Homo sapiens

28 known processes

TNFRSF10A

tumor necrosis factor receptor superfamily, member 10a

(Aliases: TRAILR-1,DR4,MGC9365,APO2,CD261,TRAILR1)

TNFRSF10A biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to increased oxygen levels GO:0036295 4 0.999
Human
skeletal muscle satellite cell proliferation GO:0014841 1 0.998
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.995
trail activated apoptotic signaling pathway GO:0036462 4 0.994
programmed necrotic cell death GO:0097300 18 0.985
Human
regulation of myoblast fusion GO:1901739 1 0.984
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.982
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.975
positive regulation of osteoclast differentiation GO:0045672 9 0.967
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.962
t cell apoptotic process GO:0070231 12 0.954
response to cobalt ion GO:0032025 1 0.940
lymphocyte apoptotic process GO:0070227 20 0.906
leukocyte apoptotic process GO:0071887 31 0.891
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.887
positive regulation of peptidase activity GO:0010952 88 0.876
extrinsic apoptotic signaling pathway GO:0097191 119 0.871
response to increased oxygen levels GO:0036296 4 0.868
Human
apoptotic mitochondrial changes GO:0008637 57 0.845
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.825
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.823
cellular response to abiotic stimulus GO:0071214 117 0.820
regulation of map kinase activity GO:0043405 108 0.807
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.804
positive regulation of apoptotic process GO:0043065 246 0.803
Human Zebrafish
regulation of cellular ketone metabolic process GO:0010565 50 0.800
regulation of peptidase activity GO:0052547 180 0.794
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.785
release of cytochrome c from mitochondria GO:0001836 35 0.783
positive regulation of nik nf kappab signaling GO:1901224 10 0.781
regulation of cellular amino acid metabolic process GO:0006521 6 0.780
regulation of myeloid cell differentiation GO:0045637 81 0.777
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.775
amine metabolic process GO:0009308 44 0.771
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.770
necroptotic process GO:0070266 16 0.766
Human
activation of nf kappab inducing kinase activity GO:0007250 9 0.756
positive regulation of jak stat cascade GO:0046427 35 0.751
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.745
protein processing GO:0016485 226 0.745
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.740
cell chemotaxis GO:0060326 112 0.739
cell type specific apoptotic process GO:0097285 125 0.737
negative regulation of cell death GO:0060548 345 0.734
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.734
regulation of cellular amine metabolic process GO:0033238 11 0.729
positive regulation of programmed cell death GO:0043068 249 0.727
Human Zebrafish
i kappab kinase nf kappab signaling GO:0007249 166 0.715
Human
cellular response to external stimulus GO:0071496 111 0.715
regulation of endopeptidase activity GO:0052548 170 0.705
positive regulation of hydrolase activity GO:0051345 331 0.701
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.693
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.679
response to hyperoxia GO:0055093 4 0.677
Human
regulation of endothelial cell apoptotic process GO:2000351 24 0.677
activation induced cell death of t cells GO:0006924 2 0.675
necroptotic signaling pathway GO:0097527 6 0.672
Human
positive regulation of endopeptidase activity GO:0010950 84 0.660
cellular amino acid metabolic process GO:0006520 116 0.657
positive regulation of bone resorption GO:0045780 2 0.655
cellular response to mechanical stimulus GO:0071260 39 0.653
negative regulation of apoptotic process GO:0043066 316 0.642
negative regulation of endopeptidase activity GO:0010951 84 0.642
positive regulation of apoptotic signaling pathway GO:2001235 70 0.618
necrotic cell death GO:0070265 21 0.610
Human
regulation of mitochondrion organization GO:0010821 54 0.608
peptidyl tyrosine modification GO:0018212 170 0.589
Human
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.584
regulation of cysteine type endopeptidase activity GO:2000116 127 0.577
intrinsic apoptotic signaling pathway GO:0097193 127 0.577
Human
positive regulation of proteolysis GO:0045862 142 0.575
cellular response to tumor necrosis factor GO:0071356 63 0.560
t cell homeostasis GO:0043029 3 0.559
protein maturation GO:0051604 233 0.531
regulation of proteolysis GO:0030162 293 0.527
negative regulation of t cell apoptotic process GO:0070233 4 0.520
apoptotic signaling pathway GO:0097190 268 0.517
erk1 and erk2 cascade GO:0070371 104 0.501
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.501
Human
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.500
positive regulation of cell cell adhesion GO:0022409 22 0.497
negative regulation of blood vessel morphogenesis GO:2000181 41 0.476
immune system development GO:0002520 195 0.476
leukocyte migration GO:0050900 107 0.470
cell fate determination GO:0001709 3 0.467
response to mechanical stimulus GO:0009612 51 0.463
positive regulation of nf kappab import into nucleus GO:0042346 13 0.458
negative regulation of response to wounding GO:1903035 47 0.456
Human
tyrosine phosphorylation of stat protein GO:0007260 33 0.452
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.451
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.448
Human
engulfment of apoptotic cell GO:0043652 2 0.447
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.441
Human
leukocyte differentiation GO:0002521 98 0.435
regulation of cell cycle arrest GO:0071156 36 0.425
endothelial cell apoptotic process GO:0072577 26 0.423
negative regulation of necroptotic process GO:0060546 2 0.419
response to abiotic stimulus GO:0009628 336 0.416
positive regulation of cell death GO:0010942 263 0.414
Human Zebrafish
positive regulation of protein phosphorylation GO:0001934 313 0.407
Human
negative regulation of peptidase activity GO:0010466 91 0.394
regulation of protein processing GO:0070613 150 0.392
regulation of homeostatic process GO:0032844 121 0.389
cellular response to hyperoxia GO:0071455 4 0.378
Human
negative regulation of synaptic transmission GO:0050805 2 0.358
positive regulation of t cell migration GO:2000406 13 0.353
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.351
Human
negative regulation of proteolysis GO:0045861 132 0.342
response to tumor necrosis factor GO:0034612 76 0.338
regulation of apoptotic signaling pathway GO:2001233 175 0.326
positive regulation of map kinase activity GO:0043406 80 0.318
positive regulation of protein kinase activity GO:0045860 190 0.318
cardiovascular system development GO:0072358 262 0.313
positive regulation of myeloid cell differentiation GO:0045639 39 0.309
regulation of protein targeting GO:1903533 91 0.306
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.305
Human
protein localization to nucleus GO:0034504 136 0.293
negative regulation of intracellular signal transduction GO:1902532 183 0.290
biological adhesion GO:0022610 331 0.290
neural tube formation GO:0001841 3 0.288
morphogenesis of embryonic epithelium GO:0016331 4 0.287
cellular response to cytokine stimulus GO:0071345 181 0.285
peptide transport GO:0015833 74 0.282
positive regulation of lymphocyte migration GO:2000403 16 0.281
jak stat cascade GO:0007259 46 0.278
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.277
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.277
regulation of lymphocyte activation GO:0051249 103 0.274
regulation of leukocyte differentiation GO:1902105 61 0.273
regulation of transcription factor import into nucleus GO:0042990 39 0.273
positive regulation of leukocyte activation GO:0002696 80 0.272
hemopoiesis GO:0030097 180 0.266
regulation of anatomical structure morphogenesis GO:0022603 286 0.263
regulation of nucleocytoplasmic transport GO:0046822 98 0.262
cytoplasmic sequestering of nf kappab GO:0007253 7 0.256
cellular ketone metabolic process GO:0042180 80 0.254
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.253
response to oxygen containing compound GO:1901700 369 0.247
regulation of protein transport GO:0051223 213 0.246
thymocyte apoptotic process GO:0070242 2 0.245
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.241
positive regulation of phosphorylation GO:0042327 394 0.239
Human
establishment of protein localization to organelle GO:0072594 172 0.237
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.236
response to endoplasmic reticulum stress GO:0034976 49 0.220
Human
regulation of osteoclast differentiation GO:0045670 18 0.211
male gonad development GO:0008584 23 0.211
regulation of response to external stimulus GO:0032101 222 0.209
Human
regulation of mapk cascade GO:0043408 262 0.193
regulation of necroptotic process GO:0060544 7 0.190
regulation of response to wounding GO:1903034 101 0.188
Human
regulation of cell cell adhesion GO:0022407 57 0.184
regulation of satellite cell proliferation GO:0014842 1 0.182
myeloid cell differentiation GO:0030099 117 0.181
regulation of inflammatory response GO:0050727 46 0.178
Human
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.177
zymogen activation GO:0031638 70 0.171
response to wounding GO:0009611 168 0.170
Human
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.170
negative regulation of vasculature development GO:1901343 43 0.169
regulation of defense response GO:0031347 154 0.169
Human
positive regulation of mitochondrion organization GO:0010822 30 0.167
maintenance of protein location in cell GO:0032507 56 0.166
chemotaxis GO:0006935 157 0.164
regulation of peptide transport GO:0090087 62 0.163
vasculature development GO:0001944 181 0.163
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.161
development of primary male sexual characteristics GO:0046546 23 0.159
regulation of t cell activation GO:0050863 77 0.157
regulation of angiogenesis GO:0045765 92 0.154
positive regulation of cell differentiation GO:0045597 211 0.154
nuclear transport GO:0051169 179 0.150
negative regulation of catalytic activity GO:0043086 335 0.150
spleen development GO:0048536 1 0.145
regulation of lymphocyte apoptotic process GO:0070228 15 0.145
positive regulation of cell cycle arrest GO:0071158 23 0.145
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.142
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.142
Human
negative regulation of programmed cell death GO:0043069 321 0.142
execution phase of apoptosis GO:0097194 32 0.141
positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling GO:0071848 2 0.139
blood vessel morphogenesis GO:0048514 162 0.138
regulation of lymphocyte migration GO:2000401 22 0.137
leukocyte chemotaxis GO:0030595 76 0.134
signal transduction by phosphorylation GO:0023014 297 0.133
positive regulation of homeostatic process GO:0032846 47 0.133
cytoplasmic transport GO:0016482 379 0.132
cellular protein catabolic process GO:0044257 261 0.131
cytokine mediated signaling pathway GO:0019221 109 0.131
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 8 0.131
Human
positive regulation of intracellular transport GO:0032388 104 0.128
tissue regeneration GO:0042246 3 0.127
single organism cell adhesion GO:0098602 179 0.126
positive regulation of adaptive immune response GO:0002821 21 0.125
response to biotic stimulus GO:0009607 276 0.124
anatomical structure formation involved in morphogenesis GO:0048646 284 0.123
muscle cell proliferation GO:0033002 35 0.122
positive regulation of organelle organization GO:0010638 195 0.121
blood vessel development GO:0001568 172 0.118
negative regulation of hydrolase activity GO:0051346 182 0.118
angiogenesis GO:0001525 147 0.118
cell activation GO:0001775 213 0.118
response to water GO:0009415 2 0.117
apoptotic cell clearance GO:0043277 12 0.117
response to external biotic stimulus GO:0043207 261 0.115
regulation of skeletal muscle cell proliferation GO:0014857 1 0.115
tissue homeostasis GO:0001894 63 0.114
regulation of cell differentiation GO:0045595 393 0.114
signal transduction by p53 class mediator GO:0072331 72 0.114
regulation of protein import into nucleus GO:0042306 78 0.113
protein targeting GO:0006605 187 0.110
positive regulation of immune system process GO:0002684 283 0.108
mitotic dna damage checkpoint GO:0044773 28 0.107
negative regulation of immune system process GO:0002683 136 0.105
nitrogen compound transport GO:0071705 191 0.105
cell cell signaling GO:0007267 155 0.103
negative regulation of protein import into nucleus GO:0042308 30 0.102
regulation of jak stat cascade GO:0046425 44 0.102
Human
response to oxygen levels GO:0070482 100 0.101
Human
negative regulation of myotube differentiation GO:0010832 4 0.101
neuron cellular homeostasis GO:0070050 3 0.101
tyrosine phosphorylation of stat1 protein GO:0042508 11 0.100
Human
regeneration GO:0031099 4 0.097
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.096
lymphocyte homeostasis GO:0002260 4 0.096
negative regulation of transport GO:0051051 176 0.094
midbrain development GO:0030901 45 0.093
negative regulation of angiogenesis GO:0016525 39 0.092
response to organonitrogen compound GO:0010243 156 0.092
regulation of cell activation GO:0050865 125 0.092
synaptic transmission GO:0007268 61 0.091
positive regulation of innate immune response GO:0045089 79 0.090
cellular response to oxygen levels GO:0071453 55 0.090
Human
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.089
negative regulation of apoptotic signaling pathway GO:2001234 97 0.088
regulation of cell cycle process GO:0010564 266 0.086
regulation of necrotic cell death GO:0010939 9 0.086
regulation of cell adhesion GO:0030155 166 0.086
positive regulation of cell motility GO:2000147 177 0.085
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.083
regulation of leukocyte apoptotic process GO:2000106 25 0.082
negative regulation of protein maturation GO:1903318 142 0.080
epithelium development GO:0060429 227 0.079
myoblast fusion GO:0007520 1 0.078
regulation of tumor necrosis factor production GO:0032680 43 0.078
myeloid leukocyte differentiation GO:0002573 60 0.078
regulation of striated muscle cell differentiation GO:0051153 25 0.077
mitotic cell cycle checkpoint GO:0007093 68 0.076
negative regulation of developmental process GO:0051093 247 0.075
activation of cysteine type endopeptidase activity GO:0097202 57 0.075
nuclear import GO:0051170 106 0.075
actomyosin structure organization GO:0031032 59 0.073
cellular amine metabolic process GO:0044106 41 0.073
homotypic cell cell adhesion GO:0034109 47 0.072
mitotic cell cycle process GO:1903047 286 0.072
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 13 0.071
activated t cell proliferation GO:0050798 13 0.070
regulation of vasculature development GO:1901342 97 0.069
developmental process involved in reproduction GO:0003006 66 0.069
signal transduction in response to dna damage GO:0042770 57 0.068
negative regulation of nf kappab import into nucleus GO:0042347 12 0.068
negative regulation of leukocyte apoptotic process GO:2000107 16 0.068
skeletal muscle cell proliferation GO:0014856 1 0.067
positive regulation of mapk cascade GO:0043410 190 0.067
response to organic cyclic compound GO:0014070 204 0.066
defense response to bacterium GO:0042742 63 0.066
single organism cellular localization GO:1902580 332 0.066
mitochondrion organization GO:0007005 156 0.065
phenol containing compound metabolic process GO:0018958 12 0.065
positive regulation of transport GO:0051050 336 0.065
protein homooligomerization GO:0051260 100 0.064
negative regulation of protein localization to nucleus GO:1900181 34 0.064
muscle tissue development GO:0060537 62 0.064
transcription factor import into nucleus GO:0042991 40 0.064
regulation of erk1 and erk2 cascade GO:0070372 99 0.063
response to other organism GO:0051707 261 0.063
regulation of mononuclear cell proliferation GO:0032944 65 0.061
positive regulation of mononuclear cell proliferation GO:0032946 47 0.061
t cell migration GO:0072678 16 0.060
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.059
regulation of protein kinase activity GO:0045859 289 0.058
positive regulation of cell activation GO:0050867 81 0.058
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.058
cytokine metabolic process GO:0042107 38 0.058
negative regulation of mitotic cell cycle GO:0045930 102 0.058
membrane organization GO:0061024 292 0.058
cell cycle g1 s phase transition GO:0044843 80 0.057
muscle system process GO:0003012 81 0.057
activation of protein kinase activity GO:0032147 90 0.056
tissue morphogenesis GO:0048729 96 0.055
maintenance of location GO:0051235 112 0.055
regulation of t cell apoptotic process GO:0070232 8 0.055
positive regulation of cell migration GO:0030335 172 0.055
positive regulation of cellular component organization GO:0051130 376 0.054
negative regulation of protein metabolic process GO:0051248 391 0.054
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.054
regulation of cell cycle GO:0051726 393 0.054
central nervous system development GO:0007417 123 0.054
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.054
positive regulation of transferase activity GO:0051347 227 0.054
negative regulation of muscle cell differentiation GO:0051148 17 0.053
stress activated mapk cascade GO:0051403 93 0.053
defense response to other organism GO:0098542 129 0.052
cellular response to cobalt ion GO:0071279 1 0.052
response to radiation GO:0009314 151 0.052
myeloid leukocyte migration GO:0097529 62 0.052
cell cycle phase transition GO:0044770 173 0.051
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 4 0.050
head development GO:0060322 108 0.050
negative regulation of cell cycle GO:0045786 193 0.049
regulation of leukocyte migration GO:0002685 63 0.049
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.049
cellular response to dna damage stimulus GO:0006974 379 0.049
regulation of intracellular transport GO:0032386 195 0.049
brain development GO:0007420 97 0.048
leukocyte activation GO:0045321 164 0.047
organic hydroxy compound metabolic process GO:1901615 147 0.047
striated muscle cell differentiation GO:0051146 43 0.047
response to cytokine GO:0034097 232 0.047
positive regulation of leukocyte migration GO:0002687 46 0.046
negative regulation of inflammatory response GO:0050728 22 0.046
Human
morphogenesis of an epithelium GO:0002009 60 0.046
t cell differentiation in thymus GO:0033077 4 0.045
positive regulation of leukocyte differentiation GO:1902107 37 0.045
innate immune response GO:0045087 178 0.045
response to bacterium GO:0009617 144 0.045
circulatory system development GO:0072359 262 0.045
post embryonic development GO:0009791 2 0.044
thymus development GO:0048538 3 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
regulation of kinase activity GO:0043549 314 0.043
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.043
sex differentiation GO:0007548 45 0.042
muscle structure development GO:0061061 98 0.042
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.041
negative regulation of protein processing GO:0010955 142 0.041
stress activated protein kinase signaling cascade GO:0031098 94 0.039
negative regulation of cytoplasmic transport GO:1903650 46 0.039
defense response to gram negative bacterium GO:0050829 14 0.039
system process GO:0003008 349 0.039
ion transmembrane transport GO:0034220 338 0.039
positive regulation of transcription factor import into nucleus GO:0042993 25 0.039
negative regulation of phosphate metabolic process GO:0045936 267 0.039
interferon gamma production GO:0032609 39 0.038
organelle assembly GO:0070925 176 0.038
positive regulation of bone remodeling GO:0046852 2 0.038
regulation of macrophage differentiation GO:0045649 9 0.037
response to hormone GO:0009725 175 0.037
nervous system development GO:0007399 293 0.037
determination of adult lifespan GO:0008340 2 0.037
dna damage checkpoint GO:0000077 68 0.037
erythrocyte differentiation GO:0030218 28 0.036
regulation of cellular component movement GO:0051270 334 0.036
hematopoietic or lymphoid organ development GO:0048534 186 0.036
positive regulation of locomotion GO:0040017 186 0.036
neuron apoptotic process GO:0051402 39 0.036
response to lipid GO:0033993 206 0.035
secondary metabolic process GO:0019748 17 0.035
regulation of response to dna damage stimulus GO:2001020 94 0.035
toll like receptor 2 signaling pathway GO:0034134 4 0.035
cellular macromolecule catabolic process GO:0044265 380 0.035
regulation of type i interferon mediated signaling pathway GO:0060338 9 0.035
protein oligomerization GO:0051259 173 0.035
negative regulation of defense response GO:0031348 47 0.034
Human
inflammatory cell apoptotic process GO:0006925 3 0.034
tumor necrosis factor mediated signaling pathway GO:0033209 27 0.034
ketone catabolic process GO:0042182 3 0.033
regulation of myeloid leukocyte differentiation GO:0002761 39 0.033
regulation of cellular response to stress GO:0080135 244 0.032
regulation of protein maturation GO:1903317 150 0.032
nucleocytoplasmic transport GO:0006913 176 0.032
positive regulation of cytokine mediated signaling pathway GO:0001961 12 0.032
positive regulation of cellular component movement GO:0051272 181 0.032
lymphocyte mediated immunity GO:0002449 48 0.031
embryonic epithelial tube formation GO:0001838 4 0.031
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.031
t cell mediated cytotoxicity GO:0001913 9 0.031
cellular response to organonitrogen compound GO:0071417 124 0.031
tube development GO:0035295 125 0.031
substantia nigra development GO:0021762 45 0.031
epithelial tube morphogenesis GO:0060562 38 0.031
cell cycle arrest GO:0007050 71 0.031
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.031
cellular response to water stimulus GO:0071462 1 0.031
negative regulation of homeostatic process GO:0032845 59 0.030
eye photoreceptor cell differentiation GO:0001754 2 0.030
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.030
macrophage differentiation GO:0030225 11 0.029
regulation of transferase activity GO:0051338 355 0.029
single organism nuclear import GO:1902593 104 0.029
striated muscle tissue development GO:0014706 59 0.029
regulation of cell cycle g1 s phase transition GO:1902806 42 0.029
response to drug GO:0042493 81 0.029
regulation of synaptic transmission GO:0050804 11 0.029
mitotic cell cycle phase transition GO:0044772 162 0.029
response to nitrogen compound GO:1901698 184 0.029
taxis GO:0042330 157 0.029
adaptive immune response GO:0002250 49 0.029
pigment metabolic process GO:0042440 16 0.029
positive regulation of cell cycle process GO:0090068 106 0.028
protein import GO:0017038 130 0.028
cellular response to endogenous stimulus GO:0071495 336 0.028
mitotic cell cycle GO:0000278 326 0.028
maintenance of protein location GO:0045185 57 0.028
neural nucleus development GO:0048857 47 0.028
cellular response to metal ion GO:0071248 43 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
oogenesis GO:0048477 2 0.027
defense response GO:0006952 315 0.027
Human
growth GO:0040007 202 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.026
proteasomal protein catabolic process GO:0010498 176 0.026
regulation of homotypic cell cell adhesion GO:0034110 8 0.025
negative regulation of intracellular protein transport GO:0090317 42 0.025
positive regulation of immune response GO:0050778 159 0.024
regulation of cell cycle phase transition GO:1901987 126 0.024
protein catabolic process GO:0030163 325 0.024
negative regulation of cellular component organization GO:0051129 235 0.024
t cell differentiation GO:0030217 29 0.024
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.024
regulation of cytoplasmic transport GO:1903649 149 0.024
response to virus GO:0009615 126 0.024
primary neural tube formation GO:0014020 3 0.024
chromatin organization GO:0006325 351 0.023
cytoplasmic sequestering of transcription factor GO:0042994 9 0.023
syncytium formation by plasma membrane fusion GO:0000768 2 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
negative regulation of cell cycle phase transition GO:1901988 89 0.023
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.023
cellular response to radiation GO:0071478 65 0.023
circadian behavior GO:0048512 2 0.023
female gamete generation GO:0007292 2 0.023
organophosphate biosynthetic process GO:0090407 163 0.023
regulation of establishment of protein localization GO:0070201 242 0.022
protein complex localization GO:0031503 31 0.022
positive regulation of cell adhesion GO:0045785 84 0.022
regulation of intracellular protein transport GO:0033157 123 0.022
negative regulation of protein transport GO:0051224 75 0.022
response to light stimulus GO:0009416 87 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.022
cell cycle checkpoint GO:0000075 117 0.022
actin cytoskeleton organization GO:0030036 207 0.022
chemical homeostasis GO:0048878 306 0.022
type i interferon signaling pathway GO:0060337 11 0.022
positive regulation of protein transport GO:0051222 135 0.022
interleukin 8 production GO:0032637 51 0.022
reproductive process GO:0022414 106 0.021
regulation of activated t cell proliferation GO:0046006 12 0.021
protein targeting to nucleus GO:0044744 104 0.021
response to alcohol GO:0097305 64 0.021
cellular component assembly involved in morphogenesis GO:0010927 73 0.021
multicellular organismal aging GO:0010259 3 0.021
vesicle mediated transport GO:0016192 371 0.021
response to metal ion GO:0010038 84 0.020
regulation of tissue remodeling GO:0034103 9 0.020
regulation of neuron death GO:1901214 56 0.020
tnfsf11 mediated signaling pathway GO:0071847 2 0.020
positive regulation of kinase activity GO:0033674 204 0.020
spermatid development GO:0007286 4 0.020
intracellular protein transport GO:0006886 270 0.020
cellular response to lipid GO:0071396 127 0.020
inflammatory response GO:0006954 79 0.020
Human
cellular lipid metabolic process GO:0044255 303 0.020
small molecule catabolic process GO:0044282 92 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
positive regulation of t cell proliferation GO:0042102 33 0.020
nf kappab import into nucleus GO:0042348 22 0.020
locomotory behavior GO:0007626 1 0.020
leukocyte mediated cytotoxicity GO:0001909 27 0.020
mitotic g1 dna damage checkpoint GO:0031571 17 0.019
positive regulation of cell cycle GO:0045787 140 0.019
segmentation GO:0035282 4 0.019
positive regulation of lymphocyte activation GO:0051251 73 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.019

TNFRSF10A disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.882
Human
cancer DOID:162 167 0.782
Human
organ system cancer DOID:0050686 164 0.312
Human
immune system disease DOID:2914 155 0.138
Human
gastrointestinal system cancer DOID:3119 52 0.121
thoracic cancer DOID:5093 21 0.063
stomach cancer DOID:10534 12 0.053
hepatocellular carcinoma DOID:684 9 0.053
liver carcinoma DOID:686 9 0.053
liver cancer DOID:3571 9 0.053
disease of metabolism DOID:0014667 295 0.033
breast cancer DOID:1612 21 0.029
musculoskeletal system disease DOID:17 223 0.028
sensory system disease DOID:0050155 203 0.026
eye and adnexa disease DOID:1492 150 0.026
nervous system disease DOID:863 431 0.026
Human
eye disease DOID:5614 149 0.026
inherited metabolic disorder DOID:655 242 0.026
hypersensitivity reaction type iv disease DOID:2916 6 0.022
Human
hypersensitivity reaction disease DOID:0060056 25 0.022
Human
connective tissue disease DOID:65 109 0.020