Homo sapiens

473 known processes

THBS1

thrombospondin 1

(Aliases: TSP-1,TSP1,THBS,TSP,THBS-1)

THBS1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell motility GO:2000147 177 0.994
vasculature development GO:0001944 181 0.992
positive regulation of odontogenesis GO:0042482 3 0.989
tissue morphogenesis GO:0048729 96 0.986
blood vessel morphogenesis GO:0048514 162 0.984
anatomical structure formation involved in morphogenesis GO:0048646 284 0.984
epithelium development GO:0060429 227 0.977
regulation of cell motility GO:2000145 299 0.974
organ morphogenesis GO:0009887 147 0.972
Mouse
regulation of epithelial cell migration GO:0010632 93 0.972
wound healing GO:0042060 115 0.967
tube development GO:0035295 125 0.966
regulation of cell migration GO:0030334 289 0.963
angiogenesis GO:0001525 147 0.956
positive regulation of locomotion GO:0040017 186 0.955
regulation of cellular component movement GO:0051270 334 0.948
circulatory system development GO:0072359 262 0.942
morphogenesis of a branching structure GO:0001763 21 0.941
positive regulation of cellular amine metabolic process GO:0033240 7 0.940
endoderm formation GO:0001706 33 0.939
cell adhesion GO:0007155 325 0.939
positive regulation of epithelial cell migration GO:0010634 55 0.934
positive regulation of fibroblast migration GO:0010763 3 0.928
endothelial cell migration GO:0043542 86 0.922
negative regulation of cellular component movement GO:0051271 106 0.919
positive regulation of programmed cell death GO:0043068 249 0.914
positive regulation of keratinocyte migration GO:0051549 4 0.908
cardiovascular system development GO:0072358 262 0.905
biological adhesion GO:0022610 331 0.903
tube morphogenesis GO:0035239 95 0.903
regulation of keratinocyte migration GO:0051547 4 0.894
regulation of cellular amino acid metabolic process GO:0006521 6 0.892
morphogenesis of an epithelium GO:0002009 60 0.892
single organismal cell cell adhesion GO:0016337 148 0.889
Human
response to wounding GO:0009611 168 0.887
cellular response to endogenous stimulus GO:0071495 336 0.883
enzyme linked receptor protein signaling pathway GO:0007167 303 0.882
ameboidal type cell migration GO:0001667 135 0.881
positive regulation of cellular component movement GO:0051272 181 0.872
circulatory system process GO:0003013 113 0.863
cellular amino acid metabolic process GO:0006520 116 0.862
epithelial cell migration GO:0010631 119 0.857
regulation of cellular amine metabolic process GO:0033238 11 0.855
response to growth factor GO:0070848 205 0.854
positive regulation of protein phosphorylation GO:0001934 313 0.852
positive regulation of cell migration GO:0030335 172 0.849
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.848
multicellular organismal metabolic process GO:0044236 34 0.843
positive regulation of cell death GO:0010942 263 0.842
negative regulation of developmental process GO:0051093 247 0.842
negative regulation of cell migration GO:0030336 102 0.834
response to abiotic stimulus GO:0009628 336 0.830
urogenital system development GO:0001655 65 0.830
negative regulation of cell motility GO:2000146 104 0.828
regulation of locomotion GO:0040012 329 0.826
cell development GO:0048468 328 0.824
blood vessel development GO:0001568 172 0.818
cellular ketone metabolic process GO:0042180 80 0.817
actin cytoskeleton organization GO:0030036 207 0.815
negative regulation of transport GO:0051051 176 0.804
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.801
regulation of cell adhesion GO:0030155 166 0.798
formation of primary germ layer GO:0001704 42 0.798
positive regulation of developmental process GO:0051094 314 0.791
kidney development GO:0001822 53 0.786
response to oxygen containing compound GO:1901700 369 0.785
digestive tract development GO:0048565 75 0.769
positive regulation of apoptotic process GO:0043065 246 0.768
regulation of body fluid levels GO:0050878 99 0.767
amine metabolic process GO:0009308 44 0.758
regulation of cellular ketone metabolic process GO:0010565 50 0.756
gastrulation GO:0007369 51 0.751
epithelium migration GO:0090132 119 0.750
cell substrate adhesion GO:0031589 132 0.749
cell morphogenesis involved in differentiation GO:0000904 144 0.745
positive regulation of cell proliferation GO:0008284 301 0.742
Human
endothelial cell proliferation GO:0001935 65 0.741
positive regulation of cellular component organization GO:0051130 376 0.737
negative regulation of multicellular organismal process GO:0051241 317 0.732
cellular response to organic cyclic compound GO:0071407 127 0.717
cellular component morphogenesis GO:0032989 314 0.701
response to lipid GO:0033993 206 0.681
cellular amine metabolic process GO:0044106 41 0.672
calcium ion homeostasis GO:0055074 122 0.672
taxis GO:0042330 157 0.668
divalent metal ion transport GO:0070838 152 0.667
negative regulation of apoptotic process GO:0043066 316 0.667
regulation of cell differentiation GO:0045595 393 0.667
skin development GO:0043588 76 0.662
muscle cell proliferation GO:0033002 35 0.651
response to organic cyclic compound GO:0014070 204 0.649
renal system development GO:0072001 63 0.646
extracellular matrix organization GO:0030198 41 0.645
regeneration GO:0031099 4 0.640
peptidyl tyrosine phosphorylation GO:0018108 170 0.629
Human
glial cell migration GO:0008347 4 0.628
tissue migration GO:0090130 119 0.627
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.624
Human
regulation of endothelial cell migration GO:0010594 67 0.623
embryonic morphogenesis GO:0048598 85 0.622
negative regulation of locomotion GO:0040013 118 0.619
sprouting angiogenesis GO:0002040 29 0.617
ossification GO:0001503 121 0.615
integrin mediated signaling pathway GO:0007229 32 0.614
regulation of peptidase activity GO:0052547 180 0.613
cellular response to growth factor stimulus GO:0071363 197 0.610
regulation of ion transport GO:0043269 189 0.608
keratinocyte migration GO:0051546 6 0.607
angiogenesis involved in wound healing GO:0060055 4 0.601
regulation of leukocyte migration GO:0002685 63 0.599
Human Mouse
cellular divalent inorganic cation homeostasis GO:0072503 128 0.598
cell matrix adhesion GO:0007160 85 0.595
salivary gland morphogenesis GO:0007435 4 0.590
erk1 and erk2 cascade GO:0070371 104 0.589
negative regulation of hydrogen peroxide metabolic process GO:0010727 3 0.589
post embryonic development GO:0009791 2 0.589
regulation of angiogenesis GO:0045765 92 0.580
response to nitrogen compound GO:1901698 184 0.578
Mouse
system process GO:0003008 349 0.573
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.573
response to estrogen GO:0043627 47 0.564
regulation of cell development GO:0060284 161 0.561
morphogenesis of a branching epithelium GO:0061138 20 0.536
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.536
branching involved in salivary gland morphogenesis GO:0060445 1 0.520
leukocyte migration GO:0050900 107 0.517
Human Mouse
response to organonitrogen compound GO:0010243 156 0.513
lipid metabolic process GO:0006629 381 0.504
branching morphogenesis of an epithelial tube GO:0048754 19 0.498
negative regulation of cell death GO:0060548 345 0.493
skeletal system development GO:0001501 79 0.492
Mouse
response to cytokine GO:0034097 232 0.490
regulation of proteolysis GO:0030162 293 0.487
actin filament based process GO:0030029 224 0.483
cation transport GO:0006812 331 0.480
regulation of protein kinase activity GO:0045859 289 0.480
cellular lipid metabolic process GO:0044255 303 0.479
receptor metabolic process GO:0043112 81 0.475
regulation of cellular component biogenesis GO:0044087 281 0.472
mesenchymal cell development GO:0014031 50 0.467
mapk cascade GO:0000165 288 0.464
cellular ion homeostasis GO:0006873 168 0.464
gland morphogenesis GO:0022612 8 0.461
muscle cell migration GO:0014812 19 0.460
Human
positive regulation of mapk cascade GO:0043410 190 0.460
digestive system development GO:0055123 75 0.458
regulation of endopeptidase activity GO:0052548 170 0.458
carbohydrate metabolic process GO:0005975 207 0.455
response to alcohol GO:0097305 64 0.451
chemotaxis GO:0006935 157 0.448
apoptotic signaling pathway GO:0097190 268 0.447
response to biotic stimulus GO:0009607 276 0.443
cation homeostasis GO:0055080 189 0.442
cellular response to oxygen containing compound GO:1901701 276 0.441
Mouse
kidney epithelium development GO:0072073 25 0.438
cardiac epithelial to mesenchymal transition GO:0060317 3 0.438
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.437
positive regulation of phosphorylation GO:0042327 394 0.434
negative regulation of low density lipoprotein particle receptor biosynthetic process GO:0045715 3 0.433
metal ion homeostasis GO:0055065 169 0.432
reactive oxygen species metabolic process GO:0072593 75 0.430
positive regulation of hydrolase activity GO:0051345 331 0.428
metal ion transport GO:0030001 272 0.427
positive regulation of endothelial cell migration GO:0010595 39 0.420
response to estradiol GO:0032355 23 0.418
regulation of lipoprotein metabolic process GO:0050746 7 0.415
blood circulation GO:0008015 113 0.410
calcium ion transport GO:0006816 147 0.393
negative regulation of cell adhesion GO:0007162 64 0.388
negative regulation of trophoblast cell migration GO:1901164 3 0.388
hematopoietic or lymphoid organ development GO:0048534 186 0.387
response to nutrient GO:0007584 20 0.386
regulation of transferase activity GO:0051338 355 0.386
regulation of actin filament based process GO:0032970 141 0.386
stem cell development GO:0048864 69 0.374
ion homeostasis GO:0050801 230 0.373
negative regulation of cell differentiation GO:0045596 171 0.371
response to mechanical stimulus GO:0009612 51 0.368
positive regulation of organelle organization GO:0010638 195 0.367
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.366
cytokine production GO:0001816 247 0.353
ion transmembrane transport GO:0034220 338 0.352
connective tissue development GO:0061448 39 0.352
Mouse
positive regulation of protein kinase activity GO:0045860 190 0.350
coagulation GO:0050817 78 0.348
response to steroid hormone GO:0048545 80 0.345
epithelial cell differentiation GO:0030855 141 0.335
mucopolysaccharide metabolic process GO:1903510 27 0.334
growth GO:0040007 202 0.331
Mouse
positive regulation of transport GO:0051050 336 0.330
negative regulation of programmed cell death GO:0043069 321 0.329
divalent inorganic cation transport GO:0072511 158 0.328
negative regulation of alkaline phosphatase activity GO:0010693 2 0.327
cardiac muscle tissue development GO:0048738 39 0.324
negative regulation of apoptotic signaling pathway GO:2001234 97 0.324
response to hormone GO:0009725 175 0.311
positive regulation of protein complex assembly GO:0031334 86 0.309
immune system development GO:0002520 195 0.309
positive regulation of immune system process GO:0002684 283 0.308
blood vessel endothelial cell migration GO:0043534 42 0.307
immune response GO:0006955 307 0.303
regulation of mapk cascade GO:0043408 262 0.303
positive regulation of hair follicle maturation GO:0048818 2 0.302
gland development GO:0048732 48 0.297
cell morphogenesis GO:0000902 296 0.296
positive regulation of transferase activity GO:0051347 227 0.296
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.295
Human
regulation of metal ion transport GO:0010959 120 0.295
response to axon injury GO:0048678 1 0.294
vesicle mediated transport GO:0016192 371 0.293
regulation of chemotaxis GO:0050920 74 0.289
regulation of reactive oxygen species metabolic process GO:2000377 41 0.289
peptidyl tyrosine modification GO:0018212 170 0.288
Human
muscle cell development GO:0055001 29 0.287
endodermal cell differentiation GO:0035987 31 0.278
organophosphate biosynthetic process GO:0090407 163 0.277
response to inorganic substance GO:0010035 127 0.273
viral process GO:0016032 146 0.273
cellular response to lipid GO:0071396 127 0.271
cellular calcium ion homeostasis GO:0006874 117 0.271
embryo development GO:0009790 123 0.271
negative regulation of protein metabolic process GO:0051248 391 0.266
cellular homeostasis GO:0019725 196 0.263
cellular metal ion homeostasis GO:0006875 146 0.261
single organism carbohydrate metabolic process GO:0044723 193 0.261
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.257
response to corticosteroid GO:0031960 15 0.257
response to drug GO:0042493 81 0.254
regulation of blood coagulation GO:0030193 42 0.253
positive regulation of kinase activity GO:0033674 204 0.252
chemical homeostasis GO:0048878 306 0.249
heterotypic cell cell adhesion GO:0034113 28 0.248
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.248
positive regulation of cell adhesion GO:0045785 84 0.247
Mouse
epidermis development GO:0008544 59 0.246
nervous system development GO:0007399 293 0.241
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.240
osteoblast differentiation GO:0001649 92 0.240
response to increased oxygen levels GO:0036296 4 0.238
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.234
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.231
multi organism cellular process GO:0044764 156 0.230
regulation of epithelial cell proliferation GO:0050678 113 0.230
regulation of apoptotic signaling pathway GO:2001233 175 0.227
regulation of protein complex assembly GO:0043254 147 0.226
regulation of system process GO:0044057 101 0.226
positive regulation of angiogenesis GO:0045766 51 0.225
regulation of endothelial cell proliferation GO:0001936 56 0.225
regulation of behavior GO:0050795 82 0.223
nucleoside monophosphate metabolic process GO:0009123 191 0.223
cellular chemical homeostasis GO:0055082 180 0.222
positive regulation of mesonephros development GO:0061213 2 0.222
neurogenesis GO:0022008 169 0.220
striated muscle cell differentiation GO:0051146 43 0.219
cyclic nucleotide metabolic process GO:0009187 82 0.218
negative regulation of catalytic activity GO:0043086 335 0.214
extrinsic apoptotic signaling pathway GO:0097191 119 0.214
digestive tract morphogenesis GO:0048546 56 0.214
regulation of smooth muscle cell migration GO:0014910 15 0.211
endoderm development GO:0007492 33 0.211
regulation of response to wounding GO:1903034 101 0.209
positive regulation of peptidase activity GO:0010952 88 0.209
lipid transport GO:0006869 90 0.209
interspecies interaction between organisms GO:0044419 156 0.208
muscle cell differentiation GO:0042692 63 0.208
regulation of carbohydrate metabolic process GO:0006109 54 0.206
nephron development GO:0072006 30 0.206
regulation of leukocyte chemotaxis GO:0002688 46 0.205
Human Mouse
signal transduction by phosphorylation GO:0023014 297 0.205
positive regulation of cellular component biogenesis GO:0044089 158 0.204
mesenchymal cell differentiation GO:0048762 52 0.202
regulation of actin cytoskeleton organization GO:0032956 116 0.202
bone trabecula formation GO:0060346 1 0.200
negative regulation of epithelial cell migration GO:0010633 38 0.199
cell projection organization GO:0030030 252 0.199
regulation of odontogenesis GO:0042481 4 0.199
stress activated protein kinase signaling cascade GO:0031098 94 0.199
cellular response to organonitrogen compound GO:0071417 124 0.197
heart development GO:0007507 95 0.197
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.196
response to fatty acid GO:0070542 13 0.196
regulation of blood pressure GO:0008217 30 0.195
maintenance of location GO:0051235 112 0.195
response to reactive oxygen species GO:0000302 61 0.195
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.194
regulation of cell substrate adhesion GO:0010810 68 0.193
response to oxygen levels GO:0070482 100 0.192
secretion GO:0046903 254 0.192
cartilage development GO:0051216 31 0.192
Mouse
regulation of cardioblast differentiation GO:0051890 4 0.190
morphogenesis of an epithelial sheet GO:0002011 12 0.190
response to hypoxia GO:0001666 96 0.190
muscle structure development GO:0061061 98 0.190
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.190
female gamete generation GO:0007292 2 0.189
cell growth GO:0016049 160 0.188
epithelial cell proliferation GO:0050673 128 0.187
negative regulation of cellular protein metabolic process GO:0032269 353 0.187
response to acid chemical GO:0001101 66 0.186
heart morphogenesis GO:0003007 48 0.186
Mouse
positive regulation of cell differentiation GO:0045597 211 0.185
cellular response to hormone stimulus GO:0032870 125 0.184
negative regulation of phosphate metabolic process GO:0045936 267 0.183
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.181
response to oxidative stress GO:0006979 121 0.181
Mouse
cellular response to cytokine stimulus GO:0071345 181 0.178
vascular wound healing GO:0061042 4 0.177
response to radiation GO:0009314 151 0.175
divalent inorganic cation homeostasis GO:0072507 136 0.175
protein catabolic process GO:0030163 325 0.175
response to decreased oxygen levels GO:0036293 96 0.175
cellular response to molecule of bacterial origin GO:0071219 62 0.174
positive regulation of chemotaxis GO:0050921 57 0.174
positive regulation of osteoblast proliferation GO:0033690 3 0.172
ureteric bud development GO:0001657 13 0.172
organonitrogen compound biosynthetic process GO:1901566 200 0.170
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.169
positive regulation of cell development GO:0010720 92 0.169
regulation of wound healing GO:0061041 56 0.169
response to hyperoxia GO:0055093 4 0.168
generation of neurons GO:0048699 152 0.166
regulation of vesicle mediated transport GO:0060627 130 0.166
hemostasis GO:0007599 76 0.165
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.165
tissue regeneration GO:0042246 3 0.164
negative regulation of phosphorus metabolic process GO:0010563 267 0.164
catagen GO:0042637 3 0.164
negative regulation of hydrolase activity GO:0051346 182 0.164
regulation of transmembrane transport GO:0034762 139 0.163
fibroblast migration GO:0010761 7 0.163
cell activation GO:0001775 213 0.163
transmembrane transport GO:0055085 399 0.162
response to ketone GO:1901654 19 0.161
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.161
regulation of protein binding GO:0043393 66 0.160
phospholipid metabolic process GO:0006644 99 0.160
reproductive process GO:0022414 106 0.159
positive regulation of defense response GO:0031349 87 0.158
response to vitamin GO:0033273 13 0.157
cell migration involved in sprouting angiogenesis GO:0002042 19 0.157
single organism cell adhesion GO:0098602 179 0.154
Human
extracellular structure organization GO:0043062 41 0.152
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.151
regulation of stress activated mapk cascade GO:0032872 84 0.151
regulation of cell cell adhesion GO:0022407 57 0.149
regulation of cell activation GO:0050865 125 0.149
regulation of canonical wnt signaling pathway GO:0060828 88 0.148
response to activity GO:0014823 0 0.145
positive regulation of behavior GO:0048520 60 0.144
regulation of vascular wound healing GO:0061043 2 0.144
interaction with host GO:0051701 42 0.144
positive regulation of stem cell differentiation GO:2000738 29 0.143
regulation of binding GO:0051098 111 0.142
single organism reproductive process GO:0044702 98 0.142
cell adhesion mediated by integrin GO:0033627 27 0.141
Fly
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.140
positive regulation of proteolysis GO:0045862 142 0.138
response to interleukin 1 GO:0070555 47 0.137
plasma membrane organization GO:0007009 115 0.136
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.136
cell junction assembly GO:0034329 67 0.136
regulation of fibroblast migration GO:0010762 7 0.136
platelet activation GO:0030168 44 0.133
regulation of response to external stimulus GO:0032101 222 0.133
protein import GO:0017038 130 0.131
cellular response to external stimulus GO:0071496 111 0.131
tissue remodeling GO:0048771 16 0.131
regulation of smooth muscle cell proliferation GO:0048660 28 0.130
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 22 0.130
cardiocyte differentiation GO:0035051 23 0.130
protein localization to organelle GO:0033365 280 0.129
myeloid cell differentiation GO:0030099 117 0.129
regulation of wnt signaling pathway GO:0030111 123 0.128
regulation of cell morphogenesis GO:0022604 153 0.127
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.127
soft palate development GO:0060023 3 0.127
regulation of secretion GO:0051046 194 0.127
positive regulation of map kinase activity GO:0043406 80 0.126
hematopoietic progenitor cell differentiation GO:0002244 38 0.126
regulation of establishment of protein localization GO:0070201 242 0.125
renal tubule development GO:0061326 19 0.124
secretion by cell GO:0032940 226 0.123
activation of protein kinase activity GO:0032147 90 0.122
inflammatory response GO:0006954 79 0.122
epiboly involved in wound healing GO:0090505 8 0.121
wound healing spreading of cells GO:0044319 8 0.121
cytosolic calcium ion homeostasis GO:0051480 89 0.120
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.120
substrate adhesion dependent cell spreading GO:0034446 41 0.120
negative regulation of cell proliferation GO:0008285 228 0.120
cell migration involved in gastrulation GO:0042074 1 0.119
regulation of nervous system development GO:0051960 88 0.119
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.117
blood coagulation GO:0007596 76 0.116
integrin biosynthetic process GO:0045112 4 0.116
cellular macromolecular complex assembly GO:0034622 324 0.116
regulation of protein transport GO:0051223 213 0.116
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.115
negative regulation of gastrulation GO:2000542 4 0.115
striated muscle contraction GO:0006941 52 0.114
cellular response to interleukin 1 GO:0071347 35 0.113
cellular response to glucocorticoid stimulus GO:0071385 4 0.112
nucleoside triphosphate metabolic process GO:0009141 422 0.110
positive regulation of protein transport GO:0051222 135 0.110
striated muscle cell development GO:0055002 27 0.110
regulation of ossification GO:0030278 58 0.109
regulation of cell cycle GO:0051726 393 0.108
regulation of mesonephros development GO:0061217 3 0.108
negative chemotaxis GO:0050919 11 0.108
actin filament organization GO:0007015 128 0.108
regulation of stem cell differentiation GO:2000736 56 0.108
regulation of cysteine type endopeptidase activity GO:2000116 127 0.108
behavior GO:0007610 112 0.107
sequestering of calcium ion GO:0051208 17 0.107
positive regulation of lymphocyte activation GO:0051251 73 0.107
branch elongation of an epithelium GO:0060602 3 0.107
patterning of blood vessels GO:0001569 2 0.106
positive regulation of phagocytosis engulfment GO:0060100 1 0.106
positive regulation of cytokine production GO:0001819 167 0.106
regulation of nucleotide metabolic process GO:0006140 269 0.106
regulation of neural precursor cell proliferation GO:2000177 4 0.105
stem cell differentiation GO:0048863 93 0.104
single organism membrane organization GO:0044802 268 0.102
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.101
positive regulation of isotype switching to iga isotypes GO:0048298 2 0.100
defense response GO:0006952 315 0.100
cell chemotaxis GO:0060326 112 0.100
retinal ganglion cell axon guidance GO:0031290 2 0.100
mesonephros development GO:0001823 17 0.100
positive regulation of leukocyte chemotaxis GO:0002690 38 0.099
Human Mouse
regulation of kinase activity GO:0043549 314 0.099
cellular component assembly involved in morphogenesis GO:0010927 73 0.099
negative regulation of immune system process GO:0002683 136 0.097
regulation of calcium ion transport GO:0051924 79 0.097
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.097
positive regulation of lipid metabolic process GO:0045834 50 0.096
pathway restricted smad protein phosphorylation GO:0060389 38 0.096
viral life cycle GO:0019058 132 0.096
negative regulation of endopeptidase activity GO:0010951 84 0.096
lipid localization GO:0010876 106 0.095
cellular cation homeostasis GO:0030003 163 0.095
collagen metabolic process GO:0032963 28 0.094
regulation of vasculature development GO:1901342 97 0.094
ribonucleoside monophosphate metabolic process GO:0009161 187 0.093
regulation of cell growth GO:0001558 135 0.093
polysaccharide biosynthetic process GO:0000271 27 0.093
determination of adult lifespan GO:0008340 2 0.092
negative regulation of macrophage cytokine production GO:0010936 3 0.092
smooth muscle cell migration GO:0014909 18 0.091
cell type specific apoptotic process GO:0097285 125 0.090
multicellular organismal aging GO:0010259 3 0.090
endocytosis GO:0006897 159 0.089
protein processing GO:0016485 226 0.089
lipoprotein metabolic process GO:0042157 42 0.088
negative regulation of cell substrate adhesion GO:0010812 24 0.088
axon regeneration GO:0031103 1 0.088
carbohydrate derivative biosynthetic process GO:1901137 207 0.087
positive regulation of stress activated mapk cascade GO:0032874 60 0.087
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.087
response to extracellular stimulus GO:0009991 85 0.087
aminoglycan metabolic process GO:0006022 39 0.086
neuron projection regeneration GO:0031102 1 0.085
regulation of ion homeostasis GO:2000021 73 0.085
neuron differentiation GO:0030182 138 0.085
mesenchyme development GO:0060485 59 0.084
Mouse
movement in host environment GO:0052126 25 0.084
branching involved in ureteric bud morphogenesis GO:0001658 9 0.084
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.083
muscle organ development GO:0007517 56 0.082
Fly
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 1 0.082
trabecula morphogenesis GO:0061383 2 0.082
mononuclear cell proliferation GO:0032943 71 0.082
regulation of glomerulus development GO:0090192 3 0.082
regulation of anatomical structure size GO:0090066 101 0.082
ribonucleotide catabolic process GO:0009261 405 0.082
response to nutrient levels GO:0031667 81 0.082
head development GO:0060322 108 0.081
positive regulation of acute inflammatory response GO:0002675 2 0.081
embryonic viscerocranium morphogenesis GO:0048703 1 0.081
entry into host GO:0044409 25 0.081
platelet aggregation GO:0070527 32 0.081
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.081
collagen fibril organization GO:0030199 10 0.081
entry into host cell GO:0030260 25 0.080
organelle assembly GO:0070925 176 0.080
carbohydrate biosynthetic process GO:0016051 42 0.079

THBS1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.176
blood coagulation disease DOID:1247 21 0.176
hematopoietic system disease DOID:74 100 0.176
musculoskeletal system disease DOID:17 223 0.172
Human
connective tissue disease DOID:65 109 0.172
Human
cancer DOID:162 167 0.121
disease of cellular proliferation DOID:14566 174 0.121
inherited blood coagulation disease DOID:2214 13 0.092
organ system cancer DOID:0050686 164 0.087