Homo sapiens

145 known processes

THOC5

THO complex 5

(Aliases: C22orf19,Fmip,PK1.3,fSAP79)

THOC5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism intracellular transport GO:1902583 14 1.000
transport of virus GO:0046794 14 1.000
intracellular transport of virus GO:0075733 14 1.000
multi organism localization GO:1902579 14 1.000
rna transport GO:0050658 39 1.000
multi organism transport GO:0044766 14 1.000
viral mrna export from host cell nucleus GO:0046784 8 0.999
viral life cycle GO:0019058 132 0.999
mrna transport GO:0051028 30 0.999
multi organism cellular process GO:0044764 156 0.998
nucleic acid transport GO:0050657 39 0.997
viral process GO:0016032 146 0.997
mrna export from nucleus GO:0006406 29 0.995
interspecies interaction between organisms GO:0044419 156 0.992
replication fork processing GO:0031297 13 0.992
nucleobase containing compound transport GO:0015931 51 0.991
rna localization GO:0006403 41 0.990
rna export from nucleus GO:0006405 33 0.986
nitrogen compound transport GO:0071705 191 0.966
cytoplasmic transport GO:0016482 379 0.948
positive regulation of dna templated transcription elongation GO:0032786 18 0.943
nuclear transport GO:0051169 179 0.936
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.915
negative regulation of cell cycle checkpoint GO:1901977 4 0.718
regulation of cell cycle GO:0051726 393 0.717
establishment of rna localization GO:0051236 39 0.692
nuclear export GO:0051168 69 0.645
dna integrity checkpoint GO:0031570 71 0.615
post embryonic development GO:0009791 2 0.602
negative regulation of b cell mediated immunity GO:0002713 3 0.600
nucleocytoplasmic transport GO:0006913 176 0.596
mrna 3 end processing GO:0031124 24 0.589
dna damage checkpoint GO:0000077 68 0.559
female gamete generation GO:0007292 2 0.542
negative regulation of immunoglobulin mediated immune response GO:0002890 3 0.534
regulation of dna damage checkpoint GO:2000001 9 0.525
nucleoside monophosphate catabolic process GO:0009125 159 0.514
regulation of atp metabolic process GO:1903578 29 0.471
cellular response to dna damage stimulus GO:0006974 379 0.429
regulation of atpase activity GO:0043462 25 0.426
regulation of leukocyte mediated immunity GO:0002703 38 0.413
purine nucleoside monophosphate metabolic process GO:0009126 186 0.387
adaptive immune response GO:0002250 49 0.346
glycosyl compound catabolic process GO:1901658 413 0.340
immune response GO:0006955 307 0.299
negative regulation of immune response GO:0050777 40 0.260
organophosphate catabolic process GO:0046434 430 0.257
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.251
negative regulation of cell cycle GO:0045786 193 0.250
purine nucleoside catabolic process GO:0006152 398 0.248
nucleotide excision repair GO:0006289 31 0.243
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.238
response to abiotic stimulus GO:0009628 336 0.232
purine ribonucleoside metabolic process GO:0046128 437 0.228
purine ribonucleoside catabolic process GO:0046130 398 0.199
regulation of response to dna damage stimulus GO:2001020 94 0.199
purine ribonucleotide catabolic process GO:0009154 404 0.196
ribonucleoside monophosphate metabolic process GO:0009161 187 0.191
lymphocyte mediated immunity GO:0002449 48 0.189
nucleoside phosphate catabolic process GO:1901292 412 0.189
dna replication GO:0006260 116 0.188
negative regulation of atpase activity GO:0032780 5 0.187
purine nucleotide catabolic process GO:0006195 405 0.187
oocyte differentiation GO:0009994 2 0.185
immune effector process GO:0002252 159 0.178
ribonucleoside catabolic process GO:0042454 406 0.177
negative regulation of multicellular organismal process GO:0051241 317 0.173
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.171
regulation of atp catabolic process GO:1903289 25 0.162
purine nucleoside monophosphate catabolic process GO:0009128 158 0.161
regulation of immunoglobulin production GO:0002637 4 0.159
purine containing compound catabolic process GO:0072523 411 0.150
regulation of lymphocyte mediated immunity GO:0002706 33 0.146
purine nucleoside triphosphate metabolic process GO:0009144 412 0.141
negative regulation of immune effector process GO:0002698 38 0.137
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.136
regulation of dna recombination GO:0000018 23 0.134
negative regulation of b cell activation GO:0050869 6 0.129
meiotic chromosome segregation GO:0045132 4 0.129
nucleoside catabolic process GO:0009164 408 0.129
regulation of mrna metabolic process GO:1903311 53 0.129
nucleoside triphosphate metabolic process GO:0009141 422 0.123
leukocyte mediated immunity GO:0002443 59 0.123
dna templated transcription elongation GO:0006354 25 0.121
isotype switching GO:0045190 3 0.120
ribonucleoside monophosphate catabolic process GO:0009158 158 0.118
response to heat GO:0009408 21 0.114
transcription coupled nucleotide excision repair GO:0006283 8 0.114
immune system development GO:0002520 195 0.113
ribonucleoside triphosphate catabolic process GO:0009203 391 0.113
regulation of purine nucleotide metabolic process GO:1900542 264 0.112
dna dependent dna replication GO:0006261 44 0.105
negative regulation of phosphate metabolic process GO:0045936 267 0.104
negative regulation of atp metabolic process GO:1903579 7 0.104
regulation of immune effector process GO:0002697 91 0.102
dna recombination GO:0006310 77 0.101
regulation of dna metabolic process GO:0051052 153 0.101
nucleoside monophosphate metabolic process GO:0009123 191 0.099
nucleotide catabolic process GO:0009166 408 0.097
antigen processing and presentation via mhc class ib GO:0002475 3 0.095
regulation of purine nucleotide catabolic process GO:0033121 205 0.091
ribonucleotide catabolic process GO:0009261 405 0.089
regulation of isotype switching GO:0045191 2 0.088
regulation of cellular response to stress GO:0080135 244 0.088
regulation of adaptive immune response GO:0002819 33 0.087
negative regulation of phosphorus metabolic process GO:0010563 267 0.084
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.084
nucleoside triphosphate catabolic process GO:0009143 394 0.082
cell activation GO:0001775 213 0.082
anterior posterior axis specification embryo GO:0008595 2 0.082
atp catabolic process GO:0006200 157 0.080
negative regulation of catalytic activity GO:0043086 335 0.079
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 8 0.079
regulation of helicase activity GO:0051095 8 0.078
chromosome segregation GO:0007059 114 0.077
negative regulation of leukocyte mediated immunity GO:0002704 14 0.077
blastoderm segmentation GO:0007350 2 0.076
negative regulation of lymphocyte mediated immunity GO:0002707 12 0.076
regulation of nucleoside metabolic process GO:0009118 209 0.075
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.075
cell activation involved in immune response GO:0002263 30 0.075
response to cytokine GO:0034097 232 0.074
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.074
regulation of nucleotide catabolic process GO:0030811 205 0.072
regulation of cellular amine metabolic process GO:0033238 11 0.068
protein ubiquitination GO:0016567 314 0.067
negative regulation of immune system process GO:0002683 136 0.067
regulation of isotype switching to iga isotypes GO:0048296 2 0.066
regulation of nucleotide metabolic process GO:0006140 269 0.065
negative regulation of developmental process GO:0051093 247 0.061
segmentation GO:0035282 4 0.061
vitamin d receptor signaling pathway GO:0070561 4 0.060
cell cycle checkpoint GO:0000075 117 0.059
negative regulation of dna recombination GO:0045910 6 0.058
response to temperature stimulus GO:0009266 22 0.058
isotype switching to iga isotypes GO:0048290 2 0.056
lymphocyte activation involved in immune response GO:0002285 20 0.055
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.054
negative regulation of production of molecular mediator of immune response GO:0002701 13 0.052
leukocyte activation involved in immune response GO:0002366 30 0.052
single organism reproductive process GO:0044702 98 0.052
tripartite regional subdivision GO:0007351 2 0.051
regulation of multi organism process GO:0043900 157 0.051
ribonucleoside triphosphate metabolic process GO:0009199 412 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.050
mechanosensory behavior GO:0007638 4 0.049
small molecule biosynthetic process GO:0044283 157 0.049
regulation of cell cycle process GO:0010564 266 0.048
production of molecular mediator of immune response GO:0002440 37 0.048
organonitrogen compound biosynthetic process GO:1901566 200 0.045
oocyte development GO:0048599 1 0.045
atp metabolic process GO:0046034 176 0.045
negative regulation of hydrolase activity GO:0051346 182 0.045
oogenesis GO:0048477 2 0.044
positive regulation of nucleotide metabolic process GO:0045981 230 0.043
membrane organization GO:0061024 292 0.042
cellular amine metabolic process GO:0044106 41 0.042
purine nucleoside triphosphate catabolic process GO:0009146 392 0.040
amine metabolic process GO:0009308 44 0.039
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.039
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.038
negative regulation of response to dna damage stimulus GO:2001021 33 0.038
maturation of ssu rrna GO:0030490 3 0.038
chromatin organization GO:0006325 351 0.037
regulation of b cell mediated immunity GO:0002712 7 0.037
regulation of lymphocyte activation GO:0051249 103 0.037
regulation of cell cycle checkpoint GO:1901976 21 0.037
regulation of leukocyte activation GO:0002694 115 0.036
negative regulation of dna metabolic process GO:0051053 57 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.035
regulation of cell activation GO:0050865 125 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
positive regulation of nucleoside metabolic process GO:0045979 186 0.033
embryo development GO:0009790 123 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
microtubule based process GO:0007017 210 0.031
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.031
regulation of immunoglobulin mediated immune response GO:0002889 7 0.030
defense response GO:0006952 315 0.030
microtubule cytoskeleton organization GO:0000226 176 0.029
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.029
organelle fission GO:0048285 149 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
ossification GO:0001503 121 0.028
leukocyte activation GO:0045321 164 0.027
negative regulation of cellular catabolic process GO:0031330 83 0.027
rna splicing via transesterification reactions GO:0000375 90 0.026
mrna processing GO:0006397 133 0.026
single organism membrane organization GO:0044802 268 0.026
chemical homeostasis GO:0048878 306 0.026
positive regulation of developmental process GO:0051094 314 0.026
b cell activation GO:0042113 33 0.026
regulation of meiosis GO:0040020 3 0.026
spermatid differentiation GO:0048515 4 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
cellular ketone metabolic process GO:0042180 80 0.025
somatic diversification of immune receptors GO:0002200 8 0.025
mrna splicing via spliceosome GO:0000398 89 0.025
lipid localization GO:0010876 106 0.025
lymphocyte activation GO:0046649 133 0.024
regulation of b cell activation GO:0050864 24 0.024
immunoglobulin mediated immune response GO:0016064 10 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
protein localization to membrane GO:0072657 160 0.024
organic acid biosynthetic process GO:0016053 97 0.024
single organism cellular localization GO:1902580 332 0.023
nervous system development GO:0007399 293 0.023
carboxylic acid biosynthetic process GO:0046394 97 0.023
locomotory behavior GO:0007626 1 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
cellular hyperosmotic response GO:0071474 4 0.022
prostate gland development GO:0030850 3 0.022
rna 3 end processing GO:0031123 35 0.022
response to oxygen containing compound GO:1901700 369 0.022
actin filament based process GO:0030029 224 0.022
positive regulation of cell proliferation GO:0008284 301 0.021
chemotaxis GO:0006935 157 0.021
regulation of immune response GO:0050776 201 0.021
oxidation reduction process GO:0055114 396 0.021
endocytosis GO:0006897 159 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 5 0.020
negative regulation of leukocyte activation GO:0002695 26 0.020
cellular response to cytokine stimulus GO:0071345 181 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.019
regulation of viral process GO:0050792 103 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
negative regulation of atp catabolic process GO:1903290 5 0.019
protein localization to plasma membrane GO:0072659 93 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.019
negative regulation of cell proliferation GO:0008285 228 0.018
plasma membrane organization GO:0007009 115 0.018
b cell mediated immunity GO:0019724 10 0.018
reproductive process GO:0022414 106 0.018
regulation of response to external stimulus GO:0032101 222 0.018
anterior posterior axis specification GO:0009948 2 0.018
mitotic cell cycle GO:0000278 326 0.018
lipid metabolic process GO:0006629 381 0.018
positive regulation of immune system process GO:0002684 283 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
anion transport GO:0006820 161 0.017
mitotic cell cycle process GO:1903047 286 0.017
intracellular mrna localization GO:0008298 1 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
somatic diversification of immunoglobulins GO:0016445 6 0.017
protein maturation GO:0051604 233 0.017
myeloid cell differentiation GO:0030099 117 0.017
negative regulation of lymphocyte activation GO:0051250 24 0.016
protein alkylation GO:0008213 74 0.016
regulation of protein localization GO:0032880 296 0.016
negative regulation of cell death GO:0060548 345 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
negative regulation of catabolic process GO:0009895 104 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
cellular lipid metabolic process GO:0044255 303 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
ras protein signal transduction GO:0007265 73 0.016
regulation of vesicle mediated transport GO:0060627 130 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
alpha amino acid biosynthetic process GO:1901607 23 0.015
organic acid transport GO:0015849 65 0.015
lens development in camera type eye GO:0002088 2 0.015
regulation of meiotic cell cycle GO:0051445 4 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
positive regulation of intracellular protein transport GO:0090316 76 0.015
negative regulation of defense response GO:0031348 47 0.015
neurogenesis GO:0022008 169 0.015
regulation of dna templated transcription elongation GO:0032784 23 0.015
endomembrane system organization GO:0010256 196 0.015
negative regulation of purine nucleotide catabolic process GO:0033122 16 0.015
central nervous system development GO:0007417 123 0.015
cellular homeostasis GO:0019725 196 0.015
cytokine mediated signaling pathway GO:0019221 109 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
negative regulation of viral process GO:0048525 66 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
macromolecule methylation GO:0043414 97 0.014
rna interference GO:0016246 4 0.014
regulation of cell development GO:0060284 161 0.014
regulation of production of molecular mediator of immune response GO:0002700 25 0.014
extracellular transport GO:0006858 4 0.014
peptide transport GO:0015833 74 0.014
positive regulation of catabolic process GO:0009896 310 0.014
t cell differentiation in thymus GO:0033077 4 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
regulation of cell division GO:0051302 116 0.014
system process GO:0003008 349 0.014
regulation of mrna splicing via spliceosome GO:0048024 32 0.014
amide transport GO:0042886 76 0.014
mitotic spindle organization GO:0007052 27 0.014
poly a mrna export from nucleus GO:0016973 6 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
response to growth factor GO:0070848 205 0.014
negative regulation of cell activation GO:0050866 33 0.013
cellular chemical homeostasis GO:0055082 180 0.013
rho protein signal transduction GO:0007266 26 0.013
intracellular receptor signaling pathway GO:0030522 104 0.013
reproductive system development GO:0061458 56 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
positive regulation of transport GO:0051050 336 0.013
cell development GO:0048468 328 0.013
embryonic placenta development GO:0001892 1 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
dephosphorylation GO:0016311 209 0.013
translation GO:0006412 132 0.013
nerve development GO:0021675 4 0.013
transmembrane transport GO:0055085 399 0.013
rna secondary structure unwinding GO:0010501 3 0.013
regulation of cell growth GO:0001558 135 0.012
developmental process involved in reproduction GO:0003006 66 0.012
ribosome biogenesis GO:0042254 48 0.012
development of primary sexual characteristics GO:0045137 35 0.012
regulation of cell differentiation GO:0045595 393 0.012
negative regulation of protein processing GO:0010955 142 0.012
positive regulation of ion transport GO:0043270 87 0.012
associative learning GO:0008306 1 0.012
regulation of homeostatic process GO:0032844 121 0.012
lipid transport GO:0006869 90 0.012
cell projection assembly GO:0030031 126 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
regulation of growth GO:0040008 165 0.012
innate immune response GO:0045087 178 0.012
regulation of cell maturation GO:1903429 3 0.012
multicellular organismal aging GO:0010259 3 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
peripheral nervous system development GO:0007422 2 0.011
organic anion transport GO:0015711 103 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
regulation of secretion by cell GO:1903530 177 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
tissue regeneration GO:0042246 3 0.011
organic acid catabolic process GO:0016054 71 0.011
mating GO:0007618 1 0.011
regulation of oocyte development GO:0060281 1 0.011
neuroblast proliferation GO:0007405 4 0.011
negative regulation of protein modification process GO:0031400 200 0.011
regulation of proteolysis GO:0030162 293 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
adult locomotory behavior GO:0008344 1 0.011
endosomal transport GO:0016197 129 0.011
organelle assembly GO:0070925 176 0.011
actin mediated cell contraction GO:0070252 12 0.011
negative regulation of nucleotide catabolic process GO:0030812 16 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
gene silencing GO:0016458 49 0.011
mapk cascade GO:0000165 288 0.011
cilium assembly GO:0042384 63 0.011
actin filament based movement GO:0030048 17 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
positive regulation of cell cycle GO:0045787 140 0.011
cell part morphogenesis GO:0032990 137 0.011
cilium organization GO:0044782 68 0.011
regeneration GO:0031099 4 0.011
negative regulation of proteolysis GO:0045861 132 0.011
chromatin modification GO:0016568 298 0.011
rhythmic behavior GO:0007622 2 0.011
translational initiation GO:0006413 48 0.011
carboxylic acid catabolic process GO:0046395 71 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
motor neuron axon guidance GO:0008045 2 0.011
wnt signaling pathway GO:0016055 156 0.011
small molecule catabolic process GO:0044282 92 0.011
neuromuscular junction development GO:0007528 3 0.011
secretion GO:0046903 254 0.010
positive regulation of protein phosphorylation GO:0001934 313 0.010
response to axon injury GO:0048678 1 0.010
positive regulation of vitamin d receptor signaling pathway GO:0070564 2 0.010
memory GO:0007613 3 0.010
protein dephosphorylation GO:0006470 81 0.010
regulation of intracellular transport GO:0032386 195 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
cation transport GO:0006812 331 0.010
positive regulation of atpase activity GO:0032781 19 0.010
hyperosmotic response GO:0006972 4 0.010
epithelium development GO:0060429 227 0.010
generation of neurons GO:0048699 152 0.010
vesicle mediated transport GO:0016192 371 0.010
regulation of innate immune response GO:0045088 97 0.010

THOC5 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.039
disease of cellular proliferation DOID:14566 174 0.024
primary immunodeficiency disease DOID:612 36 0.017
combined t cell and b cell immunodeficiency DOID:628 12 0.013
retinal disease DOID:5679 118 0.012
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.012
nervous system disease DOID:863 431 0.012
eye disease DOID:5614 149 0.012