Homo sapiens

55 known processes

TLK1

tousled-like kinase 1

(Aliases: KIAA0137,PKU-beta)

TLK1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
female gamete generation GO:0007292 2 0.551
protein catabolic process GO:0030163 325 0.531
Human
oogenesis GO:0048477 2 0.521
chromatin assembly or disassembly GO:0006333 78 0.512
protein ubiquitination GO:0016567 314 0.442
amine metabolic process GO:0009308 44 0.425
cellular amine metabolic process GO:0044106 41 0.418
cellular macromolecular complex assembly GO:0034622 324 0.399
dna replication dependent nucleosome assembly GO:0006335 32 0.367
cellular amino acid metabolic process GO:0006520 116 0.341
cellular component morphogenesis GO:0032989 314 0.338
Fly
positive regulation of cellular component organization GO:0051130 376 0.273
protein modification by small protein conjugation GO:0032446 342 0.271
cell development GO:0048468 328 0.268
histone exchange GO:0043486 3 0.242
positive regulation of cellular amine metabolic process GO:0033240 7 0.233
regulation of cellular amine metabolic process GO:0033238 11 0.227
post embryonic development GO:0009791 2 0.219
regulation of cellular amino acid metabolic process GO:0006521 6 0.204
chromatin assembly GO:0031497 61 0.203
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.199
histone ubiquitination GO:0016574 31 0.197
dna replication independent nucleosome assembly GO:0006336 27 0.192
cellular macromolecule catabolic process GO:0044265 380 0.190
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.187
cellular protein catabolic process GO:0044257 261 0.176
Human
cell morphogenesis GO:0000902 296 0.171
Fly
protein complex disassembly GO:0043241 52 0.168
positive regulation of organelle organization GO:0010638 195 0.158
nucleosome assembly GO:0006334 50 0.156
modification dependent macromolecule catabolic process GO:0043632 212 0.154
Human
cellular ketone metabolic process GO:0042180 80 0.148
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.146
Human
protein acylation GO:0043543 138 0.143
positive regulation of phosphorylation GO:0042327 394 0.137
Worm
cell projection organization GO:0030030 252 0.133
covalent chromatin modification GO:0016569 254 0.132
Fly
dna replication GO:0006260 116 0.131
dna replication dependent nucleosome organization GO:0034723 32 0.127
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.124
Human
cellular component disassembly GO:0022411 92 0.124
modification dependent protein catabolic process GO:0019941 209 0.122
Human
dna replication independent nucleosome organization GO:0034724 27 0.119
regulation of chromatin organization GO:1902275 56 0.117
chromatin modification GO:0016568 298 0.115
Fly
positive regulation of transferase activity GO:0051347 227 0.113
Worm
nucleosome organization GO:0034728 66 0.110
rna processing GO:0006396 255 0.105
cell adhesion GO:0007155 325 0.103
Fly
macromolecular complex disassembly GO:0032984 60 0.095
dna repair GO:0006281 198 0.092
chromatin organization GO:0006325 351 0.091
rna splicing GO:0008380 131 0.088
protein dna complex disassembly GO:0032986 12 0.085
dna conformation change GO:0071103 113 0.085
behavior GO:0007610 112 0.083
mitotic cell cycle GO:0000278 326 0.083
Fly
dna templated transcription elongation GO:0006354 25 0.082
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.079
neuromuscular junction development GO:0007528 3 0.078
cell morphogenesis involved in differentiation GO:0000904 144 0.078
histone acetylation GO:0016573 93 0.076
cellular homeostasis GO:0019725 196 0.075
mitotic cell cycle process GO:1903047 286 0.075
regulation of anatomical structure morphogenesis GO:0022603 286 0.074
Fly
positive regulation of dna templated transcription elongation GO:0032786 18 0.071
peptidyl lysine acetylation GO:0018394 101 0.071
dna packaging GO:0006323 77 0.071
cell projection morphogenesis GO:0048858 129 0.071
vesicle mediated transport GO:0016192 371 0.071
internal protein amino acid acetylation GO:0006475 101 0.069
nervous system development GO:0007399 293 0.065
regulation of transferase activity GO:0051338 355 0.065
Worm
neuron differentiation GO:0030182 138 0.062
cellular protein complex assembly GO:0043623 188 0.059
chemical homeostasis GO:0048878 306 0.059
mrna metabolic process GO:0016071 175 0.057
reproductive process GO:0022414 106 0.057
growth GO:0040007 202 0.055
Worm
protein autophosphorylation GO:0046777 123 0.054
Worm Fly
regulation of cellular component biogenesis GO:0044087 281 0.054
generation of neurons GO:0048699 152 0.054
regulation of cell differentiation GO:0045595 393 0.054
positive regulation of protein kinase activity GO:0045860 190 0.053
Worm
ubiquitin dependent protein catabolic process GO:0006511 206 0.053
Human
protein dna complex assembly GO:0065004 64 0.053
regulation of rna splicing GO:0043484 62 0.052
protein processing GO:0016485 226 0.052
Human
single organism cellular localization GO:1902580 332 0.051
intracellular protein transport GO:0006886 270 0.050
positive regulation of kinase activity GO:0033674 204 0.049
Worm
regulation of protein kinase activity GO:0045859 289 0.049
Worm
chromosome segregation GO:0007059 114 0.048
Human Fly
internal peptidyl lysine acetylation GO:0018393 97 0.048
protein acetylation GO:0006473 116 0.047
immune response GO:0006955 307 0.047
Fly
multicellular organismal aging GO:0010259 3 0.047
mitotic nuclear division GO:0007067 119 0.047
neuron projection development GO:0031175 106 0.046
regulation of cellular response to stress GO:0080135 244 0.045
ras protein signal transduction GO:0007265 73 0.045
regulation of dna templated transcription elongation GO:0032784 23 0.044
regulation of proteolysis GO:0030162 293 0.043
Human
negative regulation of cellular component organization GO:0051129 235 0.043
atp dependent chromatin remodeling GO:0043044 25 0.043
cell cell signaling GO:0007267 155 0.043
regulation of cell cycle GO:0051726 393 0.043
Fly
peptidyl serine phosphorylation GO:0018105 101 0.042
Human
histone modification GO:0016570 251 0.042
Fly
cellular response to dna damage stimulus GO:0006974 379 0.042
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
small gtpase mediated signal transduction GO:0007264 78 0.041
system process GO:0003008 349 0.041
positive regulation of chromosome organization GO:2001252 41 0.041
protein dna complex subunit organization GO:0071824 80 0.040
cell part morphogenesis GO:0032990 137 0.040
positive regulation of developmental process GO:0051094 314 0.040
Worm
ribonucleoside monophosphate catabolic process GO:0009158 158 0.040
positive regulation of protein phosphorylation GO:0001934 313 0.039
Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.039
Human
cellular response to abiotic stimulus GO:0071214 117 0.039
Human
determination of adult lifespan GO:0008340 2 0.039
peptidyl lysine modification GO:0018205 144 0.039
meiotic chromosome segregation GO:0045132 4 0.039
regulation of homeostatic process GO:0032844 121 0.038
regulation of proteasomal protein catabolic process GO:0061136 87 0.038
Human
neurogenesis GO:0022008 169 0.037
biological adhesion GO:0022610 331 0.037
Fly
segmentation GO:0035282 4 0.037
protein maturation GO:0051604 233 0.037
Human
single organism reproductive process GO:0044702 98 0.037
muscle structure development GO:0061061 98 0.037
neuron development GO:0048666 113 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
Human
mrna splicing via spliceosome GO:0000398 89 0.036
atp metabolic process GO:0046034 176 0.036
oocyte development GO:0048599 1 0.036
regulation of locomotion GO:0040012 329 0.036
regulation of growth GO:0040008 165 0.036
Worm
organelle fission GO:0048285 149 0.036
regulation of mitotic cell cycle GO:0007346 189 0.035
positive regulation of chromatin modification GO:1903310 30 0.035
endomembrane system organization GO:0010256 196 0.035
embryo development GO:0009790 123 0.035
Worm Fly
cytoplasmic transport GO:0016482 379 0.035
memory GO:0007613 3 0.035
rna splicing via transesterification reactions GO:0000375 90 0.034
single organism membrane organization GO:0044802 268 0.034
mrna processing GO:0006397 133 0.034
regulation of peptidyl lysine acetylation GO:2000756 22 0.034
histone h2b ubiquitination GO:0033523 8 0.033
regulation of mapk cascade GO:0043408 262 0.033
nucleoside monophosphate metabolic process GO:0009123 191 0.033
atp catabolic process GO:0006200 157 0.033
response to abiotic stimulus GO:0009628 336 0.032
Human
proteasomal protein catabolic process GO:0010498 176 0.032
Human
chromatin disassembly GO:0031498 13 0.032
membrane organization GO:0061024 292 0.032
embryonic epithelial tube formation GO:0001838 4 0.031
positive regulation of transport GO:0051050 336 0.031
response to other organism GO:0051707 261 0.031
Fly
regulation of cell cycle process GO:0010564 266 0.031
morphogenesis of embryonic epithelium GO:0016331 4 0.031
purine ribonucleotide catabolic process GO:0009154 404 0.031
protein polyubiquitination GO:0000209 110 0.030
response to radiation GO:0009314 151 0.030
Human
muscle organ development GO:0007517 56 0.030
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.030
Human
reproduction GO:0000003 63 0.030
Worm
ribonucleotide catabolic process GO:0009261 405 0.030
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.030
regulation of mrna metabolic process GO:1903311 53 0.029
regulation of histone modification GO:0031056 47 0.029
male meiosis GO:0007140 1 0.029
mapk cascade GO:0000165 288 0.029
negative regulation of apoptotic process GO:0043066 316 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
regulation of histone acetylation GO:0035065 19 0.028
oocyte differentiation GO:0009994 2 0.028
macromolecule methylation GO:0043414 97 0.028
Worm
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.028
methylation GO:0032259 106 0.027
Worm
mitotic sister chromatid segregation GO:0000070 53 0.027
locomotory behavior GO:0007626 1 0.027
ribonucleoside monophosphate metabolic process GO:0009161 187 0.027
negative regulation of programmed cell death GO:0043069 321 0.027
protein polymerization GO:0051258 71 0.027
regulation of protein processing GO:0070613 150 0.027
Human
dendrite development GO:0016358 24 0.027
tube development GO:0035295 125 0.027
regulation of cytoskeleton organization GO:0051493 177 0.027
cell growth GO:0016049 160 0.027
positive regulation of cell cycle GO:0045787 140 0.027
regulation of notch signaling pathway GO:0008593 18 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.026
reactive oxygen species metabolic process GO:0072593 75 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
negative regulation of proteolysis GO:0045861 132 0.026
Human
purine nucleotide catabolic process GO:0006195 405 0.025
purine containing compound catabolic process GO:0072523 411 0.025
positive regulation of cell differentiation GO:0045597 211 0.025
regulation of protein catabolic process GO:0042176 155 0.025
Human
positive regulation of histone modification GO:0031058 29 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
actin filament based process GO:0030029 224 0.025
regulation of chromatin modification GO:1903308 51 0.025
neural tube formation GO:0001841 3 0.024
cell cycle phase transition GO:0044770 173 0.024
regulation of dna templated transcription in response to stress GO:0043620 18 0.024
nucleoside monophosphate catabolic process GO:0009125 159 0.024
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.024
secretion GO:0046903 254 0.024
negative regulation of transport GO:0051051 176 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
peptidyl serine modification GO:0018209 106 0.024
Human
regulation of cell motility GO:2000145 299 0.023
vesicle organization GO:0016050 62 0.023
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.023
regulation of meiotic cell cycle GO:0051445 4 0.023
regulation of kinase activity GO:0043549 314 0.023
Worm
purine nucleoside catabolic process GO:0006152 398 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
synaptic transmission cholinergic GO:0007271 2 0.023
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.023
cellular chemical homeostasis GO:0055082 180 0.023
cytokinesis GO:0000910 96 0.023
nuclear division GO:0000280 128 0.022
transmembrane transport GO:0055085 399 0.022
response to oxygen containing compound GO:1901700 369 0.022
cellular lipid metabolic process GO:0044255 303 0.022
embryo development ending in birth or egg hatching GO:0009792 34 0.022
Worm
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
synaptic vesicle exocytosis GO:0016079 3 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
mitotic sister chromatid separation GO:0051306 18 0.022
negative regulation of cell death GO:0060548 345 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
carbohydrate metabolic process GO:0005975 207 0.021
regulation of chromosome organization GO:0033044 103 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
sister chromatid segregation GO:0000819 54 0.021
viral process GO:0016032 146 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.021
peptidyl tyrosine modification GO:0018212 170 0.021
neurological system process GO:0050877 163 0.021
interspecies interaction between organisms GO:0044419 156 0.021
neurotransmitter secretion GO:0007269 4 0.021
developmental process involved in reproduction GO:0003006 66 0.020
hematopoietic or lymphoid organ development GO:0048534 186 0.020
spermatid differentiation GO:0048515 4 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
multicellular organism reproduction GO:0032504 42 0.020
regulation of anatomical structure size GO:0090066 101 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
negative regulation of protein modification process GO:0031400 200 0.020
regulation of protein acetylation GO:1901983 25 0.020
protein depolymerization GO:0051261 30 0.020
response to external biotic stimulus GO:0043207 261 0.019
Fly
microtubule based process GO:0007017 210 0.019
head development GO:0060322 108 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
positive regulation of catabolic process GO:0009896 310 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
negative regulation of protein maturation GO:1903318 142 0.019
Human
regulation of cell growth GO:0001558 135 0.019
regulation of hormone levels GO:0010817 125 0.019
endocytosis GO:0006897 159 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
nucleosome disassembly GO:0006337 12 0.019
metal ion transport GO:0030001 272 0.019
defense response GO:0006952 315 0.019
positive regulation of growth GO:0045927 58 0.019
Worm
chromatin remodeling GO:0006338 55 0.019
anterior posterior axis specification GO:0009948 2 0.019
positive regulation of mapk cascade GO:0043410 190 0.019
regulation of cell migration GO:0030334 289 0.019
rho protein signal transduction GO:0007266 26 0.019
regulation of protein maturation GO:1903317 150 0.019
Human
dephosphorylation GO:0016311 209 0.019
organophosphate catabolic process GO:0046434 430 0.018
regulation of cell projection organization GO:0031344 107 0.018
negative regulation of multicellular organismal process GO:0051241 317 0.018
response to ionizing radiation GO:0010212 65 0.018
Human
spermatid development GO:0007286 4 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
nucleoside catabolic process GO:0009164 408 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
Human
blastoderm segmentation GO:0007350 2 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.018
protein localization to membrane GO:0072657 160 0.018
regulation of dna metabolic process GO:0051052 153 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
regulation of cell morphogenesis GO:0022604 153 0.018
Fly
cell division GO:0051301 168 0.017
multicellular organismal reproductive process GO:0048609 40 0.017
mating GO:0007618 1 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
purine ribonucleotide biosynthetic process GO:0009152 79 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
single organism membrane fusion GO:0044801 37 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
cellular protein complex disassembly GO:0043624 36 0.017
regulation of mrna processing GO:0050684 48 0.017
secretion by cell GO:0032940 226 0.017
regulation of cellular component size GO:0032535 82 0.017
establishment of protein localization to membrane GO:0090150 121 0.017
positive regulation of meiotic cell cycle GO:0051446 2 0.016
negative regulation of developmental process GO:0051093 247 0.016
behavioral response to ethanol GO:0048149 2 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
positive regulation of immune system process GO:0002684 283 0.016
regulation of cell development GO:0060284 161 0.016
apoptotic signaling pathway GO:0097190 268 0.016
regulation of intracellular transport GO:0032386 195 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
actin cytoskeleton organization GO:0030036 207 0.016
nucleotide catabolic process GO:0009166 408 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
regulation of protein transport GO:0051223 213 0.016
wnt signaling pathway GO:0016055 156 0.016
positive regulation of cell cycle process GO:0090068 106 0.016
leukocyte activation GO:0045321 164 0.016
maintenance of location GO:0051235 112 0.016
tripartite regional subdivision GO:0007351 2 0.016
regulation of establishment of protein localization GO:0070201 242 0.015
double strand break repair GO:0006302 101 0.015
neuron projection morphogenesis GO:0048812 50 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
regulation of cell adhesion GO:0030155 166 0.015
stress activated mapk cascade GO:0051403 93 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
response to biotic stimulus GO:0009607 276 0.015
Fly
embryonic placenta development GO:0001892 1 0.015
cell activation GO:0001775 213 0.015
regulation of binding GO:0051098 111 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
negative regulation of cell cycle GO:0045786 193 0.015
negative regulation of organelle organization GO:0010639 126 0.015
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.015
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
embryonic morphogenesis GO:0048598 85 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
negative regulation of catabolic process GO:0009895 104 0.015
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
regulation of canonical wnt signaling pathway GO:0060828 88 0.015
regeneration GO:0031099 4 0.014
protein oligomerization GO:0051259 173 0.014
negative regulation of protein catabolic process GO:0042177 59 0.014
Human
cation transport GO:0006812 331 0.014
plasma membrane organization GO:0007009 115 0.014
ribonucleotide biosynthetic process GO:0009260 81 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
brain development GO:0007420 97 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
hindbrain development GO:0030902 3 0.014
regulation of response to external stimulus GO:0032101 222 0.014
response to nitrogen compound GO:1901698 184 0.014
hemopoiesis GO:0030097 180 0.014
ossification GO:0001503 121 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
peripheral nervous system development GO:0007422 2 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
rhythmic behavior GO:0007622 2 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
negative regulation of cellular protein catabolic process GO:1903363 38 0.014
Human
meiosis i GO:0007127 4 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of protein complex assembly GO:0043254 147 0.014
regulation of multi organism process GO:0043900 157 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
adult locomotory behavior GO:0008344 1 0.014
cellular carbohydrate metabolic process GO:0044262 84 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
positive regulation of cell death GO:0010942 263 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.014
microtubule polymerization or depolymerization GO:0031109 37 0.014
myeloid cell differentiation GO:0030099 117 0.014
negative regulation of immune system process GO:0002683 136 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
Human
negative regulation of notch signaling pathway GO:0045746 10 0.013
cytokine production GO:0001816 247 0.013
protein localization to organelle GO:0033365 280 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
cell projection assembly GO:0030031 126 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
golgi vesicle transport GO:0048193 80 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
multi organism cellular process GO:0044764 156 0.013
regulation of response to wounding GO:1903034 101 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
regulation of mrna splicing via spliceosome GO:0048024 32 0.013
blastocyst development GO:0001824 3 0.013
regulation of microtubule cytoskeleton organization GO:0070507 61 0.013
cellular response to ionizing radiation GO:0071479 32 0.013
Human
regulation of ion transport GO:0043269 189 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.013
regulation of cellular component movement GO:0051270 334 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
protein targeting GO:0006605 187 0.013
cellular component assembly involved in morphogenesis GO:0010927 73 0.013
negative regulation of synaptic transmission GO:0050805 2 0.012
vasculature development GO:0001944 181 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
regulation of protein localization GO:0032880 296 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
oxidation reduction process GO:0055114 396 0.012
peptide transport GO:0015833 74 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
viral life cycle GO:0019058 132 0.012
t cell activation GO:0042110 99 0.012
sequestering of metal ion GO:0051238 24 0.012
male gamete generation GO:0048232 22 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
tissue regeneration GO:0042246 3 0.012
cardiovascular system development GO:0072358 262 0.012
developmental programmed cell death GO:0010623 3 0.012
lipid metabolic process GO:0006629 381 0.012
regulation of membrane potential GO:0042391 95 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
regulation of stress activated mapk cascade GO:0032872 84 0.012
neural tube closure GO:0001843 3 0.012
stress activated protein kinase signaling cascade GO:0031098 94 0.012
limbic system development GO:0021761 3 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
ion transmembrane transport GO:0034220 338 0.012
glycoprotein metabolic process GO:0009100 110 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
epithelium development GO:0060429 227 0.012
cellular response to oxygen containing compound GO:1901701 276 0.011
sexual reproduction GO:0019953 37 0.011
response to oxygen levels GO:0070482 100 0.011
regulation of protein targeting GO:1903533 91 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
intracellular mrna localization GO:0008298 1 0.011
wound healing GO:0042060 115 0.011
stem cell division GO:0017145 2 0.011
positive regulation of proteolysis GO:0045862 142 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
primary neural tube formation GO:0014020 3 0.011
regulation of mitosis GO:0007088 63 0.011
tube closure GO:0060606 3 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
embryonic camera type eye development GO:0031076 2 0.011
spinal cord development GO:0021510 4 0.011
microtubule organizing center organization GO:0031023 62 0.011
dendrite morphogenesis GO:0048813 14 0.011
organelle assembly GO:0070925 176 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
response to cytokine GO:0034097 232 0.011
spermatogenesis GO:0007283 22 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
sleep GO:0030431 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
sequestering of calcium ion GO:0051208 17 0.011
jnk cascade GO:0007254 80 0.011
ion homeostasis GO:0050801 230 0.011
neuroblast proliferation GO:0007405 4 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
muscle contraction GO:0006936 73 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
autophagy GO:0006914 88 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
positive regulation of cytoskeleton organization GO:0051495 83 0.011
positive regulation of locomotion GO:0040017 186 0.011
central nervous system development GO:0007417 123 0.011
mitochondrion organization GO:0007005 156 0.011
protein import GO:0017038 130 0.011
divalent inorganic cation transport GO:0072511 158 0.010
nitrogen compound transport GO:0071705 191 0.010

TLK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.025
hematopoietic system disease DOID:74 100 0.025
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
organ system cancer DOID:0050686 164 0.014
sensory system disease DOID:0050155 203 0.014