404 0.200
endocytosis GO:0006897 159 0.199
leukocyte chemotaxis GO:0030595 76 0.199
striated muscle cell development GO:0055002 27 0.197
negative regulation of catalytic activity GO:0043086 335 0.197
cellular divalent inorganic cation homeostasis GO:0072503 128 0.194
regulation of alcohol biosynthetic process GO:1902930 22 0.192
negative regulation of cell migration GO:0030336 102 0.192
negative regulation of apoptotic signaling pathway GO:2001234 97 0.191
cell chemotaxis GO:0060326 112 0.191
epithelium development GO:0060429 227 0.191
Human Mouse
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.191
blood vessel endothelial cell migration GO:0043534 42 0.189
regulation of ion transport GO:0043269 189 0.189
divalent inorganic cation transport GO:0072511 158 0.188
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.188
peptidyl tyrosine modification GO:0018212 170 0.187
taxis GO:0042330 157 0.186
protein maturation GO:0051604 233 0.185
regulation of cellular amino acid metabolic process GO:0006521 6 0.184
neurogenesis GO:0022008 169 0.183
regulation of stress activated mapk cascade GO:0032872 84 0.182
cellular response to cytokine stimulus GO:0071345 181 0.180
regulation of blood coagulation GO:0030193 42 0.178
extracellular matrix organization GO:0030198 41 0.177
inorganic ion transmembrane transport GO:0098660 231 0.177
regulation of purine nucleotide metabolic process GO:1900542 264 0.177
negative regulation of leukocyte migration GO:0002686 14 0.176
cation transport GO:0006812 331 0.174
endosomal transport GO:0016197 129 0.174
regulation of cell development GO:0060284 161 0.173
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.168
regulation of protein activation cascade GO:2000257 8 0.167
positive regulation of nucleotide metabolic process GO:0045981 230 0.166
hematopoietic or lymphoid organ development GO:0048534 186 0.166
cellular lipid metabolic process GO:0044255 303 0.165
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.165
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.164
cellular response to oxidative stress GO:0034599 85 0.164
cell activation GO:0001775 213 0.163
negative regulation of cellular protein metabolic process GO:0032269 353 0.163
regulation of lipid transport GO:0032368 44 0.163
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.162
Rat
muscle cell migration GO:0014812 19 0.160
positive regulation of response to wounding GO:1903036 28 0.160
Rat
regulation of cell activation GO:0050865 125 0.160
protein activation cascade GO:0072376 22 0.157
negative regulation of ion transport GO:0043271 39 0.156
positive regulation of aldosterone metabolic process GO:0032346 2 0.156
response to steroid hormone GO:0048545 80 0.156
interaction with host GO:0051701 42 0.155
hemopoiesis GO:0030097 180 0.151
organic anion transport GO:0015711 103 0.150
organelle assembly GO:0070925 176 0.150
epithelial cell cell adhesion GO:0090136 7 0.149
inorganic cation transmembrane transport GO:0098662 194 0.149
cellular response to biotic stimulus GO:0071216 71 0.148
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.147
positive regulation of gtpase activity GO:0043547 166 0.146
positive regulation of catabolic process GO:0009896 310 0.146
positive regulation of phagocytosis GO:0050766 15 0.146
negative regulation of wound healing GO:0061045 25 0.144
negative regulation of apoptotic process GO:0043066 316 0.143
single organism cellular localization GO:1902580 332 0.143
cell projection organization GO:0030030 252 0.141
endothelial cell cell adhesion GO:0071603 1 0.141
carbohydrate metabolic process GO:0005975 207 0.140
response to lipid GO:0033993 206 0.140
response to other organism GO:0051707 261 0.139
negative regulation of multicellular organismal process GO:0051241 317 0.139
steroid metabolic process GO:0008202 94 0.139
glycerolipid metabolic process GO:0046486 107 0.139
regulation of response to wounding GO:1903034 101 0.138
Rat
positive regulation of protein maturation GO:1903319 6 0.137
chordate embryonic development GO:0043009 34 0.137
protein catabolic process GO:0030163 325 0.137
interspecies interaction between organisms GO:0044419 156 0.137
cell migration involved in gastrulation GO:0042074 1 0.136
regulation of muscle system process GO:0090257 53 0.136
acute inflammatory response GO:0002526 21 0.135
cellular response to nitrogen compound GO:1901699 144 0.135
regulation of protein transport GO:0051223 213 0.135
fibrinolysis GO:0042730 11 0.134
muscle structure development GO:0061061 98 0.134
cellular response to lipopolysaccharide GO:0071222 57 0.133
negative regulation of hemostasis GO:1900047 22 0.133
regulation of apoptotic signaling pathway GO:2001233 175 0.132
negative regulation of nitric oxide mediated signal transduction GO:0010751 2 0.132
immune response GO:0006955 307 0.131
ribonucleoside triphosphate catabolic process GO:0009203 391 0.131
negative regulation of cellular component organization GO:0051129 235 0.131
regulation of lipid metabolic process GO:0019216 96 0.131
regulation of cellular component biogenesis GO:0044087 281 0.131
small molecule biosynthetic process GO:0044283 157 0.130
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.129
nucleoside triphosphate catabolic process GO:0009143 394 0.128
protein secretion GO:0009306 98 0.128
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.128
anterior posterior axis specification GO:0009948 2 0.127
cellular chemical homeostasis GO:0055082 180 0.127
angiogenesis involved in wound healing GO:0060055 4 0.127
negative regulation of blood coagulation GO:0030195 22 0.127
actin cytoskeleton organization GO:0030036 207 0.126
neutral lipid metabolic process GO:0006638 27 0.126
muscle system process GO:0003012 81 0.125
positive regulation of inositol trisphosphate biosynthetic process GO:0032962 1 0.123
response to peptide GO:1901652 65 0.123
positive regulation of kinase activity GO:0033674 204 0.121
negative regulation of cell proliferation GO:0008285 228 0.121
regulation of plasminogen activation GO:0010755 7 0.120
negative regulation of chemotaxis GO:0050922 13 0.120
negative regulation of cell differentiation GO:0045596 171 0.118
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.118
negative regulation of lipid transport GO:0032369 18 0.117
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.117
neuron projection development GO:0031175 106 0.117
response to transforming growth factor beta GO:0071559 94 0.116
regulation of triglyceride biosynthetic process GO:0010866 5 0.115
response to endoplasmic reticulum stress GO:0034976 49 0.115
phagocytosis GO:0006909 42 0.115
regulation of cell differentiation GO:0045595 393 0.115
positive regulation of cell proliferation GO:0008284 301 0.114
Rat
negative regulation of leukocyte chemotaxis GO:0002689 5 0.114
cellular amine metabolic process GO:0044106 41 0.113
circulatory system process GO:0003013 113 0.113
plasma membrane organization GO:0007009 115 0.113
cellular protein catabolic process GO:0044257 261 0.113
purine nucleoside triphosphate metabolic process GO:0009144 412 0.112
integrin mediated signaling pathway GO:0007229 32 0.112
single organismal cell cell adhesion GO:0016337 148 0.112
elastic fiber assembly GO:0048251 3 0.111
negative regulation of binding GO:0051100 57 0.111
regulation of wound healing GO:0061041 56 0.111
osteoblast proliferation GO:0033687 8 0.111
female gamete generation GO:0007292 2 0.110
response to oxygen levels GO:0070482 100 0.110
regulation of nucleotide metabolic process GO:0006140 269 0.109
positive regulation of cellular catabolic process GO:0031331 284 0.109
carboxylic acid transport GO:0046942 63 0.108
glucose transport GO:0015758 30 0.108
steroid biosynthetic process GO:0006694 46 0.108
leukocyte activation GO:0045321 164 0.108
embryo development GO:0009790 123 0.107
mitochondrion organization GO:0007005 156 0.107
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.107
positive regulation of immune system process GO:0002684 283 0.107
regulation of immune response GO:0050776 201 0.107
tissue migration GO:0090130 119 0.103
negative regulation of ion transmembrane transport GO:0034766 26 0.102
acylglycerol metabolic process GO:0006639 27 0.102
nucleotide catabolic process GO:0009166 408 0.102
monosaccharide transport GO:0015749 32 0.102
cell morphogenesis involved in differentiation GO:0000904 144 0.101
skeletal system development GO:0001501 79 0.101
tissue morphogenesis GO:0048729 96 0.101
Mouse
intracellular protein transport GO:0006886 270 0.101
response to carbohydrate GO:0009743 21 0.100
regulation of hormone levels GO:0010817 125 0.099
cell part morphogenesis GO:0032990 137 0.098
response to molecule of bacterial origin GO:0002237 82 0.098
cellular component assembly involved in morphogenesis GO:0010927 73 0.098
nucleoside phosphate catabolic process GO:1901292 412 0.097
hexose transport GO:0008645 30 0.097
positive regulation of protein secretion GO:0050714 60 0.097
neuron development GO:0048666 113 0.097
ribonucleoside catabolic process GO:0042454 406 0.096
cell growth GO:0016049 160 0.095
ribonucleotide catabolic process GO:0009261 405 0.095
oogenesis GO:0048477 2 0.095
negative regulation of response to wounding GO:1903035 47 0.095
oxidation reduction process GO:0055114 396 0.095
response to abiotic stimulus GO:0009628 336 0.095
gtp catabolic process GO:0006184 237 0.094
calcium ion transmembrane transport GO:0070588 76 0.093
regulation of heart contraction GO:0008016 50 0.093
reactive oxygen species metabolic process GO:0072593 75 0.093
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.093
extrinsic apoptotic signaling pathway GO:0097191 119 0.093
positive regulation of protein transport GO:0051222 135 0.093
regulation of immune effector process GO:0002697 91 0.092
positive regulation of nucleotide catabolic process GO:0030813 185 0.092
positive regulation of apoptotic process GO:0043065 246 0.091
single organism reproductive process GO:0044702 98 0.091
epithelium migration GO:0090132 119 0.090
immune effector process GO:0002252 159 0.090
alcohol biosynthetic process GO:0046165 52 0.089
positive regulation of hormone biosynthetic process GO:0046886 4 0.088
nervous system development GO:0007399 293 0.088
complement activation GO:0006956 19 0.088
multicellular organismal aging GO:0010259 3 0.088
cellular response to reactive oxygen species GO:0034614 50 0.088
response to prostaglandin e GO:0034695 6 0.088
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.088
regulation of protein localization GO:0032880 296 0.087
negative regulation of immune system process GO:0002683 136 0.087
lipoprotein metabolic process GO:0042157 42 0.087
purine nucleotide catabolic process GO:0006195 405 0.086
endocrine process GO:0050886 25 0.086
muscle cell differentiation GO:0042692 63 0.086
entry into host GO:0044409 25 0.086
positive regulation of phagocytosis engulfment GO:0060100 1 0.085
response to cytokine GO:0034097 232 0.085
organic acid biosynthetic process GO:0016053 97 0.085
regulation of nucleoside metabolic process GO:0009118 209 0.085
regulation of cell substrate adhesion GO:0010810 68 0.084
positive regulation of cell migration GO:0030335 172 0.084
regulation of cell morphogenesis GO:0022604 153 0.084
regulation of body fluid levels GO:0050878 99 0.084
inflammatory response GO:0006954 79 0.083
Rat
positive regulation of cytoplasmic transport GO:1903651 82 0.083
response to interleukin 1 GO:0070555 47 0.083
erk1 and erk2 cascade GO:0070371 104 0.083
growth GO:0040007 202 0.083
rho protein signal transduction GO:0007266 26 0.083
embryonic placenta development GO:0001892 1 0.082
organophosphate catabolic process GO:0046434 430 0.082
cell morphogenesis GO:0000902 296 0.081
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.081
regulation of glucose transport GO:0010827 23 0.081
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.081
purine ribonucleoside catabolic process GO:0046130 398 0.081
viral life cycle GO:0019058 132 0.080
heart process GO:0003015 62 0.080
regulation of leukocyte mediated immunity GO:0002703 38 0.080
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.080
regulation of protein secretion GO:0050708 86 0.079
positive regulation of mineralocorticoid secretion GO:2000857 1 0.079
establishment of protein localization to organelle GO:0072594 172 0.078
engulfment of apoptotic cell GO:0043652 2 0.078
regulation of chemokine production GO:0032642 31 0.078
cell adhesion GO:0007155 325 0.078
Mouse
positive regulation of immune response GO:0050778 159 0.078
positive regulation of apoptotic cell clearance GO:2000427 5 0.077
regulation of innate immune response GO:0045088 97 0.077
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.077
regulation of receptor biosynthetic process GO:0010869 15 0.076
protein oligomerization GO:0051259 173 0.076
Rat
protein homooligomerization GO:0051260 100 0.076
Rat
nuclear transport GO:0051169 179 0.076
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.076
organic acid transport GO:0015849 65 0.076
response to nitric oxide GO:0071731 4 0.076
positive regulation of cell activation GO:0050867 81 0.075
blood coagulation GO:0007596 76 0.075
kinin cascade GO:0002254 1 0.075
regulation of ion homeostasis GO:2000021 73 0.075
positive regulation of cell death GO:0010942 263 0.074
foam cell differentiation GO:0090077 15 0.074
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.074
regulation of smooth muscle cell migration GO:0014910 15 0.073
lens morphogenesis in camera type eye GO:0002089 2 0.073
somitogenesis GO:0001756 2 0.073
cellular carbohydrate metabolic process GO:0044262 84 0.073
posttranscriptional regulation of gene expression GO:0010608 213 0.073
regulation of macrophage derived foam cell differentiation GO:0010743 14 0.073
divalent inorganic cation homeostasis GO:0072507 136 0.072
neural crest cell migration GO:0001755 2 0.071
behavior GO:0007610 112 0.071
metal ion homeostasis GO:0055065 169 0.071
cellular macromolecule catabolic process GO:0044265 380 0.071
purine nucleoside triphosphate catabolic process GO:0009146 392 0.070
nucleoside triphosphate metabolic process GO:0009141 422 0.070
protein localization to organelle GO:0033365 280 0.070
positive regulation of hemostasis GO:1900048 11 0.070
regeneration GO:0031099 4 0.070
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.069
negative regulation of immune effector process GO:0002698 38 0.069
multi organism cellular process GO:0044764 156 0.069
purine ribonucleoside metabolic process GO:0046128 437 0.069
regulation of carbohydrate metabolic process GO:0006109 54 0.069
positive regulation of mapk cascade GO:0043410 190 0.069
glycosyl compound catabolic process GO:1901658 413 0.069
positive regulation of plasminogen activation GO:0010756 3 0.069
response to lipopolysaccharide GO:0032496 70 0.068
cellular response to interleukin 1 GO:0071347 35 0.068
neuron differentiation GO:0030182 138 0.067
regulation of actin filament based process GO:0032970 141 0.067
regulation of lipoprotein metabolic process GO:0050746 7 0.067
positive regulation of leukocyte migration GO:0002687 46 0.067
signal transduction by phosphorylation GO:0023014 297 0.066
negative regulation of immune response GO:0050777 40 0.066
nucleocytoplasmic transport GO:0006913 176 0.066
response to estrogen GO:0043627 47 0.066
negative regulation of cytokine production GO:0001818 82 0.065
innate immune response GO:0045087 178 0.065
sterol transport GO:0015918 39 0.065
ossification GO:0001503 121 0.064
small gtpase mediated signal transduction GO:0007264 78 0.064
response to external biotic stimulus GO:0043207 261 0.064
neural crest cell development GO:0014032 3 0.064
replacement ossification GO:0036075 1 0.064
negative regulation of transport GO:0051051 176 0.064
response to biotic stimulus GO:0009607 276 0.064
vesicle organization GO:0016050 62 0.063
response to calcium ion GO:0051592 46 0.063
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.063
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.063
cellular response to lipid GO:0071396 127 0.062
regulation of cellular response to oxidative stress GO:1900407 26 0.062
regulation of sequestering of calcium ion GO:0051282 41 0.062
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.062
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.061
positive regulation of cell substrate adhesion GO:0010811 37 0.061
positive regulation of keratinocyte migration GO:0051549 4 0.059
positive regulation of humoral immune response GO:0002922 3 0.059

TGM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
hemolytic anemia DOID:583 20 0.436
hemolytic uremic syndrome DOID:12554 8 0.436
immune system disease DOID:2914 155 0.436
Human
normocytic anemia DOID:720 20 0.436
anemia DOID:2355 55 0.436
hematopoietic system disease DOID:74 100 0.436
Human
retinal disease DOID:5679 118 0.299
retinal degeneration DOID:8466 89 0.299
degeneration of macula and posterior pole DOID:2007 17 0.299
sensory system disease DOID:0050155 203 0.299
macular degeneration DOID:4448 20 0.299
eye and adnexa disease DOID:1492 150 0.299
age related macular degeneration DOID:10871 17 0.299
nervous system disease DOID:863 431 0.299
eye disease DOID:5614 149 0.299
disease of metabolism DOID:0014667 295 0.215
inherited metabolic disorder DOID:655 242 0.095